-
1
-
-
13844314148
-
Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs
-
SHITARA Y, SATO H, SUGIYAMA Y: Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs. Ann. Rev. Pharmacol. Toxicol. (2005) 45:689-723.
-
(2005)
Ann. Rev. Pharmacol. Toxicol
, vol.45
, pp. 689-723
-
-
SHITARA, Y.1
SATO, H.2
SUGIYAMA, Y.3
-
2
-
-
0042391834
-
Transporter-mediated drug interactions
-
TSUJI A: Transporter-mediated drug interactions. Drug Metab. Pharmacokinet. (2002) 17(4):253-274.
-
(2002)
Drug Metab. Pharmacokinet
, vol.17
, Issue.4
, pp. 253-274
-
-
TSUJI, A.1
-
3
-
-
33644835354
-
The role of transporters in drug interactions
-
ENDUES CJ, HSIAO P, CHUNG FS, UNADKAT JD: The role of transporters in drug interactions. Eur J. Pharm. Sci. (2006) 27(5):501-517.
-
(2006)
Eur J. Pharm. Sci
, vol.27
, Issue.5
, pp. 501-517
-
-
ENDUES, C.J.1
HSIAO, P.2
CHUNG, F.S.3
UNADKAT, J.D.4
-
4
-
-
0031947633
-
Drug interactions at the renal level. Implications for drug development
-
BONATE PL, REITH K, WEIR S: Drug interactions at the renal level. Implications for drug development. Clin. Pharmacokinet. (1998) 34(5):375-404.
-
(1998)
Clin. Pharmacokinet
, vol.34
, Issue.5
, pp. 375-404
-
-
BONATE, P.L.1
REITH, K.2
WEIR, S.3
-
5
-
-
0027133590
-
Mechanisms mediating renal secretion of organic anions and cations
-
PRITCHARD JB, MILLER DS: Mechanisms mediating renal secretion of organic anions and cations. Physiol. Rev. (1993) 73(4):765-796.
-
(1993)
Physiol. Rev
, vol.73
, Issue.4
, pp. 765-796
-
-
PRITCHARD, J.B.1
MILLER, D.S.2
-
6
-
-
3042542425
-
Molecular and cellular physiology of renal organic cation and anion transport
-
WRIGHT SH, DANTZLER WH: Molecular and cellular physiology of renal organic cation and anion transport. Physiol. Rev. (2004) 84(3):987-1049.
-
(2004)
Physiol. Rev
, vol.84
, Issue.3
, pp. 987-1049
-
-
WRIGHT, S.H.1
DANTZLER, W.H.2
-
7
-
-
0031800792
-
Role of organic cation transporters in drug absorption and elimination
-
ZHANG L, BRETT CM, GIACOMINI KM: Role of organic cation transporters in drug absorption and elimination. Ann. Rev. Pharmacol. Toxicol. (1998) 38:431-460.
-
(1998)
Ann. Rev. Pharmacol. Toxicol
, vol.38
, pp. 431-460
-
-
ZHANG, L.1
BRETT, C.M.2
GIACOMINI, K.M.3
-
8
-
-
0029820968
-
Peptide transporters in the intestine and the kidney
-
LEIBACH FH, GANAPATHY V: Peptide transporters in the intestine and the kidney. Ann. Rev. Nutr. (1996) 16:99-119.
-
(1996)
Ann. Rev. Nutr
, vol.16
, pp. 99-119
-
-
LEIBACH, F.H.1
GANAPATHY, V.2
-
9
-
-
1442302331
-
Mammalian nucleoside transporters
-
KONG W, ENGEL K, WANG J: Mammalian nucleoside transporters. Curr. Drug Metab. (2004) 5(1):63-84.
-
(2004)
Curr. Drug Metab
, vol.5
, Issue.1
, pp. 63-84
-
-
KONG, W.1
ENGEL, K.2
WANG, J.3
-
10
-
-
0033849976
-
Cellular and molecular aspects of drug transport in the kidney
-
INUI KI, MASUDA S, SAITO H: Cellular and molecular aspects of drug transport in the kidney. Kidney Int. (2000) 58(3):944-958.
-
(2000)
Kidney Int
, vol.58
, Issue.3
, pp. 944-958
-
-
INUI, K.I.1
MASUDA, S.2
SAITO, H.3
-
11
-
-
1342344851
-
Transporters and renal drug elimination
-
LEE W, KIM RB: Transporters and renal drug elimination. Ann. Rev. Pharmacol. Toxicol. (2004) 44:137-166.
-
(2004)
Ann. Rev. Pharmacol. Toxicol
, vol.44
, pp. 137-166
-
-
LEE, W.1
KIM, R.B.2
-
12
-
-
0035209269
-
Mechanisms and clinical implications of renal drug excretion
-
MASEREEUW R, RUSSEL FG: Mechanisms and clinical implications of renal drug excretion. Drug Metab. Rev. (2001) 33(3-4):299-351.
-
(2001)
Drug Metab. Rev
, vol.33
, Issue.3-4
, pp. 299-351
-
-
MASEREEUW, R.1
RUSSEL, F.G.2
-
13
-
-
29144523534
-
A human transporter protein that mediates the final excretion step for toxic organic cations
-
OTSUKA M, MATSUMOTO T, MORIMOTO R et al.: A human transporter protein that mediates the final excretion step for toxic organic cations. Proc. Natl. Acad. Sci. USA (2005) 102(50):17923-17928.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.50
, pp. 17923-17928
-
-
OTSUKA, M.1
MATSUMOTO, T.2
MORIMOTO, R.3
-
15
-
-
0036842911
-
Structure, function, and regulation of renal organic anion transporters
-
YOU G: Structure, function, and regulation of renal organic anion transporters. Med. Res. Rev. (2002) 22(6):602-616.
-
(2002)
Med. Res. Rev
, vol.22
, Issue.6
, pp. 602-616
-
-
YOU, G.1
-
17
-
-
0034817065
-
Isolation of a family of organic anion transporters from human liver and kidney
-
SUN W, WU RR, VAN POELJE PD, ERION MD: Isolation of a family of organic anion transporters from human liver and kidney. Biochem. Biophys. Res. Commun. (2001) 283(2):417-422.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.283
, Issue.2
, pp. 417-422
-
-
SUN, W.1
WU, R.R.2
VAN POELJE, P.D.3
ERION, M.D.4
-
18
-
-
0036205460
-
Gene expression levels and immunolocalization of organic ion transporters in the human kidney
-
MOTOHASHI H, SAKURAI Y, SAITO H et al.: Gene expression levels and immunolocalization of organic ion transporters in the human kidney. J. Am. Soc. Nephrol. (2002) 13(4):866-874.
-
(2002)
J. Am. Soc. Nephrol
, vol.13
, Issue.4
, pp. 866-874
-
-
MOTOHASHI, H.1
SAKURAI, Y.2
SAITO, H.3
-
19
-
-
0242290366
-
Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux
-
BAKHIYA A, BAHN A, BURCKHARDT G, WOLFF N: Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux. Cell Pysiol. Biochem. (2003) 13(5):249-256.
-
(2003)
Cell Pysiol. Biochem
, vol.13
, Issue.5
, pp. 249-256
-
-
BAKHIYA, A.1
BAHN, A.2
BURCKHARDT, G.3
WOLFF, N.4
-
20
-
-
0035066252
-
Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters
-
DRESSER MJ, LEABMAN MK, GIACOMINI KM: Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters. J. Pharm. Sci. (2001) 90(4):397-421.
-
(2001)
J. Pharm. Sci
, vol.90
, Issue.4
, pp. 397-421
-
-
DRESSER, M.J.1
LEABMAN, M.K.2
GIACOMINI, K.M.3
-
21
-
-
0035843770
-
Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters
-
TAKEDA M, NARIKAWA S, HOSOYAMADA M et al.: Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. Eur. J. Pharmacol. (2001) 419(2-3):113-120.
-
(2001)
Eur. J. Pharmacol
, vol.419
, Issue.2-3
, pp. 113-120
-
-
TAKEDA, M.1
NARIKAWA, S.2
HOSOYAMADA, M.3
-
22
-
-
0037067159
-
Role of human organic anion transporter 4 in the transport of ochratoxin A
-
BABU E, TAKEDA M, NARIKAWA S et al.: Role of human organic anion transporter 4 in the transport of ochratoxin A. Biochim. Biophys. Acta (2002) 1590(1-3):64-75.
-
(2002)
Biochim. Biophys. Acta
, vol.1590
, Issue.1-3
, pp. 64-75
-
-
BABU, E.1
TAKEDA, M.2
NARIKAWA, S.3
-
23
-
-
0000518648
-
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta
-
CHA SH, SEKINE T, KUSUHARA H et al.: Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J. Biol. Chem. (2000) 275(6):4507-4512.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.6
, pp. 4507-4512
-
-
CHA, S.H.1
SEKINE, T.2
KUSUHARA, H.3
-
24
-
-
1842732504
-
Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules
-
EKARATANAWONG S, ANZAI N, JUTABHA P et al.: Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. J. Pharmacol. Sci. (2004) 94(3):297-304.
-
(2004)
J. Pharmacol. Sci
, vol.94
, Issue.3
, pp. 297-304
-
-
EKARATANAWONG, S.1
ANZAI, N.2
JUTABHA, P.3
-
25
-
-
1242272736
-
Organic anion transporting polypeptides of the OATP/SLC21 family: Phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties
-
HAGENBUCH B, MEIER PJ: Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch. (2004) 447(5):653-665.
-
(2004)
Pflugers Arch
, vol.447
, Issue.5
, pp. 653-665
-
-
HAGENBUCH, B.1
MEIER, P.J.2
-
26
-
-
0037427972
-
The superfamily of organic anion transporting polypeptides
-
HAGENBUCH B, MEIER PJ: The superfamily of organic anion transporting polypeptides. Biochim. Biophys. Acta (2003) 1609(1):1-18.
-
(2003)
Biochim. Biophys. Acta
, vol.1609
, Issue.1
, pp. 1-18
-
-
HAGENBUCH, B.1
MEIER, P.J.2
-
27
-
-
0034709561
-
Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family
-
TAMAI I, NEZU J, UCHINO H et al.: Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. Biochem. Biophys. Res. Commun. (2000) 273(1):251-260.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.273
, Issue.1
, pp. 251-260
-
-
TAMAI, I.1
NEZU, J.2
UCHINO, H.3
-
28
-
-
12144288563
-
Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney
-
MIKKAICHI T, SUZUKI T, ONOGAWA T et al.: Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc. Natl. Acad. Sci. USA (2004) 101(10):3569-3574.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.10
, pp. 3569-3574
-
-
MIKKAICHI, T.1
SUZUKI, T.2
ONOGAWA, T.3
-
29
-
-
26444539011
-
Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions
-
VAN DE WATER FM, MASEREEUW R, RUSSEL FG: Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions. Drug Metab. Rev. (2005) 37(3):443-471.
-
(2005)
Drug Metab. Rev
, vol.37
, Issue.3
, pp. 443-471
-
-
VAN DE WATER, F.M.1
MASEREEUW, R.2
RUSSEL, F.G.3
-
30
-
-
0036186107
-
The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: Putative efflux pump for urinary cAMP and cGMP
-
VAN AUBEL RA, SMEETS PH, PETERS JG, BINDELS RJ, RUSSEL FG: The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. J. Am. Soc. Nephrol. (2002) 13(3):595-603.
-
(2002)
J. Am. Soc. Nephrol
, vol.13
, Issue.3
, pp. 595-603
-
-
VAN AUBEL, R.A.1
SMEETS, P.H.2
PETERS, J.G.3
BINDELS, R.J.4
RUSSEL, F.G.5
-
31
-
-
0033032730
-
Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma
-
SCHAUB TP, KARTENBECK J, KONIG J et al.: Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma. J. Am. Soc. Nephrol. (1999) 10(6):1159-1169.
-
(1999)
J. Am. Soc. Nephrol
, vol.10
, Issue.6
, pp. 1159-1169
-
-
SCHAUB, T.P.1
KARTENBECK, J.2
KONIG, J.3
-
32
-
-
12144269640
-
Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter
-
SMEETS PH, VAN AUBEL RA, WOUTERSE AC, VAN DEN HEUVEL JJ, RUSSEL FG: Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter. J. Am. Soc. Nephrol. (2004) 15(11):2828-2835.
-
(2004)
J. Am. Soc. Nephrol
, vol.15
, Issue.11
, pp. 2828-2835
-
-
SMEETS, P.H.1
VAN AUBEL, R.A.2
WOUTERSE, A.C.3
VAN DEN HEUVEL, J.J.4
RUSSEL, F.G.5
-
33
-
-
12144257103
-
Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
-
VAN AUBEL RA, SMEETS PH, VAN DEN HEUVEL JJ, RUSSEL FG: Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am. J. Physiol. Renal Physiol. (2005) 288(2):F327-F333.
-
(2005)
Am. J. Physiol. Renal Physiol
, vol.288
, Issue.2
-
-
VAN AUBEL RA, S.P.1
VAN DEN HEUVEL JJ, R.F.2
-
34
-
-
1242295185
-
The SLC22 drug transporter family
-
KOEPSELL H, ENDOU H: The SLC22 drug transporter family. Pflugers Arch. (2004) 447(5):666-676.
-
(2004)
Pflugers Arch
, vol.447
, Issue.5
, pp. 666-676
-
-
KOEPSELL, H.1
ENDOU, H.2
-
35
-
-
33645220096
-
Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants
-
FUJITA T, URBAN TJ, LEABMAN MK, FUJITA K, GIACOMINI KM: Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants. J. Pharm. Sci. (2006) 95(1):25-36.
-
(2006)
J. Pharm. Sci
, vol.95
, Issue.1
, pp. 25-36
-
-
FUJITA, T.1
URBAN, T.J.2
LEABMAN, M.K.3
FUJITA, K.4
GIACOMINI, K.M.5
-
36
-
-
0033829943
-
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney
-
WU X, HUANG W, GANAPATHY ME et al.: Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney. Am. J. Physiol. Renal Physiol. (2000) 279(3):F449-F458.
-
(2000)
Am. J. Physiol. Renal Physiol
, vol.279
, Issue.3
-
-
WU, X.1
HUANG, W.2
GANAPATHY, M.E.3
-
37
-
-
0035815991
-
+)-coupled transport of L-carnitine via high-affinity carnitine transporter OCTN2 and its subcellular localization in kidney
-
+)-coupled transport of L-carnitine via high-affinity carnitine transporter OCTN2 and its subcellular localization in kidney. Biochim. Biophys. Acta (2001) 1512(2):273-284.
-
(2001)
Biochim. Biophys. Acta
, vol.1512
, Issue.2
, pp. 273-284
-
-
TAMAI, I.1
CHINA, K.2
SAI, Y.3
-
38
-
-
0345974472
-
Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations
-
TAMAI I, NAKANISHI T, KOBAYASHI D et al.: Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations. Mol. Pharm. (2004) 1(1):57-66.
-
(2004)
Mol. Pharm
, vol.1
, Issue.1
, pp. 57-66
-
-
TAMAI, I.1
NAKANISHI, T.2
KOBAYASHI, D.3
-
39
-
-
0032935034
-
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations
-
YABUUCHI H, TAMAI I, NEZU J et al.: Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. J. Pharmacol. Exp. Ther. (1999) 289(2):768-773.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.289
, Issue.2
, pp. 768-773
-
-
YABUUCHI, H.1
TAMAI, I.2
NEZU, J.3
-
41
-
-
0032493741
-
Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2
-
TAMAI I, OHASHI R, NEZU J et al.: Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2. J. Biol. Chem. (1998) 273(32):20378-20382.
-
(1998)
J. Biol. Chem
, vol.273
, Issue.32
, pp. 20378-20382
-
-
TAMAI, I.1
OHASHI, R.2
NEZU, J.3
-
42
-
-
0032767691
-
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter
-
WU X, HUANG W, PRASAD PD et al.: Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter. J. Pharmacol. Exp. Ther. (1999) 290(3):1482-1492.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.290
, Issue.3
, pp. 1482-1492
-
-
WU, X.1
HUANG, W.2
PRASAD, P.D.3
-
43
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
AMBUDKAR SV, DEY S, HRYCYNA CA et al.: Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Ann. Rev. Pharmacol. Toxicol. (1999) 39:361-398.
-
(1999)
Ann. Rev. Pharmacol. Toxicol
, vol.39
, pp. 361-398
-
-
AMBUDKAR, S.V.1
DEY, S.2
HRYCYNA, C.A.3
-
44
-
-
0037229942
-
Role of P-glycoprotein in pharmacokinetics: Clinical implications
-
LIN JH, YAMAZAKI M: Role of P-glycoprotein in pharmacokinetics: clinical implications. Clin. Pharmacokinet. (2003) 42(1):59-98.
-
(2003)
Clin. Pharmacokinet
, vol.42
, Issue.1
, pp. 59-98
-
-
LIN, J.H.1
YAMAZAKI, M.2
-
45
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
THIEBAUT F, TSURUO T, HAMADA H et al.: Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad. Sci. USA (1987) 84(21):7735-7738.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, Issue.21
, pp. 7735-7738
-
-
THIEBAUT, F.1
TSURUO, T.2
HAMADA, H.3
-
46
-
-
1242272750
-
The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology
-
DANIEL H, KOTTRA G: The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology. Pflugers Arch. (2004) 447(5):610-618.
-
(2004)
Pflugers Arch
, vol.447
, Issue.5
, pp. 610-618
-
-
DANIEL, H.1
KOTTRA, G.2
-
47
-
-
0032967296
-
Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney
-
SHEN H, SMITH DE, YANG T et al.: Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney. Am. J. Physiol. (1999) 276(5 Pt 2):F658-F665.
-
(1999)
Am. J. Physiol
, vol.276
, Issue.5 PART 2
-
-
SHEN, H.1
SMITH, D.E.2
YANG, T.3
-
48
-
-
33644849472
-
Cytosolic COOH terminus of the peptide transporter PEPT2 is involved in apical membrane localization of the protein
-
KLAPPER M, DANIEL H, DORING F: Cytosolic COOH terminus of the peptide transporter PEPT2 is involved in apical membrane localization of the protein. Am. J. Physiol. Cell Physiol. (2006) 290(2):C472-C483.
-
(2006)
Am. J. Physiol. Cell Physiol
, vol.290
, Issue.2
-
-
KLAPPER, M.1
DANIEL, H.2
DORING, F.3
-
49
-
-
33645101081
-
Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters
-
LI M, ANDERSON GD, PHILLIPS BR et al.: Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metab. Dispos. (2006) 34(4):547-555.
-
(2006)
Drug Metab. Dispos
, vol.34
, Issue.4
, pp. 547-555
-
-
LI, M.1
ANDERSON, G.D.2
PHILLIPS, B.R.3
-
50
-
-
0025868537
-
Dose-dependent absorption and elimination of cefadroxil in man
-
GARRIGUES TM, MARTIN U, PERIS-RIBERA JE, PRESCOTT LF: Dose-dependent absorption and elimination of cefadroxil in man. Eur. J. Clin. Pharmacol. (1991) 41(2):179-183.
-
(1991)
Eur. J. Clin. Pharmacol
, vol.41
, Issue.2
, pp. 179-183
-
-
GARRIGUES, T.M.1
MARTIN, U.2
PERIS-RIBERA, J.E.3
PRESCOTT, L.F.4
-
52
-
-
28444444126
-
Effects of renal failure on drug transport and metabolism
-
SUN H, FRASSETTO L, BENET LZ: Effects of renal failure on drug transport and metabolism. Pharmacol. Ther. (2006) 109(1-2):1-11.
-
(2006)
Pharmacol. Ther
, vol.109
, Issue.1-2
, pp. 1-11
-
-
SUN, H.1
FRASSETTO, L.2
BENET, L.Z.3
-
53
-
-
0017169928
-
Pharmacokinetics of the penicillins in man
-
BARZA M, WEINSTEIN L: Pharmacokinetics of the penicillins in man. Clin. Pharmacokinet. (1976) 1(4):297-308.
-
(1976)
Clin. Pharmacokinet
, vol.1
, Issue.4
, pp. 297-308
-
-
BARZA, M.1
WEINSTEIN, L.2
-
54
-
-
0001579719
-
On the mechanism of action of probenecid on renal tubular secretion
-
WEINER IM, WASHINGTON JA 2nd, MUDGE GH: On the mechanism of action of probenecid on renal tubular secretion. Bull. Johns Hopkins Hosp. (1960) 106:333-346.
-
(1960)
Bull. Johns Hopkins Hosp
, vol.106
, pp. 333-346
-
-
WEINER, I.M.1
WASHINGTON, J.A.2
MUDGE, G.H.3
-
55
-
-
0029846479
-
Renal transport of drugs: Specificity and molecular mechanisms
-
SOMOGYI A: Renal transport of drugs: specificity and molecular mechanisms. Clin. Exp. Pharmacol. Physiol. (1996) 23(10-11):986-989.
-
(1996)
Clin. Exp. Pharmacol. Physiol
, vol.23
, Issue.10-11
, pp. 986-989
-
-
SOMOGYI, A.1
-
57
-
-
0027417835
-
Cephalosporin-probenecid drug interactions
-
BROWN GR: Cephalosporin-probenecid drug interactions. Clin. Pharmacokinet. (1993) 24(4):289-300.
-
(1993)
Clin. Pharmacokinet
, vol.24
, Issue.4
, pp. 289-300
-
-
BROWN, G.R.1
-
59
-
-
0036260663
-
Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors
-
ENOMOTO A, TAKEDA M, SHIMODA M et al.: Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. J. Pharmacol. Exp. Ther. (2002) 301(3):797-802.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.301
, Issue.3
, pp. 797-802
-
-
ENOMOTO, A.1
TAKEDA, M.2
SHIMODA, M.3
-
61
-
-
0018765196
-
Clinical pharmacological studies of amoxycillin: Effect of probenecid
-
BARBHAIYA R, THIN RN, TURNER P, WADSWORTH J: Clinical pharmacological studies of amoxycillin: effect of probenecid. Br. J. Vener. Dis. (1979) 55(3):211-213.
-
(1979)
Br. J. Vener. Dis
, vol.55
, Issue.3
, pp. 211-213
-
-
BARBHAIYA, R.1
THIN, R.N.2
TURNER, P.3
WADSWORTH, J.4
-
62
-
-
0027171710
-
Effect of probenecid on cefazolin serum concentrations
-
BROWN G, ZEMCOV SJ, CLARKE AM: Effect of probenecid on cefazolin serum concentrations. J. Antimicrob. Chemother. (1993) 31(6):1009-1011.
-
(1993)
J. Antimicrob. Chemother
, vol.31
, Issue.6
, pp. 1009-1011
-
-
BROWN, G.1
ZEMCOV, S.J.2
CLARKE, A.M.3
-
63
-
-
0015663986
-
Pharmacodynamics of cefazolin in the presence of normal and impaired renal function
-
REIN MF, WESTERVELT FB, SANDE MA: Pharmacodynamics of cefazolin in the presence of normal and impaired renal function. Antimicrob. Agents Chemother. (1973) 4(3):366-371.
-
(1973)
Antimicrob. Agents Chemother
, vol.4
, Issue.3
, pp. 366-371
-
-
REIN, M.F.1
WESTERVELT, F.B.2
SANDE, M.A.3
-
64
-
-
0037406327
-
Effect of chronic probenecid therapy on cefazolin serum concentrations
-
SPINA SP, DILLON EC Jr: Effect of chronic probenecid therapy on cefazolin serum concentrations. Ann. Pharmacother. (2003) 37(5):621-624.
-
(2003)
Ann. Pharmacother
, vol.37
, Issue.5
, pp. 621-624
-
-
SPINA, S.P.1
DILLON Jr, E.C.2
-
65
-
-
1642539149
-
Expression levels of renal organic anion transporters (OATs) and their correlation with anionic drug excretion in patients with renal diseases
-
SAKURAI Y, MOTOHASHI H, UEO H et al.: Expression levels of renal organic anion transporters (OATs) and their correlation with anionic drug excretion in patients with renal diseases. Pharm. Res. (2004) 21(1):61-67.
-
(2004)
Pharm. Res
, vol.21
, Issue.1
, pp. 61-67
-
-
SAKURAI, Y.1
MOTOHASHI, H.2
UEO, H.3
-
66
-
-
18344371636
-
Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: In comparison with rOAT1
-
JUNG KY, TAKEDA M, SHIMODA M et al.: Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1. Life Sci. (2002) 70(16):1861-1874.
-
(2002)
Life Sci
, vol.70
, Issue.16
, pp. 1861-1874
-
-
JUNG, K.Y.1
TAKEDA, M.2
SHIMODA, M.3
-
67
-
-
24344461838
-
Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1
-
UEO H, MOTOHASHI H, KATSURA T, INUI K: Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1. Biochem. Pharmacol. (2005) 70(7):1104-1113.
-
(2005)
Biochem. Pharmacol
, vol.70
, Issue.7
, pp. 1104-1113
-
-
UEO, H.1
MOTOHASHI, H.2
KATSURA, T.3
INUI, K.4
-
68
-
-
0029000871
-
Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients
-
CUNDY KC, PETTY BG, FLAHERTY J et al.: Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients. Antimicrob. Agents Chemother. (1995) 39(6):1247-1252.
-
(1995)
Antimicrob. Agents Chemother
, vol.39
, Issue.6
, pp. 1247-1252
-
-
CUNDY, K.C.1
PETTY, B.G.2
FLAHERTY, J.3
-
69
-
-
0032997095
-
Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir
-
CUNDY KC: Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir. Clin. Pharmacokinet. (1999) 36(2):127-143.
-
(1999)
Clin. Pharmacokinet
, vol.36
, Issue.2
, pp. 127-143
-
-
CUNDY, K.C.1
-
70
-
-
0032856603
-
The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1
-
CIHLAR T, LIN DC, PRITCHARD JB et al.: The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1. Mol. Pharmacol. (1999) 56(3):570-580.
-
(1999)
Mol. Pharmacol
, vol.56
, Issue.3
, pp. 570-580
-
-
CIHLAR, T.1
LIN, D.C.2
PRITCHARD, J.B.3
-
71
-
-
0034008388
-
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1
-
HO ES, LIN DC, MENDEL DB, CIHLAR T: Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1. J. Am. Soc. Nephrol. (2000) 11(3):383-393.
-
(2000)
J. Am. Soc. Nephrol
, vol.11
, Issue.3
, pp. 383-393
-
-
HO, E.S.1
LIN, D.C.2
MENDEL, D.B.3
CIHLAR, T.4
-
72
-
-
0020325272
-
Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans
-
LASKIN OL, DE MIRANDA P, KING DH et al.: Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans. Antimicrob. Agents Chemother. (1982) 21(5):804-807.
-
(1982)
Antimicrob. Agents Chemother
, vol.21
, Issue.5
, pp. 804-807
-
-
LASKIN, O.L.1
DE MIRANDA, P.2
KING, D.H.3
-
73
-
-
0036146750
-
Multiple interactions of cimetidine and probenecid with valaciclovir and its metabolite acyclovir
-
DE BONY F, TOD M, BIDAULT R et al.: Multiple interactions of cimetidine and probenecid with valaciclovir and its metabolite acyclovir. Antimicrob. Agents Chemother. (2002) 46(2):458-463.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, Issue.2
, pp. 458-463
-
-
DE BONY, F.1
TOD, M.2
BIDAULT, R.3
-
74
-
-
0025061746
-
Probenecid inhibits the metabolic and renal clearances of zidovudine (AZT) in human volunteers
-
HEDAYA MA, ELMQUIST WF, SAWCHUK RJ: Probenecid inhibits the metabolic and renal clearances of zidovudine (AZT) in human volunteers. Pharm. Res. (1990) 7(4):411-417.
-
(1990)
Pharm. Res
, vol.7
, Issue.4
, pp. 411-417
-
-
HEDAYA, M.A.1
ELMQUIST, W.F.2
SAWCHUK, R.J.3
-
75
-
-
0036175142
-
Human organic anion transporters and human organic cation transporters mediate renal antiviral transport
-
TAKEDA M, KHAMDANG S, NARIKAWA S et al.: Human organic anion transporters and human organic cation transporters mediate renal antiviral transport. J. Pharmacol. Exp. Ther. (2002) 300(3):918-924.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.300
, Issue.3
, pp. 918-924
-
-
TAKEDA, M.1
KHAMDANG, S.2
NARIKAWA, S.3
-
76
-
-
0022601216
-
Competition of organic anions for furosemide and p-aminohippurate secretion in the rabbit
-
BIDIVILLE J, ROCH-RAMEL F: Competition of organic anions for furosemide and p-aminohippurate secretion in the rabbit. J. Pharmacol. Exp. Ther. (1986) 237(2):636-643.
-
(1986)
J. Pharmacol. Exp. Ther
, vol.237
, Issue.2
, pp. 636-643
-
-
BIDIVILLE, J.1
ROCH-RAMEL, F.2
-
77
-
-
0019466698
-
Effect of bumetanide on p-aminohippurate transport in renal cortical slices
-
GEMBA M, TANIGUCHI M, MATSUSHIMA Y: Effect of bumetanide on p-aminohippurate transport in renal cortical slices. J. Pharmacobiodyn. (1981) 4(3):162-166.
-
(1981)
J. Pharmacobiodyn
, vol.4
, Issue.3
, pp. 162-166
-
-
GEMBA, M.1
TANIGUCHI, M.2
MATSUSHIMA, Y.3
-
78
-
-
0018725963
-
Pharmacodynamic analysis of the furosemide-probenecid interaction in man
-
CHENNAVASIN P, SEIWELL R, BRATER DC, LIANG WM: Pharmacodynamic analysis of the furosemide-probenecid interaction in man. Kidney Int. (1979) 16(2):187-195.
-
(1979)
Kidney Int
, vol.16
, Issue.2
, pp. 187-195
-
-
CHENNAVASIN, P.1
SEIWELL, R.2
BRATER, D.C.3
LIANG, W.M.4
-
79
-
-
0013800021
-
Influence of probenecid and alterations in acid-base balance of the saluretic activity of furosemide
-
HOOK JB, WILLIAMSON HE: Influence of probenecid and alterations in acid-base balance of the saluretic activity of furosemide. J. Pharmacol. Exp. Ther. (1965) 149(3):404-408.
-
(1965)
J. Pharmacol. Exp. Ther
, vol.149
, Issue.3
, pp. 404-408
-
-
HOOK, J.B.1
WILLIAMSON, H.E.2
-
80
-
-
0019865608
-
Saturable kinetics of intravenous chlorothiazide in the rhesus monkey
-
GUSTAFSON JH, BENET LZ: Saturable kinetics of intravenous chlorothiazide in the rhesus monkey. J. Pharmacokinet. Biopharm. (1981) 9(4):461-476.
-
(1981)
J. Pharmacokinet. Biopharm
, vol.9
, Issue.4
, pp. 461-476
-
-
GUSTAFSON, J.H.1
BENET, L.Z.2
-
81
-
-
0031050381
-
Saturable accumulation and diuretic activity of hydrochlorothiazide in the isolated perfused rat kidney
-
MASEREEUW R, MOONS WM, RUSSEL FG: Saturable accumulation and diuretic activity of hydrochlorothiazide in the isolated perfused rat kidney. Pharmacology (1997) 54(1):33-42.
-
(1997)
Pharmacology
, vol.54
, Issue.1
, pp. 33-42
-
-
MASEREEUW, R.1
MOONS, W.M.2
RUSSEL, F.G.3
-
82
-
-
0029020208
-
Probenecid inhibits the renal clearance of frusemide and its acyl glucuronide
-
VREE TB, VAN DEN BIGGELAAR-MARTEA M, VERWEY-VAN WISSEN CP: Probenecid inhibits the renal clearance of frusemide and its acyl glucuronide. Br. J. Clin. Pharmacol. (1995) 39(6):692-695.
-
(1995)
Br. J. Clin. Pharmacol
, vol.39
, Issue.6
, pp. 692-695
-
-
VREE, T.B.1
VAN DEN BIGGELAAR-MARTEA, M.2
VERWEY-VAN, W.C.3
-
83
-
-
0018886475
-
Renal tubular secretion and effects of furosemide
-
ODLIND B, BEERMANN B: Renal tubular secretion and effects of furosemide. Clin. Pharmacol. Ther. (1980) 27(6):784-790.
-
(1980)
Clin. Pharmacol. Ther
, vol.27
, Issue.6
, pp. 784-790
-
-
ODLIND, B.1
BEERMANN, B.2
-
84
-
-
10744233574
-
Interactions of human organic anion transporters with diuretics
-
HASANNEJAD H, TAKEDA M, TAKI K et al.: Interactions of human organic anion transporters with diuretics. J. Pharmacol. Exp. Ther. (2004) 308(3):1021-1029.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.308
, Issue.3
, pp. 1021-1029
-
-
HASANNEJAD, H.1
TAKEDA, M.2
TAKI, K.3
-
85
-
-
33646165531
-
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knockout mice
-
ERALY SA, VALLON V, VAUGHN DA et al.: Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knockout mice. J. Biol. Chem. (2006) 281(8):5072-5083.
-
(2006)
J. Biol. Chem
, vol.281
, Issue.8
, pp. 5072-5083
-
-
ERALY, S.A.1
VALLON, V.2
VAUGHN, D.A.3
-
86
-
-
0028792273
-
The effects of nonsteroidal antiinflammatory drugs on methotrexate (MTX) pharmacokinetics: Impairment of renal clearance of MTX at weekly maintenance doses but not at 7.5 mg
-
KREMER JM, HAMILTON RA: The effects of nonsteroidal antiinflammatory drugs on methotrexate (MTX) pharmacokinetics: impairment of renal clearance of MTX at weekly maintenance doses but not at 7.5 mg. J. Rheumatol. (1995) 22(11):2072-2077.
-
(1995)
J. Rheumatol
, vol.22
, Issue.11
, pp. 2072-2077
-
-
KREMER, J.M.1
HAMILTON, R.A.2
-
87
-
-
0014610105
-
The effect of organic acids on renal clearance of methotrexate in man
-
LIEGLER DG, HENDERSON ES, HAHN MA, OLIVERIO VT: The effect of organic acids on renal clearance of methotrexate in man. Clin. Pharmacol. Ther. (1969) 10(6):849-857.
-
(1969)
Clin. Pharmacol. Ther
, vol.10
, Issue.6
, pp. 849-857
-
-
LIEGLER, D.G.1
HENDERSON, E.S.2
HAHN, M.A.3
OLIVERIO, V.T.4
-
88
-
-
0026570125
-
Methotrexate and nonsteroidal antiinflammatory drug interactions
-
FRENIA ML, LONG KS: Methotrexate and nonsteroidal antiinflammatory drug interactions. Ann. Pharmacother. (1992) 26(2):234-237.
-
(1992)
Ann. Pharmacother
, vol.26
, Issue.2
, pp. 234-237
-
-
FRENIA, M.L.1
LONG, K.S.2
-
89
-
-
0022613399
-
Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen
-
THYSSA, MILANO G, KUBAR J, NAMER M, SCHNEIDER M: Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen. Lancet (1986) 1(8475):256-258.
-
(1986)
Lancet
, vol.1
, Issue.8475
, pp. 256-258
-
-
THYSSA, M.G.1
KUBAR, J.2
NAMER, M.3
SCHNEIDER, M.4
-
90
-
-
0036076780
-
Characterization of methotrexate transport and its drug interactions with human organic anion transporters
-
TAKEDA M, KHAMDANG S, NARIKAWA S et al.: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J. Pharmacol. Exp. Ther. (2002) 302(2):666-671.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.302
, Issue.2
, pp. 666-671
-
-
TAKEDA, M.1
KHAMDANG, S.2
NARIKAWA, S.3
-
91
-
-
0033152212
-
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2
-
HOOIJBERG JH, BROXTERMAN HJ, KOOL M et al.: Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. Cancer Res. (1999) 59(11):2532-2535.
-
(1999)
Cancer Res
, vol.59
, Issue.11
, pp. 2532-2535
-
-
HOOIJBERG, J.H.1
BROXTERMAN, H.J.2
KOOL, M.3
-
92
-
-
0036827850
-
Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs
-
KHAMDANG S, TAKEDA M, NOSHIRO R et al.: Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs. J. Pharmacol. Exp. Ther. (2002) 303(2):534-539.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.303
, Issue.2
, pp. 534-539
-
-
KHAMDANG, S.1
TAKEDA, M.2
NOSHIRO, R.3
-
93
-
-
0020488482
-
Cimetidine reduces procainamide elimination
-
SOMOGYI A, HEINZOW B: Cimetidine reduces procainamide elimination. N. Engl. J. Med. (1982) 307(17):1080.
-
(1982)
N. Engl. J. Med
, vol.307
, Issue.17
, pp. 1080
-
-
SOMOGYI, A.1
HEINZOW, B.2
-
94
-
-
0020510972
-
Clinical pharmacokinetics of cimetidine
-
SOMOGYI A, GUGLER R: Clinical pharmacokinetics of cimetidine. Clin. Pharmacokinet. (1983) 8(6):463-495.
-
(1983)
Clin. Pharmacokinet
, vol.8
, Issue.6
, pp. 463-495
-
-
SOMOGYI, A.1
GUGLER, R.2
-
95
-
-
0020635466
-
Cimetidine-procainamide pharmacokinetic interaction in man: Evidence of competition for tubular secretion of basic drugs
-
SOMOGYI A, MCLEAN A, HEINZOW B: Cimetidine-procainamide pharmacokinetic interaction in man: evidence of competition for tubular secretion of basic drugs. Eur. J. Clin. Pharmacol. (1983) 25(3):339-345.
-
(1983)
Eur. J. Clin. Pharmacol
, vol.25
, Issue.3
, pp. 339-345
-
-
SOMOGYI, A.1
MCLEAN, A.2
HEINZOW, B.3
-
96
-
-
0023248835
-
Pharmacokinetic interactions of cimetidine 1987
-
SOMOGYI A, MUIRHEAD M: Pharmacokinetic interactions of cimetidine 1987. Clin. Pharmacokinet. (1987) 12(5):321-366.
-
(1987)
Clin. Pharmacokinet
, vol.12
, Issue.5
, pp. 321-366
-
-
SOMOGYI, A.1
MUIRHEAD, M.2
-
97
-
-
25644452793
-
2 receptor antagonists by rat and human renal organic anion and cation transporters
-
2 receptor antagonists by rat and human renal organic anion and cation transporters. J. Pharmacol. Exp. Ther. (2005) 315(1):337-345.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.315
, Issue.1
, pp. 337-345
-
-
TAHARA, H.1
KUSUHARA, H.2
ENDOU, H.3
-
98
-
-
7444254904
-
Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A)
-
MOTOHASHI H, UWAI Y, HIRAMOTO K, OKUDA M, INUI K: Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A). Eur. J. Pharmacol. (2004) 503(1-3):25-30.
-
(2004)
Eur. J. Pharmacol
, vol.503
, Issue.1-3
, pp. 25-30
-
-
MOTOHASHI, H.1
UWAI, Y.2
HIRAMOTO, K.3
OKUDA, M.4
INUI, K.5
-
99
-
-
6344240973
-
Relative contribution of OAT and OCT transporters to organic electrolyte transport in rabbit proximal tubule
-
ZHANG X, GROVES CE, BAHN A et al.: Relative contribution of OAT and OCT transporters to organic electrolyte transport in rabbit proximal tubule. Am. J. Physiol. Renal Physiol. (2004) 287(5):F999-F1010.
-
(2004)
Am. J. Physiol. Renal Physiol
, vol.287
, Issue.5
-
-
ZHANG, X.1
GROVES, C.E.2
BAHN, A.3
-
100
-
-
0023204364
-
Reduction of metformin renal tubular secretion by cimetidine in man
-
SOMOGYI A, STOCKLEY C, KEAL J, ROLAN P, BOCHNER F: Reduction of metformin renal tubular secretion by cimetidine in man. Br. J. Clin. Pharmacol. (1987) 23(5):545-551.
-
(1987)
Br. J. Clin. Pharmacol
, vol.23
, Issue.5
, pp. 545-551
-
-
SOMOGYI, A.1
STOCKLEY, C.2
KEAL, J.3
ROLAN, P.4
BOCHNER, F.5
-
101
-
-
0036689433
-
Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2)
-
DRESSER MJ, XIAO G, LEABMAN MK, GRAV AT, GIACOMINI KM: Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2). Pharm. Res. (2002) 19(8):1244-1247.
-
(2002)
Pharm. Res
, vol.19
, Issue.8
, pp. 1244-1247
-
-
DRESSER, M.J.1
XIAO, G.2
LEABMAN, M.K.3
GRAV, A.T.4
GIACOMINI, K.M.5
-
102
-
-
16844384592
-
Metformin transport by renal basolateral organic cation transporter hOCT2
-
KIMURA N, OKUDA M, INUI K: Metformin transport by renal basolateral organic cation transporter hOCT2. Pharm. Res. (2005) 22(2):255-259.
-
(2005)
Pharm. Res
, vol.22
, Issue.2
, pp. 255-259
-
-
KIMURA, N.1
OKUDA, M.2
INUI, K.3
-
103
-
-
0024546822
-
Renal tubular secretion of amiloride and its inhibition by cimetidine in humans and in an animal model
-
SOMOGYI AA, HOVENS CM, MUIRHEAD MR, BOCHNER F: Renal tubular secretion of amiloride and its inhibition by cimetidine in humans and in an animal model. Drug Metab. Dispos. (1989) 17(2):190-196.
-
(1989)
Drug Metab. Dispos
, vol.17
, Issue.2
, pp. 190-196
-
-
SOMOGYI, A.A.1
HOVENS, C.M.2
MUIRHEAD, M.R.3
BOCHNER, F.4
-
104
-
-
33744824064
-
Characterization of regulatory mechanisms and states of human organic cation transporter 2
-
BIERMANN J, LANG D, GORBOULEV V et al.: Characterization of regulatory mechanisms and states of human organic cation transporter 2. Am. J. Physiol. Cell Physiol. (2006) 290(6):C1521-C1531.
-
(2006)
Am. J. Physiol. Cell Physiol
, vol.290
, Issue.6
-
-
BIERMANN, J.1
LANG, D.2
GORBOULEV, V.3
-
105
-
-
0026606632
-
Stereoselective inhibition of pindolol renal clearance by cimetidine in humans
-
SOMOGYI AA, BOCHNER F, SALLUSTIO BC: Stereoselective inhibition of pindolol renal clearance by cimetidine in humans. Clin. Pharmacol. Ther. (1992) 51(4):379-387.
-
(1992)
Clin. Pharmacol. Ther
, vol.51
, Issue.4
, pp. 379-387
-
-
SOMOGYI, A.A.1
BOCHNER, F.2
SALLUSTIO, B.C.3
-
106
-
-
0023796147
-
Trimethoprim alters the disposition of procainamide and N-acetylprocainamide
-
KOSOGLOU T, ROCCI ML Jr, VLASSES PH: Trimethoprim alters the disposition of procainamide and N-acetylprocainamide. Clin. Pharmacol. Ther. (1988) 44(4):467-477.
-
(1988)
Clin. Pharmacol. Ther
, vol.44
, Issue.4
, pp. 467-477
-
-
KOSOGLOU, T.1
ROCCI Jr, M.L.2
VLASSES, P.H.3
-
107
-
-
0024316504
-
Trimethoprim inhibition of the renal clearance of procainamide and N-acetylprocainamide
-
VLASSES PH, KOSOGLOU T, CHASE SL et al.: Trimethoprim inhibition of the renal clearance of procainamide and N-acetylprocainamide. Arch. Intent. Med. (1989) 149(6):1350-1353.
-
(1989)
Arch. Intent. Med
, vol.149
, Issue.6
, pp. 1350-1353
-
-
VLASSES, P.H.1
KOSOGLOU, T.2
CHASE, S.L.3
-
108
-
-
0026096151
-
Pharmacokinetics of digoxin and main metabolites/derivatives in healthy humans
-
HINDERLING PH, HARTMANN D: Pharmacokinetics of digoxin and main metabolites/derivatives in healthy humans. Ther. Drug Monit. (1991) 13(5):381-401.
-
(1991)
Ther. Drug Monit
, vol.13
, Issue.5
, pp. 381-401
-
-
HINDERLING, P.H.1
HARTMANN, D.2
-
109
-
-
0032705762
-
Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice
-
KAWAHARA M, SAKATA A, MIYASHITA T, TAMAI I, TSUJI A: Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice. J. Pharm. Sci. (1999) 88(12): 1281-1287.
-
(1999)
J. Pharm. Sci
, vol.88
, Issue.12
, pp. 1281-1287
-
-
KAWAHARA, M.1
SAKATA, A.2
MIYASHITA, T.3
TAMAI, I.4
TSUJI, A.5
-
110
-
-
0034520267
-
St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4
-
DURR D, STIEGER B, KULLAK-UBLICK GA et al.: St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4. Clin. Pharmacol. Ther. (2000) 68(6):598-604.
-
(2000)
Clin. Pharmacol. Ther
, vol.68
, Issue.6
, pp. 598-604
-
-
DURR, D.1
STIEGER, B.2
KULLAK-UBLICK, G.A.3
-
111
-
-
0027102401
-
The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin
-
DELANNOY IA, SILVERMAN M: The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. Biochem. Biophys. Res. Commun. (1992) 189(1):551-557.
-
(1992)
Biochem. Biophys. Res. Commun
, vol.189
, Issue.1
, pp. 551-557
-
-
DELANNOY, I.A.1
SILVERMAN, M.2
-
112
-
-
0018750834
-
Digoxin-quinidine interaction. Pharmacokinetic evaluation
-
HAGER WD, FENSTER P, MAYERSOHN M et al.: Digoxin-quinidine interaction. Pharmacokinetic evaluation. N. Engl. J. Med. (1979) 300(22):1238-1241.
-
(1979)
N. Engl. J. Med
, vol.300
, Issue.22
, pp. 1238-1241
-
-
HAGER, W.D.1
FENSTER, P.2
MAYERSOHN, M.3
-
113
-
-
0025092259
-
Interactions in the renal and biliary elimination of digoxin: Stereoselective difference between quinine and quinidine
-
HEDMAN A, ANGELIN B, ARVIDSSON A, DAHLQVIST R, NILSSON B: Interactions in the renal and biliary elimination of digoxin: stereoselective difference between quinine and quinidine. Clin. Pharmacol. Ther. (1990) 47(1):20-26.
-
(1990)
Clin. Pharmacol. Ther
, vol.47
, Issue.1
, pp. 20-26
-
-
HEDMAN, A.1
ANGELIN, B.2
ARVIDSSON, A.3
DAHLQVIST, R.4
NILSSON, B.5
-
114
-
-
0021722205
-
Quinidine-induced changes in serum and skeletal muscle digoxin concentration; evidence of saturable binding of digoxin to skeletal muscle
-
JOGESTRAND T, SCHENCK-GUSTAFSSON K, NORDLANDER R, DAHLQVIST R: Quinidine-induced changes in serum and skeletal muscle digoxin concentration; evidence of saturable binding of digoxin to skeletal muscle. Eur. J. Clin. Pharmacol. (1984) 27(5):571-575.
-
(1984)
Eur. J. Clin. Pharmacol
, vol.27
, Issue.5
, pp. 571-575
-
-
JOGESTRAND, T.1
SCHENCK-GUSTAFSSON, K.2
NORDLANDER, R.3
DAHLQVIST, R.4
-
115
-
-
0020662364
-
Cardiac effects of treatment with quinidine and digoxin, alone and in combination
-
SCHENCK-GUSTAFSSON K, JOGESTRAND T, BRODIN LA, NORDLANDER R, DAHLQVIST R: Cardiac effects of treatment with quinidine and digoxin, alone and in combination. Am. J. Cardiol. (1983) 51(5):777-782.
-
(1983)
Am. J. Cardiol
, vol.51
, Issue.5
, pp. 777-782
-
-
SCHENCK-GUSTAFSSON, K.1
JOGESTRAND, T.2
BRODIN, L.A.3
NORDLANDER, R.4
DAHLQVIST, R.5
-
116
-
-
0026459449
-
Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1)
-
TANIGAWARA Y, OKAMURA N, HIRAI M et al.: Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1). J. Pharmacol. Exp. Ther. (1992) 263(2):840-845.
-
(1992)
J. Pharmacol. Exp. Ther
, vol.263
, Issue.2
, pp. 840-845
-
-
TANIGAWARA, Y.1
OKAMURA, N.2
HIRAI, M.3
-
117
-
-
0033514320
-
Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine
-
FROMM MF, KIM RB, STEIN CM, WILKINSON GR, RODEN DM: Inhibition of P-glycoprotein-mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine. Circulation (1999) 99(4):552-557.
-
(1999)
Circulation
, vol.99
, Issue.4
, pp. 552-557
-
-
FROMM, M.F.1
KIM, R.B.2
STEIN, C.M.3
WILKINSON, G.R.4
RODEN, D.M.5
-
118
-
-
3042568988
-
Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers
-
DING R, TAYROUZ Y, RIEDEL KD et al.: Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers. Clin. Pharmacol. Ther. (2004) 76(1):73-84.
-
(2004)
Clin. Pharmacol. Ther
, vol.76
, Issue.1
, pp. 73-84
-
-
DING, R.1
TAYROUZ, Y.2
RIEDEL, K.D.3
-
119
-
-
0032765899
-
Interactions of HIV protease inhibitors with ATP-dependent drug export proteins
-
GUTMANN H, FRICKER G, DREWE J, TOEROEK M, MILLER DS: Interactions of HIV protease inhibitors with ATP-dependent drug export proteins. Mol. Pharmacol. (1999) 56(2):383-389.
-
(1999)
Mol. Pharmacol
, vol.56
, Issue.2
, pp. 383-389
-
-
GUTMANN, H.1
FRICKER, G.2
DREWE, J.3
TOEROEK, M.4
MILLER, D.S.5
-
120
-
-
0033562673
-
HIV protease inhibitor ritonavir: A more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC-833
-
DREWE J, GUTMANN H, FRICKER G et al.: HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC-833. Biochem. Pharmacol. (1999) 57(10):1147-1152.
-
(1999)
Biochem. Pharmacol
, vol.57
, Issue.10
, pp. 1147-1152
-
-
DREWE, J.1
GUTMANN, H.2
FRICKER, G.3
-
121
-
-
0027455141
-
The mechanism of the verapamil-digoxin interaction in renal tubular cells (LLC-PK1)
-
ITO S, WOODLAND C, HARPER PA, KOREN G: The mechanism of the verapamil-digoxin interaction in renal tubular cells (LLC-PK1). Life Sci. (1993) 53(24):PL399-PL403.
-
(1993)
Life Sci
, vol.53
, Issue.24
-
-
ITO, S.1
WOODLAND, C.2
HARPER, P.A.3
KOREN, G.4
-
122
-
-
0032848316
-
P-glycoprotein system as a determinant of drug interactions: The case of digoxin-verapamil
-
VERSCHRAAGEN M, KOKS CH, SCHELLENS JH, BEIJNEN JH: P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil. Pharmacol. Res. (1999) 40(4):301-306.
-
(1999)
Pharmacol. Res
, vol.40
, Issue.4
, pp. 301-306
-
-
VERSCHRAAGEN, M.1
KOKS, C.H.2
SCHELLENS, J.H.3
BEIJNEN, J.H.4
-
123
-
-
0019412661
-
Digoxin-verapamil interaction
-
PEDERSEN KE, DORPH-PEDERSEN A, HVIDT S, KLITGAARD NA, NIELSEN-KUDSK F: Digoxin-verapamil interaction. Clin. Pharmacol. Ther. (1981) 30(3):311-316.
-
(1981)
Clin. Pharmacol. Ther
, vol.30
, Issue.3
, pp. 311-316
-
-
PEDERSEN, K.E.1
DORPH-PEDERSEN, A.2
HVIDT, S.3
KLITGAARD, N.A.4
NIELSEN-KUDSK, F.5
-
124
-
-
0027856015
-
Digoxin-cyclosporin A interaction: Modulation of the multidrug transporter P-glycoprotein in the kidney
-
OKAMURA N, HIRAI M, TANIGAWARA Y et al.: Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney. J. Pharmacol. Exp. Ther. (1993) 266(3):1614-1619.
-
(1993)
J. Pharmacol. Exp. Ther
, vol.266
, Issue.3
, pp. 1614-1619
-
-
OKAMURA, N.1
HIRAI, M.2
TANIGAWARA, Y.3
-
125
-
-
0031845356
-
Effect of clarithromycin on renal excretion of digoxin: Interaction with P-glycoprotein
-
WAKASUGI H, YANO I, ITO T et al.: Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein. Clin. Pharmacol. Ther. (1998) 64(1):123-128.
-
(1998)
Clin. Pharmacol. Ther
, vol.64
, Issue.1
, pp. 123-128
-
-
WAKASUGI, H.1
YANO, I.2
ITO, T.3
-
126
-
-
12344296912
-
Interactions between clarithromycin and digoxin in patients with end-stage renal disease
-
HIRATA S, IZUMI S, FURUKUBO T et al.: Interactions between clarithromycin and digoxin in patients with end-stage renal disease. Int. J. Clin. Pharmacol. Ther. (2005) 43(1):30-36.
-
(2005)
Int. J. Clin. Pharmacol. Ther
, vol.43
, Issue.1
, pp. 30-36
-
-
HIRATA, S.1
IZUMI, S.2
FURUKUBO, T.3
-
127
-
-
4544326030
-
Clarithromycin induced digoxin toxicity: Case report and review
-
KIRAN N, AZAM S, DHAKAM S: Clarithromycin induced digoxin toxicity: case report and review. J. Pak. Med. Assoc. (2004) 54(8):440-441.
-
(2004)
J. Pak. Med. Assoc
, vol.54
, Issue.8
, pp. 440-441
-
-
KIRAN, N.1
AZAM, S.2
DHAKAM, S.3
-
128
-
-
0038336620
-
Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction
-
RENGELSHAUSEN J, GOGGELMANN C, BURHENNE J et al.: Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction. Br. J. Clin. Pharmacol. (2003) 56(1):32-38.
-
(2003)
Br. J. Clin. Pharmacol
, vol.56
, Issue.1
, pp. 32-38
-
-
RENGELSHAUSEN, J.1
GOGGELMANN, C.2
BURHENNE, J.3
-
129
-
-
0034794892
-
Clarithromycin-induced digoxin toxicity: A case report and a review of the literature
-
XU H, RASHKOW A: Clarithromycin-induced digoxin toxicity: a case report and a review of the literature. Conn. Med. (2001) 65(9):527-529.
-
(2001)
Conn. Med
, vol.65
, Issue.9
, pp. 527-529
-
-
XU, H.1
RASHKOW, A.2
-
130
-
-
0030868579
-
The digoxin-propafenone interaction: Characterization of a mechanism using renal tubular cell monolayers
-
WOODLAND C, VERJEE Z, GIESBRECHT E, KOREN G, ITO S: The digoxin-propafenone interaction: characterization of a mechanism using renal tubular cell monolayers. J. Pharmacol. Exp. Ther. (1997) 283(1):39-45.
-
(1997)
J. Pharmacol. Exp. Ther
, vol.283
, Issue.1
, pp. 39-45
-
-
WOODLAND, C.1
VERJEE, Z.2
GIESBRECHT, E.3
KOREN, G.4
ITO, S.5
-
131
-
-
0031443240
-
Itraconazole decreases renal clearance of digoxin
-
JALAVA KM, PARTANEN J, NEUVONEN PJ: Itraconazole decreases renal clearance of digoxin. Ther. Drug Monit. (1997) 19(6):609-613.
-
(1997)
Ther. Drug Monit
, vol.19
, Issue.6
, pp. 609-613
-
-
JALAVA, K.M.1
PARTANEN, J.2
NEUVONEN, P.J.3
-
132
-
-
0031980141
-
A model for the prediction of digoxin-drug interactions at the renal tubular cell level
-
WOODLAND C, ITO S. KOREN G: A model for the prediction of digoxin-drug interactions at the renal tubular cell level. Ther. Drug Monit. (1998) 20(2):134-138.
-
(1998)
Ther. Drug Monit
, vol.20
, Issue.2
, pp. 134-138
-
-
WOODLAND, C.1
ITO, S.2
KOREN, G.3
-
133
-
-
20044374201
-
Characterisation of (R/S)-propafenone and its metabolites as substrates and inhibitors of P-glycoprotein
-
BACHMAKOV I, REKERSBRINK S, HOFMANN U, EICHELBAUM M, FROMM MF: Characterisation of (R/S)-propafenone and its metabolites as substrates and inhibitors of P-glycoprotein. Naunyn Schmiedebergs Arch. Pharmacol. (2005) 371(3):195-201.
-
(2005)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.371
, Issue.3
, pp. 195-201
-
-
BACHMAKOV, I.1
REKERSBRINK, S.2
HOFMANN, U.3
EICHELBAUM, M.4
FROMM, M.F.5
-
134
-
-
0345411341
-
P-glycoprotein and cytochrome P450 3A inhibition: Dissociation of inhibitory potencies
-
WANDEL C, KIM RB, KAJIJI S et al.: P-glycoprotein and cytochrome P450 3A inhibition: dissociation of inhibitory potencies. Cancer Res. (1999) 59(16):3944-3948.
-
(1999)
Cancer Res
, vol.59
, Issue.16
, pp. 3944-3948
-
-
WANDEL, C.1
KIM, R.B.2
KAJIJI, S.3
-
135
-
-
1542771649
-
Mechanisms of cefadroxil uptake in the choroid plexus: Studies in wild-type and PEPT2 knockout mice
-
OCHELTREE SM, SHEN H, HU Y et al.: Mechanisms of cefadroxil uptake in the choroid plexus: studies in wild-type and PEPT2 knockout mice. J. Pharmacol. Exp. Ther. (2004) 308(2):462-467.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.308
, Issue.2
, pp. 462-467
-
-
OCHELTREE, S.M.1
SHEN, H.2
HU, Y.3
-
136
-
-
0034825921
-
Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: Uptake and transport of fosinopril in cell cultures
-
SHU C, SHEN H, HOPFER U, SMITH DE: Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: uptake and transport of fosinopril in cell cultures. Drug Metab. Dispos. (2001) 29(10):1307-1315.
-
(2001)
Drug Metab. Dispos
, vol.29
, Issue.10
, pp. 1307-1315
-
-
SHU, C.1
SHEN, H.2
HOPFER, U.3
SMITH, D.E.4
-
137
-
-
22944433202
-
Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6)
-
BLEASBY K, HALL LA, PERRY JL, MOHRENWEISER HW, PRITCHARD JB: Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6). J. Pharmacol. Exp. Ther. (2005) 314(2):923-931.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.314
, Issue.2
, pp. 923-931
-
-
BLEASBY, K.1
HALL, L.A.2
PERRY, J.L.3
MOHRENWEISER, H.W.4
PRITCHARD, J.B.5
-
138
-
-
0036020986
-
Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function
-
LEABMAN MK, HUANG CC, KAWAMOTO M et al.: Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function. Pharmacogenetics (2002) 12(5):395-405.
-
(2002)
Pharmacogenetics
, vol.12
, Issue.5
, pp. 395-405
-
-
LEABMAN, M.K.1
HUANG, C.C.2
KAWAMOTO, M.3
-
139
-
-
33645743694
-
The human organic anion transporter 3 (OAT3; SLC22A8): Genetic variation and functional genomics
-
ERDMAN AR, MANGRAVITE LM, URBAN TJ et al.: The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics. Am. J. Physiol. Renal Physiol. (2006) 290(4):F905-F912.
-
(2006)
Am. J. Physiol. Renal Physiol
, vol.290
, Issue.4
-
-
ERDMAN, A.R.1
MANGRAVITE, L.M.2
URBAN, T.J.3
-
140
-
-
1642523162
-
Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
-
MARZOLINI C, PAUS E, BUCLIN T, KIM RB: Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. Clin. Pharmacol. Ther. (2004) 75(1):13-33.
-
(2004)
Clin. Pharmacol. Ther
, vol.75
, Issue.1
, pp. 13-33
-
-
MARZOLINI, C.1
PAUS, E.2
BUCLIN, T.3
KIM, R.B.4
-
141
-
-
27544453846
-
Interaction of organic cations with a newly identified plasma membrane monoamine transporter
-
ENGEL K, WANG J: Interaction of organic cations with a newly identified plasma membrane monoamine transporter. Mol. Pharmacol. (2005) 68(5):1397-1407.
-
(2005)
Mol. Pharmacol
, vol.68
, Issue.5
, pp. 1397-1407
-
-
ENGEL, K.1
WANG, J.2
-
142
-
-
9644268195
-
Identification and characterization of a novel monoamine transporter in the human brain
-
ENGEL K, ZHOU M, WANG J: Identification and characterization of a novel monoamine transporter in the human brain. J. Biol. Chem. (2004) 279(48):50042-50049.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.48
, pp. 50042-50049
-
-
ENGEL, K.1
ZHOU, M.2
WANG, J.3
-
143
-
-
0037040390
-
Interaction of human organic anion transporters with various cephalosporin antibiotics
-
TAKEDA M, BABU E, NARIKAWA S, ENDOU H: Interaction of human organic anion transporters with various cephalosporin antibiotics. Eur. J. Pharmacol. (2002) 438(3):137-142.
-
(2002)
Eur. J. Pharmacol
, vol.438
, Issue.3
, pp. 137-142
-
-
TAKEDA, M.1
BABU, E.2
NARIKAWA, S.3
ENDOU, H.4
-
144
-
-
0033815816
-
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1
-
MULATO AS, HO ES, CIHLAR T: Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1. J. Pharmacol. Exp. Ther. (2000) 295(1):10-15.
-
(2000)
J. Pharmacol. Exp. Ther
, vol.295
, Issue.1
, pp. 10-15
-
-
MULATO, A.S.1
HO, E.S.2
CIHLAR, T.3
-
145
-
-
1642422265
-
Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine
-
KHAMDANG S, TAKEDA M, SHIMODA M et al.: Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. J. Pharmacol. Sci. (2004) 94(2):197-202.
-
(2004)
J. Pharmacol. Sci
, vol.94
, Issue.2
, pp. 197-202
-
-
KHAMDANG, S.1
TAKEDA, M.2
SHIMODA, M.3
-
146
-
-
21244505457
-
Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slices
-
SRIMAROENG C, JUTABHA P, PRITCHARD JB, ENDOU H, CHATSUDTHIPONG V: Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slices. Pharm. Res. (2005) 22(6):858-866.
-
(2005)
Pharm. Res
, vol.22
, Issue.6
, pp. 858-866
-
-
SRIMAROENG, C.1
JUTABHA, P.2
PRITCHARD, J.B.3
ENDOU, H.4
CHATSUDTHIPONG, V.5
-
147
-
-
0034757988
-
Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOATL1
-
ISLINGER F, GEKLE M, WRIGHT SH: Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOATL1. Pharmacol. Exp. Ther. (2001) 299(2):741-747.
-
(2001)
Pharmacol. Exp. Ther
, vol.299
, Issue.2
, pp. 741-747
-
-
ISLINGER, F.1
GEKLE, M.2
WRIGHT, S.H.3
-
148
-
-
33645798634
-
Inhibition of OAT3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid
-
TAHARA H, KUSUHARA H, MAEDA K et al.: Inhibition of OAT3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid. Drug Metab. Dispos. (2006) 34(5):743-747.
-
(2006)
Drug Metab. Dispos
, vol.34
, Issue.5
, pp. 743-747
-
-
TAHARA, H.1
KUSUHARA, H.2
MAEDA, K.3
-
149
-
-
0035039326
-
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney
-
CHA SH, SEKINE T, FUKUSHIMA JI et al.: Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol. Pharmacol. (2001) 59(5):1277-1286.
-
(2001)
Mol. Pharmacol
, vol.59
, Issue.5
, pp. 1277-1286
-
-
CHA, S.H.1
SEKINE, T.2
FUKUSHIMA, J.I.3
-
150
-
-
0036198625
-
Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins
-
KIMURA H, TAKEDA M, NARIKAWA S et al.: Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins. J. Pharmacol. Exp. Ther. (2002) 301(1):293-298.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.301
, Issue.1
, pp. 293-298
-
-
KIMURA, H.1
TAKEDA, M.2
NARIKAWA, S.3
-
151
-
-
27744570434
-
Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)
-
BOURDET DL, PRITCHARD JB, THAKKER DR: Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3). J. Pharmacol. Exp. Ther. (2005) 315(3):1288-1297.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.315
, Issue.3
, pp. 1288-1297
-
-
BOURDET, D.L.1
PRITCHARD, J.B.2
THAKKER, D.R.3
-
152
-
-
28244486151
-
Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2
-
CIARIMBOLI G, LUDWIG T, LANG D et al.: Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2. Am. J. Pathol. (2005) 167(6):1477-1484.
-
(2005)
Am. J. Pathol
, vol.167
, Issue.6
, pp. 1477-1484
-
-
CIARIMBOLI, G.1
LUDWIG, T.2
LANG, D.3
-
153
-
-
0030763035
-
Cloning and characterization of two human polyspecific organic cation transporters
-
GORBOULEV V, ULZHEIMER JC, AKHOUNDOVA A et al.: Cloning and characterization of two human polyspecific organic cation transporters. DNA Cell Biol. (1997) 16(7):871-881.
-
(1997)
DNA Cell Biol
, vol.16
, Issue.7
, pp. 871-881
-
-
GORBOULEV, V.1
ULZHEIMER, J.C.2
AKHOUNDOVA, A.3
-
154
-
-
0031824347
-
Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine
-
BUSCH AE, KARBACH U, MISKA D et al.: Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine. Mol. Pharmacol. (1998) 54(2):342-352.
-
(1998)
Mol. Pharmacol
, vol.54
, Issue.2
, pp. 342-352
-
-
BUSCH, A.E.1
KARBACH, U.2
MISKA, D.3
-
155
-
-
0032696186
-
+)-dependent carnitine transport by organic cation transporter (OCTN2): Its pharmacological and toxicological relevance
-
+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. J. Pharmacol. Exp. Ther. (1999) 291(2):778-784.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.291
, Issue.2
, pp. 778-784
-
-
OHASHI, R.1
TAMAI, I.2
YABUUCHI, H.3
-
156
-
-
0034695673
-
β-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter
-
GANAPATHY ME, HUANG W, RAJAN DP et al.: β-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. J. Biol. Chem. (2000) 275(3):1699-1707.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.3
, pp. 1699-1707
-
-
GANAPATHY, M.E.1
HUANG, W.2
RAJAN, D.P.3
-
157
-
-
0344572686
-
CHO/hPEPT1 cells overexpressing the human peptide transporter (hPEPT1) as an alternative in vitro model for peptidomimetic drugs
-
HAN HK, RHIE JK, OH DM et al.: CHO/hPEPT1 cells overexpressing the human peptide transporter (hPEPT1) as an alternative in vitro model for peptidomimetic drugs. J. Pharm. Sci. (1999) 88(3):347-350.
-
(1999)
J. Pharm. Sci
, vol.88
, Issue.3
, pp. 347-350
-
-
HAN, H.K.1
RHIE, J.K.2
OH, D.M.3
-
158
-
-
0032544684
-
Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir
-
BALIMANE PV, TAMAI I, GUO A et al.: Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir. Biochem. Biophys. Res. Commun. (1998) 250(2):246-251.
-
(1998)
Biochem. Biophys. Res. Commun
, vol.250
, Issue.2
, pp. 246-251
-
-
BALIMANE, P.V.1
TAMAI, I.2
GUO, A.3
-
159
-
-
0032546467
-
Valacyclovir: A substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2
-
GANAPATHY ME, HUANG W, WANG H, GANAPATHY V, LEIBACH FH: Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2. Biochem. Biophys. Res. Commun. (1998) 246(2):470-475.
-
(1998)
Biochem. Biophys. Res. Commun
, vol.246
, Issue.2
, pp. 470-475
-
-
GANAPATHY, M.E.1
HUANG, W.2
WANG, H.3
GANAPATHY, V.4
LEIBACH, F.H.5
-
160
-
-
0032916827
-
Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line
-
GUO A, HU P, BALIMANE PV, LEIBACH FH, SINKO PJ: Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line. J. Pharmacol. Exp. Ther. (1999) 289(1):448-454.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.289
, Issue.1
, pp. 448-454
-
-
GUO, A.1
HU, P.2
BALIMANE, P.V.3
LEIBACH, F.H.4
SINKO, P.J.5
-
161
-
-
0040699988
-
+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux
-
+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux. Pharm. Res. (1999) 16(1):55-61.
-
(1999)
Pharm. Res
, vol.16
, Issue.1
, pp. 55-61
-
-
BRETSCHNEIDER, B.1
BRANDSCH, M.2
NEUBERT, R.3
-
162
-
-
9644252691
-
+/peptide symporter PEPT2: Analysis of affinity constants and comparison with PEPT1
-
+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. Eur. J. Pharm. Biopharm. (2005) 59(1):17-24.
-
(2005)
Eur. J. Pharm. Biopharm
, vol.59
, Issue.1
, pp. 17-24
-
-
LUCKNER, P.1
BRANDSCH, M.2
-
164
-
-
0028826927
-
Differential recognition of β-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2
-
GANAPATHY ME, BRANDSCH M, PRASAD PD, GANAPATHY V, LEIBACH FH: Differential recognition of β-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2. J. Biol. Chem. (1995) 270(43):25672-25677.
-
(1995)
J. Biol. Chem
, vol.270
, Issue.43
, pp. 25672-25677
-
-
GANAPATHY, M.E.1
BRANDSCH, M.2
PRASAD, P.D.3
GANAPATHY, V.4
LEIBACH, F.H.5
-
165
-
-
0030892709
-
Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2
-
GANAPATHY ME, PRASAD PD, MACKENZIE B, GANAPATHY V, LEIBACH FH: Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2. Biochim. Biophys. Acta (1997) 1324(2):296-308.
-
(1997)
Biochim. Biophys. Acta
, vol.1324
, Issue.2
, pp. 296-308
-
-
GANAPATHY, M.E.1
PRASAD, P.D.2
MACKENZIE, B.3
GANAPATHY, V.4
LEIBACH, F.H.5
-
166
-
-
0034960419
-
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells
-
GAO J, MURASE O, SCHOWEN RL, AUBE J, BORCHARDT RT: A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells. Pharm. Res. (2001) 18(2):171-176.
-
(2001)
Pharm. Res
, vol.18
, Issue.2
, pp. 171-176
-
-
GAO, J.1
MURASE, O.2
SCHOWEN, R.L.3
AUBE, J.4
BORCHARDT, R.T.5
-
167
-
-
0033862088
-
Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines
-
VAN DER SANDT IC, BLOM-ROOSEMALEN MC, DE BOERAG, BREIMER DD: Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines. Eur. J. Pharm. Sci. (2000) 11(3):207-214.
-
(2000)
Eur. J. Pharm. Sci
, vol.11
, Issue.3
, pp. 207-214
-
-
VAN DER SANDT IC1
Blom-Roosemalen, M.C.2
DE BOERAG3
Breimer, D.D.4
-
168
-
-
0026777528
-
Kinetics of daunorubicin transport by P-glycoprotein of intact cancer cells
-
SPOELSTRA EC, WESTERHOFF HV, DEKKER H, LANKELMA J: Kinetics of daunorubicin transport by P-glycoprotein of intact cancer cells. Eur. J. Biochem. (1992) 207(2):567-579.
-
(1992)
Eur. J. Biochem
, vol.207
, Issue.2
, pp. 567-579
-
-
SPOELSTRA, E.C.1
WESTERHOFF, H.V.2
DEKKER, H.3
LANKELMA, J.4
-
169
-
-
0031719032
-
Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells
-
MAKHEY VD, GUO A, NORRIS DA et al.: Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells. Pharm. Res. (1998) 15(8):1160-1167.
-
(1998)
Pharm. Res
, vol.15
, Issue.8
, pp. 1160-1167
-
-
MAKHEY, V.D.1
GUO, A.2
NORRIS, D.A.3
-
170
-
-
0031941789
-
Taxol transport by human intestinal epithelial Caco-2 cells
-
WALLE UK, WALLE T: Taxol transport by human intestinal epithelial Caco-2 cells. Drug Metab. Dispos. (1998) 26(4):343-346.
-
(1998)
Drug Metab. Dispos
, vol.26
, Issue.4
, pp. 343-346
-
-
WALLE, U.K.1
WALLE, T.2
-
171
-
-
27544483787
-
Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: Influence of cell line and modulator concentration on P-gp activity
-
TAUB ME, PODILA L, ELY D, ALMEIDA I: Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity. Drug Metab. Dispos. (2005) 33(11):1679-1687.
-
(2005)
Drug Metab. Dispos
, vol.33
, Issue.11
, pp. 1679-1687
-
-
TAUB, M.E.1
PODILA, L.2
ELY, D.3
ALMEIDA, I.4
-
172
-
-
2942682950
-
Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery
-
BALIMANE PV, PATEL K, MARINO A, CHONG S: Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery. Eur. J. Pharm. Biopharm. (2004) 58(1):99-105.
-
(2004)
Eur. J. Pharm. Biopharm
, vol.58
, Issue.1
, pp. 99-105
-
-
BALIMANE, P.V.1
PATEL, K.2
MARINO, A.3
CHONG, S.4
-
173
-
-
0027181852
-
Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators
-
HUNTER J, JEPSON MA, TSURUO T, SIMMONS NL, HIRST BH: Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators. J. Biol. Chem. (1993) 268(20):14991-14997.
-
(1993)
J. Biol. Chem
, vol.268
, Issue.20
, pp. 14991-14997
-
-
HUNTER, J.1
JEPSON, M.A.2
TSURUO, T.3
SIMMONS, N.L.4
HIRST, B.H.5
-
174
-
-
0032804327
-
Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor
-
POLLI JW, JARRETT JL, STUDENBERG SD et al: Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor. Pharm. Res. (1999) 16(8):1206-1212.
-
(1999)
Pharm. Res
, vol.16
, Issue.8
, pp. 1206-1212
-
-
POLLI, J.W.1
JARRETT, J.L.2
STUDENBERG, S.D.3
-
175
-
-
18344364851
-
Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates
-
EKINS S, KIM RB, LEAKE BF et al: Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates. Mol. Pharmacol. (2002) 61(5):974-981.
-
(2002)
Mol. Pharmacol
, vol.61
, Issue.5
, pp. 974-981
-
-
EKINS, S.1
KIM, R.B.2
LEAKE, B.F.3
-
176
-
-
27144514512
-
MDR1 G1199A polymorphism alters permeability of HIV protease inhibitors across P-glycoprotein-expressing epithelial cells
-
WOODAHL EL, YANG Z, BUI T, SHEN DD, HO RJ: MDR1 G1199A polymorphism alters permeability of HIV protease inhibitors across P-glycoprotein-expressing epithelial cells. AIDS (2005) 19(15):1617-1625.
-
(2005)
AIDS
, vol.19
, Issue.15
, pp. 1617-1625
-
-
WOODAHL, E.L.1
YANG, Z.2
BUI, T.3
SHEN, D.D.4
HO, R.J.5
-
177
-
-
18344390872
-
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein
-
EKINS S, KIM RB, LEAKE BF et al.: Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. Mol. Pharmacol. (2002) 61(5):964-973.
-
(2002)
Mol. Pharmacol
, vol.61
, Issue.5
, pp. 964-973
-
-
EKINS, S.1
KIM, R.B.2
LEAKE, B.F.3
-
178
-
-
0036135397
-
Interaction of common azole antifungals with P glycoprotein
-
WANG EJ, LEW K, CASCIANO CN, CLEMENT RP, JOHNSON WW: Interaction of common azole antifungals with P glycoprotein. Antimicrob. Agents Chemother. (2002) 46(1):160-165.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, Issue.1
, pp. 160-165
-
-
WANG, E.J.1
LEW, K.2
CASCIANO, C.N.3
CLEMENT, R.P.4
JOHNSON, W.W.5
-
179
-
-
0029986277
-
Relevance of P-glycoprotein for the enteral absorption of cyclosporin A: In vitro-in vivo correlation
-
FRICKER G, DREWE J, HUWYLER J, GUTMANN H, BEGLINGER C: Relevance of P-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation. Br. J. Pharmacol. (1996) 118(7):1841-1847.
-
(1996)
Br. J. Pharmacol
, vol.118
, Issue.7
, pp. 1841-1847
-
-
FRICKER, G.1
DREWE, J.2
HUWYLER, J.3
GUTMANN, H.4
BEGLINGER, C.5
-
180
-
-
0027418815
-
Human P-glycoprotein transports cyclosporin A and FK-506
-
SAEKI T, UEDA K, TANIGAWARA Y, HORI R, KOMANO T: Human P-glycoprotein transports cyclosporin A and FK-506. J. Biol. Chem. (1993) 268(9):6077-6080.
-
(1993)
J. Biol. Chem
, vol.268
, Issue.9
, pp. 6077-6080
-
-
SAEKI, T.1
UEDA, K.2
TANIGAWARA, Y.3
HORI, R.4
KOMANO, T.5
-
181
-
-
0032807119
-
P-glycoprotein-dependent disposition kinetics of tacrolimus: Studies in mdr1a knockout mice
-
YOKOGAWA K, TAKAHASHI M, TAMAI I et al.: P-glycoprotein-dependent disposition kinetics of tacrolimus: studies in mdr1a knockout mice. Pharm. Res. (1999) 16(8):1213-1218.
-
(1999)
Pharm. Res
, vol.16
, Issue.8
, pp. 1213-1218
-
-
YOKOGAWA, K.1
TAKAHASHI, M.2
TAMAI, I.3
-
182
-
-
11344284146
-
P-glycoprotein and surfactants: Effect on intestinal talinolol absorption
-
BOGMAN K, ZYSSET Y, DEGEN L et al.: P-glycoprotein and surfactants: effect on intestinal talinolol absorption. Clin. Pharmacol. Ther. (2005) 77(1):24-32.
-
(2005)
Clin. Pharmacol. Ther
, vol.77
, Issue.1
, pp. 24-32
-
-
BOGMAN, K.1
ZYSSET, Y.2
DEGEN, L.3
-
183
-
-
0032589932
-
Modulation of the permeability of H2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2
-
COLLETT A, HIGGS NB, SIMS E, ROWLAND M, WARHURST G: Modulation of the permeability of H2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2. J. Pharmacol. Exp. Ther. (1999) 288(1):171-178.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.288
, Issue.1
, pp. 171-178
-
-
COLLETT, A.1
HIGGS, N.B.2
SIMS, E.3
ROWLAND, M.4
WARHURST, G.5
-
184
-
-
4344594700
-
Transport characteristics of fexofenadine in the Caco-2 cell model
-
PETRI N, TANNERGREN C, RUNGSTAD D, LENNERNAS H: Transport characteristics of fexofenadine in the Caco-2 cell model. Pharm. Res. (2004) 21(8):1398-1404.
-
(2004)
Pharm. Res
, vol.21
, Issue.8
, pp. 1398-1404
-
-
PETRI, N.1
TANNERGREN, C.2
RUNGSTAD, D.3
LENNERNAS, H.4
-
185
-
-
0035146553
-
Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia
-
STEPHENS RH, O'NEILL CA, WARHURST A et al.: Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia. J. Pharmacol. Exp. Ther. (2001) 296(2):584-591.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.296
, Issue.2
, pp. 584-591
-
-
STEPHENS, R.H.1
O'NEILL, C.A.2
WARHURST, A.3
-
186
-
-
0026707951
-
P-glycoprotein transports corticosterone and is photoaffinity-Iabeled by the steroid
-
WOLF DC, HORWITZ SB: P-glycoprotein transports corticosterone and is photoaffinity-Iabeled by the steroid. Int. J. Cancer (1992) 52(1):141-146.
-
(1992)
Int. J. Cancer
, vol.52
, Issue.1
, pp. 141-146
-
-
WOLF, D.C.1
HORWITZ, S.B.2
-
187
-
-
0036839699
-
Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2)
-
WILLIAMS GC, LIU A, KNIPP G, SINKO PJ: Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2). Antimicrob. Agents Chemother. (2002) 46(11):3456-3462.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, Issue.11
, pp. 3456-3462
-
-
WILLIAMS, G.C.1
LIU, A.2
KNIPP, G.3
SINKO, P.J.4
-
188
-
-
0034072174
-
Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions
-
BAKOS E, EVERS R, SINKO E et al.: Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions. Mol. Pharmacol. (2000) 57(4):760-768.
-
(2000)
Mol. Pharmacol
, vol.57
, Issue.4
, pp. 760-768
-
-
BAKOS, E.1
EVERS, R.2
SINKO, E.3
-
189
-
-
0031788927
-
Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters
-
SRINIVAS RV, MIDDLEMAS D, FLYNN P, FRIDLAND A: Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters. Antimicrob. Agents Chemother. (1998) 42(12):3157-3162.
-
(1998)
Antimicrob. Agents Chemother
, vol.42
, Issue.12
, pp. 3157-3162
-
-
SRINIVAS, R.V.1
MIDDLEMAS, D.2
FLYNN, P.3
FRIDLAND, A.4
-
190
-
-
0033021424
-
ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1
-
RENES J, DE VRIES EG, NIENHUIS EF, JANSEN PL, MULLER M: ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1. Br. J. Pharmacol. (1999) 126(3):681-688.
-
(1999)
Br. J. Pharmacol
, vol.126
, Issue.3
, pp. 681-688
-
-
RENES, J.1
DE VRIES EG2
Nienhuis, E.F.3
Jansen, P.L.4
Muller, M.5
-
191
-
-
11144264060
-
Potentiation by α-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells
-
KANG YH, LEE E, YOUK HJ et al.: Potentiation by α-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells. Cancer Lett. (2005) 217(2):181-190.
-
(2005)
Cancer Lett
, vol.217
, Issue.2
, pp. 181-190
-
-
KANG, Y.H.1
LEE, E.2
YOUK, H.J.3
-
192
-
-
0027984511
-
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates
-
LEIER I, JEDLITSCHKY G, BUCHHOLZ U et al: The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. J. Biol. Chem. (1994) 269(45):27807-27810.
-
(1994)
J. Biol. Chem
, vol.269
, Issue.45
, pp. 27807-27810
-
-
LEIER, I.1
JEDLITSCHKY, G.2
BUCHHOLZ, U.3
-
193
-
-
0030063480
-
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
-
JEDLITSCHKY G, LEIER I, BUCHHOLZ U et al.: Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res. (1996) 56(5):988-994.
-
(1996)
Cancer Res
, vol.56
, Issue.5
, pp. 988-994
-
-
JEDLITSCHKY, G.1
LEIER, I.2
BUCHHOLZ, U.3
-
194
-
-
0034083906
-
ATP-dependent para-aminohippurare transport by apical multidrug resistance protein MRP2
-
LEIER I, HUMMEL-EISENBEISS J, CUI Y, KEPPLER D: ATP-dependent para-aminohippurare transport by apical multidrug resistance protein MRP2. Kidney Int. (2000) 57(4):1636-1642.
-
(2000)
Kidney Int
, vol.57
, Issue.4
, pp. 1636-1642
-
-
LEIER, I.1
HUMMEL-EISENBEISS, J.2
CUI, Y.3
KEPPLER, D.4
-
195
-
-
0345299165
-
Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells
-
CUI Y, KONIG J, BUCHHOLZ JK et al.: Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells. Mol. Pharmacol. (1999) 55(5):929-937.
-
(1999)
Mol. Pharmacol
, vol.55
, Issue.5
, pp. 929-937
-
-
CUI, Y.1
KONIG, J.2
BUCHHOLZ, J.K.3
-
196
-
-
0036206470
-
Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT)
-
GUO A, MARINARO W, HU P, SINKO PJ: Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT). Drug Metab. Dispos. (2002) 30(4):457-463.
-
(2002)
Drug Metab. Dispos
, vol.30
, Issue.4
, pp. 457-463
-
-
GUO, A.1
MARINARO, W.2
HU, P.3
SINKO, P.J.4
-
197
-
-
0036166635
-
Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2)
-
FLANAGAN SD, CUMMINS CL, SUSANTO M et al.: Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2). Pharmacology (2002) 64(3):126-134.
-
(2002)
Pharmacology
, vol.64
, Issue.3
, pp. 126-134
-
-
FLANAGAN, S.D.1
CUMMINS, C.L.2
SUSANTO, M.3
-
198
-
-
0032781499
-
Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2)
-
KAWABE T, CHEN ZS, WADA M et al.: Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2). FEBS Lett. (1999) 456(2):327-331.
-
(1999)
FEBS Lett
, vol.456
, Issue.2
, pp. 327-331
-
-
KAWABE, T.1
CHEN, Z.S.2
WADA, M.3
-
199
-
-
0037613131
-
The potential for an interaction be ween MRP2 (ABCC2) and various therapeutic agents: Probenecid as a candidate inhibitor of the biliary excretion of irinotecan metabolites
-
HORIKAWA M, KATO Y, TYSON CA, SUGIYAMA Y: The potential for an interaction be ween MRP2 (ABCC2) and various therapeutic agents: probenecid as a candidate inhibitor of the biliary excretion of irinotecan metabolites. Drug Metab. Pharmacokinet. (2002) 17(1):23-33.
-
(2002)
Drug Metab. Pharmacokinet
, vol.17
, Issue.1
, pp. 23-33
-
-
HORIKAWA, M.1
KATO, Y.2
TYSON, C.A.3
SUGIYAMA, Y.4
-
200
-
-
0034282991
-
Transport of amphipathic anions by human multidrug resistance protein 3
-
ZENG H, LIU G, REA PA, KRUH GD: Transport of amphipathic anions by human multidrug resistance protein 3. Cancer Res. (2000) 60(17):4779-4784.
-
(2000)
Cancer Res
, vol.60
, Issue.17
, pp. 4779-4784
-
-
ZENG, H.1
LIU, G.2
REA, P.A.3
KRUH, G.D.4
-
201
-
-
0035824674
-
Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3)
-
ZELCER N, SAEKIT, REID G, BEIJNEN JH, BURST P: Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). J. Biol. Chem. (2001) 276(49):46400-46407.
-
(2001)
J. Biol. Chem
, vol.276
, Issue.49
, pp. 46400-46407
-
-
ZELCER, N.1
SAEKIT, R.G.2
BEIJNEN, J.H.3
BURST, P.4
-
202
-
-
0035823559
-
Transport of cyclic nucleotides and estradiol 17-β-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
-
CHEN ZS, LEE K, KRUH GD: Transport of cyclic nucleotides and estradiol 17-β-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. J. Biol. Chem. (2001) 276(36):33747-33754.
-
(2001)
J. Biol. Chem
, vol.276
, Issue.36
, pp. 33747-33754
-
-
CHEN, Z.S.1
LEE, K.2
KRUH, G.D.3
-
203
-
-
0036471128
-
Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues
-
LAI L, TAN TM: Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues. Biochem. J. (2002) 361(Pt 3):497-503.
-
(2002)
Biochem. J
, vol.361
, Issue.PART 3
, pp. 497-503
-
-
LAI, L.1
TAN, T.M.2
-
204
-
-
0036606023
-
Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system
-
CHEN ZS, LEE K, WALTHER S et al.: Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system. Cancer Res. (2002) 62(11):3144-3150.
-
(2002)
Cancer Res
, vol.62
, Issue.11
, pp. 3144-3150
-
-
CHEN, Z.S.1
LEE, K.2
WALTHER, S.3
-
205
-
-
0043132421
-
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs
-
REID G, WIELINGA P, ZELCER N et al.: The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc. Natl. Acad. Sci. USA (2003) 100(16):9244-9249.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.16
, pp. 9244-9249
-
-
REID, G.1
WIELINGA, P.2
ZELCER, N.3
-
207
-
-
0016205272
-
Pharmacokinetics of parenteral sodium cephalexin in comparison with cephalothin and cefazolin
-
REGAMEY C, LIBKE RD, CLARKE JT, KIRBY WM: Pharmacokinetics of parenteral sodium cephalexin in comparison with cephalothin and cefazolin. Infection (1974) 2(3):132-136.
-
(1974)
Infection
, vol.2
, Issue.3
, pp. 132-136
-
-
REGAMEY, C.1
LIBKE, R.D.2
CLARKE, J.T.3
KIRBY, W.M.4
-
208
-
-
0017645455
-
Effect of probenecid on the blood levels and urinary excretion of cefamandole
-
GRIFFITH RS, BLACK HR, BRIER GL, WOLNY JD: Effect of probenecid on the blood levels and urinary excretion of cefamandole. Antimicrob. Agents Chemother. (1977) 11(5):809-812.
-
(1977)
Antimicrob. Agents Chemother
, vol.11
, Issue.5
, pp. 809-812
-
-
GRIFFITH, R.S.1
BLACK, H.R.2
BRIER, G.L.3
WOLNY, J.D.4
-
209
-
-
0024511555
-
The effect of probenecid on the renal elimination of cimetidine
-
GISCLON LG, BOYD RA, WILLIAMS RL, GIACOMINI KM: The effect of probenecid on the renal elimination of cimetidine. Clin. Pharmacol. Ther. (1989) 45(4):444-452.
-
(1989)
Clin. Pharmacol. Ther
, vol.45
, Issue.4
, pp. 444-452
-
-
GISCLON, L.G.1
BOYD, R.A.2
WILLIAMS, R.L.3
GIACOMINI, K.M.4
-
210
-
-
0019497381
-
Pharmacokinetics of cephradine given intravenously with and without probenecid
-
ROBERTS DH, KENDALL MJ, JACK DB, WELLING PG: Pharmacokinetics of cephradine given intravenously with and without probenecid. Br. J. Clin. Pharmacol. (1981) 11(6):561-564.
-
(1981)
Br. J. Clin. Pharmacol
, vol.11
, Issue.6
, pp. 561-564
-
-
ROBERTS, D.H.1
KENDALL, M.J.2
JACK, D.B.3
WELLING, P.G.4
-
211
-
-
0028285829
-
The renal clearance of cefuroxime and ceftazidime and the effect of probenecid on their tubular excretion
-
VERHAGEN CA, MATTIE H, VAN STRIJEN E: The renal clearance of cefuroxime and ceftazidime and the effect of probenecid on their tubular excretion. Br. J. Clin. Pharmacol. (1994) 37(2):193-197.
-
(1994)
Br. J. Clin. Pharmacol
, vol.37
, Issue.2
, pp. 193-197
-
-
VERHAGEN, C.A.1
MATTIE, H.2
VAN STRIJEN, E.3
-
212
-
-
0021154184
-
Inhibition of cis-diamminedichloroplarinum secretion by the human kidney with probenecid
-
JACOBS C, COLEMAN CN, RICH L, HIRST K, WEINER MW: Inhibition of cis-diamminedichloroplarinum secretion by the human kidney with probenecid. Cancer Res. (1984) 44(8):3632-3635.
-
(1984)
Cancer Res
, vol.44
, Issue.8
, pp. 3632-3635
-
-
JACOBS, C.1
COLEMAN, C.N.2
RICH, L.3
HIRST, K.4
WEINER, M.W.5
-
213
-
-
0025055624
-
The inhibitory effect of probenecid on renal excretion of famotidine in young, healthy volunteers
-
INOTSUME N, NISHIMURA M, NAKANO M, FUJIYAMA S, SATO T: The inhibitory effect of probenecid on renal excretion of famotidine in young, healthy volunteers. J. Clin. Pharmacol. (1990) 30(1):50-56.
-
(1990)
J. Clin. Pharmacol
, vol.30
, Issue.1
, pp. 50-56
-
-
INOTSUME, N.1
NISHIMURA, M.2
NAKANO, M.3
FUJIYAMA, S.4
SATO, T.5
-
214
-
-
11344279702
-
Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics
-
YASUI-FURUKORI N, UNO T, SUGAWARA K, TATEISHI T: Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics. Clin. Pharmacol. Ther. (2005) 77(1):17-23.
-
(2005)
Clin. Pharmacol. Ther
, vol.77
, Issue.1
, pp. 17-23
-
-
YASUI-FURUKORI, N.1
UNO, T.2
SUGAWARA, K.3
TATEISHI, T.4
-
215
-
-
0029923717
-
The effect of probenecid on the pharmacokinetics of zalcitabine in HIV-positive patients
-
MASSARELLA JW, NAZARENO LA, PASSE S, MIN B: The effect of probenecid on the pharmacokinetics of zalcitabine in HIV-positive patients. Pharm. Res. (1996) 13(3):449-452.
-
(1996)
Pharm. Res
, vol.13
, Issue.3
, pp. 449-452
-
-
MASSARELLA, J.W.1
NAZARENO, L.A.2
PASSE, S.3
MIN, B.4
-
216
-
-
0032030860
-
Pharmacokinetics of oral ganciclovir alone and in combination with zidovudine, didanosine, and probenecid in HIV-infected subjects
-
CIMOCH PJ, LAVELLE J, POLLARD R et al.: Pharmacokinetics of oral ganciclovir alone and in combination with zidovudine, didanosine, and probenecid in HIV-infected subjects. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. (1998) 17(3):227-234.
-
(1998)
J. Acquir. Immune Defic. Syndr. Hum. Retrovirol
, vol.17
, Issue.3
, pp. 227-234
-
-
CIMOCH, P.J.1
LAVELLE, J.2
POLLARD, R.3
-
217
-
-
0028822282
-
Effect of probenecid on the distribution and elimination of ciprofloxacin in humans
-
JAEHDE U, SORGEL F, REITER A et al.: Effect of probenecid on the distribution and elimination of ciprofloxacin in humans. Clin. Pharmacol. Ther. (1995) 58(5):532-541.
-
(1995)
Clin. Pharmacol. Ther
, vol.58
, Issue.5
, pp. 532-541
-
-
JAEHDE, U.1
SORGEL, F.2
REITER, A.3
-
219
-
-
0031919208
-
Stereoselective disposition of sulbenicillin in humans
-
ITOH T, WATANABE N, ISHIDA M et al.: Stereoselective disposition of sulbenicillin in humans. Antimicrob. Agents Chemother. (1998) 42(2):325-331.
-
(1998)
Antimicrob. Agents Chemother
, vol.42
, Issue.2
, pp. 325-331
-
-
ITOH, T.1
WATANABE, N.2
ISHIDA, M.3
-
220
-
-
0023730329
-
Lack of effect of cimetidine on the metabolism of quinidine: Effect on renal clearance
-
HARDY BG, SCHENTAG JJ: Lack of effect of cimetidine on the metabolism of quinidine: effect on renal clearance. Int. J. Clin. Pharmacol. Ther. Toxicol. (1988) 26(8):388-391.
-
(1988)
Int. J. Clin. Pharmacol. Ther. Toxicol
, vol.26
, Issue.8
, pp. 388-391
-
-
HARDY, B.G.1
SCHENTAG, J.J.2
-
221
-
-
0022631053
-
Selectivity of the cimetidine-induced alterations in the renal handling of organic substrates in humans. Studies with anionic, cationic and zwitterionic drugs
-
VAN CRUGTEN J, BOCHNER F, KEAL J, SOMOGYI A: Selectivity of the cimetidine-induced alterations in the renal handling of organic substrates in humans. Studies with anionic, cationic and zwitterionic drugs. J Pharmacol. Exp. Ther. (1986) 236(2):481-487.
-
(1986)
J Pharmacol. Exp. Ther
, vol.236
, Issue.2
, pp. 481-487
-
-
VAN CRUGTEN, J.1
BOCHNER, F.2
KEAL, J.3
SOMOGYI, A.4
-
222
-
-
0034025366
-
Effect of cimetidine and probenecid on pilsicainide renal clearance in humans
-
SHIGA T, HASHIGUCHI M, URAE A, KASANUKI H, RIKIHISA T: Effect of cimetidine and probenecid on pilsicainide renal clearance in humans. Clin. Pharmacol. Ther. (2000) 67(3):222-228.
-
(2000)
Clin. Pharmacol. Ther
, vol.67
, Issue.3
, pp. 222-228
-
-
SHIGA, T.1
HASHIGUCHI, M.2
URAE, A.3
KASANUKI, H.4
RIKIHISA, T.5
-
223
-
-
0028869116
-
The effect of cimetidine and ranitidine administration with zidovudine
-
FLETCHER CV, HENRY WK, NOORMOHAMED SE, RHAME FS, BALFOUR HH Jr: The effect of cimetidine and ranitidine administration with zidovudine. Pharmacotherapy (1995) 15(6):701-708.
-
(1995)
Pharmacotherapy
, vol.15
, Issue.6
, pp. 701-708
-
-
FLETCHER, C.V.1
HENRY, W.K.2
NOORMOHAMED, S.E.3
RHAME, F.S.4
BALFOUR Jr, H.H.5
-
224
-
-
0023855201
-
Pharmacokinetic drug interactions between triamterene and ranitidine in humans: Alterations in renal and hepatic clearances and gastrointestinal absorption
-
MUIRHEAD M, BOCHNER F, SOMOGYI A: Pharmacokinetic drug interactions between triamterene and ranitidine in humans: alterations in renal and hepatic clearances and gastrointestinal absorption. J. Pharmacol. Exp. Ther. (1988) 244(2):734-739.
-
(1988)
J. Pharmacol. Exp. Ther
, vol.244
, Issue.2
, pp. 734-739
-
-
MUIRHEAD, M.1
BOCHNER, F.2
SOMOGYI, A.3
-
225
-
-
0021133374
-
Dose and concentration dependent effect of ranitidine on procainamide disposition and renal clearance in man
-
SOMOGYI A, BOCHNER F: Dose and concentration dependent effect of ranitidine on procainamide disposition and renal clearance in man. Br. J. Clin. Pharmacol. (1984) 18(2):175-181.
-
(1984)
Br. J. Clin. Pharmacol
, vol.18
, Issue.2
, pp. 175-181
-
-
SOMOGYI, A.1
BOCHNER, F.2
-
226
-
-
16244408295
-
Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances
-
BAUER LA, BLACK DJ, LILL JS et al.: Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances. Antimicrob. Agents Chemother. (2005) 49(4):1649-1651.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, Issue.4
, pp. 1649-1651
-
-
BAUER, L.A.1
BLACK, D.J.2
LILL, J.S.3
-
227
-
-
0026475448
-
Trimethoprim, alone or in combination with sulphamethoxazole, decreases the renal excretion of zidovudine and its glucuronide
-
CHATTON JY, MUNAFO A, CHAVE JP et al.: Trimethoprim, alone or in combination with sulphamethoxazole, decreases the renal excretion of zidovudine and its glucuronide. Br. J. Clin. Pharmacol. (1992) 34(6):551-554.
-
(1992)
Br. J. Clin. Pharmacol
, vol.34
, Issue.6
, pp. 551-554
-
-
CHATTON, J.Y.1
MUNAFO, A.2
CHAVE, J.P.3
-
228
-
-
0032698091
-
Longitudinal assessment of a P-glycoprotein-mediated drug interaction of valspodar on digoxin
-
KOVARIK JM, RIGAUDY L, GUERRET M, GERBEAU C, ROST KL: Longitudinal assessment of a P-glycoprotein-mediated drug interaction of valspodar on digoxin. Clin. Pharmacol. Ther. (1999) 66(4):391-400.
-
(1999)
Clin. Pharmacol. Ther
, vol.66
, Issue.4
, pp. 391-400
-
-
KOVARIK, J.M.1
RIGAUDY, L.2
GUERRET, M.3
GERBEAU, C.4
ROST, K.L.5
-
229
-
-
0023922967
-
Digoxin-cyclosporine interaction: Severe digitalis toxicity after cyclosporine treatment
-
DORIAN P, STRAUSS M, CARDELLA C et al.: Digoxin-cyclosporine interaction: severe digitalis toxicity after cyclosporine treatment. Clin. Invest. Med. (1988) 11(2):108-112.
-
(1988)
Clin. Invest. Med
, vol.11
, Issue.2
, pp. 108-112
-
-
DORIAN, P.1
STRAUSS, M.2
CARDELLA, C.3
-
230
-
-
0020614706
-
Interaction between digoxin and calcium antagonists and antiarrhythmic drugs
-
BELZ GG, DOERING W, MUNKES R, MATTHEWS J: Interaction between digoxin and calcium antagonists and antiarrhythmic drugs. Clin. Pharmacol. Ther. (1983) 33(4):410-417.
-
(1983)
Clin. Pharmacol. Ther
, vol.33
, Issue.4
, pp. 410-417
-
-
BELZ, G.G.1
DOERING, W.2
MUNKES, R.3
MATTHEWS, J.4
-
231
-
-
0021801642
-
Digoxin-trimethoprim interaction
-
PETERSEN P, KASTRUP J, BARTRAM R, MOLHOLM HANSEN J: Digoxin-trimethoprim interaction. Acta Med. Scand. (1985) 217(4):423-427.
-
(1985)
Acta Med. Scand
, vol.217
, Issue.4
, pp. 423-427
-
-
PETERSEN, P.1
KASTRUP, J.2
BARTRAM, R.3
MOLHOLM, H.J.4
|