Effects of paraquat on mitochondrial electron transport system and catecholamine contents in rat brain

Archives of Toxicology

Volumn 70, Issue 9, 1996, Pages 585-589

  Tawara, Toshinaga ^a   Fukushima, Tetsuhito ^a   Hojo, Nobumasa ^a   Isobe, Akio ^a   Shiwaku, Kuninori ^a   Setogawa, Tomoichi ^a   Yamane, Yosuke ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

Catecholamine; Central nervous system; Complex I; Lipid peroxidation; Paraquat

Indexed keywords

CATECHOLAMINE; DOPAMINE; NORADRENALIN; PARAQUAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; ELECTRON TRANSPORT; LIPID PEROXIDATION; LIVER; LUNG; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CATECHOLAMINES; ELECTRON TRANSPORT; HERBICIDES; MALE; MITOCHONDRIA; PARAQUAT; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030004770     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050316     Document Type: Article

References (30)

1. + and paraquat in rana pipiens. Life Sci 37: 1529-1538
2. Bindoff LA, Birch-Machin M, Cartlidge NEF, Parker WD, Turnbull DM (1989) Mitochondrial function in Parkinson's disease. Lancet 2: 49
3. Blaszczyński M, Litwińska J, Zaborowska D, Biliński T (1985) The role of respiratory chain in paraquat toxicity in yeast. Acta Microbiol Polon 34: 243-254
4. Bus JS, Aust SD, Gibson JE (1974) Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity. Biochem Biophys Res Commun 58 [3]: 749-755
5. Clejan L, Cederbaum AI (1989) Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals. Biochem Pharmacol 38 [11]: 1779-1786
6. Corasaniti MT, Strongoli MC, Nistico G (1990) Determination of paraquat in rat brain using ion-pair solid-phase extraction and reversed-phase high-performance liquid chromatography with ultraviolet detection. J Chromatogr 527: 189-195
7. Fukushima T, Yamada K, Hojo N, Isobe A, Shiwaku K, Yamane Y (1993) Mechanism of cytotoxicity of paraquat I: NADH oxidation and paraquat radical formation via complex I. Exp Toxicol Pathol 45: 345-349
8. Fukushima T, Yamada K, Hojo N, Isobe A, Shiwaku K, Yamane Y (1994) Mechanism of cytotoxicity of paraquat III: The effects of acute paraquat exposure on the electron transport system in rat mitochondria. Exp Toxicol Pathol 46: 437-441
9. 3H] DOPA in various regions of the brain. J Neurochem 13: 655-669
10. Gornall AG, Bardawill CS, David MN (1949) Determination of serum proteins by means of the biuret reaction. J Biol Chem 177: 751-766
11. Grant HC, Lantos PL, Parkinson C (1980) Cerebral damage in paraquat poisoning. Histopathology 4: 185-195
12. Grcěvić N, Jadro-Šantel D, Jukić S (1977) Cerebral changes in paraquat poisoning. In: Neurotoxicology. Raven Press, New York, pp 469-484
13. Hirai K, Witschi H, Cote MG (1985) Mitochondrial injury of pulmonary alveolar epithelial cells in acute paraquat intoxication. Exp Mol Pathol 43: 242-252
14. Hughes JT (1988) Brain damage due to paraquat poisoning: a fatal case with neuropathological examination of the brain. Neurotoxicology 9: 243-248
15. Ikarashi Y, Maruyama Y, Stavinoha WB (1984) Study of the use of the microwave magnetic field for the rapid inactivation of brain enzymes. Jpn J Pharmacol 35: 371-387
16. Kato R, Iwasaki K, Noguchi H (1976) Stimulatory effect of FMN and methyl viologen on cytochrome P-450 dependent reduction of tertiary amine N-oxide. Biochem Biophys Res Commun 72 [1]: 267-274
17. Koller WC (1986) Paraquat and Parkinson's disease. Neurology 36: 1147
18. Markey SP, Weisz A, Bacon JP (1986) Reduced paraquat does not exhibit MPTP-like neurotoxicity. J Anal Toxicol 10: 256
19. Mitsui A, Nohta H, Ohkura Y (1985) High-performance liquid chromatography of plasma catecholamines using 1,2-diphenyl-ethylenediamine as pre-column fluorescence derivatization reagent. J Chromatogr 344: 61-70
20. Mizuno Y, Ohta S, Tanaka M, Takamiya S, Suzuki K, Sato T, Oya H, Ozawa T, Kagawa Y (1989) Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease. Biochem Biophys Res Commun 163: 1450-1455
21. Mukada T, Sasano N, Sato K (1978) Autopsy findings in a case of acute paraquat poisoning with extensive cerebral purpura. Tohoku J Exp Med 125: 253-263
22. Nagao M, Takatori T, Wu B, Terazawa K, Gotouda H, Akabane H (1991) Immunohistochemical localization of paraquat in lung and brain. Med Sci Law 31 [1]: 61-64
23. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358
24. Parker WD, Boyson SJ, Parks JK (1989) Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann Neurol 26: 719-723
25. Rose MS, Lock EA, Smith LL, Wyatt I (1976) Paraquat accumulation: tissue and species specificity. Biochem Pharmacol 25: 419-423
26. Singer TP, Ramsay RR (1990) Mechanism of the neurotoxicity of MPTP. An update. FEBS Lett 274: 1-8
27. +) and paraquat on isolated mitochondria from rat striatum, cortex and liver. Life Sci 43: 143-149
28. Tomita M (1991) Comparison of one-electron reduction activity against the bipyridylium herbicides, paraquat and diquat, in microsomal and mitochondrial fractions of liver, lung and kidney (in vitro). Biochem Pharmacol 42: 303-309
29. Turrens JF, Boveris A (1980) Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem J 191: 421-427
30. Yamada K, Fukushima T (1993) Mechanism of cytotoxicity of paraquat II: organ specificity of paraquat-stimulated lipid peroxidation in the inner membrane of mitochondria. Exp Toxicol Pathol 45: 375-380