Targeting APP metabolism for the treatment of Alzheimer's disease

Drug Development Research

Volumn 56, Issue 2, 2002, Pages 211-227

  Sambamurti, Kumar ^a   Hardy, John ^b   Refolo, Lorenzo M ^c   Lahiri, Debomoy K ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c Alzheimers Drug Discovery Foundation   (United States)

Author keywords

secretase; AICD; Alzheimer's disease; Amyloid peptide; Amyloid protein precursor; BACE; CTF ; CTF ; NICD; NSAIDS; Site APP cleaving enzyme; Statins

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ANTILIPEMIC AGENT; APOLIPOPROTEIN E; BETA AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME; BETA SECRETASE; CHOLESTEROL; GAMMA SECRETASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IBUPROFEN; MELATONIN; MEMBRANE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; CHOLESTEROL METABOLISM; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HYPERCHOLESTEROLEMIA; NEUROLOGIC DISEASE; NEUROTOXICITY; NONHUMAN; PROTEIN METABOLISM; REVIEW; VACCINATION;

EID: 0036594993     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10077     Document Type: Review

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