Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2)

Pharmaceutical Research

Volumn 19, Issue 8, 2002, Pages 1244-1247

  Dresser, Mark J ^a   Xiao, Guangqing ^a   Leabman, Maya K ^a   Gray, Andrew T ^a   Giacomini, Kathleen M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Metformin; Organic cation; Phenformin; Selectivity; Transporter

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; AMMONIUM DERIVATIVE; BIGUANIDE DERIVATIVE; CARRIER PROTEIN; CATION; CIMETIDINE; METFORMIN; N TETRABUTYLAMMONIUM; N TETRAETHYLAMMONIUM; N TETRAMETHYLAMMONIUM; N TETRAPROPYLAMMONIUM; PHENFORMIN; QUINIDINE; TRITIUM; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ELIMINATION; DRUG PROTEIN BINDING; DRUG SPECIFICITY; DRUG TRANSPORT; DRUG UPTAKE; ELECTROPHYSIOLOGY; INCUBATION TIME; INHIBITION KINETICS; KIDNEY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCINTILLATION COUNTING; XENOPUS LAEVIS;

ANIMALS; BIGUANIDES; FEMALE; HUMANS; ORGANIC CATION TRANSPORT PROTEINS; QUATERNARY AMMONIUM COMPOUNDS; XENOPUS LAEVIS;

EID: 0036689433     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019870831174     Document Type: Article

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