Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 24, 2000, Pages 13354-13359

  Zhang, Yi ^a   Gao, Jun ^a   Chung, Kenny K K ^a   Huang, Hui ^a   Dawson, Valina L ^a   Dawson, Ted M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PARKIN; PROTEIN; PROTEIN CDCREL 1; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KIDNEY CELL CULTURE; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; SYNAPSE VESICLE;

AMINO ACID SEQUENCE; BINDING SITES; CELL CYCLE PROTEINS; CELL LINE; CLONING, MOLECULAR; HUMANS; LIGASES; METHIONINE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PARKINSON DISEASE; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SYNAPTIC VESICLES; TRANSFECTION; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 0034700158     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.240347797     Document Type: Article

References (45)

1. Lang, A. E. & Lozano, A. M. (1998) N. Engl. J. Med. 339, 1044-1053.
2. Lang, A. E. & Lozano, A. M. (1998) N. Engl. J. Med. 339, 1130-1143.
3. Jenner, P. & Olanow, C. W. (1998) Ann. Neurol. 44, S72-S84.
4. Dunnett, S. B. & Bjorklund, A. (1999) Nature (London) 399, A32-A39.
5. Pollanen, M. S., Dickson, D. W. & Bergeron, C. (1993) J. Neuropathol. Exp. Neurol. 52, 183-91.
6. Zhang, Y., Dawson, V. L. & Dawson, T. M. (2000) Neurobiol. Dis. 7, 240-250.
7. Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., et al. (1997) Science 276, 2045-2047.
8. Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J. T., Schols, L. & Riess, O. (1998) Nat. Genet. 18, 106-108.
9. Spillantini, M. G., Schmidt, M. L., Lee, V. M., Trojanowski, J. Q., Jakes, R. & Goedert, M. (1997) Nature (London) 388, 839-840.
10. Trojanowski, J. Q., Goedert, M., Iwatsubo, T. & Lee, V. M. (1998) Cell Death Differ. 5, 832-837.
11. Masliah, E., Rockenstein, E., Veinbergs, I., Mallory, M., Hashimoto, M., Takeda, A., Sagara, Y., Sisk, A. & Mucke, L. (2000) Science 287, 1265-1269.
12. Feany, M. B. & Bender, W. W. (2000) Nature (London) 404, 394-398.
13. Dawson, T. M. (2000) Cell 101, 115-118.
14. Leroy, E., Boyer, R., Auburger, G., Leube, B., Ulm, G., Mezey, E., Harta, G., Brownstein, M. J., Jonnalagada, S., Chernova, T., et al. (1998) Nature (London) 395, 451-452.
15. Farrer, M., Gwinn-Hardy, K., Muenter, M., DeVrieze, F. W., Crook, R., Perez-Tur, J., Lincoln, S., Maraganore, D., Adler, C., Newman, S., et al. (1999) Hum. Mol. Genet. 8, 81-85.
16. Gasser, T., Muller-Myhsok, B., Wszolek, Z. K., Oehlmann, R., Calne, D. B., Bonifati, V., Bereznai, B., Fabrizio, E., Vieregge, P. & Horstmann, R. D. (1998) Nat. Genet. 18, 262-265.
17. Gwinn-Hardy, K. A., Crook, R., Lincoln, S., Adler, C. H., Caviness, J. N., Hardy, J. & Farrer, M. (2000) Neurology 54, 504-507.
18. Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., Yokochi, M., Mizuno, Y. & Shimizu, N. (1998) Nature (London) 392, 605-608.
19. Lucking, C. B., Durr, A., Bonifati, V., Vaughan, J. R., De Michele, G., Gasser, T., Harhangi, B. S., Meco, G., Denefle, P., Wood, N. W., et al. (2000) N. Engl. J. Med. 342, 1560-1567.
20. Lucking, C. B., Abbas, N., Durr, A., Bonifati, V., Bonnet, A. M., de Broucker, T., De Michele, G., Wood, N. W., Agid, Y. & Brice, A. (1998) Lancet 352, 1355-1356.
21. Abbas, N., Lucking, C. B., Ricard, S., Durr, A., Bonifati, V., De Michele, G., Bouley, S., Vaughan, J. R., Gasser, T., Marconi, R., et al. (1999) Hum. Mol. Genet. 8, 567-574.
22. Morett, E. & Bork, P. (1999) Trends Biochem. Sci. 24, 229-231.
23. Kornitzer, D. & Ciechanover, A. (2000) J. Cell Physiol. 182, 1-11.
24. Ciechanover, A., Orian, A. & Schwartz, A. L. (2000) BioEssays 22, 442-451.
25. Joazeiro, C. A., Wing, S. S., Huang, H., Leverson, J. D., Hunter, T. & Liu, Y. C. (1999) Science 286, 309-312.
26. Lorick, K. L., Jensen, J. P., Fang, S., Ong, A. M., Hatakeyama, S. & Weissman, A. M. (1999) Proc. Natl. Acad. Sci. USA 96, 11364-11369.
27. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W. & Lipman, D. J. (1997) Nucleic Acids Res. 25, 3389-3402.
28. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Press, Plainview, NY), 2nd Ed.
29. Moynihan, T. P., Ardley, H. C., Nuber, U., Rose, S. A., Jones, P. F., Markham, A. F., Scheffner, M. & Robinson, P. A. (1999) J. Biol. Chem. 274, 30963-30968.
30. Martinez-Noel, G., Niedenthal, R., Tamura, T. & Harbers, K. (1999) FEBS Lett. 454, 257-261.
31. Kimura, M., Hattori, T., Matsuda, Y., Yoshioka, T., Sumi, N., Umeda, Y., Nakashima, S. & Okano, Y. (1997) Cytogenet. Cell Genet. 78, 107-111.
32. Fang, S., Jensen, J. P., Ludwig, R. L., Vousden, K. H. & Weissman, A. M. (2000) J. Biol. Chem. 275, 8945-8951.
33. Beites, C. L., Xie, H., Bowser, R. & Trimble, W. S. (1999) Nat. Neurosci. 2, 434-439.
34. Shimura, H., Hattori, N., Kubo, S., Mizuno, Y., Asakawa, S., Minoshima, S., Shimizu, N., Iwai, K., Chiba, T., Tanaka, K., et al. (2000) Nat. Genet. 25, 302-305.
35. Katsanis, N. & Fisher, E. M. (1998) Genomics 51, 128-131.
36. Trimble, W. S. (1999) J. Membr. Biol. 169, 75-81.
37. Field, C. M. & Kellogg, D. (1999) Trends Cell Biol. 9, 387-394.
38. Beesley, P. W., Mummery, R., Tibaldi, J., Chapman, A. P., Smith, S. J. & Rider, C. C. (1995) Biochem. Soc. Trans. 23, 59-64.
39. Chapman, A. P., Smith, S. J., Rider, C. C. & Beesley, P. W. (1994) Neurosci. Lett. 168, 238-242.
40. Chapman, A. P., Courtney, S. C., Smith, S. J., Rider, C. C. & Beesley, P. W. (1992) Biochem. Soc. Trans. 20, 155S.
41. Kinoshita, A., Kinoshita, M., Akiyama, H., Tomimoto, H., Akiguchi, I., Kumar, S., Noda, M. & Kimura, J. (1998) Am. J. Pathol. 153, 1551-1560.
42. Galloway, P. G., Mulvihill, P. & Perry, G. (1992) Am. J. Pathol. 140, 809-822.
43. Takahashi, H., Ohama, E., Suzuki, S., Horikawa, Y., Ishikawa, A., Morita, T., Tsuji, S. & Ikuta, F. (1994) Neurology 44, 437-441.
44. Mori, H., Kondo, T., Yokochi, M., Matsumine, H., Nakagawa-Hattori, Y., Miyake, T., Suda, K. & Mizuno, Y. (1998) Neurology 51, 890-892.
45. Ishikawa, A. & Takahashi, H. (1998) J. Neurol. 245, 4-9.