Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease

Experimental Neurology

Volumn 218, Issue 2, 2009, Pages 235-246

  Büeler, Hansruedi ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alpha synuclein; DJ 1; Environmental factors; Familial Parkinson disease genes; HtrA2; LRRK2; Mitochondrial DNA deletions; Mitochondrial dynamics; Mitochondrial dysfunction; Omi; Oxidative stress; Parkin; Parkinson's disease; PINK1; TRAP1

Indexed keywords

ALPHA SYNUCLEIN; CELL PROTEIN; DJ 1 PROTEIN; DOPAMINE; LEUCINE RICH REPEAT KINASE 2; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; PARKIN; PTEN INDUCED PUTATIVE KINASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SERINE PROTEINASE OMI; UNCLASSIFIED DRUG;

AGING; APOPTOSIS; CELL STRESS; CELL SURVIVAL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOPAMINE METABOLISM; DOPAMINERGIC NERVE CELL; ENERGY YIELD; GENE MUTATION; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MITOCHONDRIAL RESPIRATION; MUTATIONAL ANALYSIS; NERVE CELL NECROSIS; NEUROTRANSMISSION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN TRANSPORT; REVIEW; SUBSTANTIA NIGRA; SYNAPTIC TRANSMISSION;

ALPHA-SYNUCLEIN; ANIMALS; APOPTOSIS; ELECTRON TRANSPORT COMPLEX I; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MUTATION; ONCOGENE PROTEINS; OXIDATIVE STRESS; PARKINSON DISEASE; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; UBIQUITIN-PROTEIN LIGASES;

EID: 67649756320     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.03.006     Document Type: Review

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