The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1

Genes and Development

Volumn 15, Issue 23, 2001, Pages 3155-3168

  Osada, Shigehiro ^a,b   Sutton, Ann ^c   Muster, Nemone ^d   Brown, Christine E ^a   Yates III, John R ^d   Sternglanz, Rolf ^c   Workman, Jerry L ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b OSAKA UNIVERSITY   (Japan)

^c STONY BROOK UNIVERSITY   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Acetyl transferase; ASF1; Chromatin assembly factor; MYST; SAS; Silencing

Indexed keywords

ACETYL COENZYME A; ACYLTRANSFERASE; HISTONE; NONHISTONE PROTEIN; PROTEIN SAS; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CHROMATIN; ENZYME ACTIVITY; GENE SILENCING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE; TELOMERE;

ACETYLTRANSFERASES; AMINO ACID SEQUENCE; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CHROMATIN; CROSSES, GENETIC; DNA DAMAGE; DNA REPLICATION; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENE SILENCING; HISTONE ACETYLTRANSFERASES; MACROMOLECULAR SUBSTANCES; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUTAGENESIS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SILENT INFORMATION REGULATOR PROTEINS, SACCHAROMYCES CEREVISIAE; TRANS-ACTIVATORS; TRANSFORMATION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 0035576789     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.907201     Document Type: Article

References (55)

1. NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esalp and the ATM-related cofactor Tralp
2. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
3. Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae
4. The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein
5. The many HATs of transcription coactivators
6. TFG/TAF30/ANC1, a component of the yeast SWI/SNF complex that is similar to the leukemogenic proteins ENL and AF-9
7. Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein
8. Targeting Sir proteins to sites of action: A general mechanism for regulated repression
9. Control of the histone-acetyltransferase activity of Tip60 by the HIV-1 transactivator protein
10. Initiation of DNA replication in eukaryotic cells
11. Identification and analysis of yeast nucleosomal histone acetyltransferase complexes
12. The role of Sas2, an acetyltransferase homologue of Saccharomyces cerevisiae, in silencing and ORC function
13. The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcriptional regulation
14. Dynamic interaction of DNA damage checkpoint protein Rad53 with chromatin assembly factor Asf1
15. Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci
16. Cloning of a novel transcription factor-like gene amplified in human glioma including astrocytoma grade I
17. Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription
18. A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation
19. Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae
20. GAS41, a highly conserved protein in eukaryotic nuclei, binds to NuMA
21. TFIIF-TAF-RNA polymerase II connection
22. Histone acetyltransferase complexes and their link to transcription
23. Asf1 links Rad53 to control of chromatin assembly
24. Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein
25. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis
26. II30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex
27. Type B histone acetyltransferase Hatlp participates in telomeric silencing
28. Two new S-phase-specific genes from Saccharomyces cerevisiae
29. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
30. Mechanisms of silencing in Saccharomyces cerevisiae
31. Yeast homologues of higher eukaryotic TFIID subunits
32. Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast
33. A human homologue of yeast anti-silencing factor has histone chaperone activity
34. Potential topoisomerase II DNA-binding sites at the breakpoints of a t(9;11) chromosome translocation in acute myeloid leukemia
35. Epigenetic inheritance of transcriptional states in S. cerevisiae
36. Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases
37. Androgen receptor interacts with a novel MYST protein, HBO1
38. An uncertain silence
39. Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae
40. ESA1 is a histone acetyltransferase that is essential for growth in yeast
41. The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation
42. Assay of yeast mating reaction
43. Acetylation of histones and transcription-related factors
44. A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae
45. Yeast ASF1 protein is required for cell-cycle regulation of histone gene transcription
46. Sas3 is a histone acetyltransferase and requires a zinc finger motif
47. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
48. The RCAF complex mediates chromatin assembly during DNA replication and repair
49. Heterologous HIS3 marker and GFP reporter modules for PCR-targeting in Saccharomyces cerevisiae
50. Identification of SAS4 and SAS5, two genes that regulate silencing in Saccharomyces cerevisiae
51. SAS4 and SAS5 are locus-specific regulators of silencing in Saccharomyces cerevisiae
52. Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60
53. Crystal structure of yeast esal suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases