-
1
-
-
0032211830
-
The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease
-
Selkoe, D.J. The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol. 8, 447-453 (1998).
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
2
-
-
0031958152
-
Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease
-
Cotman, C.W. Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease. Neurobiol. Aging 18, S29-S32 (1998).
-
(1998)
Neurobiol. Aging
, vol.18
-
-
Cotman, C.W.1
-
3
-
-
0028981717
-
The Alzheimer's A β peptide induces neurodegeneration and apoptotic cell death in transgenic mice
-
LaFerla, F.M., Tinkle, B.T., Bieberich, C.J., Haudenschild, C.C. & Jay, G. The Alzheimer's A β peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nature Genet. 9, 21-30 (1995).
-
(1995)
Nature Genet.
, vol.9
, pp. 21-30
-
-
LaFerla, F.M.1
Tinkle, B.T.2
Bieberich, C.J.3
Haudenschild, C.C.4
Jay, G.5
-
4
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimer's disease
-
Yankner, B.A. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron 16, 921-932 (1996).
-
(1996)
Neuron
, vol.16
, pp. 921-932
-
-
Yankner, B.A.1
-
6
-
-
0032558787
-
The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis
-
Mehlen, P. et al. The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis. Nature 395, 801-804 (1998).
-
(1998)
Nature
, vol.395
, pp. 801-804
-
-
Mehlen, P.1
-
7
-
-
0027324122
-
Induction of apoptosis by the low-affinity NGF receptor
-
Rabizadeh, S. et al. Induction of apoptosis by the low-affinity NGF receptor. Science 261, 345-348 (1993).
-
(1993)
Science
, vol.261
, pp. 345-348
-
-
Rabizadeh, S.1
-
8
-
-
0032146775
-
Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons
-
Barnes, N.Y. et al. Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons. J. Neurosci. 18, 5869-5880 (1996).
-
(1996)
J. Neurosci.
, vol.18
, pp. 5869-5880
-
-
Barnes, N.Y.1
-
9
-
-
0033605252
-
Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases
-
Weidemann, A. et al. Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases. J. Biol. Chem. 274, 5823-5829 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5823-5829
-
-
Weidemann, A.1
-
10
-
-
0033617402
-
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-β precursor protein and amyloidogenic Aβ peptide formation
-
Gervais, F.G. et al. Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-β precursor protein and amyloidogenic Aβ peptide formation. Cell 97, 395-406 (1999).
-
(1999)
Cell
, vol.97
, pp. 395-406
-
-
Gervais, F.G.1
-
11
-
-
0033597884
-
Alternative, non-secretase processing of Alzheimer's β-amyloid precursor protein during apoptosis by caspase-6 and-8
-
Pellegrini, L., Passer, B.J., Tabaton, M., Ganjei, J.K. & D'Adamio, L. Alternative, non-secretase processing of Alzheimer's β-amyloid precursor protein during apoptosis by caspase-6 and-8. J. Biol. Chem. 274, 21011-21016 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21011-21016
-
-
Pellegrini, L.1
Passer, B.J.2
Tabaton, M.3
Ganjei, J.K.4
D'Adamio, L.5
-
12
-
-
0033551738
-
Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease
-
LeBianc, A., Liu, H., Goodyer, C., Bergeron, C. & Hammond, J. Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease. J. Biol. Chem. 274, 23426-23436 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23426-23436
-
-
LeBianc, A.1
Liu, H.2
Goodyer, C.3
Bergeron, C.4
Hammond, J.5
-
13
-
-
0029862137
-
Age-dependent neuronal and synaptic degeneration in mice transgenic for the c terminus of the amyloid precursor protein
-
Oster-Granite, M.L., McPhie, D.L., Greenan, J. & Neve, R.L. Age-dependent neuronal and synaptic degeneration in mice transgenic for the c terminus of the amyloid precursor protein. J. Neurosci. 16, 6732-6741 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 6732-6741
-
-
Oster-Granite, M.L.1
McPhie, D.L.2
Greenan, J.3
Neve, R.L.4
-
14
-
-
0024472693
-
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease
-
Yankner, B.A. et al. Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. Science 245, 417-420 (1989).
-
(1989)
Science
, vol.245
, pp. 417-420
-
-
Yankner, B.A.1
-
15
-
-
0027300915
-
Selective neurotoxicity of COOH-terminal fragments of the beta-amyloid precursor protein
-
Fukuchi, K. et al. Selective neurotoxicity of COOH-terminal fragments of the beta-amyloid precursor protein. Neurosci. Lett. 154, 145-148 (1992).
-
(1992)
Neurosci. Lett.
, vol.154
, pp. 145-148
-
-
Fukuchi, K.1
-
16
-
-
0027971254
-
Cytotoxicity mediated by conditional expression of a carboxyl-terminal derivative of the beta-amyloid precursor protein
-
Sopher, B.L. et al. Cytotoxicity mediated by conditional expression of a carboxyl-terminal derivative of the beta-amyloid precursor protein. Mol. Brain Res. 26, 207-217 (1994).
-
(1994)
Mol. Brain Res.
, vol.26
, pp. 207-217
-
-
Sopher, B.L.1
-
17
-
-
0028351791
-
Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer β/A4 amyloid precursor protein
-
Caporaso, G.L. et al. Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer β/A4 amyloid precursor protein. J. Neurosci. 14, 3122-38 (1994).
-
(1994)
J. Neurosci.
, vol.14
, pp. 3122-3138
-
-
Caporaso, G.L.1
-
18
-
-
0031031006
-
Trafficking of cell-surface β-amyloid precursor protein, evidence that a sorting intermediate participates in synaptic vesicle recycling
-
Marquez-Sterling, N.R., Lo, A.C.Y., Sisodia, S.S. & Koo, E.H. Trafficking of cell-surface β-amyloid precursor protein, evidence that a sorting intermediate participates in synaptic vesicle recycling. J. Neurosci. 17, 140-151 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 140-151
-
-
Marquez-Sterling, N.R.1
Lo, A.C.Y.2
Sisodia, S.S.3
Koo, E.H.4
-
19
-
-
0032898311
-
Kennedy's disease, caspase cleavage of the androgen receptor is a crucial event in cytotoxicity
-
Ellerby, L.M. et al. Kennedy's disease, caspase cleavage of the androgen receptor is a crucial event in cytotoxicity. J. Neurochem. 72, 185-195 (1999).
-
(1999)
J. Neurochem.
, vol.72
, pp. 185-195
-
-
Ellerby, L.M.1
-
20
-
-
0027324122
-
Induction of apoptosis by the low-affinity NGF receptor
-
Rabizadeh, S. et al. Induction of apoptosis by the low-affinity NGF receptor. Science 261, 345-348 (1993).
-
(1993)
Science
, vol.261
, pp. 345-348
-
-
Rabizadeh, S.1
-
21
-
-
0030867815
-
Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a c-terminal fragment containing both the amyloid beta and cytoplasmic domains
-
McPhie, D.L. et al. Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a c-terminal fragment containing both the amyloid beta and cytoplasmic domains. J. Biol. Chem. 272, 24743-24746 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24743-24746
-
-
McPhie, D.L.1
-
22
-
-
0031596265
-
Mechanisms of synaptic pathology in Alzheimer's disease
-
Masliah, E. Mechanisms of synaptic pathology in Alzheimer's disease. J. Neural Trans. 53, 147-58 (1998).
-
(1998)
J. Neural Trans.
, vol.53
, pp. 147-158
-
-
Masliah, E.1
-
23
-
-
0031930313
-
Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease
-
Yang, F. et al. Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease. Am. J. Pathol. 152, 379-389 (1998).
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 379-389
-
-
Yang, F.1
-
24
-
-
0032487648
-
Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites
-
Mattson, M.P., Partin, J. & Begley, J.G. Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites. Brain Res. 807, 167-176 (1998).
-
(1998)
Brain Res.
, vol.807
, pp. 167-176
-
-
Mattson, M.P.1
Partin, J.2
Begley, J.G.3
-
25
-
-
0033179170
-
Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease
-
Chan, S.L., Griffin, W.S.T. & Mattson, M.P. Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease. J. Neurosci. Res. 57, 315-323 (1999).
-
(1999)
J. Neurosci. Res.
, vol.57
, pp. 315-323
-
-
Chan, S.L.1
Griffin, W.S.T.2
Mattson, M.P.3
-
26
-
-
0032747486
-
Activation of caspase-3 in single neurons and autophagic granules of granuolvacuolar degeneration in Alzheimer's disease
-
Stadelmann, C. et al. Activation of caspase-3 in single neurons and autophagic granules of granuolvacuolar degeneration in Alzheimer's disease. Am. J. Pathol. 155, 1459-66 (1999).
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1459-1466
-
-
Stadelmann, C.1
-
27
-
-
0032873466
-
In situ immunodetection of neuronal caspase-3 activation in Alzheimer's disease
-
Selznick, L.A. et al. In situ immunodetection of neuronal caspase-3 activation in Alzheimer's disease. J. Neuropathol. Exp. Neurol. 58, 1020-1026 (1999).
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 1020-1026
-
-
Selznick, L.A.1
-
28
-
-
0033551738
-
Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease
-
LeBlanc, A., Liu, H., Goodyer, C., Bergeron, C. & Hammond, J. Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease. J. Biol. Chem. 274, 23426-23436 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23426-23436
-
-
LeBlanc, A.1
Liu, H.2
Goodyer, C.3
Bergeron, C.4
Hammond, J.5
-
29
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen, G.S. & Dixit, V.M. Caspases: intracellular signaling by proteolysis. Cell 91, 443-446 (1997).
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
30
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry, N.A. & Lazebnik, Y. Caspases: enemies within. Science 281, 1312-1316 (1998).
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
31
-
-
15144345497
-
Pro-caspase-3 is a major physiologic target of caspase-8
-
Stennicke, H.R. et al. Pro-caspase-3 is a major physiologic target of caspase-8. J. Biol. Chem. 273, 27084-27090 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27084-27090
-
-
Stennicke, H.R.1
-
32
-
-
0027212769
-
Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system
-
Sisodia, S.S., Koo, E.H., Hoffman, P.N., Perry, G. & Price, D.L. Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system. J. Neurosci. 13, 3136-3142 (1993).
-
(1993)
J. Neurosci.
, vol.13
, pp. 3136-3142
-
-
Sisodia, S.S.1
Koo, E.H.2
Hoffman, P.N.3
Perry, G.4
Price, D.L.5
-
33
-
-
0028276801
-
Evidence that production and release of amyloid beta-protein involves the endocytic pathway
-
Koo, E.H. & Squazzo, S.L. Evidence that production and release of amyloid beta-protein involves the endocytic pathway. J. Biol. Chem. 269, 17386-17389 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
34
-
-
13044305983
-
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia
-
Krajewski, S. et al. Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia. Proc. Natl. Acad. Sci. USA 96, 5752-5757 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5752-5757
-
-
Krajewski, S.1
-
35
-
-
0033199115
-
Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation
-
Wolf, B.B. et al. Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation. Blood 94, 1683-1692 (1999).
-
(1999)
Blood
, vol.94
, pp. 1683-1692
-
-
Wolf, B.B.1
-
36
-
-
0030898680
-
Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice
-
Shindler, K.S., Latham, C.B. & Roth, K.A. Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice. J. Neurosci. 17, 3112-3119 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 3112-3119
-
-
Shindler, K.S.1
Latham, C.B.2
Roth, K.A.3
-
37
-
-
0032553422
-
A novel neuron-specific aminopeptidase in rat brain synaptosome. Its identification, purification, and characterization
-
Hui, K.S., Saito, M. & Hui, M. A novel neuron-specific aminopeptidase in rat brain synaptosome. Its identification, purification, and characterization. J. Biol. Chem. 273, 31053-31060 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31053-31060
-
-
Hui, K.S.1
Saito, M.2
Hui, M.3
|