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Volumn 7, Issue 12, 2006, Pages 911-920

The neuronal microRNA system

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; NUCLEOTIDE;

EID: 33751254116     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn2037     Document Type: Review
Times cited : (709)

References (108)
  • 1
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B. P. et al. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20 (2005).
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1
  • 2
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • Krichevsky, A. M. et al. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9, 1274-1281 (2003).
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1
  • 3
    • 5344273958 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in the developing mammalian brain
    • Miska, E. et al. Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol. 5, R68 (2004).
    • (2004) Genome Biol. , vol.5
    • Miska, E.1
  • 4
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere, L. F. et al. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 5, R13 (2004).
    • (2004) Genome Biol. , vol.5
    • Sempere, L.F.1
  • 5
    • 0346458628 scopus 로고    scopus 로고
    • Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
    • Kim, J. et al. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc. Natl Acad. Sci. USA 101, 360-365 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 360-365
    • Kim, J.1
  • 6
    • 0037197803 scopus 로고    scopus 로고
    • Identification of tissue-specific microRNA's from mouse
    • Lagos-Quintana, M. et al. Identification of tissue-specific microRNA's from mouse. Curr. Biol. 12, 735-739 (2002).
    • (2002) Curr. Biol. , vol.12 , pp. 735-739
    • Lagos-Quintana, M.1
  • 7
    • 33749070342 scopus 로고    scopus 로고
    • Recognition and cleavage of primary microRNA transcripts
    • Zeng, Y. & Cullen, B. R. Recognition and cleavage of primary microRNA transcripts. Methods Mol. Biol. 342, 49-56 (2006).
    • (2006) Methods Mol. Biol. , vol.342 , pp. 49-56
    • Zeng, Y.1    Cullen, B.R.2
  • 8
    • 12544255565 scopus 로고    scopus 로고
    • Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
    • Zeng, Y., Yi, R. & Cullen, B. R. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J. 24, 138-148 (2005).
    • (2005) EMBO J. , vol.24 , pp. 138-148
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3
  • 9
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi, R. et al. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17, 3011-3016 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 3011-3016
    • Yi, R.1
  • 10
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear export of microRNA precursors
    • Lund, E. et al. Nuclear export of microRNA precursors. Science 303, 95-98 (2004).
    • (2004) Science , vol.303 , pp. 95-98
    • Lund, E.1
  • 11
    • 22744433240 scopus 로고    scopus 로고
    • Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
    • Forstemann, K. et al. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol. 3, e236 (2005).
    • (2005) PLoS Biol. , vol.3
    • Forstemann, K.1
  • 12
    • 22744454230 scopus 로고    scopus 로고
    • Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells
    • Saito, K. et al. Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol. 3, e235 (2005).
    • (2005) PLoS Biol. , vol.3
    • Saito, K.1
  • 13
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 14
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • He, L. & Hannon, G. L. MicroRNAs: small RNAs with a big role in gene regulation. Nature Rev. Genet. 5, 522-531 (2004).
    • (2004) Nature Rev. Genet. , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.L.2
  • 16
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim, L. P. et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature, 433, 769-773 (2005). An important study that suggested the global control of miRNAs over cell identity and the first to show a widespread effect of miRNAs on mRNA stability.
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1
  • 17
    • 23944514849 scopus 로고    scopus 로고
    • Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation
    • Bagga, S. et al. Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 122, 553-563 (2005).
    • (2005) Cell , vol.122 , pp. 553-563
    • Bagga, S.1
  • 18
    • 20044388720 scopus 로고    scopus 로고
    • Involvement of microRNA in AU-rich element-mediated mRNA instability
    • Jing, Q. et al. Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 120, 623-634 (2005).
    • (2005) Cell , vol.120 , pp. 623-634
    • Jing, Q.1
  • 19
    • 0042124978 scopus 로고    scopus 로고
    • Identification of eight members of the Argonaute family in the human genome small star, filled
    • Sasaki, T. et al. Identification of eight members of the Argonaute family in the human genome small star, filled. Genomics 82, 323-330 (2003).
    • (2003) Genomics , vol.82 , pp. 323-330
    • Sasaki, T.1
  • 20
    • 4444368187 scopus 로고    scopus 로고
    • Argonaute2 is the catalytic engine of mammalian RNAi
    • Liu, J. et al. Argonaute2 is the catalytic engine of mammalian RNAi. Science 305, 1437-1441 (2004).
    • (2004) Science , vol.305 , pp. 1437-1441
    • Liu, J.1
  • 21
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC slicer activity
    • Song, J. J. et al. Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305, 1434-1437 (2004).
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1
  • 22
    • 3142729150 scopus 로고    scopus 로고
    • Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
    • Okamura, K. et al. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev. 18, 1655-1666 (2004).
    • (2004) Genes Dev. , vol.18 , pp. 1655-1666
    • Okamura, K.1
  • 23
    • 0036792769 scopus 로고    scopus 로고
    • Fragile X-related protein and VIG associate with the RNA interference machinery
    • Caudy, A. A. et al. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev. 16, 2491-2496 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 2491-2496
    • Caudy, A.A.1
  • 24
    • 0141843655 scopus 로고    scopus 로고
    • A micrococcal nuclease homologue in RNAi effector complexes
    • Caudy, A. A. et al. A micrococcal nuclease homologue in RNAi effector complexes. Nature 425, 411-414 (2003).
    • (2003) Nature , vol.425 , pp. 411-414
    • Caudy, A.A.1
  • 25
    • 0141868916 scopus 로고    scopus 로고
    • R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
    • Liu, Q. et al. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301, 1921-1925 (2003).
    • (2003) Science , vol.301 , pp. 1921-1925
    • Liu, Q.1
  • 26
    • 0037087780 scopus 로고    scopus 로고
    • miRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
    • Mourelatos, Z. et al. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 16, 720-728 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 720-728
    • Mourelatos, Z.1
  • 27
    • 1642603943 scopus 로고    scopus 로고
    • RISC assembly defects in the Drosophila RNAi mutant armitage
    • Tomari, Y. et al. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116, 831-841 (2004).
    • (2004) Cell , vol.116 , pp. 831-841
    • Tomari, Y.1
  • 28
    • 33745894330 scopus 로고    scopus 로고
    • Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54
    • Chu, C. Y. & Rana, T. M. Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol. 4, e210 (2006).
    • (2006) PLoS Biol. , vol.4
    • Chu, C.Y.1    Rana, T.M.2
  • 29
    • 28544431919 scopus 로고    scopus 로고
    • A role for the P-body component GW182 in microRNA function
    • Liu, J. et al. A role for the P-body component GW182 in microRNA function. Nature Cell Biol. 7, 1261-1266 (2005).
    • (2005) Nature Cell Biol. , vol.7 , pp. 1261-1266
    • Liu, J.1
  • 30
    • 20444427566 scopus 로고    scopus 로고
    • Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
    • Sen, G. L. & Blau, H. M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nature Cell Biol. 7, 633-636 (2005).
    • (2005) Nature Cell Biol. , vol.7 , pp. 633-636
    • Sen, G.L.1    Blau, H.M.2
  • 31
    • 33749519058 scopus 로고    scopus 로고
    • Formation of GW bodies is a consequence of microRNA genesis
    • Pauley, K. M. et al. Formation of GW bodies is a consequence of microRNA genesis. EMBO Rep. 7, 904-910 (2006).
    • (2006) EMBO Rep. , vol.7 , pp. 904-910
    • Pauley, K.M.1
  • 32
    • 0347986572 scopus 로고    scopus 로고
    • Clinical and serological associations of autoantibodies to GW bodies and a novel cytoplasmic autoantigen GW182
    • Eystathioy, T. et al. Clinical and serological associations of autoantibodies to GW bodies and a novel cytoplasmic autoantigen GW182. J. Mol. Med. 81, 811-818 (2003).
    • (2003) J. Mol. Med. , vol.81 , pp. 811-818
    • Eystathioy, T.1
  • 33
    • 23744492247 scopus 로고    scopus 로고
    • The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans
    • Ding, L. et al. The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. Mol. Cell 19, 437-447 (2005).
    • (2005) Mol. Cell , vol.19 , pp. 437-447
    • Ding, L.1
  • 34
    • 0019509303 scopus 로고
    • Mutations that lead to reiterations in the cell lineages of C. elegans
    • Chalfie, M., Horvitz, H. R. & Sulston, J. E. Mutations that lead to reiterations in the cell lineages of C. elegans. Cell 24, 59-69 (1981).
    • (1981) Cell , vol.24 , pp. 59-69
    • Chalfie, M.1    Horvitz, H.R.2    Sulston, J.E.3
  • 35
    • 0024963695 scopus 로고
    • A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans
    • Ambros, V. A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans. Cell 57, 49-57 (1989).
    • (1989) Cell , vol.57 , pp. 49-57
    • Ambros, V.1
  • 36
    • 33749236251 scopus 로고    scopus 로고
    • MicroRNA: A new player in stem cells
    • Zhang, B., Pan, X. & Anderson, T. A. MicroRNA: a new player in stem cells. J. Cell Physiol. 209, 266-269 (2006).
    • (2006) J. Cell Physiol. , vol.209 , pp. 266-269
    • Zhang, B.1    Pan, X.2    Anderson, T.A.3
  • 37
    • 0035043250 scopus 로고    scopus 로고
    • Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily
    • Kataoka, Y., Takeichi, M. & Uemura, T. Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily. Genes Cells 6, 313-325 (2001).
    • (2001) Genes Cells , vol.6 , pp. 313-325
    • Kataoka, Y.1    Takeichi, M.2    Uemura, T.3
  • 38
    • 28944438404 scopus 로고    scopus 로고
    • Modulating Hox gene functions during animal body patterning
    • Pearson, J. C., Lemons, D. & McGinnis, W. Modulating Hox gene functions during animal body patterning. Nature Rev. Genet. 6, 893-904 (2005).
    • (2005) Nature Rev. Genet. , vol.6 , pp. 893-904
    • Pearson, J.C.1    Lemons, D.2    McGinnis, W.3
  • 39
    • 29144509665 scopus 로고    scopus 로고
    • Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development
    • Aboobaker, A. A. et al. Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development. Proc. Natl Acad. Sci. USA 102, 18017-18022 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 18017-18022
    • Aboobaker, A.A.1
  • 40
    • 6944246368 scopus 로고    scopus 로고
    • MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression
    • Mansfield, J. H. et al. MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nature Genet. 36, 1079-1083 (2004). A highly novel method to detect miRNA expression patterns in the whole organism.
    • (2004) Nature Genet. , vol.36 , pp. 1079-1083
    • Mansfield, J.H.1
  • 41
    • 29144438977 scopus 로고    scopus 로고
    • The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings
    • Ronshaugen, M. et al. The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings. Genes Dev. 19, 2947-2952 (2005).
    • (2005) Genes Dev. , vol.19 , pp. 2947-2952
    • Ronshaugen, M.1
  • 42
    • 33645525964 scopus 로고    scopus 로고
    • MicroRNA fingerprints during human megakaryocytopoiesis
    • Garzon, R. et al. MicroRNA fingerprints during human megakaryocytopoiesis. Proc. Natl Acad. Sci. USA 103, 5078-5083 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 5078-5083
    • Garzon, R.1
  • 43
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • Yekta, S., Shih, I. H. & Bartel, D. P. MicroRNA-directed cleavage of HOXB8 mRNA. Science 304, 594-596 (2004). Deepened interest in an important feature of the HOX gene loci, specifically the relationship between the physical location of a gene and its function.
    • (2004) Science , vol.304 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 44
    • 0037012082 scopus 로고    scopus 로고
    • Capecchi Hoxb8 is required for normal grooming behavior in mice
    • Greer, J. M. & M. R. Capecchi Hoxb8 is required for normal grooming behavior in mice. Neuron 33, 23-34 (2002).
    • (2002) Neuron , vol.33 , Issue.1 , pp. 23-34
    • Greer, J.M.1    Capecchi, M.R.2
  • 45
    • 18244385475 scopus 로고    scopus 로고
    • MicroRNAs regulate brain morphogenesis in zebrafish
    • Giraldez, A. J. et al. MicroRNAs regulate brain morphogenesis in zebrafish. Science 308, 833-838 (2005).
    • (2005) Science , vol.308 , pp. 833-838
    • Giraldez, A.J.1
  • 46
    • 22044458072 scopus 로고    scopus 로고
    • MicroRNA expression in zebrafish embryonic development
    • Wienholds, E. et al. MicroRNA expression in zebrafish embryonic development. Science 309, 310-311 (2005).
    • (2005) Science , vol.309 , pp. 310-311
    • Wienholds, E.1
  • 47
    • 21244448730 scopus 로고    scopus 로고
    • Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development
    • Leaman, D. et al. Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell 121, 1097-1108 (2005).
    • (2005) Cell , vol.121 , pp. 1097-1108
    • Leaman, D.1
  • 48
    • 0242266620 scopus 로고    scopus 로고
    • Dicer is essential for mouse development
    • Bernstein, E. et al. Dicer is essential for mouse development. Nature Genet. 35, 215-217 (2003).
    • (2003) Nature Genet. , vol.35 , pp. 215-217
    • Bernstein, E.1
  • 49
    • 0347357618 scopus 로고    scopus 로고
    • A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans
    • Johnston, R. J. & Hobert, O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature 426, 845-849 (2003).
    • (2003) Nature , vol.426 , pp. 845-849
    • Johnston, R.J.1    Hobert, O.2
  • 50
    • 24144437052 scopus 로고    scopus 로고
    • MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision
    • Johnston, R. J. Jr et al. MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision. Proc. Natl Acad. Sci. USA 102 12449-12454 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 12449-12454
    • Johnston Jr., R.J.1
  • 51
    • 4043072675 scopus 로고    scopus 로고
    • MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode
    • Chang, S. et al. MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode. Nature 430, 785-789 (2004). The above three studies from the Hobert lab are among the clearest demonstrations of miRNA circuitry and the complex relationship between miRNAs and transcription factors.
    • (2004) Nature , vol.430 , pp. 785-789
    • Chang, S.1
  • 52
    • 33645968725 scopus 로고    scopus 로고
    • Identification of new central nervous system specific mouse microRNAs
    • Wheeler, G. et al. Identification of new central nervous system specific mouse microRNAs. FEBS Lett. 580, 2195-2200 (2006).
    • (2006) FEBS Lett. , vol.580 , pp. 2195-2200
    • Wheeler, G.1
  • 53
    • 24644489402 scopus 로고    scopus 로고
    • MicroRNA profiling of the murine hematopoietic system
    • Monticelli, S. et al. MicroRNA profiling of the murine hematopoietic system. Genome Biol. 6, R71 (2005).
    • (2005) Genome Biol. , vol.6
    • Monticelli, S.1
  • 54
    • 33745480963 scopus 로고    scopus 로고
    • Specific microRNAs modulate embryonic stem cell-derived neurogenesis
    • Krichevsky, A. M. et al. Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 24, 857-864 (2006).
    • (2006) Stem Cells , vol.24 , pp. 857-864
    • Krichevsky, A.M.1
  • 55
    • 18444415448 scopus 로고    scopus 로고
    • Regulation of miRNA expression during neural cell specification
    • Smirnova, L. et al. Regulation of miRNA expression during neural cell specification. Eur. J. Neurosci. 21, 1469-1477 (2006).
    • (2006) Eur. J. Neurosci. , vol.21 , pp. 1469-1477
    • Smirnova, L.1
  • 56
    • 0031767514 scopus 로고    scopus 로고
    • The K box, a conserved 3 UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts
    • Lai, E. C., Burks, C. & Posakony, J. W. The K box, a conserved 3 UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts. Development 125, 4077-4088 (1998).
    • (1998) Development , vol.125 , pp. 4077-4088
    • Lai, E.C.1    Burks, C.2    Posakony, J.W.3
  • 57
    • 33644779735 scopus 로고    scopus 로고
    • The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation
    • Naguibneva, I. et al. The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation. Nature Cell Biol. 8, 278-284 (2006).
    • (2006) Nature Cell Biol. , vol.8 , pp. 278-284
    • Naguibneva, I.1
  • 58
    • 0033932628 scopus 로고    scopus 로고
    • Progressive restriction in fate potential by neural progenitors during cerebral cortical development
    • Desai, A. R. & McConnell, S. K. Progressive restriction in fate potential by neural progenitors during cerebral cortical development. Development 127, 2863-2872 (2000).
    • (2000) Development , vol.127 , pp. 2863-2872
    • Desai, A.R.1    McConnell, S.K.2
  • 59
    • 0035977135 scopus 로고    scopus 로고
    • Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes
    • Blackshaw, S. et al. Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes. Cell 107, 579-589 (2001).
    • (2001) Cell , vol.107 , pp. 579-589
    • Blackshaw, S.1
  • 60
    • 0037693842 scopus 로고    scopus 로고
    • The C. elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target
    • Lin, S. Y. et al. The C. elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target. Dev. Cell 4, 639-650 (2003).
    • (2003) Dev. Cell , vol.4 , pp. 639-650
    • Lin, S.Y.1
  • 61
    • 0024537378 scopus 로고
    • The Drosophila posterior-group gene nanos functions by repressing hunchback activity
    • Irish, V., Lehmann, R. & Akam, M. The Drosophila posterior-group gene nanos functions by repressing hunchback activity. Nature 338, 646-648 (1989).
    • (1989) Nature , vol.338 , pp. 646-648
    • Irish, V.1    Lehmann, R.2    Akam, M.3
  • 62
    • 8444235080 scopus 로고    scopus 로고
    • Specification of temporal identity in the developing nervous system
    • Pearson, B. J. & Doe, C. Q. Specification of temporal identity in the developing nervous system. Annu. Rev. Cell Dev. Biol. 20, 619-647 (2004).
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 619-647
    • Pearson, B.J.1    Doe, C.Q.2
  • 63
    • 32644434471 scopus 로고    scopus 로고
    • Regulation of neuroblast competence: Multiple temporal identity factors specify distinct neuronal fates within a single early competence window
    • Cleary, M. D. & Doe, C. Q. Regulation of neuroblast competence: multiple temporal identity factors specify distinct neuronal fates within a single early competence window. Genes Dev. 20, 429-434 (2006).
    • (2006) Genes Dev. , vol.20 , pp. 429-434
    • Cleary, M.D.1    Doe, C.Q.2
  • 64
    • 33745007605 scopus 로고    scopus 로고
    • Functional and selective RNA interference in developing axons and growth cones
    • Hengst, U. et al. Functional and selective RNA interference in developing axons and growth cones. J. Neurosci. 26, 5727-5732 (2006).
    • (2006) J. Neurosci. , vol.26 , pp. 5727-5732
    • Hengst, U.1
  • 65
    • 0035924590 scopus 로고    scopus 로고
    • Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation
    • Campbell, D. S. & Holt, C. E. Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation. Neuron 32, 1013-1026 (2001).
    • (2001) Neuron , vol.32 , pp. 1013-1026
    • Campbell, D.S.1    Holt, C.E.2
  • 66
    • 23944433636 scopus 로고    scopus 로고
    • Local translation of RhoA regulates growth cone collapse
    • Wu, K. Y. et al. Local translation of RhoA regulates growth cone collapse. Nature 436, 1020-1024 (2005).
    • (2005) Nature , vol.436 , pp. 1020-1024
    • Wu, K.Y.1
  • 67
    • 33751239360 scopus 로고    scopus 로고
    • Regulation of local protein translation in axons and growth cones by microRNAs
    • 617. 9/B5
    • Deglincerti, A., Hengst, U. & Jaffrey, S. R. Regulation of local protein translation in axons and growth cones by microRNAs. Soc. Neurosci. Abstr. 617. 9/B5 (2006).
    • (2006) Soc. Neurosci. Abstr.
    • Deglincerti, A.1    Hengst, U.2    Jaffrey, S.R.3
  • 68
    • 10944222754 scopus 로고    scopus 로고
    • Role of programmed cell death in normal neuronal development and function
    • Buss, R. R. & Oppenheim, R. W. Role of programmed cell death in normal neuronal development and function. Anat. Sci. Int. 79, 191-197 (2004).
    • (2004) Anat. Sci. Int. , vol.79 , pp. 191-197
    • Buss, R.R.1    Oppenheim, R.W.2
  • 69
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan, J. A., Krichevsky, A. M. & Kosik, K. S. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 65, 6029-6033 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 70
    • 23344439006 scopus 로고    scopus 로고
    • The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb
    • Harfe, B. D. et al. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc. Natl Acad. Sci. USA 102, 10898-10903 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 10898-10903
    • Harfe, B.D.1
  • 72
    • 0031024891 scopus 로고    scopus 로고
    • Synaptic tagging and long-term potentiation
    • Frey, U. & Morris, R. G. Synaptic tagging and long-term potentiation. Nature 385, 533-536 (1997).
    • (1997) Nature , vol.385 , pp. 533-536
    • Frey, U.1    Morris, R.G.2
  • 73
    • 0030799633 scopus 로고    scopus 로고
    • Brief theta-burst stimulation induces a transcription-dependent late phase of LTP requiring cAMP in area CA1 of the mouse hippocampus
    • Nguyen, P. V. & Kandel, E. R. Brief theta-burst stimulation induces a transcription-dependent late phase of LTP requiring cAMP in area CA1 of the mouse hippocampus. Learn. Mem. 4, 230-243 (1997).
    • (1997) Learn. Mem. , vol.4 , pp. 230-243
    • Nguyen, P.V.1    Kandel, E.R.2
  • 74
    • 0022835911 scopus 로고
    • A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia
    • Montarolo, P. G. et al. A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia. Science 234, 1249-1254 (1986).
    • (1986) Science , vol.234 , pp. 1249-1254
    • Montarolo, P.G.1
  • 75
    • 0021523971 scopus 로고
    • Protein synthesis and memory: A review
    • Davis, H. P. & Squire, L. R. Protein synthesis and memory: a review. Psychol. Bull. 96, 518-559 (1984).
    • (1984) Psychol. Bull. , vol.96 , pp. 518-559
    • Davis, H.P.1    Squire, L.R.2
  • 76
    • 0034990497 scopus 로고    scopus 로고
    • Dynamic visualization of local protein synthesis in hippocampal neurons
    • Aakalu, G. et al. Dynamic visualization of local protein synthesis in hippocampal neurons. Neuron 30, 489-502 (2001). Set up the rationale for performing experiments that sought a role for miRNAs in local dendritic translation.
    • (2001) Neuron , vol.30 , pp. 489-502
    • Aakalu, G.1
  • 77
    • 18744425893 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II mRNA association to polysomes
    • 2+/calmodulin-dependent protein kinase II mRNA association to polysomes. J. Neurosci. 20, RC76 (2000).
    • (2000) J. Neurosci. , vol.20
    • Bagni, C.1
  • 78
    • 0345528532 scopus 로고    scopus 로고
    • Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
    • Weiler, I. J. et al. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. Proc. Natl Acad. Sci. USA 94, 5395-5400 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5395-5400
    • Weiler, I.J.1
  • 79
    • 0029794770 scopus 로고    scopus 로고
    • A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity
    • Kang, H. & Schuman, E. M. A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. Science 273, 1402-1406 (1996).
    • (1996) Science , vol.273 , pp. 1402-1406
    • Kang, H.1    Schuman, E.M.2
  • 80
    • 0034942216 scopus 로고    scopus 로고
    • Chemical induction of mGluR5- and protein synthesis-dependent long-term depression in hippocampal area CA1
    • Huber, K. M., Roder, J. C. & Bear, M. F. Chemical induction of mGluR5- and protein synthesis-dependent long-term depression in hippocampal area CA1. J. Neurophysiol. 86, 321-325 (2001).
    • (2001) J. Neurophysiol. , vol.86 , pp. 321-325
    • Huber, K.M.1    Roder, J.C.2    Bear, M.F.3
  • 81
    • 0034685813 scopus 로고    scopus 로고
    • Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression
    • Huber, K. M., Kayser, M. S. & Bear, M. F. Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression. Science 288, 1254-1257 (2000).
    • (2000) Science , vol.288 , pp. 1254-1257
    • Huber, K.M.1    Kayser, M.S.2    Bear, M.F.3
  • 82
    • 31144479591 scopus 로고    scopus 로고
    • A brain-specific microRNA regulates dendritic spine development
    • Schratt, G. M. et al. A brain-specific microRNA regulates dendritic spine development. Nature 439, 283-289 (2006). The strongest suggestion so far that miRNAs are important regulators of plasticity.
    • (2006) Nature , vol.439 , pp. 283-289
    • Schratt, G.M.1
  • 83
    • 0033572284 scopus 로고    scopus 로고
    • The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
    • Olsen, P. H. & Ambros, V. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev. Biol. 216, 671-680 (1999).
    • (1999) Dev. Biol. , vol.216 , pp. 671-680
    • Olsen, P.H.1    Ambros, V.2
  • 84
    • 0035923735 scopus 로고    scopus 로고
    • Neuronal RNA granules: A link between RNA localization and stimulation-dependent translation
    • Krichevsky, A. M. & Kosik, K. S. Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation. Neuron 32, 683-696 (2001).
    • (2001) Neuron , vol.32 , pp. 683-696
    • Krichevsky, A.M.1    Kosik, K.S.2
  • 85
    • 0035956879 scopus 로고    scopus 로고
    • Internal initiation of translation of five dendritically localized neuronal mRNAs
    • Pinkstaff, J. K. et al. Internal initiation of translation of five dendritically localized neuronal mRNAs. Proc. Natl Acad. Sci. USA 98, 2770-2775 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2770-2775
    • Pinkstaff, J.K.1
  • 86
    • 30344449514 scopus 로고    scopus 로고
    • Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila
    • Ashraf, S. I. et al. Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. Cell 124, 191-205 (2006). A paper that will grow in importance not only for its insights regarding miRNA regulation as a function of synaptic activity, but the potential of the approach to reveal a molecular-level image of brain activity.
    • (2006) Cell , vol.124 , pp. 191-205
    • Ashraf, S.I.1
  • 87
    • 0034927379 scopus 로고    scopus 로고
    • Protein synthesis at synaptic sites on dendrites
    • Steward, O. & Schuman, E. M. Protein synthesis at synaptic sites on dendrites. Annu. Rev. Neurosci. 24, 299-325 (2001).
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 299-325
    • Steward, O.1    Schuman, E.M.2
  • 88
    • 33644584429 scopus 로고    scopus 로고
    • Dendritic mRNAs encode diversified functionalities in hippocampal pyramidal neurons
    • Zhong, J., Zhang, T. & Bloch, L. M. Dendritic mRNAs encode diversified functionalities in hippocampal pyramidal neurons. BMC Neurosci. 7, 17 (2006).
    • (2006) BMC Neurosci. , vol.7 , pp. 17
    • Zhong, J.1    Zhang, T.2    Bloch, L.M.3
  • 89
    • 0345276563 scopus 로고    scopus 로고
    • Mechanisms of translational control in dendrites
    • Glanzer, J. G. & Eberwine, J. H. Mechanisms of translational control in dendrites. Neurobiol. Aging 24, 1105-1111 (2003).
    • (2003) Neurobiol. Aging , vol.24 , pp. 1105-1111
    • Glanzer, J.G.1    Eberwine, J.H.2
  • 90
    • 17144466355 scopus 로고    scopus 로고
    • Differential expression and dendritic transcript localization of Shank family members: Identification of a dendritic targeting element in the 3′ untranslated region of Shank1 mRNA
    • Bockers, T. M. et al. Differential expression and dendritic transcript localization of Shank family members: identification of a dendritic targeting element in the 3′ untranslated region of Shank1 mRNA. Mol. Cell. Neurosci. 26, 182-190 (2004).
    • (2004) Mol. Cell. Neurosci. , vol.26 , pp. 182-190
    • Bockers, T.M.1
  • 91
    • 0033570305 scopus 로고    scopus 로고
    • Identification of a cis-acting dendritic targeting element in MAP2 mRNAs
    • Blichenberg, A. et al. Identification of a cis-acting dendritic targeting element in MAP2 mRNAs. J. Neurosci. 19, 8818-8829 (1999).
    • (1999) J. Neurosci. , vol.19 , pp. 8818-8829
    • Blichenberg, A.1
  • 92
    • 0029844105 scopus 로고    scopus 로고
    • The 3′-untranslated region of CaMKIIa is a cis-acting signal for the localization and translation of mRNA in dendrites
    • Mayford, M. et al. The 3′-untranslated region of CaMKIIa is a cis-acting signal for the localization and translation of mRNA in dendrites. Proc. Natl Acad. Sci. USA 93, 13250-13255 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13250-13255
    • Mayford, M.1
  • 93
    • 0343090204 scopus 로고    scopus 로고
    • Molecular characterization of dendritically localized transcripts encoding MAP2
    • Kindler, S. et al. Molecular characterization of dendritically localized transcripts encoding MAP2. Brain Res. Mol. Brain Res. 36, 63-69 (1996).
    • (1996) Brain Res. Mol. Brain Res. , vol.36 , pp. 63-69
    • Kindler, S.1
  • 94
    • 0033769356 scopus 로고    scopus 로고
    • Two cis-acting elements in the 3′ untranslated region of α-CaMKII regulate its dendritic targeting
    • Mori, Y. et al. Two cis-acting elements in the 3′ untranslated region of α-CaMKII regulate its dendritic targeting. Nature Neurosci. 3, 1079-1084 (2000).
    • (2000) Nature Neurosci. , vol.3 , pp. 1079-1084
    • Mori, Y.1
  • 95
    • 23844501276 scopus 로고    scopus 로고
    • Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner
    • Lugli, G. et al. Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner. J. Neurochem. 94, 896-905 (2005).
    • (2005) J. Neurochem. , vol.94 , pp. 896-905
    • Lugli, G.1
  • 96
    • 0035036344 scopus 로고    scopus 로고
    • Selective targeting of newly synthesized arc mRNA to active synapses requires NMDA receptor activation
    • Steward, O. & Worley, P. F. Selective targeting of newly synthesized arc mRNA to active synapses requires NMDA receptor activation. Neuron 30, 227-240 (2001).
    • (2001) Neuron , vol.30 , pp. 227-240
    • Steward, O.1    Worley, P.F.2
  • 97
    • 0032191909 scopus 로고    scopus 로고
    • Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites
    • Steward, O. et al. Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21, 741-751 (1998).
    • (1998) Neuron , vol.21 , pp. 741-751
    • Steward, O.1
  • 98
    • 1642540373 scopus 로고    scopus 로고
    • Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
    • Jin, P. et al. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nature Neurosci. 7, 113-117 (1998).
    • (1998) Nature Neurosci. , vol.7 , pp. 113-117
    • Jin, P.1
  • 99
    • 28044439909 scopus 로고    scopus 로고
    • A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis
    • Vo, N. et al. A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc. Natl Acad. Sci. USA 102, 16426-16431 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 16426-16431
    • Vo, N.1
  • 100
    • 0032195577 scopus 로고    scopus 로고
    • Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning
    • Impey, S. et al. Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning. Nature Neurosci. 1, 595-601 (1998).
    • (1998) Nature Neurosci. , vol.1 , pp. 595-601
    • Impey, S.1
  • 101
    • 0037456560 scopus 로고    scopus 로고
    • Sunrise at the synapse: The FMRP mRNP shaping the synaptic interface
    • Antar, L. N. & Bassell, G. J. Sunrise at the synapse: the FMRP mRNP shaping the synaptic interface. Neuron 37, 555-558 (2003).
    • (2003) Neuron , vol.37 , pp. 555-558
    • Antar, L.N.1    Bassell, G.J.2
  • 102
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - MicroRNAs with a role in cancer
    • Esquela-Kerscher, A. & Slack, F. J. Oncomirs - microRNAs with a role in cancer. Nature Rev. Cancer 6, 259-269 (2006). An excellent overview, among the several that have been written, on the emerging relationship between miRNAs and cancer.
    • (2006) Nature Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 103
    • 33745168962 scopus 로고    scopus 로고
    • MicroRNAs exhibit high frequency genomic alterations in human cancer
    • Zhang, L. et al. microRNAs exhibit high frequency genomic alterations in human cancer. Proc. Natl Acad. Sci. USA 103, 9136-9141 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 9136-9141
    • Zhang, L.1
  • 104
    • 33745577150 scopus 로고    scopus 로고
    • A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep
    • Clop, A. et al. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nature Genet. 38, 813-818 (2006). This paper is the leading edge of what will emerge as a windfall of genetic data related to polymorphisms at miRNA target sites with functional consequences.
    • (2006) Nature Genet. , vol.38 , pp. 813-818
    • Clop, A.1
  • 105
    • 26844498125 scopus 로고    scopus 로고
    • Sequence variants in SLITRK1 are associated with Tourette's syndrome
    • Abelson, J. F. et al. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science 310, 317-320 (2005). Presents a novel and provocative basis for a poorly understood syndrome.
    • (2005) Science , vol.310 , pp. 317-320
    • Abelson, J.F.1
  • 106
    • 0037447334 scopus 로고    scopus 로고
    • The microRNAs of Caenorhabditis elegans
    • Lim, L. P. et al. The microRNAs of Caenorhabditis elegans. Genes Dev. 17, 991-1008 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 991-1008
    • Lim, L.P.1
  • 107
    • 33144481470 scopus 로고    scopus 로고
    • Reciprocal actions of REST and a microRNA promote neuronal identity
    • Conaco, C. et al. Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl Acad. Sci. USA 103, 2422-2427 (2006). Opens the way to a network approach to the acquisition and maintenance of cell identity.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2422-2427
    • Conaco, C.1
  • 108
    • 33745299723 scopus 로고    scopus 로고
    • Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
    • Grimm, D. et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 441, 537-541 (2006). An important cautionary note.
    • (2006) Nature , vol.441 , pp. 537-541
    • Grimm, D.1


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