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Volumn 54, Issue 2, 1998, Pages 342-352

Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1 METHYLNICOTINAMIDE; AMANTADINE; CARRIER PROTEIN; CATION; CHOLINE; COMPLEMENTARY DNA; DOPAMINE; HISTAMINE; MEMANTINE; NEUROTRANSMITTER; NORADRENALIN; SEROTONIN; TETRYLAMMONIUM;

EID: 0031824347     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.54.2.342     Document Type: Article
Times cited : (313)

References (40)
  • 3
    • 0021089452 scopus 로고
    • Aetiology of Parkinson's disease
    • Calne DB and Langston JW (1983) Aetiology of Parkinson's disease. Lancet 2:1457-1459.
    • (1983) Lancet , vol.2 , pp. 1457-1459
    • Calne, D.B.1    Langston, J.W.2
  • 4
    • 0026564448 scopus 로고
    • Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: Therapeutic advantage against NMDA receptor-mediated neurotoxicity
    • Chen H-SV, Pellegrini JW, Aggarwal SK, Lei SZ, Warach S, Jensen FE, and Lipton SA (1992) Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci 12:4427-4436.
    • (1992) J Neurosci , vol.12 , pp. 4427-4436
    • Chen, H.-S.V.1    Pellegrini, J.W.2    Aggarwal, S.K.3    Lei, S.Z.4    Warach, S.5    Jensen, F.E.6    Lipton, S.A.7
  • 5
    • 0021893795 scopus 로고
    • Primate model of parkinsonism: Selective lesion of nigrostriatal neurons by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces an extrapyramidal syndrome in rhesus monkeys
    • Chiueh CC, Burns RS, Markey SP, Jacobowitz DM, and Kopin IJ (1985) Primate model of parkinsonism: selective lesion of nigrostriatal neurons by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces an extrapyramidal syndrome in rhesus monkeys. Life Sci 36:213-218.
    • (1985) Life Sci , vol.36 , pp. 213-218
    • Chiueh, C.C.1    Burns, R.S.2    Markey, S.P.3    Jacobowitz, D.M.4    Kopin, I.J.5
  • 6
  • 7
    • 0027049060 scopus 로고
    • Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
    • Giros B, El Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, and Caron MG (1992) Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. Mol Pharmacol 42:383-390.
    • (1992) Mol Pharmacol , vol.42 , pp. 383-390
    • Giros, B.1    El Mestikawy, S.2    Godinot, N.3    Zheng, K.4    Han, H.5    Yang-Feng, T.6    Caron, M.G.7
  • 9
    • 0013895415 scopus 로고
    • The early stages of absoprtion of injected horseradish peroxidase in the proximal tubules of mouse kidney: Ultrastructural cytochemistry by a new technique
    • Graham RC Jr and Karnovsky MJ (1966) The early stages of absoprtion of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. J Histochem Cytochem 14:291-302.
    • (1966) J Histochem Cytochem , vol.14 , pp. 291-302
    • Graham Jr., R.C.1    Karnovsky, M.J.2
  • 10
    • 0014939890 scopus 로고
    • Amantadine-dopamine interaction: Possible mode of action in parkinsonism
    • Grelak RP, Clark R, Stump JM, and Vernier VG (1970) Amantadine-dopamine interaction: possible mode of action in parkinsonism. Science (Washington DC) 169:203-204.
    • (1970) Science (Washington DC) , vol.169 , pp. 203-204
    • Grelak, R.P.1    Clark, R.2    Stump, J.M.3    Vernier, V.G.4
  • 14
    • 0023576260 scopus 로고
    • The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (MPTP) and its relevance to Parkinson's disease
    • Kinemuchi H, Fowler CJ, and Tipton KF (1987) The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (MPTP) and its relevance to Parkinson's disease. Neurochem Int 11:359-373.
    • (1987) Neurochem Int , vol.11 , pp. 359-373
    • Kinemuchi, H.1    Fowler, C.J.2    Tipton, K.F.3
  • 15
    • 0031410948 scopus 로고    scopus 로고
    • The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26
    • Koehler MR, Wissinger B, Gorboulev V, Koepsell H, and Schmid M (1997) The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26. Cytogenet Cell Genet 79:198-200.
    • (1997) Cytogenet Cell Genet , vol.79 , pp. 198-200
    • Koehler, M.R.1    Wissinger, B.2    Gorboulev, V.3    Koepsell, H.4    Schmid, M.5
  • 16
    • 0031893146 scopus 로고    scopus 로고
    • Organic cation transporters in intestine, kidney, liver, and brain
    • Koepsell H (1998) Organic cation transporters in intestine, kidney, liver, and brain. Annu Rev Physiol 60:243-266.
    • (1998) Annu Rev Physiol , vol.60 , pp. 243-266
    • Koepsell, H.1
  • 17
    • 0025801041 scopus 로고
    • Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: A human postmortem brain study
    • Kornhuber J, Bormann J, Hübers M, Rusche K, and Riederer P (1991) Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study. Eur J Pharmacol 206:297-300.
    • (1991) Eur J Pharmacol , vol.206 , pp. 297-300
    • Kornhuber, J.1    Bormann, J.2    Hübers, M.3    Rusche, K.4    Riederer, P.5
  • 20
    • 0027507306 scopus 로고
    • A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport
    • Marger MD and Saier MH Jr (1993) A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Trends Biochem Sci 18:13-20.
    • (1993) Trends Biochem Sci , vol.18 , pp. 13-20
    • Marger, M.D.1    Saier Jr., M.H.2
  • 23
    • 0030590117 scopus 로고    scopus 로고
    • cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2
    • Okuda M, Saito H, Urakami Y, Takano M, and Inui K-I (1996) cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2. Biochem Biophys Res Commun 224:500-507.
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 500-507
    • Okuda, M.1    Saito, H.2    Urakami, Y.3    Takano, M.4    Inui, K.-I.5
  • 24
    • 0016249095 scopus 로고
    • Amantadine
    • Parkes D (1974) Amantadine. Adv Drug Res 8:11-81.
    • (1974) Adv Drug Res , vol.8 , pp. 11-81
    • Parkes, D.1
  • 25
    • 0024313055 scopus 로고
    • Sodium-independent transport of noradrenaline in mouse and rat astrocytes in primary culture
    • Paterson IA and Hertz L (1989) Sodium-independent transport of noradrenaline in mouse and rat astrocytes in primary culture. J Neurosci Res 23:71-77.
    • (1989) J Neurosci Res , vol.23 , pp. 71-77
    • Paterson, I.A.1    Hertz, L.2
  • 27
    • 0027364736 scopus 로고
    • From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters
    • Rudnick G and Clark J (1993) From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters. Biochim Biophys Acta 1144:249-263.
    • (1993) Biochim Biophys Acta , vol.1144 , pp. 249-263
    • Rudnick, G.1    Clark, J.2
  • 28
    • 0030254655 scopus 로고    scopus 로고
    • The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters
    • Schweifer N and Barlow DP (1996) The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters. Mammalian Genome 7:735-740.
    • (1996) Mammalian Genome , vol.7 , pp. 735-740
    • Schweifer, N.1    Barlow, D.P.2
  • 29
    • 0025284551 scopus 로고
    • Dopamine receptors and transporters in Parkinson's disease and schizophrenia
    • Seeman P and Niznik HB (1990) Dopamine receptors and transporters in Parkinson's disease and schizophrenia. FASEB J 4:2737-2744.
    • (1990) FASEB J , vol.4 , pp. 2737-2744
    • Seeman, P.1    Niznik, H.B.2
  • 30
    • 0030855487 scopus 로고    scopus 로고
    • Expression cloning and characterization of a novel multispecific organic anion transporter
    • Sekine T, Watanabe N, Hosoyamada M, Kanai Y, and Endou H (1997) Expression cloning and characterization of a novel multispecific organic anion transporter. J Biol Chem 272:18526-18529.
    • (1997) J Biol Chem , vol.272 , pp. 18526-18529
    • Sekine, T.1    Watanabe, N.2    Hosoyamada, M.3    Kanai, Y.4    Endou, H.5
  • 31
    • 0022633481 scopus 로고
    • MPTP: A neurotoxin relevant to the pathophysiology of Parkinson's disease
    • Snyder SH and D'Amato RJ (1986) MPTP: a neurotoxin relevant to the pathophysiology of Parkinson's disease. Neurology 36:250-258.
    • (1986) Neurology , vol.36 , pp. 250-258
    • Snyder, S.H.1    D'Amato, R.J.2
  • 32
    • 0031036030 scopus 로고    scopus 로고
    • Multiple ionic conductances of the human dopamine transporter: The actions of dopamine and psychostimulants
    • Sonders MS, Zhu SJ, Zahniser NR, Kavanaugh MP, and Amara SG (1997) Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants. J Neurosci 17:960-974.
    • (1997) J Neurosci , vol.17 , pp. 960-974
    • Sonders, M.S.1    Zhu, S.J.2    Zahniser, N.R.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 34
    • 0015584089 scopus 로고
    • The effect of amantadine on radiolabeled biogenic amines in the rat brain
    • Symchowicz S, Korduba CA, and Veals J (1973) The effect of amantadine on radiolabeled biogenic amines in the rat brain. Eur J Pharmacol 21:155-160.
    • (1973) Eur J Pharmacol , vol.21 , pp. 155-160
    • Symchowicz, S.1    Korduba, C.A.2    Veals, J.3
  • 36
    • 0027504297 scopus 로고
    • Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
    • Tipton KF and Singer TP (1993) Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J Neurochem 61:1191-1206.
    • (1993) J Neurochem , vol.61 , pp. 1191-1206
    • Tipton, K.F.1    Singer, T.P.2
  • 37
    • 0000841295 scopus 로고
    • The extraneuronal uptake and metabolism of catecholamines
    • (U Trendelenburg and N Weiners, eds.) Springer, Berlin
    • Trendelenburg U (1988) The extraneuronal uptake and metabolism of catecholamines, in Handbook of Experimental Pharmacology, Vol 90 (U Trendelenburg and N Weiners, eds.) pp 279-319, Springer, Berlin.
    • (1988) Handbook of Experimental Pharmacology , vol.90 , pp. 279-319
    • Trendelenburg, U.1
  • 38
    • 0015721255 scopus 로고
    • High affinity transport of choline into synaptosomes of rat brain
    • Yamamura HI and Snyder SH (1973) High affinity transport of choline into synaptosomes of rat brain. J Neurochem 21:1355-1374.
    • (1973) J Neurochem , vol.21 , pp. 1355-1374
    • Yamamura, H.I.1    Snyder, S.H.2
  • 39
    • 0030985189 scopus 로고    scopus 로고
    • Cloning and functional characterization of a rat renal organic cation transporter isoform (rOCT1A)
    • Zhang L, Dresser MJ, Chun JK, Babbitt PC, and Giacomini KM (1997a) Cloning and functional characterization of a rat renal organic cation transporter isoform (rOCT1A). J Biol Chem 272:16548-16554.
    • (1997) J Biol Chem , vol.272 , pp. 16548-16554
    • Zhang, L.1    Dresser, M.J.2    Chun, J.K.3    Babbitt, P.C.4    Giacomini, K.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.