Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-β precursor protein and amyloidogenic Aβ peptide formation

Cell

Volumn 97, Issue 3, 1999, Pages 395-406

  Gervais, François G ^a   Xu, Daigen ^a   Robertson, George S ^a   Vaillancourt, John P ^a   Zhu, Yanxia ^a   Huang, JingQi ^a   LeBlanc, Andréa ^e   Smith, David ^b   Rigby, Michael ^b   Shearman, Mark S ^b   Clarke, Earl E ^b   Zheng, Hui ^c   Van Der Ploeg, Leonardus H T ^c   Ruffolo, Salvatore C ^d   Thornberry, Nancy A ^c   Xanthoudakis, Steve ^a   Zamboni, Robert J ^a   Roy, Sophie ^a   Nicholson, Donald W ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^c MERCK RESEARCH LABORATORIES   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CAMPTOTHECIN; CASPASE; PEPTIDE;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; BRAIN INJURY; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LOCALIZATION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; NERVE CELL; PATHOGENESIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; TISSUE DISTRIBUTION;

EID: 0033617402     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80748-5     Document Type: Article

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