-
1
-
-
0035857449
-
Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization
-
Arendt T. Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization. Neuroscience. 102:2001;723-765
-
(2001)
Neuroscience
, vol.102
, pp. 723-765
-
-
Arendt, T.1
-
3
-
-
0036592518
-
Non-familial Alzheimer's disease is mainly due to genetic factors
-
Ashford J.W., Mortimer J.A. Non-familial Alzheimer's disease is mainly due to genetic factors. J. Alzheimer's Dis. 4:2002;169-177
-
(2002)
J. Alzheimer's Dis.
, vol.4
, pp. 169-177
-
-
Ashford, J.W.1
Mortimer, J.A.2
-
4
-
-
0031278270
-
Lack of apolipoprotein e dramatically reduces amyloid beta-peptide deposition
-
Bales K.R., Verina T., Dodel R.C., Du Y., Altstiel L., Bender M., et al. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition. Nat. Genet. 17:1997;263-264
-
(1997)
Nat. Genet.
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Dodel, R.C.3
Du, Y.4
Altstiel, L.5
Bender, M.6
-
6
-
-
0037115049
-
Modulation of Alzheimer-like synaptic and choninergic deficits in transgenic mice by human apolipoprotein e depends on isoform, aging, and overexpression of amyloid β peptides but not on plaque formation
-
Buttini M., Shockley K., Huang Y., Jones B., Masliah E., Mallory M., et al. Modulation of Alzheimer-like synaptic and choninergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid β peptides but not on plaque formation. J. Neurosci. 22:2002;10539-10548
-
(2002)
J. Neurosci.
, vol.22
, pp. 10539-10548
-
-
Buttini, M.1
Shockley, K.2
Huang, Y.3
Jones, B.4
Masliah, E.5
Mallory, M.6
-
7
-
-
0035061891
-
Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Ab aggregation
-
Cho H.S., Hyman B.T., Greenberg S.M., Rebeck G.W. Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Ab aggregation. J. Neuropathol. Exp. Neurol. 60:2001;342-349
-
(2001)
J. Neuropathol. Exp. Neurol.
, vol.60
, pp. 342-349
-
-
Cho, H.S.1
Hyman, B.T.2
Greenberg, S.M.3
Rebeck, G.W.4
-
8
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:1993;921-923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
-
9
-
-
0028831614
-
The apolipoprotein e E4 allele and sex-specific risk of Alzheimer's disease [letter comment]
-
Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.J., Roses A.D., et al. The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease [letter comment]. JAMA. 273:1995;373-374
-
(1995)
JAMA
, vol.273
, pp. 373-374
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.J.5
Roses, A.D.6
-
10
-
-
0028203997
-
Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease-prevalence
-
Czech C., Horstl H., Hentschel F., Monning U., Besthorn C., Geigerkabish C., et al. Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease-prevalence. Eur. Arch. Psychiat. Clin. Neurosci. 243:1994;291-292
-
(1994)
Eur. Arch. Psychiat. Clin. Neurosci.
, vol.243
, pp. 291-292
-
-
Czech, C.1
Horstl, H.2
Hentschel, F.3
Monning, U.4
Besthorn, C.5
Geigerkabish, C.6
-
11
-
-
0030614816
-
Apolipoprotein e epsilon4 and incidence of Alzheimer disease in a community population of older persons
-
Evans D.A., Beckett L.A., Field T.S., Feng L., Albert M.S., Bennett D.A., et al. Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons. JAMA. 12(277):1997;822-824
-
(1997)
JAMA
, vol.12
, Issue.277
, pp. 822-824
-
-
Evans, D.A.1
Beckett, L.A.2
Field, T.S.3
Feng, L.4
Albert, M.S.5
Bennett, D.A.6
-
12
-
-
0036233168
-
Human and murine apoE markedly alters a beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease
-
Fagan A.M., Watson M., Parsadanian M., Bales K.R., Paul S.M., Holtzman D.M. Human and murine apoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiol. Dis. 9:2002;305-318
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 305-318
-
-
Fagan, A.M.1
Watson, M.2
Parsadanian, M.3
Bales, K.R.4
Paul, S.M.5
Holtzman, D.M.6
-
13
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein e genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
-
Farrer L.A., Cupples L.A., Haines J.L., Hyman B., Kukull W.A., Mayeux R., et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA. 278:1997;1349-1356
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
-
15
-
-
0033799573
-
Apolipoprotein e variation at the sequence haplotype level: Implications for the origin and maintenance of a major human polymorphism
-
Fullerton S.M., Clark A.G., Weiss K.M., Nickerson D.A., Taylor S.L., Stengard J.H., et al. Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism. Am J. Hum. Genet. 67:2000;881-900
-
(2000)
Am J. Hum. Genet.
, vol.67
, pp. 881-900
-
-
Fullerton, S.M.1
Clark, A.G.2
Weiss, K.M.3
Nickerson, D.A.4
Taylor, S.L.5
Stengard, J.H.6
-
16
-
-
0035930837
-
The reliability theory of aging and longevity
-
Gavrilov L.A., Gavrilova N.S. The reliability theory of aging and longevity. J. Theor. Biol. 213:2001;527-545
-
(2001)
J. Theor. Biol.
, vol.213
, pp. 527-545
-
-
Gavrilov, L.A.1
Gavrilova, N.S.2
-
17
-
-
0031664361
-
High frequency of apolipoprotein e epsilon4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes
-
Ghebremedhin E., Schultz C., Braak E., Braak H. High frequency of apolipoprotein E epsilon4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes. Exp. Neurol. 153:1998;152-155
-
(1998)
Exp. Neurol.
, vol.153
, pp. 152-155
-
-
Ghebremedhin, E.1
Schultz, C.2
Braak, E.3
Braak, H.4
-
18
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 297:2002;353-356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
19
-
-
0141814636
-
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer disease-like neurodegeneration and behavioral deficits in transgenic mice
-
Harris F.M., Brecht W.J., Xu Q., Tesseur I., Kekonius L., Wyss-Coray T., et al. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer disease-like neurodegeneration and behavioral deficits in transgenic mice. Proc Natl Acad Sci USA. 100:2003;10966-10971
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10966-10971
-
-
Harris, F.M.1
Brecht, W.J.2
Xu, Q.3
Tesseur, I.4
Kekonius, L.5
Wyss-Coray, T.6
-
20
-
-
0035857377
-
Incidence of dementia and Alzheimer's disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana
-
Hendrie H.C., Ogunniyi A., Hall K.S., Bayewu O., Unverzagt F.W., Gurejo O., et al. Incidence of dementia and Alzheimer's disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana. JAMA. 285:2001;739-747
-
(2001)
JAMA
, vol.285
, pp. 739-747
-
-
Hendrie, H.C.1
Ogunniyi, A.2
Hall, K.S.3
Bayewu, O.4
Unverzagt, F.W.5
Gurejo, O.6
-
21
-
-
0028274607
-
Can an improved environment cause maximum lifespan to decrease? Comments on lifespan criteria and longitudinal Gompertzian analysis
-
Hirsch H.R. Can an improved environment cause maximum lifespan to decrease? Comments on lifespan criteria and longitudinal Gompertzian analysis. Exp. Gerontol. 29:1994;119-137
-
(1994)
Exp. Gerontol.
, vol.29
, pp. 119-137
-
-
Hirsch, H.R.1
-
22
-
-
0028935409
-
Do intersections of mortality-rate and survival functions have significance?
-
Hirsch H.R. Do intersections of mortality-rate and survival functions have significance? Exp. Gerontol. 30:1995;147-167
-
(1995)
Exp. Gerontol.
, vol.30
, pp. 147-167
-
-
Hirsch, H.R.1
-
23
-
-
0031006081
-
Intersections of mortality-rate and survival functions: Model-independent considerations
-
Hirsch H.R. Intersections of mortality-rate and survival functions: model-independent considerations. Exp Gerontol. 32:1997;287-296
-
(1997)
Exp Gerontol.
, vol.32
, pp. 287-296
-
-
Hirsch, H.R.1
-
24
-
-
4243215848
-
Apolipoprotein e isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
-
Holtzman D.M., Bales K.R., Tenkova T., Fagan A.M., Parsadanian M., Sartorius L.J., et al. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 97:2000;2892-2897
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2892-2897
-
-
Holtzman, D.M.1
Bales, K.R.2
Tenkova, T.3
Fagan, A.M.4
Parsadanian, M.5
Sartorius, L.J.6
-
25
-
-
0035902514
-
Apolipoprotein e fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons
-
Huang Y., Liu X.Q., Wyss-Coray T., Brecht W.J., Sanan D.A., Mahley R.W. Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. Proc. Natl. Acad. Sci. USA. 98:2001;8838-8843
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 8838-8843
-
-
Huang, Y.1
Liu, X.Q.2
Wyss-Coray, T.3
Brecht, W.J.4
Sanan, D.A.5
Mahley, R.W.6
-
26
-
-
4143091289
-
Apolipoprotein E: Diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease
-
Huang Y, Weisgraber KH, Mucke L, Mahley RW. Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease. J Mol Neurosci 2004;32:187-202.
-
(2004)
J Mol Neurosci
, vol.32
, pp. 187-202
-
-
Huang, Y.1
Weisgraber, K.H.2
Mucke, L.3
Mahley, R.W.4
-
28
-
-
0031720801
-
The incidence of dementia: A meta-analysis
-
Jorm A.F., Jolley D. The incidence of dementia: a meta-analysis. Neurology. 51:1998;728-733
-
(1998)
Neurology
, vol.51
, pp. 728-733
-
-
Jorm, A.F.1
Jolley, D.2
-
29
-
-
0027931854
-
Isoform-specific binding of apolipoprotein e to b-amyloid
-
LaDu M.J., Falduto M.T., Manelli A.M., Reardon C.A., Getz G.S., Frail D.E. Isoform-specific binding of apolipoprotein E to b-amyloid. J. Biol. Chem. 269:1994;23403-23406
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23403-23406
-
-
Ladu, M.J.1
Falduto, M.T.2
Manelli, A.M.3
Reardon, C.A.4
Getz, G.S.5
Frail, D.E.6
-
30
-
-
0028906808
-
Purification of apolipoprotein e attenuates isoform-specific binding to β-amyloid
-
LaDu M.J., Pederson T.M., Frail D.E., Reardon C.A., Getz G.S., Falduto M.T. Purification of apolipoprotein E attenuates isoform-specific binding to β-amyloid. J. Biol. Chem. 270:1995;9039-9042
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9039-9042
-
-
Ladu, M.J.1
Pederson, T.M.2
Frail, D.E.3
Reardon, C.A.4
Getz, G.S.5
Falduto, M.T.6
-
31
-
-
0043095312
-
Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype
-
Lanz T.A., Carter D.B., Merchant K.M. Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype. Neurobiol Dis. Aug. 13:2003;246-253
-
(2003)
Neurobiol Dis. Aug
, vol.13
, pp. 246-253
-
-
Lanz, T.A.1
Carter, D.B.2
Merchant, K.M.3
-
32
-
-
0042093508
-
ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory
-
Levi O., Jongen-Relo A.L., Feldon J., Roses A.D., Michaelson D.M. ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory. Neurobiol. Dis. 13:2003;273-282
-
(2003)
Neurobiol. Dis.
, vol.13
, pp. 273-282
-
-
Levi, O.1
Jongen-Relo, A.L.2
Feldon, J.3
Roses, A.D.4
Michaelson, D.M.5
-
33
-
-
0028173205
-
1-antichymotrypsin and apolipoprotein e promote assembly of Alzheimer b-protein into filaments
-
1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer b-protein into filaments. Nature. 372:1994;92-94
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer Jr., H.B.3
Das, S.4
Potter, H.5
-
34
-
-
2542430827
-
Apolipoprotein E. Structure and function in lipid metabolism and neurobiology
-
Rosenberg RN, Prusiner SB, DiMauro S, Barchi RL, Nestler EJ, editors. Philadelphia: Butterworth Heinemann;
-
Mahley R, Huang Y, Apolipoprotein E. Structure and function in lipid metabolism and neurobiology. In: Rosenberg RN, Prusiner SB, DiMauro S, Barchi RL, Nestler EJ, editors. The molecular and genetic basis of neurologic and psychiatric disease, third ed. Philadelphia: Butterworth Heinemann; 2003. p. 565-73.
-
(2003)
The Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Third Ed.
, pp. 565-573
-
-
Mahley, R.1
Huang, Y.2
-
35
-
-
0032545939
-
Utility of the apolipoprotein e genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein e and Alzheimer's Disease
-
Mayeux R., Saunders A.M., Shea S., Mirra S., Evans D., Roses A.D., et al. Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease. N. Engl. J. Med. 338:1998;506-511
-
(1998)
N. Engl. J. Med.
, vol.338
, pp. 506-511
-
-
Mayeux, R.1
Saunders, A.M.2
Shea, S.3
Mirra, S.4
Evans, D.5
Roses, A.D.6
-
36
-
-
0029877490
-
Apolipoprotein e polymorphism is associated with both senile plaque load and Alzheimer-type neurofibrillary tangle formation
-
Marz W., Scharnagl H., Kirca M., Bohl J., Gross W., Ohm T.G. Apolipoprotein E polymorphism is associated with both senile plaque load and Alzheimer-type neurofibrillary tangle formation. Ann N Y Acad. Sci. 777:1996;276-280
-
(1996)
Ann N Y Acad. Sci.
, vol.777
, pp. 276-280
-
-
Marz, W.1
Scharnagl, H.2
Kirca, M.3
Bohl, J.4
Gross, W.5
Ohm, T.G.6
-
37
-
-
0034509333
-
A plasticity-based theory of the pathogenenesis of Alzeimer's disease
-
Mesulam M.M. A plasticity-based theory of the pathogenenesis of Alzeimer's disease. Ann. N. Y. Acad. Sci. 924:2000;42-52
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.924
, pp. 42-52
-
-
Mesulam, M.M.1
-
38
-
-
0037154236
-
Incidence of AD may decline in the early 90s for men, later for women: The Cache County study
-
Miech R.A., Breitner J.C., Zandi P.P., Khachaturian A.S., Anthony J.C., Mayer L. Incidence of AD may decline in the early 90s for men, later for women: the Cache County study. Neurology. 58:2002;209-218
-
(2002)
Neurology
, vol.58
, pp. 209-218
-
-
Miech, R.A.1
Breitner, J.C.2
Zandi, P.P.3
Khachaturian, A.S.4
Anthony, J.C.5
Mayer, L.6
-
39
-
-
0033528666
-
Differential effects of apolipoprotein e isoforms on metal-induced aggregation of Ab using physiological concentrations
-
Moir R.D., Atwood C.S., Romano D.M., Laurans M.H., Huang X., Bush A.I., et al. Differential effects of apolipoprotein E isoforms on metal-induced aggregation of Ab using physiological concentrations. Biochemistry. 38:1999;4595-4603
-
(1999)
Biochemistry
, vol.38
, pp. 4595-4603
-
-
Moir, R.D.1
Atwood, C.S.2
Romano, D.M.3
Laurans, M.H.4
Huang, X.5
Bush, A.I.6
-
40
-
-
0028787064
-
Influence of the apolipoprotein e genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease
-
Nagy Z.S., Esiri M.M., Jobst K.A., Johnston C., Lichtfiel S., Sim E., et al. Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease. Neuroscience. 69:1995;757-761
-
(1995)
Neuroscience
, vol.69
, pp. 757-761
-
-
Nagy, Z.S.1
Esiri, M.M.2
Jobst, K.A.3
Johnston, C.4
Lichtfiel, S.5
Sim, E.6
-
41
-
-
0025971426
-
Apolipoprotein e immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease
-
Namba Y., Tomonoga M., Kawasaki E., Ikeda K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res. 541:1991;163-166
-
(1991)
Brain Res.
, vol.541
, pp. 163-166
-
-
Namba, Y.1
Tomonoga, M.2
Kawasaki, E.3
Ikeda, K.4
-
42
-
-
0032168460
-
Isoform-specific effects of human apolipoprotein e on brain function revealed in ApoE knockout mice: Increased susceptibility of females
-
Raber J., Wong D., Buttini M., Orth M., Bellosta S., Pitas R.E., et al. Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females. Proc. Natl. Acad. Sci. USA. 95:1998;10914-10919
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10914-10919
-
-
Raber, J.1
Wong, D.2
Buttini, M.3
Orth, M.4
Bellosta, S.5
Pitas, R.E.6
-
43
-
-
0034704816
-
Apolipoprotein e and cognitive performance
-
Raber J., Wong D., Yu G.Q., Buttini M., Mahley R.W., Pitas R.E., et al. Apolipoprotein E and cognitive performance. Nature. 404:2000;352-354
-
(2000)
Nature
, vol.404
, pp. 352-354
-
-
Raber, J.1
Wong, D.2
Yu, G.Q.3
Buttini, M.4
Mahley, R.W.5
Pitas, R.E.6
-
44
-
-
0037096337
-
Androgens protect against apolipoprotein E4-indiced cognitive deficits
-
Raber J., Bonger G., LeFevour A., Buttini M., Mucke L. Androgens protect against apolipoprotein E4-indiced cognitive deficits. J. Neurosci. 22:2002;5204-5209
-
(2002)
J. Neurosci.
, vol.22
, pp. 5204-5209
-
-
Raber, J.1
Bonger, G.2
Lefevour, A.3
Buttini, M.4
Mucke, L.5
-
45
-
-
0027973579
-
Lower cognitive performance in normal older adult male twins carrying the apolipoprotein e epsilon 4 allele
-
Reed T., Carmelli D., Swan G.E., Breitner J.C., Welsh K.A., Jarvik G.P., et al. Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E epsilon 4 allele. Arch. Neurol. 51:1994;1189-1192
-
(1994)
Arch. Neurol.
, vol.51
, pp. 1189-1192
-
-
Reed, T.1
Carmelli, D.2
Swan, G.E.3
Breitner, J.C.4
Welsh, K.A.5
Jarvik, G.P.6
-
46
-
-
0028997817
-
Apolipoprotein e genotyping in the differential diagnosis, not prediction, of Alzheimer's disease
-
Roses A.D. Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease. Ann Neurol. 38:1995;6-14
-
(1995)
Ann Neurol.
, vol.38
, pp. 6-14
-
-
Roses, A.D.1
-
47
-
-
0030481305
-
Apolipoprotein e and Alzheimer's disease. A rapidly expanding field with medical and epidemiological consequences
-
Roses A.D. Apolipoprotein E and Alzheimer's disease. A rapidly expanding field with medical and epidemiological consequences. Ann. N Y Acad. Sci. 802:1996;50-57
-
(1996)
Ann. N Y Acad. Sci.
, vol.802
, pp. 50-57
-
-
Roses, A.D.1
-
48
-
-
0028026587
-
Apolipoprotein e associates with b amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3
-
Sanan D.A., Weisgraber K.H., Russell S.J., Mahley R.W., Huang D., Saunders A., et al. Apolipoprotein E associates with b amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. J. Clin. Invest. 94:1994;860-869
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 860-869
-
-
Sanan, D.A.1
Weisgraber, K.H.2
Russell, S.J.3
Mahley, R.W.4
Huang, D.5
Saunders, A.6
-
49
-
-
0027327267
-
Association of apolipoprotein e allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders A.M., Strittmatter W.J., Schmechel D., George-Hyslop P.H., Pericak-Vance M.A., Joo S.H., et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology. 43:1993;1467-1472
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
-
50
-
-
0027365822
-
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein-E genotype in late-onset Alzheimer disease
-
Schmechel D.E., Saunders A.M., Strittmatter W.J., Crain B.J., Hulette C.M., Joo S.H., et al. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein-E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA. 90:1993;9649-9653
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
Crain, B.J.4
Hulette, C.M.5
Joo, S.H.6
-
51
-
-
0035950225
-
Clearing the brain's amyloid cobwebs
-
Selkoe D.J. Clearing the brain's amyloid cobwebs. Neuron. 32:2001;177-180
-
(2001)
Neuron
, vol.32
, pp. 177-180
-
-
Selkoe, D.J.1
-
52
-
-
0037317248
-
Familial patterns of risk in very late-onset Alzheimer disease
-
Silverman J.M., Smith C.J., Marin D.B., Mohs R.C., Propper C.B. Familial patterns of risk in very late-onset Alzheimer disease. Arch. Gen. Psychiatry. 60:2003;190-197
-
(2003)
Arch. Gen. Psychiatry
, vol.60
, pp. 190-197
-
-
Silverman, J.M.1
Smith, C.J.2
Marin, D.B.3
Mohs, R.C.4
Propper, C.B.5
-
53
-
-
12944259210
-
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
-
Small G.W., Ercoli L.M., Silverman D.H., Huang S.C., Komo S., Bookheimer S.Y., et al. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 97:2000;6037-6042
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6037-6042
-
-
Small, G.W.1
Ercoli, L.M.2
Silverman, D.H.3
Huang, S.C.4
Komo, S.5
Bookheimer, S.Y.6
-
54
-
-
12044254746
-
Binding of human apolipoprotein e to synthetic amyloid (peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
-
Strittmatter W.J., Weisgraber K.H., Huang D.Y., Dong L-M., Salvesen G.S., Pericak-Vance M. Binding of human apolipoprotein E to synthetic amyloid (peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA. 90:1993;8098-8102
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8098-8102
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Huang, D.Y.3
Dong, L.-M.4
Salvesen, G.S.5
Pericak-Vance, M.6
-
55
-
-
0033889344
-
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice
-
Tesseur I., Van Dorpe J., Spittaels K., Van den Haute C., Moechars D., Van Leuven F. Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice. Am J. Pathol. 156:2000;951-964
-
(2000)
Am J. Pathol.
, vol.156
, pp. 951-964
-
-
Tesseur, I.1
Van Dorpe, J.2
Spittaels, K.3
Van Den Haute, C.4
Moechars, D.5
Van Leuven, F.6
-
56
-
-
0037010297
-
Neuroplasticity in Alzheimer's disease
-
Teter B., Ashford J.W. Neuroplasticity in Alzheimer's disease. J. Neurosci. Res. 70:2002;402-437
-
(2002)
J. Neurosci. Res.
, vol.70
, pp. 402-437
-
-
Teter, B.1
Ashford, J.W.2
-
57
-
-
0030804828
-
Neurotoxicity of the 22 kDa thrombin-cleavage fragment of apolipoprotein e and related synthetic peptides is receptor-mediated
-
Tolar M., Marques M.A., Harmony J.A.K., Crutcher K.A. Neurotoxicity of the 22 kDa thrombin-cleavage fragment of apolipoprotein E and related synthetic peptides is receptor-mediated. J. Neurosci. 17:1997;5678-5686
-
(1997)
J. Neurosci.
, vol.17
, pp. 5678-5686
-
-
Tolar, M.1
Marques, M.A.2
Harmony, J.A.K.3
Crutcher, K.A.4
-
58
-
-
0033567074
-
Truncated apolipoprotein e (apoE) causes increased intracellular calcium and may mediate apoE neurotoxicity
-
Tolar M., Keller J.N., Chan S., Mattson M.P., Marques M.A., Crutcher K.A. Truncated apolipoprotein E (apoE) causes increased intracellular calcium and may mediate apoE neurotoxicity. J. Neurosci. 19:1999;7100-7110
-
(1999)
J. Neurosci.
, vol.19
, pp. 7100-7110
-
-
Tolar, M.1
Keller, J.N.2
Chan, S.3
Mattson, M.P.4
Marques, M.A.5
Crutcher, K.A.6
-
59
-
-
0037469193
-
APOE E4 is a determininant for Alzheimer type pathology in progressive supranuclear palsy
-
Tsuboi Y., Josephs K.A., Cookson N., Dickson D.W. APOE E4 is a determininant for Alzheimer type pathology in progressive supranuclear palsy. Neurology. 60:2003;240-245
-
(2003)
Neurology
, vol.60
, pp. 240-245
-
-
Tsuboi, Y.1
Josephs, K.A.2
Cookson, N.3
Dickson, D.W.4
-
60
-
-
2542477634
-
Longitudinal functional alterations in asymptotic women at risk for Alzheimer's disease
-
Umberger GHH, Andersen AH, Kryscio RJ, Blonder LX, Schmitt FA, Wekstein DA, et al. Longitudinal functional alterations in asymptotic women at risk for Alzheimer's disease. Society for Neuroscience Abstract; 2003. p. 240.7.
-
(2003)
Society for Neuroscience Abstract
, pp. 2407
-
-
Umberger, G.H.H.1
Andersen, A.H.2
Kryscio, R.J.3
Blonder, L.X.4
Schmitt, F.A.5
Wekstein, D.A.6
-
61
-
-
0032457459
-
Apolipoprotein E4 promotes incipient Alzheimer pathology in the elderly
-
Warzok R.W., Kessler C., Apel G., Schwarz A., Egensperger R., Schreiber D., et al. Apolipoprotein E4 promotes incipient Alzheimer pathology in the elderly. Alzheimer Dis. Assoc. Disord. 12:1998;33-39
-
(1998)
Alzheimer Dis. Assoc. Disord.
, vol.12
, pp. 33-39
-
-
Warzok, R.W.1
Kessler, C.2
Apel, G.3
Schwarz, A.4
Egensperger, R.5
Schreiber, D.6
-
62
-
-
0027970307
-
Acceleration of Alzheimer's fibril formation by apolipoprotein e in vitro
-
Wisniewski T., Castaño E.M., Golabek A., Vogel T., Frangione B. Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am. J. Pathol. 145:1994;1030-1035
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1030-1035
-
-
Wisniewski, T.1
Castaño, E.M.2
Golabek, A.3
Vogel, T.4
Frangione, B.5
-
63
-
-
0028924083
-
Is Alzheimer's disease an apolipoprotein e amyloidosis?
-
Wisniewski T., Lalowski M., Golabek A., Vogel T., Frangione B. Is Alzheimer's disease an apolipoprotein E amyloidosis? Lancet. 345:1995;956-958
-
(1995)
Lancet
, vol.345
, pp. 956-958
-
-
Wisniewski, T.1
Lalowski, M.2
Golabek, A.3
Vogel, T.4
Frangione, B.5
-
64
-
-
0030870127
-
Apolipoprotein e phenotype and cognitive decline in a prospective study of elderly community women
-
Yaffe K., Cauley J., Sands L., Browner W. Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women. Arch. Neurol. 54:1997;1110-1114
-
(1997)
Arch. Neurol
, vol.54
, pp. 1110-1114
-
-
Yaffe, K.1
Cauley, J.2
Sands, L.3
Browner, W.4
|