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Volumn 56, Issue 2, 1999, Pages 383-389

Interactions of HIV protease inhibitors with ATP-dependent drug export proteins

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CYCLOSPORIN A; FLUORESCEIN; GLYCOPROTEIN P; LEUKOTRIENE C4; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR;

EID: 0032765899     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.2.383     Document Type: Article
Times cited : (176)

References (34)
  • 1
    • 0031896882 scopus 로고    scopus 로고
    • Active apical secretory efflux of the HIV-protease inhibitors saquinavir and ritonavir in Caco-2 cell monolayers
    • Alsenz J, Steffen H and Alex R (1998) Active apical secretory efflux of the HIV-protease inhibitors saquinavir and ritonavir in Caco-2 cell monolayers. Pharm Res 15:423-428.
    • (1998) Pharm Res , vol.15 , pp. 423-428
    • Alsenz, J.1    Steffen, H.2    Alex, R.3
  • 2
    • 0033562673 scopus 로고    scopus 로고
    • HIV protease inhibitor ritonavir: A more potent inhibitor of P-glycoprotein than the cyclosporine analogue SDZ PSC-833
    • in press
    • Drewe J, Gutmann H, Fricker G, Török M, Beglinger C and Huwyler J (1999) HIV protease inhibitor ritonavir: A more potent inhibitor of P-glycoprotein than the cyclosporine analogue SDZ PSC-833. Biochem Pharmacol, in press.
    • (1999) Biochem Pharmacol
    • Drewe, J.1    Gutmann, H.2    Fricker, G.3    Török, M.4    Beglinger, C.5    Huwyler, J.6
  • 3
    • 0030852009 scopus 로고    scopus 로고
    • Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir
    • Eagling VA, Back DJ and Barry MG (1997) Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir. Br J Clin Pharmacol 44:190-194.
    • (1997) Br J Clin Pharmacol , vol.44 , pp. 190-194
    • Eagling, V.A.1    Back, D.J.2    Barry, M.G.3
  • 5
    • 84965184863 scopus 로고
    • Use of isolated renal tubules in the estimation of metabolic processes associated with active cellular transport
    • Forster RP and Taggart JV (1950) Use of isolated renal tubules in the estimation of metabolic processes associated with active cellular transport. J Cell Camp Physiol 36:251-270.
    • (1950) J Cell Camp Physiol , vol.36 , pp. 251-270
    • Forster, R.P.1    Taggart, J.V.2
  • 6
    • 0031946993 scopus 로고    scopus 로고
    • In vitro blood-brain barrier permeability of nevirapine compared to other HIV antiretroviral agents
    • Glynn SL and Yazdanian M (1998) In vitro blood-brain barrier permeability of nevirapine compared to other HIV antiretroviral agents. J Pharm Sci 87:306-310.
    • (1998) J Pharm Sci , vol.87 , pp. 306-310
    • Glynn, S.L.1    Yazdanian, M.2
  • 7
    • 0031933299 scopus 로고    scopus 로고
    • HIV-1 protease inhibitors in review
    • Hilgeroth A (1998) HIV-1 protease inhibitors in review. Pharm-Unserer-Zeit 27:22-25.
    • (1998) Pharm-unserer-zeit , vol.27 , pp. 22-25
    • Hilgeroth, A.1
  • 8
    • 0026500180 scopus 로고
    • The function of Gp170, the multidrug resistance gene product, in the brush border of rat intestine
    • Hsing S, Gatmaitan Z and Arias IA (1992) The function of Gp170, the multidrug resistance gene product, in the brush border of rat intestine. Gastroenterology 102:879-885.
    • (1992) Gastroenterology , vol.102 , pp. 879-885
    • Hsing, S.1    Gatmaitan, Z.2    Arias, I.A.3
  • 11
    • 0032518290 scopus 로고    scopus 로고
    • The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV1 protease inhibitors
    • Kim RB, Fromm MF, Wandel C, Leake B, Wood AJ, Roden DM and Wilkinson GR (1998) The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV1 protease inhibitors. J Clin Invest 101:289-294.
    • (1998) J Clin Invest , vol.101 , pp. 289-294
    • Kim, R.B.1    Fromm, M.F.2    Wandel, C.3    Leake, B.4    Wood, A.J.5    Roden, D.M.6    Wilkinson, G.R.7
  • 12
    • 0031790709 scopus 로고    scopus 로고
    • Metabolism of the human immunodeficiency virus protease inhibitors indinavir and ritonavir by human intestinal microsomes and expressed cytochrome P4503A4/3A5: Mechanism-based inactivation of cytochrome P4503A by ritonavir
    • Koudriakova T, Iatsimirskaia E, Utkin I, Gangl E, Vouros P, Storozhuk E, Orza D, Marinina J and Gerber N (1998) Metabolism of the human immunodeficiency virus protease inhibitors indinavir and ritonavir by human intestinal microsomes and expressed cytochrome P4503A4/3A5: Mechanism-based inactivation of cytochrome P4503A by ritonavir. Drug Metab Dispos 26:552-561.
    • (1998) Drug Metab Dispos , vol.26 , pp. 552-561
    • Koudriakova, T.1    Iatsimirskaia, E.2    Utkin, I.3    Gangl, E.4    Vouros, P.5    Storozhuk, E.6    Orza, D.7    Marinina, J.8    Gerber, N.9
  • 13
    • 0031691234 scopus 로고    scopus 로고
    • The role of P-glycoprotein and acanlicular multispecific organic anion transporter in the hepatobiliary excretion of drugs
    • Kusuhara H, Suzuki H and Sugiyama Y (1998) The role of P-glycoprotein and acanlicular multispecific organic anion transporter in the hepatobiliary excretion of drugs. J Pharm Sci 87:1025-1040.
    • (1998) J Pharm Sci , vol.87 , pp. 1025-1040
    • Kusuhara, H.1    Suzuki, H.2    Sugiyama, Y.3
  • 15
    • 0029912351 scopus 로고    scopus 로고
    • ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump
    • Leier I, Jedlitschky G, Buchholz U, Center M, Cole SP, Deeley RG and Keppler D (1996) ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump. Biochem J 314:433-437.
    • (1996) Biochem J , vol.314 , pp. 433-437
    • Leier, I.1    Jedlitschky, G.2    Buchholz, U.3    Center, M.4    Cole, S.P.5    Deeley, R.G.6    Keppler, D.7
  • 17
    • 0030738677 scopus 로고    scopus 로고
    • Multidrug resistance: Molecular mechanisms and clinical relevance
    • Ling V (1997) Multidrug resistance: Molecular mechanisms and clinical relevance. Cancer Chemother Pharmacol 40 (Suppl):S3-S8.
    • (1997) Cancer Chemother Pharmacol , vol.40 , Issue.SUPPL.
    • Ling, V.1
  • 18
    • 0031719032 scopus 로고    scopus 로고
    • Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells
    • Makhey VD, Guo A, Norris DA, Hu P and Sinko PJ (1998) Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells. Pharm Res 15:1160-1167.
    • (1998) Pharm Res , vol.15 , pp. 1160-1167
    • Makhey, V.D.1    Guo, A.2    Norris, D.A.3    Hu, P.4    Sinko, P.J.5
  • 20
    • 0030475336 scopus 로고    scopus 로고
    • Multiple pathways of organic anion secretion in renal proximal tubule revealed by confocal microscopy
    • Masereeuw R, Russel FG and Miller DS (1996) Multiple pathways of organic anion secretion in renal proximal tubule revealed by confocal microscopy. Am J Physiol 271:F1173-F1182.
    • (1996) Am J Physiol , vol.271
    • Masereeuw, R.1    Russel, F.G.2    Miller, D.S.3
  • 21
    • 0029092601 scopus 로고
    • Daunomycin secretion by killfish renal proximal tubules
    • Miller DS (1995) Daunomycin secretion by killfish renal proximal tubules. Am J Physiol 269:R370-R379.
    • (1995) Am J Physiol , vol.269
    • Miller, D.S.1
  • 22
    • 0023160940 scopus 로고
    • Aquatic models for the study of renal transport function and pollutant toxicity
    • Miller DS (1987) Aquatic models for the study of renal transport function and pollutant toxicity. Environ-Health-Perspect 71:59-68.
    • (1987) Environ-health-perspect , vol.71 , pp. 59-68
    • Miller, D.S.1
  • 24
    • 0026350903 scopus 로고
    • Indirect coupling of organic anion secretion to sodium in teleost (Paralichthys lethostigma) renal tubules
    • Miller DS and Pritchard JB (1991) Indirect coupling of organic anion secretion to sodium in teleost (Paralichthys lethostigma) renal tubules. Am J Physiol 261: R1470-R1477.
    • (1991) Am J Physiol , vol.261
    • Miller, D.S.1    Pritchard, J.B.2
  • 25
    • 0031543441 scopus 로고    scopus 로고
    • Dual pathways for organic anion secretion in renal proximal tubule
    • Miller DS and Pritchard JB (1997) Dual pathways for organic anion secretion in renal proximal tubule. J Exp Zool 279:462-470.
    • (1997) J Exp Zool , vol.279 , pp. 462-470
    • Miller, D.S.1    Pritchard, J.B.2
  • 26
    • 0030753125 scopus 로고    scopus 로고
    • Molecular aspects of hepatobiliary transport
    • Muller M and Jansen PLM (1997) Molecular aspects of hepatobiliary transport. Am J Physiol 272:G1285-G1303.
    • (1997) Am J Physiol , vol.272
    • Muller, M.1    Jansen, P.L.M.2
  • 27
    • 0027133590 scopus 로고
    • Mechanisms mediating renal secretion of organic anions and cations
    • Pritchard JB and Miller DS (1993) Mechanisms mediating renal secretion of organic anions and cations. Physiol Rev 73:765-796.
    • (1993) Physiol Rev , vol.73 , pp. 765-796
    • Pritchard, J.B.1    Miller, D.S.2
  • 28
    • 0030762825 scopus 로고    scopus 로고
    • Protease inhibitor therapy in children with perinatally acquired HIV infection
    • Rutstein RM, Feingold A, Meislich D, Word B and Rudy B (1997) Protease inhibitor therapy in children with perinatally acquired HIV infection. AIDS 11:107-111.
    • (1997) AIDS , vol.11 , pp. 107-111
    • Rutstein, R.M.1    Feingold, A.2    Meislich, D.3    Word, B.4    Rudy, B.5
  • 29
    • 0030832802 scopus 로고    scopus 로고
    • Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules
    • Schaub TP, Kartenbeck J, Konig J, Vogel O, Witzgall R, Kriz W and Keppler D (1997) Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules. J Am Soc Nephrol 8:1213-1221.
    • (1997) J Am Soc Nephrol , vol.8 , pp. 1213-1221
    • Schaub, T.P.1    Kartenbeck, J.2    Konig, J.3    Vogel, O.4    Witzgall, R.5    Kriz, W.6    Keppler, D.7
  • 30
    • 27244461958 scopus 로고
    • P-glycoprotein mediated transport of a fluorescent cyclosporin analogue in teleost proximal tubules
    • Schramm U, Fricker G, Wenger R and Miller DS (1995) P-glycoprotein mediated transport of a fluorescent cyclosporin analogue in teleost proximal tubules. Am J Physiol 268:F46-F52.
    • (1995) Am J Physiol , vol.268
    • Schramm, U.1    Fricker, G.2    Wenger, R.3    Miller, D.S.4
  • 31
    • 0025023586 scopus 로고
    • Fluorescein transport in isolated proximal tubules in vitro: Epifluorometric analysis
    • Sullivan LP, Grantham JA, Rome L, Wallace D and Grantham JJ (1990) Fluorescein transport in isolated proximal tubules in vitro: Epifluorometric analysis. Am J Physiol 258:F46-F51.
    • (1990) Am J Physiol , vol.258
    • Sullivan, L.P.1    Grantham, J.A.2    Rome, L.3    Wallace, D.4    Grantham, J.J.5
  • 32
    • 0000563050 scopus 로고
    • Heat shock-stimulated transepithelial daunomycin secretion by renal proximal tubule primary cultures
    • Sussman-Turner CS and Renfro JL (1994) Heat shock-stimulated transepithelial daunomycin secretion by renal proximal tubule primary cultures. Am J Physiol 267:F135-F144.
    • (1994) Am J Physiol , vol.267
    • Sussman-Turner, C.S.1    Renfro, J.L.2
  • 34
    • 0031002002 scopus 로고    scopus 로고
    • Side-effects of ritonavir and its combination with saquinavir with special regard to renal function
    • Witzke O, Plentz A, Schafers RF, Reinhardt W, Heemann U and Philipp T (1997) Side-effects of ritonavir and its combination with saquinavir with special regard to renal function (Letter). AIDS 11:836-838.
    • (1997) AIDS , vol.11 , pp. 836-838
    • Witzke, O.1    Plentz, A.2    Schafers, R.F.3    Reinhardt, W.4    Heemann, U.5    Philipp, T.6


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