β-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways

Journal of Neurochemistry

Volumn 92, Issue 3, 2005, Pages 628-636

  Tamagno, Elena ^a   Parola, Maurizio ^a   Bardini, Paola ^a   Piccini, Alessandra ^b   Borghi, Roberta ^b   Guglielmotto, Michela ^a   Santoro, Gianni ^a   Davit, Annalisa ^a   Danni, Oliviero ^a   Smith, M A ^c   Perry, G ^c   Tabaton, Massimo ^b  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

site APP cleaving enzyme; 4 hydroxynonenal; Alzheimer's disease; Cell signaling; Oxidative stress; Stress activated protein kinase

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 HYDROXYNONENAL; AMYLOID BETA PROTEIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BETA SECRETASE; CASPASE 3; CYCLOHEXIMIDE; DACTINOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PROTEIN SERINE THREONINE KINASE; STAT PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME MECHANISM; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NERVE CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALDEHYDES; AMYLOID PRECURSOR PROTEIN SECRETASES; APOPTOSIS; ASPARTIC ENDOPEPTIDASES; CELL LINE; DNA-BINDING PROTEINS; ENDOPEPTIDASES; ENZYME ACTIVATORS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; UP-REGULATION;

EID: 19944433845     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02895.x     Document Type: Article

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