MicroRNAs as targets for antisense-based therapeutics

Expert Opinion on Biological Therapy

Volumn 8, Issue 1, 2008, Pages 59-81

  Stenvang, Jan ^a   Kauppinen, Sakari ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Santaris Pharma AS   (Denmark)

Author keywords

2 O methoxyethyl; 2 O methyl; AnrimiR; Antagomir; Antisense oligonucleorides; ASO; LNA; Locked nucleic acid; microRNA; miRNA

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CHOLESTEROL; DOXORUBICIN; FOMIVIRSEN; GLUCOSE; INSULIN; LIPOSOME; LOCKED NUCLEIC ACID; MESSENGER RNA; MICRORNA; MORPHOLINO OLIGONUCLEOTIDE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; OLIGOMER; OLIGONUCLEOTIDE; SINGLE STRANDED RNA; SMALL INTERFERING RNA; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ADIPOCYTE; ANTINEOPLASTIC ACTIVITY; ANTISENSE THERAPY; ANTIVIRAL ACTIVITY; BASE PAIRING; CELL ACTIVITY; CELL DIFFERENTIATION; CELL FATE; CELL GROWTH; CHEMICAL STRUCTURE; CLINICAL TRIAL; DIABETES MELLITUS; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG SAFETY; DRUG TARGETING; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENE LOCATION; GENETIC TRANSCRIPTION; HEART INFARCTION; HEART VENTRICLE HYPERTROPHY; HEPATITIS C VIRUS; HUMAN; HYPERCHOLESTEROLEMIA; INSULIN RELEASE; MALIGNANT NEOPLASTIC DISEASE; MUSCLE CELL; MUSCLE DEVELOPMENT; NONHUMAN; OBESITY; OSTEOBLAST; PROTEIN FUNCTION; REVIEW; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STEM CELL; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; VIRUS REPLICATION; ANIMAL; DRUG ANTAGONISM; GENE TARGETING; GENE THERAPY; GENETICS; NEOPLASM;

ANIMALS; GENE TARGETING; GENE THERAPY; HUMANS; MICRORNAS; NEOPLASMS; OLIGONUCLEOTIDES, ANTISENSE;

EID: 38949133928     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.8.1.59     Document Type: Review

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