Cholesterol and Alzheimer's disease: Clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors

Current Drug Targets

Volumn 5, Issue 6, 2004, Pages 517-528

  Sambamurti, Kumar ^a   Granholm, Ann Charlotte ^a   Kindy, Mark S ^a,e   Bhat, Narayan R ^a   Greig, Nigel H ^b   Lahiri, Debomoy K ^c   Mintzer, Jacobo E ^d,e  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Center on Aging   (United States)

^e RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

Aging; Apolipoprotein E; Cognition; Dementia; Diets; High fats; Memory; Myelin; Secretase

Indexed keywords

4 [2 [1 (4 CHLOROCINNAMYL) 4 PIPERAZINYL]ETHYL]BENZOIC ACID; ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; ANDROGEN; APOLIPOPROTEIN E; APOLIPOPROTEIN E4; BETA SECRETASE; CHOLESTEROL; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; ESTROGEN; GAMMA SECRETASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; LIPID; METHYL BETA CYCLODEXTRIN; MEVINOLIN; MITOGEN ACTIVATED PROTEIN KINASE; PRESENILIN 1; PRESENILIN 2; PROTEIN PRECURSOR; TAU PROTEIN; TESTOSTERONE;

ALLELE; ALZHEIMER DISEASE; ANDROGEN THERAPY; BIOCHEMISTRY; CARDIOVASCULAR RISK; CHOLESTEROL DIET; DIETARY INTAKE; ESTROGEN THERAPY; ETHNIC DIFFERENCE; GENE IDENTIFICATION; GENETIC RISK; HUMAN; LIPID DIET; MENOPAUSAL SYNDROME; MOLECULAR BIOLOGY; MUTATIONAL ANALYSIS; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PAIRED HELICAL FILAMENT; PATHOGENESIS; PROTEIN FUNCTION; RACE DIFFERENCE; REVIEW; RISK FACTOR; SENILE DEMENTIA; SENILE PLAQUE;

ALZHEIMER DISEASE; ANIMALS; CELLS, CULTURED; CHOLESTEROL; CLINICAL TRIALS; DIET; DISEASE MODELS, ANIMAL; ENVIRONMENTAL EXPOSURE; HUMANS; RISK FACTORS;

EID: 3442878151     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450043345335     Document Type: Review

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