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Volumn 276, Issue 42, 2001, Pages 38837-38843
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Identification of a Class of Small Molecule Inhibitors of the Sirtuin Family of NAD-dependent Deacetylases by Phenotypic Screening
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Author keywords
[No Author keywords available]
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Indexed keywords
DNA;
ENZYMES;
GENES;
GENETIC ENGINEERING;
YEAST;
MOLECULAR INHIBITORS;
BIOCHEMISTRY;
ACYLTRANSFERASE;
ALDEHYDE DERIVATIVE;
ENZYME INHIBITOR;
GENE PRODUCT;
HYDROXYL GROUP;
NICOTINAMIDE ADENINE DINUCLEOTIDE DEPENDENT DEACETYLASE;
REPRESSOR PROTEIN;
RIBOSOME DNA;
SILENT INFORMATION REGULATOR PROTEIN 2;
SIRTUIN;
UNCLASSIFIED DRUG;
BENZAMIDE DERIVATIVE;
FUNGAL PROTEIN;
HISTONE;
HISTONE DEACETYLASE;
NAPHTHOL DERIVATIVE;
SILENT INFORMATION REGULATOR PROTEIN;
SIR2 PROTEIN, S CEREVISIAE;
SIRT1 PROTEIN, HUMAN;
SIRTINOL;
TRANSACTIVATOR PROTEIN;
AGING;
ARABIDOPSIS;
ARTICLE;
CONTROLLED STUDY;
ENZYME INHIBITION;
GENE EXPRESSION;
GENE LOCUS;
GENE SILENCING;
NONHUMAN;
PHENOTYPE;
PRIORITY JOURNAL;
PROTEIN FAMILY;
SCREENING;
TELOMERE;
TRANSCRIPTION REGULATION;
ANIMAL;
DOSE RESPONSE;
DRUG ANTAGONISM;
GENE LIBRARY;
GENETIC PROCEDURES;
GENETIC TRANSCRIPTION;
GENOTYPE;
HELA CELL;
HUMAN;
METABOLISM;
MULTIGENE FAMILY;
MUTAGENESIS;
SERODIAGNOSIS;
STRUCTURE ACTIVITY RELATION;
WESTERN BLOTTING;
ARABIDOPSIS;
EUKARYOTA;
PROKARYOTA;
ANIMALS;
ARABIDOPSIS;
BENZAMIDES;
BLOTTING, WESTERN;
DOSE-RESPONSE RELATIONSHIP, DRUG;
ENZYME INHIBITORS;
FUNGAL PROTEINS;
GENE LIBRARY;
GENETIC TECHNIQUES;
GENOTYPE;
HELA CELLS;
HISTONE DEACETYLASES;
HISTONES;
HUMANS;
MULTIGENE FAMILY;
MUTAGENESIS;
NAPHTHOLS;
PHENOTYPE;
PRECIPITIN TESTS;
SILENT INFORMATION REGULATOR PROTEINS, SACCHAROMYCES CEREVISIAE;
SIRTUINS;
STRUCTURE-ACTIVITY RELATIONSHIP;
TRANS-ACTIVATORS;
TRANSCRIPTION, GENETIC;
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EID: 0035914304
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M106779200 Document Type: Article |
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Times cited : (501)
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References (29)
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