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Volumn 26, Issue 4, 1998, Pages 343-346

Taxol transport by human intestinal epithelial Caco-2 cells

Author keywords

[No Author keywords available]

Indexed keywords

PACLITAXEL;

EID: 0031941789     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (95)

References (28)
  • 1
    • 0025311288 scopus 로고
    • Epithelial transport of drugs in cell culture. I. A model for studying the passive diffusion of drugs over intestinal absorbtive (Caco-2) cells
    • Artursson P (1990) Epithelial transport of drugs in cell culture. I. A model for studying the passive diffusion of drugs over intestinal absorbtive (Caco-2) cells. J Pharm Sci 79:476-482.
    • (1990) J Pharm Sci , vol.79 , pp. 476-482
    • Artursson, P.1
  • 2
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
    • Artursson P and Karlsson J (1991) Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem Biophys Res Commun 175:880-885.
    • (1991) Biochem Biophys Res Commun , vol.175 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 4
    • 0029997940 scopus 로고    scopus 로고
    • Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells
    • Cavet ME, West M and Simmons NL (1996) Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells. Br J Pharmacol 118:1389-1396.
    • (1996) Br J Pharmacol , vol.118 , pp. 1389-1396
    • Cavet, M.E.1    West, M.2    Simmons, N.L.3
  • 5
    • 0029120525 scopus 로고
    • Sparfloxacin secretion across Caco-2 cells involves a multidrug resistance-like mechanism
    • Cormet E, Barlier AM, Huneau JF, Rubinstein E, Carbon C, Farinotti R and Tomé D (1995) Sparfloxacin secretion across Caco-2 cells involves a multidrug resistance-like mechanism. Drugs 49(Suppl 2):307-309.
    • (1995) Drugs , vol.49 , Issue.2 SUPPL. , pp. 307-309
    • Cormet, E.1    Barlier, A.M.2    Huneau, J.F.3    Rubinstein, E.4    Carbon, C.5    Farinotti, R.6    Tomé, D.7
  • 6
    • 0027954464 scopus 로고
    • Taxol metabolism by human liver microsomes: Identification of cytochrome P450 isozymes involved in its biotransformation
    • Cresteil T, Monsarrat B, Alvinerie P, Treluyer JM, Vieira I and Wright M (1994) Taxol metabolism by human liver microsomes: Identification of cytochrome P450 isozymes involved in its biotransformation. Cancer Res 54:386-392.
    • (1994) Cancer Res , vol.54 , pp. 386-392
    • Cresteil, T.1    Monsarrat, B.2    Alvinerie, P.3    Treluyer, J.M.4    Vieira, I.5    Wright, M.6
  • 8
    • 0029986277 scopus 로고    scopus 로고
    • Relevance of P-glycoprotein for the enteral absorption of cyclosporin A: In vitro-in vivo correlation
    • Fricker G, Drewe J, Huwyler J, Gutmann H and Beglinger C (1996) Relevance of P-glycoprotein for the enteral absorption of cyclosporin A: In vitro-in vivo correlation. Br J Pharmacol 118:1841-1847.
    • (1996) Br J Pharmacol , vol.118 , pp. 1841-1847
    • Fricker, G.1    Drewe, J.2    Huwyler, J.3    Gutmann, H.4    Beglinger, C.5
  • 9
    • 9044252313 scopus 로고    scopus 로고
    • CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells: Interaction between the two biochemical barriers to intestinal transport
    • Gan L-SL, Moseley MA, Khosla B, Augustijns PF, Bradshaw TP, Hendren RW and Thakker DR (1996) CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells: Interaction between the two biochemical barriers to intestinal transport. Drug Metab Dispos 24:344-349.
    • (1996) Drug Metab Dispos , vol.24 , pp. 344-349
    • Gan, L.-S.L.1    Moseley, M.A.2    Khosla, B.3    Augustijns, P.F.4    Bradshaw, T.P.5    Hendren, R.W.6    Thakker, D.R.7
  • 10
    • 0028590127 scopus 로고
    • Biochemistry and molecular biology of the human CYP2C subfamily
    • Goldstein JA and de Morais SMF (1994) Biochemistry and molecular biology of the human CYP2C subfamily. Pharmacogenetics 4:285-299.
    • (1994) Pharmacogenetics , vol.4 , pp. 285-299
    • Goldstein, J.A.1    De Morais, S.M.F.2
  • 11
    • 0021868158 scopus 로고
    • Cross-resistance of vinblastine- and taxol-resistant mutants of Chinese hamster ovary cells to other anticancer drugs
    • Gupta RS (1985) Cross-resistance of vinblastine-and taxol-resistant mutants of Chinese hamster ovary cells to other anticancer drugs. Cancer Treat Rep 69:515-521.
    • (1985) Cancer Treat Rep , vol.69 , pp. 515-521
    • Gupta, R.S.1
  • 12
    • 0027957132 scopus 로고
    • Metabolism of taxol by human hepatic microsomes and liver slices: Participation of cytochrome P450 3A4 and an unknown P450 enzyme
    • Harris JW, Rahman A, Kim B-R, Guengerich FP and Collins JM (1994) Metabolism of taxol by human hepatic microsomes and liver slices: Participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Res 54:4026-4035.
    • (1994) Cancer Res , vol.54 , pp. 4026-4035
    • Harris, J.W.1    Rahman, A.2    Kim, B.-R.3    Guengerich, F.P.4    Collins, J.M.5
  • 14
    • 0029896241 scopus 로고    scopus 로고
    • Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers
    • Hosoya KI, Kim KJ and Lee VH (1996) Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers. Pharm Res 13:885-890
    • (1996) Pharm Res , vol.13 , pp. 885-890
    • Hosoya, K.I.1    Kim, K.J.2    Lee, V.H.3
  • 15
    • 0027180795 scopus 로고
    • Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers
    • Hunter J, Hirst BH and Simmons NL (1993a) Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers. Pharm Res 10:743-749.
    • (1993) Pharm Res , vol.10 , pp. 743-749
    • Hunter, J.1    Hirst, B.H.2    Simmons, N.L.3
  • 16
    • 0027181852 scopus 로고
    • Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells: Kinetics of vinblastine secretion and interaction with modulators
    • Hunter J, Jepson MA, Tsuruo T, Simmons NL and Hirst BH (1993b) Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells: Kinetics of vinblastine secretion and interaction with modulators. J Biol Chem 268:14991-14997.
    • (1993) J Biol Chem , vol.268 , pp. 14991-14997
    • Hunter, J.1    Jepson, M.A.2    Tsuruo, T.3    Simmons, N.L.4    Hirst, B.H.5
  • 17
    • 0026464616 scopus 로고
    • Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
    • Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C and Watkins PB (1992) Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 90:1871-1878.
    • (1992) J Clin Invest , vol.90 , pp. 1871-1878
    • Kolars, J.C.1    Schmiedlin-Ren, P.2    Schuetz, J.D.3    Fang, C.4    Watkins, P.B.5
  • 18
    • 0028786481 scopus 로고
    • The human intestinal epithelial cell line Caco-2: Pharmacological and pharmacokinetic applications
    • Meunier V, Bourrié M, Berger Y and Fabre G (1995) The human intestinal epithelial cell line Caco-2: Pharmacological and pharmacokinetic applications. Cell Biol Toxicol 11:187-194.
    • (1995) Cell Biol Toxicol , vol.11 , pp. 187-194
    • Meunier, V.1    Bourrié, M.2    Berger, Y.3    Fabre, G.4
  • 19
    • 0022560656 scopus 로고
    • 2+ channel blockers to enhance inhibition by taxol of growth of drug-sensitive and -resistant Chinese hamster ovary cells
    • 2+ channel blockers to enhance inhibition by taxol of growth of drug-sensitive and -resistant Chinese hamster ovary cells. Cancer Treat Rep 70:275-278.
    • (1986) Cancer Treat Rep , vol.70 , pp. 275-278
    • Racker, E.1    Wu, L.-T.2    Westcott, D.3
  • 20
    • 0028036727 scopus 로고
    • Selective biotransformation of taxol to 6α-hydroxytaxol by human cytochrome P450 2C8
    • Rahman A, Korzekwa KR, Grogan J, Gonzalez FJ and Harris JW (1994) Selective biotransformation of taxol to 6α-hydroxytaxol by human cytochrome P450 2C8. Cancer Res 54:5543-5546.
    • (1994) Cancer Res , vol.54 , pp. 5543-5546
    • Rahman, A.1    Korzekwa, K.R.2    Grogan, J.3    Gonzalez, F.J.4    Harris, J.W.5
  • 22
    • 0026723301 scopus 로고
    • Taxol: The first of the taxanes, an important new class of antitumor agents
    • Rowinsky EK, Onetto N, Canetta RM and Arbuck SG (1992) Taxol: The first of the taxanes, an important new class of antitumor agents. Semin Oncol 19:646-662.
    • (1992) Semin Oncol , vol.19 , pp. 646-662
    • Rowinsky, E.K.1    Onetto, N.2    Canetta, R.M.3    Arbuck, S.G.4
  • 23
    • 0030945754 scopus 로고    scopus 로고
    • Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1α,25-dihydroxyvitamin D3
    • Schmiedlin-Ren P, Thummel KE, Fisher JM, Paine MF, Lown KS and Watkins PB (1997) Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1α,25-dihydroxyvitamin D3. Mol Pharmacol 51:741-754.
    • (1997) Mol Pharmacol , vol.51 , pp. 741-754
    • Schmiedlin-Ren, P.1    Thummel, K.E.2    Fisher, J.M.3    Paine, M.F.4    Lown, K.S.5    Watkins, P.B.6
  • 24
  • 25
    • 0029764332 scopus 로고    scopus 로고
    • Assays of CYP2C8- and CYP3A4-mediated metabolism of taxol in vivo and in vitro
    • Walle T (1996) Assays of CYP2C8-and CYP3A4-mediated metabolism of taxol in vivo and in vitro. Methods Enzymol 272:145-151.
    • (1996) Methods Enzymol , vol.272 , pp. 145-151
    • Walle, T.1
  • 27
    • 0023588109 scopus 로고
    • Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man
    • Watkins PB, Wrighton SA, Schuetz EG, Molowa DT and Guzelian PS (1987) Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. J Clin Invest 80:1029-1036.
    • (1987) J Clin Invest , vol.80 , pp. 1029-1036
    • Watkins, P.B.1    Wrighton, S.A.2    Schuetz, E.G.3    Molowa, D.T.4    Guzelian, P.S.5
  • 28
    • 0029986922 scopus 로고    scopus 로고
    • Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers: Concentration- and dose-dependent absorption in vitro and in vivo
    • Wetterich U, Spahn-Langguth H, Mutschler E, Terhaag B, Rösch W and Langguth P (1996) Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers: Concentration-and dose-dependent absorption in vitro and in vivo. Pharm Res 13:514-522.
    • (1996) Pharm Res , vol.13 , pp. 514-522
    • Wetterich, U.1    Spahn-Langguth, H.2    Mutschler, E.3    Terhaag, B.4    Rösch, W.5    Langguth, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.