Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats

Life Sciences

Volumn 71, Issue 6, 2002, Pages 655-665

  Sinha, Kusum ^a   Chaudhary, Geeta ^a   Kumar Gupta, Yogendra ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Antioxidants; Focal cerebral ischemia; Free radicals; MCA; Oxidative stress; Trans resveratrol

Indexed keywords

RESVERATROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; STROKE;

ANIMALS; BRAIN; CEREBROVASCULAR ACCIDENT; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; FREE RADICALS; HAND STRENGTH; ISCHEMIC ATTACK, TRANSIENT; MALE; MALONDIALDEHYDE; MIDDLE CEREBRAL ARTERY; MOTOR ACTIVITY; MUSCLE, SKELETAL; OXIDATIVE STRESS; PLATELET AGGREGATION INHIBITORS; RATS; RATS, WISTAR; REFERENCE VALUES; REPERFUSION INJURY; STILBENES; TIME FACTORS;

ANIMALIA; RATTUS NORVEGICUS; VITACEAE;

EID: 0037189154     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)01691-0     Document Type: Article

References (30)

1. Limiting neurological damage after stroke
2. Pathophysiology and treatment of focal cerebral ischemia; Pt 11; Mechanisms of damage and treatment
3. The effect of 2-chloro adenosine on lipid peroxide level during experimental cerebral ischemia-reperfusion in gerbils
4. The molecular basis of brain injury and brain edema; The role of oxygen free radicals
5. Ebselen: Prospective therapy for cerebral ischemia
6. Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke
7. Neuroprotection by 2-h postischemia administration of two free radical scavengers, alpha-phenyl-n-tert-butyl-nitrone (PBN) and N-tert-butyl-(2-sulfophenyl)-nitrone (S-PBN), in rats subjected to focal embolic cerebral ischemia
8. Neuroprotective effects of the novel brain-penetrating antioxidant U-101033E and the spin-trapping agent alpha-phenyl-N-tert-butyl nitrone (PBN)
9. Alcohol, ischemic heart disease and the French paradox
10. Biological effects of resveratrol
11. Amelioration of oxidative stress by antioxidant and resveratrol in PC12 cells
12. Ethanol induced cell death by lipid peroxidation in PC12 cells
13. The red wine antioxidant resveratrol protects the isolated rat heart from ischemia reperfusion injury
14. 3
15. Partial neuroprotection of invivo exictotoxic brain damage by chronic administration of the red wine antioxidant agents, trans-Resveratrol in rats
16. Experimental studies of ischemic brain edema: A new experimental model of cerebral embolism in rats in which re circulation can be introduced in the ischemic area
17. Neurological deficit and extent of neuronal necrosis attributable to middle artery occlusion in rats
18. Age related learning deficits in transgenic mice expressing the 721-amino acid isoform of human beta-amyloid precursor protein
19. Correlation between motor impairment and infarct volume after permanent and transient middle artery occlusion in the rat
20. Intracerebroventricular administration of streptozotocin causes long term diminution in learning and memory abilities and intracerebral energy metabolism in adults rats
21. Assay of lipid peroxides in animals tissue by thiobarbituraic acid reaction
22. Tissue sulphyldryl groups
23. Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats
24. Evaluation of kinetics parameters of naturally phytoalexin in Resveratrol orally administered in wine to rats
25. Middle cerebral artery occlusion in the rats by intraluminal suture; Neurological and pathological evaluation of an improved model
26. A novel endothelin antagonist, A-127722, attenuates ischemic lesion size in rats with temporary middle cerebral artery occlusion
27. Quinone induced oxidative stress elevates glutathione and induces glutamylcysteine synthetase activity in rat lung epithelial L2 cells
28. Effect of melatonin in on ischemia reperfusion injury induced by middle cerebral artery occlusion in rats
29. Inhibition of nitric oxide synthase as a potential therapeutic target
30. Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide related toxicity in cultured hippocampal neurons