Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats

Life Sciences

Volumn 71, Issue 21, 2002, Pages 2489-2498

  Sharma, Monisha ^a   Gupta, Y K ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Free radicals; ICV; Rat; Streptozotocin; Trans resveratrol

Indexed keywords

GLUTATHIONE; MALONALDEHYDE; RESVERATROL; STREPTOZOCIN;

ANIMAL BEHAVIOR; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BRAIN LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; LEARNING; LIPID PEROXIDATION; MALE; MAZE TEST; MEMORY; MORTALITY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PASSIVE AVOIDANCE; RAT; TASK PERFORMANCE;

ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; INJECTIONS, INTRAVENTRICULAR; LEARNING; MALE; OXIDATIVE STRESS; RATS; RATS, WISTAR; STILBENES; STREPTOZOCIN;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0037063709     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)02083-0     Document Type: Article

References (26)

1. Cantuti-Castelvetri I., Shukitt-Hale B., Joseph J.A. Neurobehavioral aspects of antioxidants in aging. International Journal of Developmental Neuroscience. 18(4-5):2000;367-381.
2. Launer L.J., Kalmijn S. Anti-oxidants and cognitive function: a review of clinical and epidemiological studies. Journal of Neural Transmission. 53:1998;1-8.
3. Zs-Nagy I.A., Dercekei B., Lustyik G. Age dependent changes in the osmometric behavior of rat brain and liver. Archives of Gerontology and Geriatrics. 6:1987;339-354.
4. Fremont L. Biological effects of resveratrol. Life Sciences. 66(8):2000;663-673.
5. Constant J. Alcohol, ischemic heart disease and the French paradox. Coronary Artery Disease. 8:1997;645-649.
6. Das D.K., Sato M., Ray P.S., Maulik G., Engelman R.M., Bertelli A.A., Bertelli A. Cardioprotection of red wine: role of polyphenolic antioxidants. Drugs Experimental Clinical Research. 25(2-3):1999;115-120.
7. 3. Free Radical Biology and Medicine. 26(11/12):1999;1531-1537.
8. Sun A.Y., Chen Y.M., Kracke M.J., Wixom P., Chen Y. Ethanol induced cell death by lipid peroxidation in PC12 cells. Neurochemical Research. 22:1997;1187-1192.
9. Ray P.S., Maulik G., Cordis G.A., Bertelli A.A., Bertelli A., Das D.K. The red wine antioxidant resveratrol protects the isolated rat heart from ischemia reperfusion injury. Free Radical Biology and Medicine. 27:1999;160-169.
10. Lannert H., Hoyer S. Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats. Behavioral Neuroscience. 112(5):1998;1199-1208.
11. Blokland A., Jolles J. Spatial learning deficit and reduced hippocampal ChAT activity in rats after an ICV injection of streptozotocin. Pharmacology Biochemistry and Behavior. 44(2):1993;491-494.
12. Sharma M., Gupta Y.K. Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment. Life Sciences. 68/9:2000;1021-1029.
13. Virgili M., Contestabile A. Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans resveratrol in rats. Neuroscience Letters. 281(2-3):2000;123-126.
14. Nakahara N., Iga Y., Mizobe F., Kawanishi G. Effects of intracerebroventricular injection of AF64A on learning behaviors in rats. Japanese Journal of Pharmacology. 48(1):1998;121-130.
15. Sharma A.C., Kulkarni S.K. Evaluation of learning and memory mechanisms employing elevated plus-maze in rats and mice. Progress in Neuropsychopharmacology Biology and Psychiatry. 16(1):1992;117-125.
16. Okhawa H., Ohishi N., Yagi K. Assay of lipid peroxides in animals tissue by thiobarbituraic acid reaction. Analytical Biochemistry. 95:1979;351-358.
17. Ellman G.L. Tissue sulphydryl groups. Archives of Biochemistry and Biophysics. 82:1959;70-77.
18. Sun AY, Simonyi A, Sun GY. The "French paradox" and beyond: neuroprotective effects of polyphenols. Free Radical Biology and Medicine 2002;15;32(4):314-318.
19. Chanvitayapongs S., Draczynska L.B., Sun A.Y. Amelioration of oxidative stress by antioxidant and resveratrol in PC12 cells. Neuroreport. 8:1997;1499-1502.
20. Gupta Y.K., Briyal S., Chaudhary G. Protective effect of trans-resveratrol against kainic acid-induced seizures and oxidative stress in rats. Pharmacology Biochemistry and Behavior. 71(1-2):2002;245-249.
21. Gupta Y.K., Chaudhary G., Sinha K., Srivastava A.K. Protective effect of resveratrol against intracortical FeCl3-induced model of posttraumatic seizures in rats. Methods Findings in Experimental and Clinical Pharmacology. 23(5):2001;241-244.
22. Sinha K., Chaudhary G., Gupta Y.K. Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats. Life Sci. 2002;. [In press].
23. Lannert H., Wirtz P., Schuhmann V., Galmbacher R. Effects of Estradiol [-17[beta]] on learning, memory and cerebral energy metabolism in male rats after intracerebroventricular administration of streptozotocin. Journal of Neural Transmission. 105:1998;1045-1063.
24. Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK, Lee SS. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutatation Research 2001;480-481:243-68.
25. Draczynska-Lusiak B, Chen YM, Sun AY. Oxidized lipoproteins activate NF-kappaB binding activity and apoptosis in PC12 cells. Neuroreport 1998;16;9(3):527-32.
26. Tredici G., Miloso M., Nicolini G., Galbiati S., Cavaletti G., Bertelli A. Resveratrol, map kinases and neuronal cells: might wine be a neuroprotectant? Drugs Experimental Clinical Research. 25(2-3):1999;99-103.