-
1
-
-
0030272689
-
Telomerase and cancer: Revisiting the telomere hypothesis
-
Autexier, C. and Greider, C.W. (1996) Telomerase and cancer: revisiting the telomere hypothesis. Trends Biochem., 21, 387-391.
-
(1996)
Trends Biochem.
, vol.21
, pp. 387-391
-
-
Autexier, C.1
Greider, C.W.2
-
2
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn, E.H. (1991) Structure and function of telomeres. Nature, 350, 569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
3
-
-
0029154735
-
Functional characterization and developmental regulation of mouse telomerase RNA
-
Blasco, M.A., Funk, W.D., Villeponteau, B. and Greider, C.W. (1995) Functional characterization and developmental regulation of mouse telomerase RNA. Science, 269, 1267-1270.
-
(1995)
Science
, vol.269
, pp. 1267-1270
-
-
Blasco, M.A.1
Funk, W.D.2
Villeponteau, B.3
Greider, C.W.4
-
4
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco, M.A., Lee, H.-W., Hande, P., Samper, E., Lansdorp, P., DePinho, R. and Greider, C.W. (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell, 91, 25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.-W.2
Hande, P.3
Samper, E.4
Lansdorp, P.5
DePinho, R.6
Greider, C.W.7
-
5
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar, A.G. et al. (1998) Extension of life-span by introduction of telomerase into normal human cells. Science, 279, 349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
-
6
-
-
0029940570
-
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow
-
Chiu, C.P., Dragowska, W., Kim, N.W., Vaziri, H., Yui, J., Thomas, T.E., Harley, C.B. and Lansdorp, P.M. (1996) Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells, 14, 239-48.
-
(1996)
Stem Cells
, vol.14
, pp. 239-248
-
-
Chiu, C.P.1
Dragowska, W.2
Kim, N.W.3
Vaziri, H.4
Yui, J.5
Thomas, T.E.6
Harley, C.B.7
Lansdorp, P.M.8
-
7
-
-
0028990123
-
Purification of Tetrahymena telomerase and cloning of the genes for the two protein components of the enzyme
-
Collins, K., Kobayashi, R. and Greider, C.W. (1995) Purification of Tetrahymena telomerase and cloning of the genes for the two protein components of the enzyme. Cell, 81, 677-686.
-
(1995)
Cell
, vol.81
, pp. 677-686
-
-
Collins, K.1
Kobayashi, R.2
Greider, C.W.3
-
8
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter, C.M., Avilion, A.A., LeFeuvre, C.E., Stewart, N.G., Greider, C.W., Harley, C.B. and Bacchetti, S. (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J., 11, 1921-1929.
-
(1992)
EMBO J.
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
LeFeuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
9
-
-
0029096515
-
The RNA component of human telomerase
-
Feng, J. et al. (1995) The RNA component of human telomerase. Science, 269, 1236-1241.
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
-
10
-
-
0032030840
-
Interaction of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates
-
Gandhi, L. and Collins, K. (1998) Interaction of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates. Genes Dev., 12, 721-733.
-
(1998)
Genes Dev.
, vol.12
, pp. 721-733
-
-
Gandhi, L.1
Collins, K.2
-
11
-
-
0032473931
-
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation
-
Greenberg, R.A., Allsopp, R.C., Chin, L., Morin, G. and DePinho, R. (1998) Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation. Oncogene, 16, 1723-1730.
-
(1998)
Oncogene
, vol.16
, pp. 1723-1730
-
-
Greenberg, R.A.1
Allsopp, R.C.2
Chin, L.3
Morin, G.4
Depinho, R.5
-
12
-
-
0029894237
-
Telomere length regulation
-
Greider, C.W. (1996) Telomere length regulation. Annu. Rev. Biochem., 65, 337-365.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 337-365
-
-
Greider, C.W.1
-
13
-
-
0024978857
-
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
-
Greider, C.W. and Blackburn, E.H. (1989) A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature, 337, 331-337.
-
(1989)
Nature
, vol.337
, pp. 331-337
-
-
Greider, C.W.1
Blackburn, E.H.2
-
14
-
-
0033593814
-
Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice
-
Hande, P., Samper, E., Lansdorp, P. and Blasco, M.A. (1999) Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice. J. Cell Biol., 144, 589-601.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 589-601
-
-
Hande, P.1
Samper, E.2
Lansdorp, P.3
Blasco, M.A.4
-
15
-
-
0028557213
-
Stringent sequence requirements for the formation of human telomeres
-
Hanish, J.P., Yanowitz, J.L. and de Lange, T. (1995) Stringent sequence requirements for the formation of human telomeres. Proc. Natl Acad. Sci. USA, 91, 8861-8865.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 8861-8865
-
-
Hanish, J.P.1
Yanowitz, J.L.2
De Lange, T.3
-
16
-
-
0025279931
-
Telomeres shorten during aging of human fibroblasts
-
Harley, C.B., Futcher, A.B. and Greider, C.W. (1990) Telomeres shorten during aging of human fibroblasts. Nature, 345, 458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
17
-
-
0030668722
-
Human telomerase contains evolutionarily conserved catalytic and structural subunits
-
Harrington, L., Zhou, W., McPhail, T., Oulton, R., Yeung, D., Mar, V., Bass, M.B. and Robinson, W. (1997a) Human telomerase contains evolutionarily conserved catalytic and structural subunits. Genes Dev., 11, 3109-3115.
-
(1997)
Genes Dev.
, vol.11
, pp. 3109-3115
-
-
Harrington, L.1
Zhou, W.2
McPhail, T.3
Oulton, R.4
Yeung, D.5
Mar, V.6
Bass, M.B.7
Robinson, W.8
-
18
-
-
0031036350
-
A mammalian telomerase-associated protein
-
Harrington, L., McPhail, T., Mar, V., Zhou, W., Oulton, R., Bass, M.B., Arruda, I. and Robinson, M.O. (1997b) A mammalian telomerase-associated protein. Science, 275, 973-977.
-
(1997)
Science
, vol.275
, pp. 973-977
-
-
Harrington, L.1
McPhail, T.2
Mar, V.3
Zhou, W.4
Oulton, R.5
Bass, M.B.6
Arruda, I.7
Robinson, M.O.8
-
19
-
-
0033104511
-
-/- embryos is associated with failure to close the neural tube
-
-/- embryos is associated with failure to close the neural tube. EMBO J., 18, 1172-1181.
-
(1999)
EMBO J.
, vol.18
, pp. 1172-1181
-
-
Herrera, E.1
Samper, E.2
Blasco, M.A.3
-
20
-
-
0029091386
-
Activation of telomerase in human lymphocytes and hematopoietic progenitor cells
-
Hiyama, K., Hirai, Y., Kyoizumi, S., Akiyama, M., Hiyama, E., Piatyszek, M.A., Shay, J.W., Ishioka, S. and Yamakido, M. (1995) Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J. Immunol., 155, 3711-3715.
-
(1995)
J. Immunol.
, vol.155
, pp. 3711-3715
-
-
Hiyama, K.1
Hirai, Y.2
Kyoizumi, S.3
Akiyama, M.4
Hiyama, E.5
Piatyszek, M.A.6
Shay, J.W.7
Ishioka, S.8
Yamakido, M.9
-
21
-
-
0032923742
-
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
-
Jiang, X.-R. et al. (1999) Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nature Genet., 21, 111-114.
-
(1999)
Nature Genet.
, vol.21
, pp. 111-114
-
-
Jiang, X.-R.1
-
22
-
-
0030681073
-
Isolation of a candidate human telomerase catalytic subunit gene. Which reveals complex splicing patterns in different cell types
-
Kilian, A., Bowtell, D.D.L., Abud, H.E., Hime, G.R., Venter, D.J., Keese, P.K., Duncan, E.L., Reddel, R.R. and Jefferson, R.A. (1997) Isolation of a candidate human telomerase catalytic subunit gene. which reveals complex splicing patterns in different cell types. Hum. Mol. Genet., 6, 2011-2019.
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 2011-2019
-
-
Kilian, A.1
Bowtell, D.D.L.2
Abud, H.E.3
Hime, G.R.4
Venter, D.J.5
Keese, P.K.6
Duncan, E.L.7
Reddel, R.R.8
Jefferson, R.A.9
-
23
-
-
0032487675
-
INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
-
INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature, 396, 84-88.
-
(1998)
Nature
, vol.396
, pp. 84-88
-
-
Kiyono, T.1
Foster, S.A.2
Koop, J.I.3
McDougall, J.K.4
Galloway, D.A.5
Klingelhutz, A.J.6
-
24
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee, H.-W., Blasco, M.A., Gottlieb, G.J., Horner, J.W., Greider, C.W. and DePinho, R.A. (1998) Essential role of mouse telomerase in highly proliferative organs. Nature, 392, 569-574.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.-W.1
Blasco, M.A.2
Gottlieb, G.J.3
Horner, J.W.4
Greider, C.W.5
DePinho, R.A.6
-
25
-
-
0030938901
-
Reverse transcriptase motifs in the catalytic subunit of telomerase
-
Lingner, J., Hughes, T.R., Schevchenko, A., Mann, M., Lundblad, V. and Cech, T. (1997) Reverse transcriptase motifs in the catalytic subunit of telomerase. Science, 276, 561-567.
-
(1997)
Science
, vol.276
, pp. 561-567
-
-
Lingner, J.1
Hughes, T.R.2
Schevchenko, A.3
Mann, M.4
Lundblad, V.5
Cech, T.6
-
26
-
-
0031984598
-
Short telomeres on human chromosome 17p
-
Martens, U.M., Zijlmans, J.M., Poon, S., Dragowska, W., Yui, J., Chavez, E., Ward, R. and Lansdorp, P.M. (1998) Short telomeres on human chromosome 17p. Nature Genet., 18, 76-80.
-
(1998)
Nature Genet.
, vol.18
, pp. 76-80
-
-
Martens, U.M.1
Zijlmans, J.M.2
Poon, S.3
Dragowska, W.4
Yui, J.5
Chavez, E.6
Ward, R.7
Lansdorp, P.M.8
-
27
-
-
0032168370
-
Expression of mouse telomerase catalytic subunit in embryos and adult tissues
-
Martín-Rivera, L., Herrera, E., Albar, J.P. and Blasco, M.A. (1998) Expression of mouse telomerase catalytic subunit in embryos and adult tissues. Proc. Natl Acad. Sci. USA, 95, 10471-10476.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 10471-10476
-
-
Martín-Rivera, L.1
Herrera, E.2
Albar, J.P.3
Blasco, M.A.4
-
28
-
-
0029102354
-
Runaway telomere elongation caused by telomerase RNA gene mutations
-
McEachern, M.J. and Blackburn, E.H. (1995) Runaway telomere elongation caused by telomerase RNA gene mutations. Nature, 376, 403-409.
-
(1995)
Nature
, vol.376
, pp. 403-409
-
-
McEachern, M.J.1
Blackburn, E.H.2
-
29
-
-
0030745448
-
hEST2, the putative human telomerase catalytic subunit gene, is upregulated in tumor cells and during immortalization
-
Meyerson, M. et al. (1997) hEST2, the putative human telomerase catalytic subunit gene, is upregulated in tumor cells and during immortalization. Cell, 90, 785-795.
-
(1997)
Cell
, vol.90
, pp. 785-795
-
-
Meyerson, M.1
-
31
-
-
0032924343
-
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
-
Morales, C.P., Holt, S.E., Ouellette, M., Kaur, K.J., Yan, Y., Wilson, K.S., White, M.A., Wright, W.E. and Shay, J.W. (1999) Absence of cancer-associated changes in human fibroblasts immortalized with telomerase. Nature Genet., 21, 115-118.
-
(1999)
Nature Genet.
, vol.21
, pp. 115-118
-
-
Morales, C.P.1
Holt, S.E.2
Ouellette, M.3
Kaur, K.J.4
Yan, Y.5
Wilson, K.S.6
White, M.A.7
Wright, W.E.8
Shay, J.W.9
-
32
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura, T.M., Morin, G.B., Chapman, K.B., Weinrich, S.L., Andrews, W.H., Lingner, J., Harley, C.B. and Cech, T. (1997) Telomerase catalytic subunit homologs from fission yeast and human. Science, 277, 955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.8
-
33
-
-
3543142313
-
Two modes of survival of fission yeast without telomerase
-
Nakamura, T.M., Cooper, J.P. and Cech, T. (1998) Two modes of survival of fission yeast without telomerase. Science, 282, 493-496.
-
(1998)
Science
, vol.282
, pp. 493-496
-
-
Nakamura, T.M.1
Cooper, J.P.2
Cech, T.3
-
34
-
-
0030898989
-
TLP1: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeat family
-
Nakayama, J., Saito, M., Nakamura, H., Matsuura, A. and Ishikawa, F. (1997) TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeat family. Cell, 88, 875-884.
-
(1997)
Cell
, vol.88
, pp. 875-884
-
-
Nakayama, J.1
Saito, M.2
Nakamura, H.3
Matsuura, A.4
Ishikawa, F.5
-
35
-
-
0031810555
-
Severe growth defect in mouse cells lacking the telomerase RNA component
-
Niida, H., Matsumoto, T., Satoh, H., Shiwa, M., Tokutake, Y., Furuici, Y. and Shinkai, Y. (1998) Severe growth defect in mouse cells lacking the telomerase RNA component. Nature Genet., 19, 203-206.
-
(1998)
Nature Genet.
, vol.19
, pp. 203-206
-
-
Niida, H.1
Matsumoto, T.2
Satoh, H.3
Shiwa, M.4
Tokutake, Y.5
Furuici, Y.6
Shinkai, Y.7
-
36
-
-
0020038913
-
Hyperplasia and immature appearance of sertoli-cells in primary testicular disorders
-
Nistal, M., Paniagua, R., Abaurrea, M.A. and Santamaría, L. (1982) Hyperplasia and immature appearance of Sertoli-cells in primary testicular disorders. Hum. Pathol., 13, 3-12.
-
(1982)
Hum. Pathol.
, vol.13
, pp. 3-12
-
-
Nistal, M.1
Paniagua, R.2
Abaurrea, M.A.3
Santamaría, L.4
-
37
-
-
0032522443
-
The telomerase reverse transcriptase: Components and regulation
-
Nugent, C.I. and Lundblad, V. (1998) The telomerase reverse transcriptase: components and regulation, Genes Dev., 12, 1073-1085.
-
(1998)
Genes Dev.
, vol.12
, pp. 1073-1085
-
-
Nugent, C.I.1
Lundblad, V.2
-
38
-
-
0033525558
-
Longevity, stress response and cancer in aging telomerase deficient mice
-
Rudolph, K.L., Chang, S., Lee, H.-W., Blasco, M.A., Gottlieb, G., Greider, W.C. and DePinho, R.A. (1999) Longevity, stress response and cancer in aging telomerase deficient mice. Cell, 96, 701-712.
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.-W.3
Blasco, M.A.4
Gottlieb, G.5
Greider, W.C.6
DePinho, R.A.7
-
39
-
-
0027944347
-
TLC1: Template RNA component of the Saccharomyces cerevisiae telomerase
-
Singer, M.S. and Gottschling, D.E. (1994) TLC1: template RNA component of the Saccharomyces cerevisiae telomerase. Science, 266, 387-388.
-
(1994)
Science
, vol.266
, pp. 387-388
-
-
Singer, M.S.1
Gottschling, D.E.2
-
40
-
-
0004134537
-
-
Wolfe Publishing, London, UK
-
Smith, C.A., Andrews, C.M., Collard, J.K., Hall, D.E., Walker, A.K. and Wolfe, M. (1994) Color Atlas of Comparative Diagnostic and Experimental Hematology. Wolfe Publishing, London, UK.
-
(1994)
Color Atlas of Comparative Diagnostic and Experimental Hematology
-
-
Smith, C.A.1
Andrews, C.M.2
Collard, J.K.3
Hall, D.E.4
Walker, A.K.5
Wolfe, M.6
-
42
-
-
0023505260
-
Age-related histologic changes in the adult mouse testis
-
Takano, H. and Abe, K. (1987) Age-related histologic changes in the adult mouse testis. Arch. Histol. Japan, 50, 533-544.
-
(1987)
Arch. Histol. Japan
, vol.50
, pp. 533-544
-
-
Takano, H.1
Abe, K.2
-
43
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
Vaziri, H., Schachter, F. and Uchida, I. (1993) Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am. J. Hum. Genet., 52, 661-667.
-
(1993)
Am. J. Hum. Genet.
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schachter, F.2
Uchida, I.3
-
44
-
-
2642610318
-
Myc activates telomerase
-
Wang, J., Xie, L.Y., Allan, S., Beach, D. and Hannon, G.J. (1998) Myc activates telomerase. Genes Dev., 12,1769-1774.
-
(1998)
Genes Dev.
, vol.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
Beach, D.4
Hannon, G.J.5
-
45
-
-
0031448878
-
Primary and secondary alterations of immune reactivity in the elderly: Impact of dietary factors and disease
-
Wick, G. and Grubeck-Loebenstein, B. (1997) Primary and secondary alterations of immune reactivity in the elderly: impact of dietary factors and disease. Immunol. Rev., 160, 171-184.
-
(1997)
Immunol. Rev.
, vol.160
, pp. 171-184
-
-
Wick, G.1
Grubeck-Loebenstein, B.2
-
46
-
-
0030737882
-
Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats
-
Zijlmans, J.M., Martens, U.M., Poon, S., Raap, A.K., Tanke, H.J., Ward, R.K. and Lansdorp, P.M. (1997) Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats. Proc. Natl Acad. Sci. USA, 94, 7423-7428.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 7423-7428
-
-
Zijlmans, J.M.1
Martens, U.M.2
Poon, S.3
Raap, A.K.4
Tanke, H.J.5
Ward, R.K.6
Lansdorp, P.M.7
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