Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2

Cell

Volumn 129, Issue 2, 2007, Pages 303-317

  Zhao, Yong ^a,b,c   Ransom, Joshua F ^a,b,c   Li, Ankang ^d   Vedantham, Vasanth ^a,b   von Drehle, Morgan ^a   Muth, Alecia N ^a   Tsuchihashi, Takatoshi ^a,b,c   McManus, Michael T ^b   Schwartz, Robert J ^d   Srivastava, Deepak ^a,b,c  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 1; MICRORNA 2; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; BINDING SITE; BIOGENESIS; CELL CYCLE ARREST; CELL CYCLE REGULATION; CONTROLLED STUDY; ELECTRIC CONDUCTIVITY; EMBRYO; GENE DELETION; GENE SEQUENCE; HEART FUNCTION; HEART MUSCLE CONDUCTION DISTURBANCE; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

MAMMALIA; MUS;

EID: 34147153781     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2007.03.030     Document Type: Article

References (69)

1. Ambros V. The functions of animal microRNAs. Nature 431 (2004) 350-355
2. Berezikov E., Thuemmler F., van Laake L.W., Kondova I., Bontrop R., Cuppen E., and Plasterk R.H. Diversity of microRNAs in human and chimpanzee brain. Nat. Genet. 38 (2006) 1375-1377
3. Bernstein E., Caudy A.A., Hammond S.M., and Hannon G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409 (2001) 363-366
4. Birmingham A., Anderson E.M., Reynolds A., Ilsley-Tyree D., Leake D., Fedorov Y., Baskerville S., Maksimova E., Robinson K., Karpilow J., et al. 3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat. Methods 3 (2006) 199-204
5. Brennecke J., Hipfner D.R., Stark A., Russell R.B., and Cohen S.M. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113 (2003) 25-36
6. Brennecke J., Stark A., Russell R.B., and Cohen S.M. Principles of microRNA-target recognition. PLoS Biol. 3 (2005) e85
7. Buckingham M., Meilhac S., and Zaffran S. Building the mammalian heart from two sources of myocardial cells. Nat. Rev. Genet. 6 (2005) 826-835
8. Chen J.F., Mandel E.M., Thomson J.M., Wu Q., Callis T.E., Hammond S.M., Conlon F.L., and Wang D.Z. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat. Genet. 38 (2006) 228-233
9. Cheng C.F., Kuo H.C., and Chien K.R. Genetic modifiers of cardiac arrhythmias. Trends Mol. Med. 9 (2003) 59-66
10. Cohen S.M., Brennecke J., and Stark A. Denoising feedback loops by thresholding-a new role for microRNAs. Genes Dev. 20 (2006) 2769-2772
11. Costantini D.L., Arruda E.P., Agarwal P., Kim K.-H., Zhu Y., Lebel M., Cheng C.W., Park C.Y., Pierce S., Guerchicoff A., et al. The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell 123 (2005) 347-358
12. Desai A.D., Yaw T.S., Yamazaki T., Kaykha A., Chun S., and Froelicher V.F. Prognostic Significance of Quantitative QRS Duration. Am. J. Med. 119 (2006) 600-606
13. Didiano D., and Hobert O. Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions. Nat. Struct. Mol. Biol. 13 (2006) 849-851
14. Du T., and Zamore P.D. microPrimer: The biogenesis and function of microRNA. Development 132 (2005) 4645-4652
15. Fischer A., and Gessler M. Hey genes in cardiovascular development. Trends Cardiovasc. Med. 13 (2003) 221-226
16. Garg V., Kathiriya I.S., Barnes R., Schluterman M.K., King I.N., Butler C.A., Rothrock C.R., Eapen R.S., Hirayama-Yamada K., Joo K., et al. GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature 424 (2003) 443-447
17. Garg V., Muth A.N., Ransom J.F., Schluterman M.K., Barnes R., King I.N., Grossfeld P.D., and Srivastava D. Mutations in NOTCH1 cause aortic valve disease. Nature 437 (2005) 270-274
18. Gottlieb P.D., Pierce S.A., Sims R.J., Yamagishi H., Weihe E.K., Harriss J.V., Maika S.D., Kuziel W.A., King H.L., Olson E.N., et al. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat. Genet. 31 (2002) 25-32
19. Gourdie R.G., Kubalak S., and Mikawa T. Conducting the embryonic heart: Orchestrating development of specialized cardiac tissues. Trends Cardiovasc. Med. 9 (1999) 18-26
20. Harfe B.D., McManus M.T., Mansfield J.H., Hornstein E., and Tabin C.J. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc. Natl. Acad. Sci. USA 102 (2005) 10898-10903
21. Hoffman J.I., Kaplan S., and Liberthson R.R. Prevalence of congenital heart disease. Am. Heart J. 147 (2004) 425-439
22. Hornstein E., Mansfield J.H., Yekta S., Hu J.K., Harfe B.D., McManus M.T., Baskerville S., Bartel D.P., and Tabin C.J. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature 438 (2005) 671-674
23. Jackson A.L., Burchard J., Schelter J., Chau B.N., Cleary M., Lim L., and Linsley P.S. Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity. RNA 12 (2006) 1179-1187
24. Johnston R.J., and Hobert O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature 426 (2003) 845-849
25. Kim H.K., Lee Y.S., Sivaprasad U., Malhotra A., and Dutta A. Muscle-specific microRNA miR-206 promotes muscle differentiation. J. Cell Biol. 174 (2006) 677-687
26. Kloosterman W.P., and Plasterk R.H. The diverse functions of microRNAs in animal development and disease. Dev. Cell 11 (2006) 441-450
27. Koo B.-K., Lim H.-S., Song R., Yoon M.-J., Yoon K.-J., Moon J.-S., Kim Y.-W., Kwon M.-C., Yoo K.-W., Kong M.-P., et al. Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development 132 (2005) 3459-3470
28. Kwon C., Han Z., Olson E.N., and Srivastava D. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc. Natl. Acad. Sci. USA 102 (2005) 18986-18991
29. Lagos-Quintana M., Rauhut R., Lendeckel W., and Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 294 (2001) 853-858
30. Lee R.C., Feinbaum R.L., and Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75 (1993) 843-854
31. Lewis B.P., Burge C.B., and Bartel D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120 (2005) 15-20
32. Li F., Wang X., Capasso J.M., and Gerdes A.M. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J. Mol. Cell. Cardiol. 28 (1996) 1737-1746
33. Liao J., Kochilas L., Nowotschin S., Arnold J.S., Aggarwal V.S., Epstein J.A., Brown M.C., Adams J., and Morrow B.E. Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage. Hum. Mol. Genet. 13 (2004) 1577-1585
34. Lim L.P., Lau N.C., Garrett-Engele P., Grimson A., Schelter J.M., Castle J., Bartel D.P., Linsley P.S., and Johnson J.M. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433 (2005) 769-773
35. MacLellan W.R., and Schneider M.D. Genetic dissection of cardiac growth control pathways. Annu. Rev. Physiol. 62 (2000) 289-319
36. McFadden D.G., Barbosa A.C., Richardson J.A., Schneider M.D., Srivastava D., and Olson E.N. The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development 132 (2005) 189-201
37. Moses K.A., DeMayo F., Braun R.M., Reecy J.L., and Schwartz R.J. Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice. Genesis 31 (2001) 176-180
38. Moss E.G., Lee R.C., and Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 88 (1997) 637-646
39. Nakagawa O., Nakagawa M., Richardson J.A., Olson E.N., and Srivastava D. HRT1, HRT2, and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev. Biol. 216 (1999) 72-84
40. Olson E.N. Gene regulatory networks in the evolution and development of the heart. Science 313 (2006) 1922-1927
41. Rajewsky N. microRNA target predictions in animals. Nat. Genet. 38 Suppl (2006) S8-S13
42. Rao P.K., Kumar R.M., Farkhondeh M., Baskerville S., and Lodish H.F. Myogenic factors that regulate expression of muscle-specific microRNAs. Proc. Natl. Acad. Sci. USA (2006) in press
43. Redon R., Ishikawa S., Fitch K.R., Feuk L., Perry G.H., Andrews T.D., Fiegler H., Shapero M.H., Carson A.R., Chen W., et al. Global variation in copy number in the human genome. Nature 444 (2006) 444-454
44. Reinhart B.J., Slack F.J., Basson M., Pasquinelli A.E., Bettinger J.C., Rougvie A.E., Horvitz H.R., and Ruvkun G. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403 (2000) 901-906
45. Sayed D., Hong C., Chen I.Y., Lypowy J., and Abdellatif M. MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ. Res. 100 (2007) 416-424
46. Shin C.H., Liu Z.P., Passier R., Zhang C.L., Wang D.Z., Harris T.M., Yamagishi H., Richardson J.A., Childs G., and Olson E.N. Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell 110 (2002) 725-735
47. Sokol N.S., and Ambros V. Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth. Genes Dev. 19 (2005) 2343-2354
48. Soonpaa M.H., and Field L.J. Survey of studies examining mammalian cardiomyocyte DNA synthesis. Circ. Res. 83 (1998) 15-26
49. Srivastava D. Making or breaking the heart: From lineage determination to morphogenesis. Cell 126 (2006) 1037-1048
50. Srivastava D., Cserjesi P., and Olson E.N. A subclass of bHLH proteins required for cardiac morphogenesis. Science 270 (1995) 1995-1999
51. Srivastava D., Thomas T., Lin Q., Kirby M.L., Brown D., and Olson E.N. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat. Genet. 16 (1997) 154-160
52. Stark A., Brennecke J., Russell R.B., and Cohen S.M. Identification of Drosophila MicroRNA targets. PLoS Biol. 1 (2003) E60
53. Thom T., Haase N., Rosamond W., Howard V.J., Rumsfeld J., Manolio T., Zheng Z.J., Flegal K., O'Donnell C., Kittner S., et al. Heart disease and stroke statistics-2006 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 113 (2006) e85-e151
54. Torella D., Ellison G.M., Mendez-Ferrer S., Ibanez B., and Nadal-Ginard B. Resident human cardiac stem cells: role in cardiac cellular homeostasis and potential for myocardial regeneration. Nat. Clin. Pract. Cardiovasc. Med. 3 (2006) S83-S89
55. Valencia-Sanchez M.A., Liu J., Hannon G.J., and Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev. 20 (2006) 515-524
56. van Rooij E., Sutherland L.B., Liu N., Williams A.H., McAnally J., Gerard R.D., Richardson J.A., and Olson E.N. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc. Natl. Acad. Sci. USA 103 (2006) 18255-18260
57. Vella M.C., Choi E.Y., Lin S.Y., Reinert K., and Slack F.J. The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR. Genes Dev. 18 (2004) 132-137
58. Wei Y., Mizzen C.A., Cook R.G., Gorovsky M.A., and Allis C.D. Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena. Proc. Natl. Acad. Sci. USA 95 (1998) 7480-7484
59. Wienholds E., Kloosterman W.P., Miska E., Alvarez-Saavedra E., Berezikov E., de Bruijn E., Horvitz H.R., Kauppinen S., and Plasterk R.H. MicroRNA expression in zebrafish embryonic development. Science 309 (2005) 310-311
60. Wightman B., Ha I., and Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75 (1993) 855-862
61. Xie X., Lu J., Kulbokas E.J., Golub T.R., Mootha V., Lindblad-Toh K., Lander E.S., and Kellis M. Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals. Nature 434 (2005) 338-345
62. Xin M., Davis C.A., Molkentin J.D., Lien C.L., Duncan S.A., Richardson J.A., and Olson E.N. A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proc. Natl. Acad. Sci. USA 103 (2006) 11189-11194
63. Yamagishi H., Yamagishi C., Nakagawa O., Harvey R.P., Olson E.N., and Srivastava D. The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev. Biol. 239 (2001) 190-203
64. Yamagishi H., Maeda J., Hu T., McAnally J., Conway S.J., Kume T., Meyers E.N., Yamagishi C., and Srivastava D. Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev. 17 (2003) 269-281
65. Yelon D., Ticho B., Halpern M.E., Ruvinsky I., Ho R.K., Silver L.M., and Stainier D.Y. The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin development. Development 127 (2000) 2573-2582
66. Yi R., O'Carroll D., Pasolli H.A., Zhang Z., Dietrich F.S., Tarakhovsky A., and Fuchs E. Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat. Genet. 38 (2006) 356-362
67. Zhao Y., Samal E., and Srivastava D. Serum response factor regulates a muscle-specific mircroRNA that targets Hand2 during cardiogenesis. Nature 436 (2005) 214-220
68. Zhao Y., and Srivastava D. A developmental view of microRNA function. Trends Biochem. Sci. (2007) 10.1016/j.tibs.2007.1002.1006 in press. Published online March 8, 2007
69. Zipes D.P., and Wellens H.J. Sudden cardiac death. Circulation 98 (1998) 2334-2351