Mechanisms of Cefadroxil Uptake in the Choroid Plexus: Studies in Wild-Type and PEPT2 Knockout Mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 308, Issue 2, 2004, Pages 462-467

  Ocheltree, Scott M ^a   Shen, Hong ^a   Hu, Yongjun ^a   Xiang, Jianming ^b   Keep, Richard F ^b   Smith, David E ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOHIPPURIC ACID; ANTIINFECTIVE AGENT; CARRIER PROTEIN; CEFADROXIL; COTRANSPORTER; GLYCYLSARCOSINE; HYDROGEN COUPLED OLIGOPEPTIDE TRANSPORTER PEPT2; HYDROGEN-COUPLED OLIGOPEPTIDE TRANSPORTER PEPT2; ORGANIC ANION TRANSPORTER; PEPTIDE TRANSPORTER 2; UNCLASSIFIED DRUG;

ACTIVE TRANSPORT; ANIMAL; ANIMAL TISSUE; ARTICLE; CEREBROSPINAL FLUID; CHOROID PLEXUS; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLEARANCE; DRUG UPTAKE; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; MOUSE MUTANT; NONHUMAN; PH; PRIORITY JOURNAL; TEMPERATURE; TEMPERATURE DEPENDENCE; TIME; WILD TYPE;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOLOGICAL TRANSPORT, ACTIVE; CEFADROXIL; CHOROID PLEXUS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN-ION CONCENTRATION; MICE; MICE, KNOCKOUT; SYMPORTERS; TEMPERATURE; TIME FACTORS;

EID: 1542771649     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.060400     Document Type: Article

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