α-synuclein, especially the parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

Journal of Molecular Biology

Volumn 322, Issue 5, 2002, Pages 1089-1102

  Lashuel, Hilal A ^a   Petre, Benjamin M ^a   Wall, Joseph ^b   Simon, Martha ^b   Nowak, Richard J ^a   Walz, Thomas ^a   Lansbury Jr, Peter T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

Parkinson's disease; Protofibrils; Scanning transmission electron microscopy; Transmission electron microscopy; synuclein

Indexed keywords

ALPHA SYNUCLEIN;

ARTICLE; CYTOTOXICITY; DISEASE ASSOCIATION; HUMAN; MEMBRANE PERMEABILITY; MORPHOLOGY; MUTATION; NONHUMAN; ONSET AGE; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; SCANNING TRANSMISSION ELECTRON MICROSCOPY; ULTRACENTRIFUGATION; WILD TYPE;

EID: 0036415838     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00735-0     Document Type: Article

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