Constitutive and regulated α-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 7, 1999, Pages 3922-3927

  Lammich, Sven ^a   Kojro, Elzbieta ^a   Postina, Rolf ^a   Gilbert, Sandra ^a   Pfeiffer, Roland ^a   Jasionowski, Marek ^b   Haass, Christian ^c   Fahrenholz, Falk ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF GDA SK   (Poland)

^c CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; DISINTEGRIN; METALLOPROTEINASE; PROTEIN KINASE C;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; CELL MEMBRANE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GOLGI COMPLEX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION;

ADAM PROTEINS; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CATTLE; CELL LINE; CLONING, MOLECULAR; ENDOPEPTIDASES; HUMANS; KIDNEY; KINETICS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; POINT MUTATION; PROTEIN KINASE C; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TRANSFECTION; ZINC;

EID: 0033616716     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.7.3922     Document Type: Article

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