-
2
-
-
3042762534
-
Nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase
-
Sharma PL, Nurpeisov V, Hernandez-Santiago B, et al. Nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. Curr Top Med Chem 2004; 4 (9): 895-919
-
(2004)
Curr Top Med Chem
, vol.4
, Issue.9
, pp. 895-919
-
-
Sharma, P.L.1
Nurpeisov, V.2
Hernandez-Santiago, B.3
-
3
-
-
4444309793
-
New nucleoside/nucleotide backbone options: A review of recent studies
-
Ruane PJ, DeJesus E. New nucleoside/nucleotide backbone options: a review of recent studies. J Acquir Immune Defic Syndr 2004; 37: S21-9
-
(2004)
J Acquir Immune Defic Syndr
, vol.37
-
-
Ruane, P.J.1
DeJesus, E.2
-
4
-
-
2942524068
-
Current status of the non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1
-
Balzarini J. Current status of the non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1. Curr Top Med Chem 2004; 4 (9): 921-44
-
(2004)
Curr Top Med Chem
, vol.4
, Issue.9
, pp. 921-944
-
-
Balzarini, J.1
-
5
-
-
2942534993
-
HIV protease inhibition: Limited recent progress and advances in understanding current pitfalls
-
Rodriguez-Barrios F, Gago F. HIV protease inhibition: limited recent progress and advances in understanding current pitfalls. Curr Top Med Chem 2004; 4 (9): 991-1007
-
(2004)
Curr Top Med Chem
, vol.4
, Issue.9
, pp. 991-1007
-
-
Rodriguez-Barrios, F.1
Gago, F.2
-
6
-
-
2442548462
-
Antiretrovirals, part 1: Overview, history, and focus on protease inhibitors
-
Wynn GH, Zapor MJ, Smith BH, et al. Antiretrovirals, part 1: overview, history, and focus on protease inhibitors. Psychosomatics 2004; 45 (3): 262-70
-
(2004)
Psychosomatics
, vol.45
, Issue.3
, pp. 262-270
-
-
Wynn, G.H.1
Zapor, M.J.2
Smith, B.H.3
-
7
-
-
9144250943
-
Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine
-
Gulick RM, Meibohm A, Havlir D, et al. Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine. AIDS 2003; 17 (16): 2345-9
-
(2003)
AIDS
, vol.17
, Issue.16
, pp. 2345-2349
-
-
Gulick, R.M.1
Meibohm, A.2
Havlir, D.3
-
8
-
-
11144355711
-
Long-term safety and durable antiretroviral activity of lopinavir/ritonavir in treatment-naive patients: 4 Year follow-up study
-
Hicks C, King MS, Gulick RM, et al. Long-term safety and durable antiretroviral activity of lopinavir/ritonavir in treatment-naive patients: 4 year follow-up study. AIDS 2004; 18 (5): 775-9
-
(2004)
AIDS
, vol.18
, Issue.5
, pp. 775-779
-
-
Hicks, C.1
King, M.S.2
Gulick, R.M.3
-
9
-
-
0442268112
-
A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less: AIDS Clinical Trials Group 320 Study Team
-
Hammer SM, Squires KE, Hughes MD, et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less: AIDS Clinical Trials Group 320 Study Team. N Engl J Med 1997; 337 (11): 725-33
-
(1997)
N Engl J Med
, vol.337
, Issue.11
, pp. 725-733
-
-
Hammer, S.M.1
Squires, K.E.2
Hughes, M.D.3
-
10
-
-
0030869269
-
Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy
-
Gulick RM, Mellors JW, Havlir D, et al. Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med 1997; 337 (11): 734-9
-
(1997)
N Engl J Med
, vol.337
, Issue.11
, pp. 734-739
-
-
Gulick, R.M.1
Mellors, J.W.2
Havlir, D.3
-
11
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection: HIV Outpatient Study Investigators
-
Palella Jr FJ, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection: HIV Outpatient Study Investigators. N Engl J Med 1998; 338 (13): 853-60
-
(1998)
N Engl J Med
, vol.338
, Issue.13
, pp. 853-860
-
-
Palella Jr., F.J.1
Delaney, K.M.2
Moorman, A.C.3
-
12
-
-
2942529150
-
The epidemiology of antiretroviral drug resistance among drug-naive HIV-1-infectbility ed persons in 10 US cities
-
Weinstock HS, Zaidi I, Heneine W, et al. The epidemiology of antiretroviral drug resistance among drug-naive HIV-1-infectbility ed persons in 10 US cities. J Infect Dis 2004; 189 (12): 2174-80
-
(2004)
J Infect Dis
, vol.189
, Issue.12
, pp. 2174-2180
-
-
Weinstock, H.S.1
Zaidi, I.2
Heneine, W.3
-
13
-
-
0034062972
-
Antiretroviral resistance testing comes of age
-
Hammer SM, Pedneault L. Antiretroviral resistance testing comes of age. Antivir Ther 2000; 5 (1): 23-6
-
(2000)
Antivir Ther
, vol.5
, Issue.1
, pp. 23-26
-
-
Hammer, S.M.1
Pedneault, L.2
-
14
-
-
0034074743
-
Prevalence of genotypic and phenotypic resistance to anti-retroviral drugs in a cohort of therapy-naive HIV-1 infected US military personnel
-
Wegner SA, Brodine SK, Mascola JR, et al. Prevalence of genotypic and phenotypic resistance to anti-retroviral drugs in a cohort of therapy-naive HIV-1 infected US military personnel. AIDS 2000; 14 (8): 1009-15
-
(2000)
AIDS
, vol.14
, Issue.8
, pp. 1009-1015
-
-
Wegner, S.A.1
Brodine, S.K.2
Mascola, J.R.3
-
15
-
-
0037043652
-
Antiretroviral-drug resistance among patients recently infected with HIV
-
Little SJ, Holte S, Routy JP, et al. Antiretroviral-drug resistance among patients recently infected with HIV. N Engl J Med 2002; 347 (6): 385-94
-
(2002)
N Engl J Med
, vol.347
, Issue.6
, pp. 385-394
-
-
Little, S.J.1
Holte, S.2
Routy, J.P.3
-
16
-
-
4544381403
-
HIV fusion and its inhibition in antiretroviral therapy
-
Greenberg M, Cammack N, Salgo M, et al. HIV fusion and its inhibition in antiretroviral therapy. Rev Med Virol 2004; 14 (5): 321-37
-
(2004)
Rev Med Virol
, vol.14
, Issue.5
, pp. 321-337
-
-
Greenberg, M.1
Cammack, N.2
Salgo, M.3
-
17
-
-
0141814730
-
The entry of entry inhibitors: A fusion of science and medicine
-
Moore JP, Doms RW. The entry of entry inhibitors: a fusion of science and medicine. Proc Natl Acad Sci U S A 2003; 100 (19): 10598-602
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.19
, pp. 10598-10602
-
-
Moore, J.P.1
Doms, R.W.2
-
18
-
-
2942627670
-
HIV-chemotherapy and -prophylaxis: New drugs, leads and approaches
-
De Clercq E. HIV-chemotherapy and -prophylaxis: new drugs, leads and approaches. Int J Biochem Cell Biol 2004; 36 (9): 1800-22
-
(2004)
Int J Biochem Cell Biol
, vol.36
, Issue.9
, pp. 1800-1822
-
-
De Clercq, E.1
-
19
-
-
0041488800
-
Small-molecule HIV-1 integrase inhibitors: The 2001-2002 update
-
Dayam R, Neamati N. Small-molecule HIV-1 integrase inhibitors: the 2001-2002 update. Curr Pharm Des 2003; 9 (22): 1789-802
-
(2003)
Curr Pharm des
, vol.9
, Issue.22
, pp. 1789-1802
-
-
Dayam, R.1
Neamati, N.2
-
20
-
-
1842843662
-
HIV-1 entry inhibitors: Closing the front door
-
Tomkowicz B, Collman RG. HIV-1 entry inhibitors: closing the front door. Expert Opin Ther Targets 2004; 8 (2): 65-78
-
(2004)
Expert Opin Ther Targets
, vol.8
, Issue.2
, pp. 65-78
-
-
Tomkowicz, B.1
Collman, R.G.2
-
21
-
-
0346025452
-
Clinical development of microbicides for the prevention of HIV infection
-
D'Cruz OJ, Uckun FM. Clinical development of microbicides for the prevention of HIV infection. Curr Pharm Des 2004; 10 (3): 315-36
-
(2004)
Curr Pharm des
, vol.10
, Issue.3
, pp. 315-336
-
-
D'Cruz, O.J.1
Uckun, F.M.2
-
22
-
-
0345569681
-
Inhibiting sexual transmission of HIV-1 infection
-
Shattock RJ, Moore JP. Inhibiting sexual transmission of HIV-1 infection. Nat Rev Microbiol 2003; 1 (1): 25-34
-
(2003)
Nat Rev Microbiol
, vol.1
, Issue.1
, pp. 25-34
-
-
Shattock, R.J.1
Moore, J.P.2
-
23
-
-
3042799382
-
Prospects of HIV-1 entry inhibitors as novel therapeutics
-
Pierson TC, Doms RW, Pohlmann S. Prospects of HIV-1 entry inhibitors as novel therapeutics. Rev Med Virol 2004; 14 (4): 255-70
-
(2004)
Rev Med Virol
, vol.14
, Issue.4
, pp. 255-270
-
-
Pierson, T.C.1
Doms, R.W.2
Pohlmann, S.3
-
24
-
-
0034675998
-
HIV-1 membrane fusion: Targets of opportunity
-
Doms RW, Moore JP. HIV-1 membrane fusion: targets of opportunity. J Cell Biol 2000; 151 (2): F9-14
-
(2000)
J Cell Biol
, vol.151
, Issue.2
-
-
Doms, R.W.1
Moore, J.P.2
-
25
-
-
0001914545
-
Chemokine receptors and HIV entry
-
Doms RW. Chemokine receptors and HIV entry. AIDS 2001; 15 Suppl. 1: S34-5
-
(2001)
AIDS
, vol.15
, Issue.1 SUPPL.
-
-
Doms, R.W.1
-
27
-
-
0035919703
-
The role of DC-SIGN and DC-SIGNR in HIV and SIV attachment, infection, and transmission
-
Baribaud F, Pohlmann S, Doms RW. The role of DC-SIGN and DC-SIGNR in HIV and SIV attachment, infection, and transmission. Virology 2001; 286 (1): 1-6
-
(2001)
Virology
, vol.286
, Issue.1
, pp. 1-6
-
-
Baribaud, F.1
Pohlmann, S.2
Doms, R.W.3
-
28
-
-
84943227304
-
The role of chemokine receptors in HIV infection of host cells
-
Bradshaw RA, Dennis EA, editors. New York: Academic Press
-
Reeves JD, Doms RW. The role of chemokine receptors in HIV infection of host cells. In: Bradshaw RA, Dennis EA, editors. Handbook of cell signaling. New York: Academic Press, 2003: 191-6
-
(2003)
Handbook of Cell Signaling
, pp. 191-196
-
-
Reeves, J.D.1
Doms, R.W.2
-
29
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
Berger EA, Murphy PM, Farber JM. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu Rev Immunol 1999; 17: 657-700
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
Murphy, P.M.2
Farber, J.M.3
-
30
-
-
0030970693
-
Core structure of gp41 from the HIV envelope glycoprotein
-
Chan DC, Fass D, Berger JM, et al. Core structure of gp41 from the HIV envelope glycoprotein. Cell 1997; 89 (2): 263-73
-
(1997)
Cell
, vol.89
, Issue.2
, pp. 263-273
-
-
Chan, D.C.1
Fass, D.2
Berger, J.M.3
-
31
-
-
0030962291
-
Atomic structure of the ectodomain from HIV-1 gp41
-
Weissenhorn W, Dessen A, Harrison SC, et al. Atomic structure of the ectodomain from HIV-1 gp41. Nature 1997; 387 (6631): 426-30
-
(1997)
Nature
, vol.387
, Issue.6631
, pp. 426-430
-
-
Weissenhorn, W.1
Dessen, A.2
Harrison, S.C.3
-
32
-
-
0034675886
-
Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion
-
Melikyan GB, Markosyan RM, Hemmati H, et al. Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion. J Cell Biol 2000; 151 (2): 413-23
-
(2000)
J Cell Biol
, vol.151
, Issue.2
, pp. 413-423
-
-
Melikyan, G.B.1
Markosyan, R.M.2
Hemmati, H.3
-
33
-
-
0033941573
-
Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1
-
Kuhmann SE, Platt EJ, Kozak SL, et al. Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1. J Virol 2000; 74 (15): 7005-15
-
(2000)
J Virol
, vol.74
, Issue.15
, pp. 7005-7015
-
-
Kuhmann, S.E.1
Platt, E.J.2
Kozak, S.L.3
-
34
-
-
0037223692
-
Baseline susceptibility of primary human immunodeficiency virus type 1 to entry inhibitors
-
Labrosse B, Labernardiere JL, Dam E, et al. Baseline susceptibility of primary human immunodeficiency virus type 1 to entry inhibitors. J Virol 2003; 77 (2): 1610-3
-
(2003)
J Virol
, vol.77
, Issue.2
, pp. 1610-1613
-
-
Labrosse, B.1
Labernardiere, J.L.2
Dam, E.3
-
35
-
-
0037059049
-
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
-
Reeves JD, Gallo SA, Ahmad N, et al. Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proc Natl Acad Sci U S A 2002; 99 (25): 16249-54
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.25
, pp. 16249-16254
-
-
Reeves, J.D.1
Gallo, S.A.2
Ahmad, N.3
-
36
-
-
2342514225
-
Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity
-
Reeves JD, Miamidian JL, Biscone MJ, et al. Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity. J Virol 2004; 78 (10): 5476-85
-
(2004)
J Virol
, vol.78
, Issue.10
, pp. 5476-5485
-
-
Reeves, J.D.1
Miamidian, J.L.2
Biscone, M.J.3
-
37
-
-
16244380203
-
Enfuvirtide resistance mutations: Impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization
-
Reeves JD, Lee FH, Miamidian JL, et al. Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization. J Virol 2005; 79 (8): 4991-9
-
(2005)
J Virol
, vol.79
, Issue.8
, pp. 4991-4999
-
-
Reeves, J.D.1
Lee, F.H.2
Miamidian, J.L.3
-
38
-
-
0033856458
-
Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120
-
Derdeyn CA, Decker JM, Sfakianos JN, et al. Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J Virol 2000; 74 (18): 8358-67
-
(2000)
J Virol
, vol.74
, Issue.18
, pp. 8358-8367
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
-
39
-
-
0034890660
-
Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor
-
Derdeyn CA, Decker JM, Sfakianos JN, et al. Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. J Virol 2001; 75 (18): 8605-14
-
(2001)
J Virol
, vol.75
, Issue.18
, pp. 8605-8614
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
-
40
-
-
0942290559
-
Natural variation of drug susceptibility in wild-type human immunodeficiency virus type 1
-
Parkin NT, Hellmann NS, Whitcomb JM, et al. Natural variation of drug susceptibility in wild-type human immunodeficiency virus type 1. Antimicrob Agents Chemother 2004; 48 (2): 437-43
-
(2004)
Antimicrob Agents Chemother
, vol.48
, Issue.2
, pp. 437-443
-
-
Parkin, N.T.1
Hellmann, N.S.2
Whitcomb, J.M.3
-
41
-
-
0026019437
-
Dextran sulfate blocks antibody binding to the principal neutralizing domain of human immunodeficiency virus type 1 without interfering with gp120-CD4 interactions
-
Callahan LN, Phelan M, Mallinson M, et al. Dextran sulfate blocks antibody binding to the principal neutralizing domain of human immunodeficiency virus type 1 without interfering with gp120-CD4 interactions. J Virol 1991; 65 (3): 1543-50
-
(1991)
J Virol
, vol.65
, Issue.3
, pp. 1543-1550
-
-
Callahan, L.N.1
Phelan, M.2
Mallinson, M.3
-
42
-
-
0033920212
-
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120
-
Moulard M, Lortat-Jacob H, Mondor I, et al. Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120. J Virol 2000; 74 (4): 1948-60
-
(2000)
J Virol
, vol.74
, Issue.4
, pp. 1948-1960
-
-
Moulard, M.1
Lortat-Jacob, H.2
Mondor, I.3
-
43
-
-
0032921247
-
Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120
-
Esser MT, Mori T, Mondor I, et al. Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120. J Virol 1999; 73 (5): 4360-71
-
(1999)
J Virol
, vol.73
, Issue.5
, pp. 4360-4371
-
-
Esser, M.T.1
Mori, T.2
Mondor, I.3
-
44
-
-
0037072880
-
Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
-
Botos I, O'Keefe BR, Shenoy SR, et al. Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides. J Biol Chem 2002; 277 (37): 34336-42
-
(2002)
J Biol Chem
, vol.277
, Issue.37
, pp. 34336-34342
-
-
Botos, I.1
O'Keefe, B.R.2
Shenoy, S.R.3
-
45
-
-
0033997468
-
Multiple antiviral activities of cyanovirin-N: Blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped viruses
-
Dey B, Lerner DL, Lusso P, et al. Multiple antiviral activities of cyanovirin-N: blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped viruses. J Virol 2000; 74 (10): 4562-9
-
(2000)
J Virol
, vol.74
, Issue.10
, pp. 4562-4569
-
-
Dey, B.1
Lerner, D.L.2
Lusso, P.3
-
46
-
-
0030790094
-
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: Potential applications to microbicide development
-
Boyd MR, Gustafson KR, McMahon JB, et al. Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. Antimicrob Agents Chemother 1997; 41 (7): 1521-30
-
(1997)
Antimicrob Agents Chemother
, vol.41
, Issue.7
, pp. 1521-1530
-
-
Boyd, M.R.1
Gustafson, K.R.2
McMahon, J.B.3
-
47
-
-
0036051788
-
Considerations and development of topical microbicides to inhibit the sexual transmission of HIV
-
Turpin JA. Considerations and development of topical microbicides to inhibit the sexual transmission of HIV. Expert Opin Investig Drugs 2002; 11 (8): 1077-97
-
(2002)
Expert Opin Investig Drugs
, vol.11
, Issue.8
, pp. 1077-1097
-
-
Turpin, J.A.1
-
48
-
-
0031985314
-
Spontaneous mutations in the env gene of the human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype
-
Dumonceaux J, Nisole S, Chanel C, et al. Spontaneous mutations in the env gene of the human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype. J Virol 1998; 72 (1): 512-9
-
(1998)
J Virol
, vol.72
, Issue.1
, pp. 512-519
-
-
Dumonceaux, J.1
Nisole, S.2
Chanel, C.3
-
49
-
-
0032880105
-
Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication
-
Kolchinsky P, Mirzabekov T, Farzan M, et al. Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication. J Virol 1999; 73 (10): 8120-6
-
(1999)
J Virol
, vol.73
, Issue.10
, pp. 8120-8126
-
-
Kolchinsky, P.1
Mirzabekov, T.2
Farzan, M.3
-
50
-
-
0032712246
-
Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity
-
LaBranche CC, Hoffman TL, Romano J, et al. Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity. J Virol 1999; 73 (12): 10310-9
-
(1999)
J Virol
, vol.73
, Issue.12
, pp. 10310-10319
-
-
LaBranche, C.C.1
Hoffman, T.L.2
Romano, J.3
-
51
-
-
16144365390
-
CD4-independent infection by HIV-2 is mediated by fusin/CXCR4
-
Endres MJ, Clapham PR, Marsh M, et al. CD4-independent infection by HIV-2 is mediated by fusin/CXCR4. Cell 1996; 87 (4): 745-56
-
(1996)
Cell
, vol.87
, Issue.4
, pp. 745-756
-
-
Endres, M.J.1
Clapham, P.R.2
Marsh, M.3
-
52
-
-
0030949336
-
CD4-independent infection by HIV-2 (ROD/B): Use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry
-
Reeves JD, McKnight A, Potempa S, et al. CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry. Virology 1997; 231 (1): 130-4
-
(1997)
Virology
, vol.231
, Issue.1
, pp. 130-134
-
-
Reeves, J.D.1
McKnight, A.2
Potempa, S.3
-
53
-
-
2542499674
-
CD4-independent infection of HIV and SIV: Implications for envelope conformation and cell tropism in vivo
-
Bhattacharya J, Peters PJ, Clapham PR. CD4-independent infection of HIV and SIV: implications for envelope conformation and cell tropism in vivo. AIDS 2003; 17 Suppl. 4: S35-43
-
(2003)
AIDS
, vol.17
, Issue.4 SUPPL.
-
-
Bhattacharya, J.1
Peters, P.J.2
Clapham, P.R.3
-
54
-
-
0036268538
-
Human immunodeficiency virus type 2
-
Reeves JD, Doms RW. Human immunodeficiency virus type 2. J Gen Virol 2002; 83 (Pt 6): 1253-65
-
(2002)
J Gen Virol
, vol.83
, Issue.6 PART
, pp. 1253-1265
-
-
Reeves, J.D.1
Doms, R.W.2
-
55
-
-
0032856713
-
Primary human immuimmunodeficiency virus type 2 (HIV-2) isolates infect CD4-negative cells via CCR5 and CXCR4: Comparison with HIV-1 and simian immunodeficiency virus and relevance to cell tropism in vivo
-
Reeves JD, Hibbitts S, Simmons G, et al. Primary human immuimmunodeficiency virus type 2 (HIV-2) isolates infect CD4-negative cells via CCR5 and CXCR4: comparison with HIV-1 and simian immunodeficiency virus and relevance to cell tropism in vivo. J Virol 1999; 73 (9): 7795-804
-
(1999)
J Virol
, vol.73
, Issue.9
, pp. 7795-7804
-
-
Reeves, J.D.1
Hibbitts, S.2
Simmons, G.3
-
56
-
-
0035035296
-
Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein
-
Edwards TG, Hoffman TL, Baribaud F, et al. Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein. J Virol 2001; 75 (11): 5230-9
-
(2001)
J Virol
, vol.75
, Issue.11
, pp. 5230-5239
-
-
Edwards, T.G.1
Hoffman, T.L.2
Baribaud, F.3
-
57
-
-
0032990223
-
Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein
-
Hoffman TL, LaBranche CC, Zhang W, et al. Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proc Natl Acad Sci U S A 1999; 96 (11): 6359-64
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.11
, pp. 6359-6364
-
-
Hoffman, T.L.1
LaBranche, C.C.2
Zhang, W.3
-
58
-
-
0037220770
-
The anti-HIV potency of cyclotriazadisulfonamide analogs is directly correlated with their ability to down-modulate the CD4 receptor
-
Vermeire K, Bell TW, Choi HJ, et al. The anti-HIV potency of cyclotriazadisulfonamide analogs is directly correlated with their ability to down-modulate the CD4 receptor. Mol Pharmacol 2003; 63 (1): 203-10
-
(2003)
Mol Pharmacol
, vol.63
, Issue.1
, pp. 203-210
-
-
Vermeire, K.1
Bell, T.W.2
Choi, H.J.3
-
59
-
-
0036436747
-
CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor
-
Vermeire K, Zhang Y, Princen K, et al. CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor. Virology 2002; 302 (2): 342-53
-
(2002)
Virology
, vol.302
, Issue.2
, pp. 342-353
-
-
Vermeire, K.1
Zhang, Y.2
Princen, K.3
-
60
-
-
0347320929
-
Specific CD4 down-modulating compounds with potent anti-HIV activity
-
Vermeire K, Schols D. Specific CD4 down-modulating compounds with potent anti-HIV activity. J Leukoc Biol 2003; 74 (5): 667-75
-
(2003)
J Leukoc Biol
, vol.74
, Issue.5
, pp. 667-675
-
-
Vermeire, K.1
Schols, D.2
-
61
-
-
2442618847
-
CD4 down-modulating compounds with potent anti-HIV activity
-
Vermeire K, Schols D, Bell TW. CD4 down-modulating compounds with potent anti-HIV activity. Curr Pharm Des 2004; 10 (15): 1795-803
-
(2004)
Curr Pharm des
, vol.10
, Issue.15
, pp. 1795-1803
-
-
Vermeire, K.1
Schols, D.2
Bell, T.W.3
-
62
-
-
13344262687
-
Naphthalene sulfonate polymers with CD4-blocking and anti-human immunodeficiency virus type 1 activities
-
Rusconi S, Moonis M, Merrill DP, et al. Naphthalene sulfonate polymers with CD4-blocking and anti-human immunodeficiency virus type 1 activities. Antimicrob Agents Chemother 1996; 40 (1): 234-6
-
(1996)
Antimicrob Agents Chemother
, vol.40
, Issue.1
, pp. 234-236
-
-
Rusconi, S.1
Moonis, M.2
Merrill, D.P.3
-
63
-
-
0030788879
-
A humanized form of a CD4-specific monoclonal antibody exhibits decreased antigenicity and prolonged plasma half-life in rhesus monkeys while retaining its unique biological and antiviral properties
-
Reimann KA, Lin W, Bixler S, et al. A humanized form of a CD4-specific monoclonal antibody exhibits decreased antigenicity and prolonged plasma half-life in rhesus monkeys while retaining its unique biological and antiviral properties. AIDS Res Hum Retroviruses 1997; 13 (11): 933-43
-
(1997)
AIDS Res Hum Retroviruses
, vol.13
, Issue.11
, pp. 933-943
-
-
Reimann, K.A.1
Lin, W.2
Bixler, S.3
-
64
-
-
0026709705
-
Inhibition of HIV infection by a novel CD4 domain 2-specific monoclonal antibody: Dissecting the basis for its inhibitory effect on HIV-induced cell fusion
-
Burkly LC, Olson D, Shapiro R, et al. Inhibition of HIV infection by a novel CD4 domain 2-specific monoclonal antibody: dissecting the basis for its inhibitory effect on HIV-induced cell fusion. J Immunol 1992; 149 (5): 1779-87
-
(1992)
J Immunol
, vol.149
, Issue.5
, pp. 1779-1787
-
-
Burkly, L.C.1
Olson, D.2
Shapiro, R.3
-
65
-
-
0026654557
-
A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells
-
Moore JP, Sattentau QJ, Klasse PJ, et al. A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells. J Virol 1992; 66 (8): 4784-93
-
(1992)
J Virol
, vol.66
, Issue.8
, pp. 4784-4793
-
-
Moore, J.P.1
Sattentau, Q.J.2
Klasse, P.J.3
-
66
-
-
9144236197
-
Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1
-
Kuritzkes DR, Jacobson J, Powderly WG, et al. Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1. J Infect Dis 2004; 189 (2): 286-91
-
(2004)
J Infect Dis
, vol.189
, Issue.2
, pp. 286-291
-
-
Kuritzkes, D.R.1
Jacobson, J.2
Powderly, W.G.3
-
67
-
-
0029062687
-
Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates
-
Allaway GP, Davis-Bruno KL, Beaudry GA, et al. Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates. AIDS Res Hum Retroviruses 1995; 11 (5): 533-9
-
(1995)
AIDS Res Hum Retroviruses
, vol.11
, Issue.5
, pp. 533-539
-
-
Allaway, G.P.1
Davis-Bruno, K.L.2
Beaudry, G.A.3
-
68
-
-
0028865465
-
Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG
-
Trkola A, Pomales AB, Yuan H, et al. Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG. J Virol 1995; 69 (11): 6609-17
-
(1995)
J Virol
, vol.69
, Issue.11
, pp. 6609-6617
-
-
Trkola, A.1
Pomales, A.B.2
Yuan, H.3
-
69
-
-
9144250171
-
Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO 542
-
Jacobson JM, Israel RJ, Lowy I, et al. Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO 542. Antimicrob Agents Chemother 2004; 48 (2): 423-9
-
(2004)
Antimicrob Agents Chemother
, vol.48
, Issue.2
, pp. 423-429
-
-
Jacobson, J.M.1
Israel, R.J.2
Lowy, I.3
-
70
-
-
0033914939
-
Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults
-
Jacobson JM, Lowy I, Fletcher CV, et al. Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults. J Infect Dis 2000; 182 (1): 326-9
-
(2000)
J Infect Dis
, vol.182
, Issue.1
, pp. 326-329
-
-
Jacobson, J.M.1
Lowy, I.2
Fletcher, C.V.3
-
71
-
-
0033712475
-
Recombinant CD4-IgG2 in human immunodeficiency virus type 1-infected children: Phase 1/2 study
-
The Pediatric AIDS Clinical Trials Group Protocol 351 Study Team
-
Shearer WT, Israel RJ, Starr S, et al. Recombinant CD4-IgG2 in human immunodeficiency virus type 1-infected children: phase 1/2 study. The Pediatric AIDS Clinical Trials Group Protocol 351 Study Team. J Infect Dis 2000; 182 (6): 1774-9
-
(2000)
J Infect Dis
, vol.182
, Issue.6
, pp. 1774-1779
-
-
Shearer, W.T.1
Israel, R.J.2
Starr, S.3
-
72
-
-
0141856289
-
Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions
-
Guo Q, Ho HT, Dicker I, et al. Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions. J Virol 2003; 77 (19): 10528-36
-
(2003)
J Virol
, vol.77
, Issue.19
, pp. 10528-10536
-
-
Guo, Q.1
Ho, H.T.2
Dicker, I.3
-
73
-
-
0141703204
-
A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding
-
Lin PF, Blair W, Wang T, et al. A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding. Proc Natl Acad Sci U S A 2003; 100 (19): 11013-8
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.19
, pp. 11013-11018
-
-
Lin, P.F.1
Blair, W.2
Wang, T.3
-
74
-
-
1842562351
-
Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155
-
Madani N, Perdigoto AL, Srinivasan K, et al. Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155. J Virol 2004; 78 (7): 3742-52
-
(2004)
J Virol
, vol.78
, Issue.7
, pp. 3742-3752
-
-
Madani, N.1
Perdigoto, A.L.2
Srinivasan, K.3
-
75
-
-
11144358392
-
Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins
-
Si Z, Madani N, Cox JM, et al. Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins. Proc Natl Acad Sci U S A 2004; 101 (14): 5036-41
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.14
, pp. 5036-5041
-
-
Si, Z.1
Madani, N.2
Cox, J.M.3
-
77
-
-
16044367526
-
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
-
Huang Y, Paxton WA, Wolinsky SM, et al. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 1996; 2 (11): 1240-3
-
(1996)
Nat Med
, vol.2
, Issue.11
, pp. 1240-1243
-
-
Huang, Y.1
Paxton, W.A.2
Wolinsky, S.M.3
-
78
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
Samson M, Libert F, Doranz BJ, et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996; 382 (6593): 722-5
-
(1996)
Nature
, vol.382
, Issue.6593
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
-
79
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
Liu R, Paxton WA, Choe S, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996; 86 (3): 367-77
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
-
80
-
-
0001633495
-
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene: Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
-
Dean M, Carrington M, Winkler C, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene: Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 1996; 273 (5283): 1856-62
-
(1996)
Science
, vol.273
, Issue.5283
, pp. 1856-1862
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
-
81
-
-
0031575431
-
Change in coreceptor use coreceptor use correlates with disease progression in HIV-1 infected individuals
-
Connor RI, Sheridan KE, Ceradini D, et al. Change in coreceptor use coreceptor use correlates with disease progression in HIV-1 infected individuals. J Exp Med 1997; 185 (4): 621-8
-
(1997)
J Exp Med
, vol.185
, Issue.4
, pp. 621-628
-
-
Connor, R.I.1
Sheridan, K.E.2
Ceradini, D.3
-
82
-
-
14844333093
-
Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection
-
Moyle GJ, Wildfire A, Mandalia S, et al. Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection. J Infect Dis 2005; 191 (6): 866-72
-
(2005)
J Infect Dis
, vol.191
, Issue.6
, pp. 866-872
-
-
Moyle, G.J.1
Wildfire, A.2
Mandalia, S.3
-
83
-
-
0030002637
-
HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
-
Feng Y, Broder CC, Kennedy PE, et al. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996; 272 (5263): 872-7
-
(1996)
Science
, vol.272
, Issue.5263
, pp. 872-877
-
-
Feng, Y.1
Broder, C.C.2
Kennedy, P.E.3
-
84
-
-
15844389650
-
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
-
Dragic T, Litwin V, Allaway GP, et al. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 1996; 381: 667-73
-
(1996)
Nature
, vol.381
, pp. 667-673
-
-
Dragic, T.1
Litwin, V.2
Allaway, G.P.3
-
85
-
-
0030604727
-
A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
-
Doranz BJ, Rucker J, Yi Y, et al. A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 1996; 85 (7): 1149-58
-
(1996)
Cell
, vol.85
, Issue.7
, pp. 1149-1158
-
-
Doranz, B.J.1
Rucker, J.2
Yi, Y.3
-
86
-
-
0030018156
-
CC CKR5: A RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1
-
Alkhatib G, Combadiere C, Broder CC, et al. CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 1996; 272 (5270): 1955-8
-
(1996)
Science
, vol.272
, Issue.5270
, pp. 1955-1958
-
-
Alkhatib, G.1
Combadiere, C.2
Broder, C.C.3
-
87
-
-
16144365317
-
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
-
Trkola A, Dragic T, Arthos J, et al. CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature 1996; 384: 184-7
-
(1996)
Nature
, vol.384
, pp. 184-187
-
-
Trkola, A.1
Dragic, T.2
Arthos, J.3
-
88
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
Deng H, Liu R, Ellmeier W, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996; 381 (6584): 661-6
-
(1996)
Nature
, vol.381
, Issue.6584
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
-
89
-
-
0005014748
-
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
-
Choe H, Farzan M, Sun Y, et al. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 1996; 85 (7): 1135-48
-
(1996)
Cell
, vol.85
, Issue.7
, pp. 1135-1148
-
-
Choe, H.1
Farzan, M.2
Sun, Y.3
-
90
-
-
16144365650
-
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
-
Wu L, Gerard NP, Wyatt R, et al. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature 1996; 384: 179-83
-
(1996)
Nature
, vol.384
, pp. 179-183
-
-
Wu, L.1
Gerard, N.P.2
Wyatt, R.3
-
91
-
-
0029417004
-
Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells
-
Cocchi F, DeVico AL, Garzino-Demo A, et al. Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science 1995; 270 (5243): 1811-5
-
(1995)
Science
, vol.270
, Issue.5243
, pp. 1811-1815
-
-
Cocchi, F.1
DeVico, A.L.2
Garzino-Demo, A.3
-
92
-
-
12644274812
-
Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure
-
Paxton WA, Martin SR, Tse D, et al. Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure. Nat Med 1996; 2 (4): 412-7
-
(1996)
Nat Med
, vol.2
, Issue.4
, pp. 412-417
-
-
Paxton, W.A.1
Martin, S.R.2
Tse, D.3
-
93
-
-
0029775576
-
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
-
Bleul CC, Farzan M, Choe H, et al. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996; 382 (6594): 829-33
-
(1996)
Nature
, vol.382
, Issue.6594
, pp. 829-833
-
-
Bleul, C.C.1
Farzan, M.2
Choe, H.3
-
94
-
-
16044370087
-
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
-
Oberlin E, Amara A, Bachelerie F, et al. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 1996; 382 (6594): 833-5
-
(1996)
Nature
, vol.382
, Issue.6594
, pp. 833-835
-
-
Oberlin, E.1
Amara, A.2
Bachelerie, F.3
-
95
-
-
0032550337
-
Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity
-
Mack M, Luckow B, Nelson PJ, et al. Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity. J Exp Med 1998; 187 (8): 1215-24
-
(1998)
J Exp Med
, vol.187
, Issue.8
, pp. 1215-1224
-
-
Mack, M.1
Luckow, B.2
Nelson, P.J.3
-
96
-
-
0030951442
-
Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist
-
Simmons G, Clapham PR, Picard L, et al. Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist. Science 1997; 276 (5310): 276-9
-
(1997)
Science
, vol.276
, Issue.5310
, pp. 276-279
-
-
Simmons, G.1
Clapham, P.R.2
Picard, L.3
-
97
-
-
3042780489
-
Co-receptor antagonists as HIV-1 entry inhibitors
-
Shaheen F, Collman RG. Co-receptor antagonists as HIV-1 entry inhibitors. Curr Opin Infect Dis 2004; 17 (1): 7-16
-
(2004)
Curr Opin Infect Dis
, vol.17
, Issue.1
, pp. 7-16
-
-
Shaheen, F.1
Collman, R.G.2
-
98
-
-
0037872129
-
Recent progress in discovery of small-molecule CCR5 chemokine receptor ligands as HIV-1 inhibitors
-
Kazmierski W, Bifulco N, Yang H, et al. Recent progress in discovery of small-molecule CCR5 chemokine receptor ligands as HIV-1 inhibitors. Bioorg Med Chem 2003; 11 (13): 2663-76
-
(2003)
Bioorg Med Chem
, vol.11
, Issue.13
, pp. 2663-2676
-
-
Kazmierski, W.1
Bifulco, N.2
Yang, H.3
-
99
-
-
13044256383
-
A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
-
Baba M, Nishimura O, Kanzaki N, et al. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proc Natl Acad Sci U S A 1999; 96 (10): 5698-703
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.10
, pp. 5698-5703
-
-
Baba, M.1
Nishimura, O.2
Kanzaki, N.3
-
100
-
-
0034625144
-
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
-
Dragic T, Trkola A, Thompson DA, et al. A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5. Proc Natl Acad Sci U S A 2000; 97 (10): 5639-44
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.10
, pp. 5639-5644
-
-
Dragic, T.1
Trkola, A.2
Thompson, D.A.3
-
101
-
-
0037404511
-
Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry
-
Tsamis F, Gavrilov S, Kajumo F, et al. Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry. J Virol 2003; 77 (9): 5201-8
-
(2003)
J Virol
, vol.77
, Issue.9
, pp. 5201-5208
-
-
Tsamis, F.1
Gavrilov, S.2
Kajumo, F.3
-
102
-
-
0035940445
-
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo
-
Strizki JM, Xu S, Wagner NE, et al. SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo. Proc Natl Acad Sci U S A 2001; 98 (22): 12718-23
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.22
, pp. 12718-12723
-
-
Strizki, J.M.1
Xu, S.2
Wagner, N.E.3
-
103
-
-
0036232981
-
Anti-human immunodeficiency virus interactions of SCH-C (SCH 351125), a CCR5 Antagonist, with other antiretroviral agents in vitro
-
Tremblay CL, Giguel F, Kollmann C, et al. Anti-human immunodeficiency virus interactions of SCH-C (SCH 351125), a CCR5 Antagonist, with other antiretroviral agents in vitro. Antimicrob Agents Chemother 2002; 46 (5): 1336-9
-
(2002)
Antimicrob Agents Chemother
, vol.46
, Issue.5
, pp. 1336-1339
-
-
Tremblay, C.L.1
Giguel, F.2
Kollmann, C.3
-
106
-
-
2342544143
-
Piperazine-based CCR5 antagonists as HIV-1 inhibitors: IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[4-[2-methoxy-1 (R)-4- (trifluoromethyl)phenyl]ethyl-3 (S)-methyl-1-piperazinyl]-4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist
-
Tagat JR, McCombie SW, Nazareno D, et al. Piperazine-based CCR5 antagonists as HIV-1 inhibitors: IV. Discovery of 1-[(4,6-dimethyl-5- pyrimidinyl)carbonyl]-4-[4-[2-methoxy-1 (R)-4-(trifluoromethyl)phenyl]ethyl-3 (S)-methyl-1-piperazinyl]-4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. J Med Chem 2004; 47 (10): 2405-8
-
(2004)
J Med Chem
, vol.47
, Issue.10
, pp. 2405-2408
-
-
Tagat, J.R.1
McCombie, S.W.2
Nazareno, D.3
-
107
-
-
3543144738
-
Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro
-
Maeda K, Nakata H, Koh Y, et al. Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro. J Virol 2004; 78 (16): 8654-62
-
(2004)
J Virol
, vol.78
, Issue.16
, pp. 8654-8662
-
-
Maeda, K.1
Nakata, H.2
Koh, Y.3
-
108
-
-
14944366520
-
873140, a novel CCR5 antagonist: Antiviral activity and safety during short-term monotherapy in HIV-infected adults
-
abstract no. 114. Oct 30-Nov 2; Washington, DC
-
Lalezari J, Thompson M, Kumar P, et al. 873140, a novel CCR5 antagonist: antiviral activity and safety during short-term monotherapy in HIV-infected adults [abstract no. 114]. 44th ICAAC; 2004 Oct 30-Nov 2; Washington, DC
-
(2004)
44th ICAAC
-
-
Lalezari, J.1
Thompson, M.2
Kumar, P.3
-
109
-
-
0042896003
-
UK-427,857, a novel small molecule HIV entry inhibitor is a specific antagonist of the chemokine receptor CCR5
-
abstract no. 12. Feb 10-14; Boston (MA)
-
Dorr P, Macartney M, Rickett G, et al. UK-427,857, a novel small molecule HIV entry inhibitor is a specific antagonist of the chemokine receptor CCR5 [abstract no. 12]. 10th Conference on Retroviruses and Opportunistic Infections; 2003 Feb 10-14; Boston (MA)
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Dorr, P.1
Macartney, M.2
Rickett, G.3
-
110
-
-
24344447035
-
In vitro escape of R5 primary isolates from the CCR5 antagonist, UK-427,857, is difficult and involves continued use of the CCR5 receptor
-
Westby M, Smith-Burchnell C, Mori J, et al. In vitro escape of R5 primary isolates from the CCR5 antagonist, UK-427,857, is difficult and involves continued use of the CCR5 receptor [abstract]. Antivir Ther 2004; 9 (4): S10
-
(2004)
Antivir Ther
, vol.9
, Issue.4
-
-
Westby, M.1
Smith-Burchnell, C.2
Mori, J.3
-
112
-
-
0032924183
-
Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants
-
Mosier DE, Picchio GR, Gulizia RJ, et al. Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants. J Virol 1999; 73 (5): 3544-50
-
(1999)
J Virol
, vol.73
, Issue.5
, pp. 3544-3550
-
-
Mosier, D.E.1
Picchio, G.R.2
Gulizia, R.J.3
-
113
-
-
12144289333
-
Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule CCR5 inhibitor
-
Kuhmann SE, Pugach P, Kunstman KJ, et al. Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule CCR5 inhibitor. J Virol 2004; 78 (6): 2790-807
-
(2004)
J Virol
, vol.78
, Issue.6
, pp. 2790-2807
-
-
Kuhmann, S.E.1
Pugach, P.2
Kunstman, K.J.3
-
114
-
-
0037039380
-
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not inimplication volve CXCR4 use
-
Trkola A, Kuhmann SE, Strizki JM, et al. HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not inimplication volve CXCR4 use. Proc Natl Acad Sci U S A 2002; 99 (1): 395-400
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.1
, pp. 395-400
-
-
Trkola, A.1
Kuhmann, S.E.2
Strizki, J.M.3
-
115
-
-
4544299731
-
Effect of a CCR5 inhibitor on viral loads in macaques dual-infected with R5 and X4 primate immunodeficiency viruses
-
Wolinsky SM, Veazey RS, Kunstman KJ, et al. Effect of a CCR5 inhibitor on viral loads in macaques dual-infected with R5 and X4 primate immunodeficiency viruses. Virology 2004; 328 (1): 19-29
-
(2004)
Virology
, vol.328
, Issue.1
, pp. 19-29
-
-
Wolinsky, S.M.1
Veazey, R.S.2
Kunstman, K.J.3
-
116
-
-
3543142878
-
Predominance of CXCR4 utilising variants in a non-responsive dual tropic patient receiving the CCR5 antagonist UK-427,857
-
abstract no. 538. Feb 8-11; San Francisco (CA)
-
Westby M, Whitcomb J, Huang W, et al. Predominance of CXCR4 utilising variants in a non-responsive dual tropic patient receiving the CCR5 antagonist UK-427,857 [abstract no. 538]. 11th Conference on Retroviruses and Opportunistic Intion fections; 2004 Feb 8-11; San Francisco (CA)
-
(2004)
11th Conference on Retroviruses and Opportunistic Intion Fections
-
-
Westby, M.1
Whitcomb, J.2
Huang, W.3
-
117
-
-
2942555662
-
HIV co-receptors as targets for antiviral therapy
-
Schols D. HIV co-receptors as targets for antiviral therapy. Curr Top Med Chem 2004; 4 (9): 883-93
-
(2004)
Curr Top Med Chem
, vol.4
, Issue.9
, pp. 883-893
-
-
Schols, D.1
-
118
-
-
0032508033
-
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract
-
Tachibana K, Hirota S, Iizasa H, et al. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 1998; 393 (6685): 591-4
-
(1998)
Nature
, vol.393
, Issue.6685
, pp. 591-594
-
-
Tachibana, K.1
Hirota, S.2
Iizasa, H.3
-
119
-
-
0032507962
-
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
-
Zou YR, Kottmann AH, Kuroda M, et al. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 1998; 393 (6685): 595-9
-
(1998)
Nature
, vol.393
, Issue.6685
, pp. 595-599
-
-
Zou, Y.R.1
Kottmann, A.H.2
Kuroda, M.3
-
120
-
-
0038681342
-
The bicyclam AMD3100 story
-
De Clercq E. The bicyclam AMD3100 story. Nat Rev Drug Discov 2003; 2 (7): 581-7
-
(2003)
Nat Rev Drug Discov
, vol.2
, Issue.7
, pp. 581-587
-
-
De Clercq, E.1
-
121
-
-
0028209166
-
Highly potent and elective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100
-
De Clercq E, Yamamoto N, Pauwels R, et al. Highly potent and elective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100. Antimicrob Agents Chemother 1994; 38 (4): 668-74
-
(1994)
Antimicrob Agents Chemother
, vol.38
, Issue.4
, pp. 668-674
-
-
De Clercq, E.1
Yamamoto, N.2
Pauwels, R.3
-
122
-
-
0031891516
-
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
-
Donzella GA, Schols D, Lin SW, et al. AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor. Nat Med 1998; 4 (1): 72-7
-
(1998)
Nat Med
, vol.4
, Issue.1
, pp. 72-77
-
-
Donzella, G.A.1
Schols, D.2
Lin, S.W.3
-
123
-
-
0030830661
-
Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
-
Schols D, Struyf S, Van Damme J, et al. Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4. J Exp Med 1997; 186 (8): 1383-8
-
(1997)
J Exp Med
, vol.186
, Issue.8
, pp. 1383-1388
-
-
Schols, D.1
Struyf, S.2
Van Damme, J.3
-
124
-
-
0030835663
-
Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4
-
Schols D, Este JA, Henson G, et al. Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/ CXCR-4. Antiviral Res 1997; 35 (3): 147-56
-
(1997)
Antiviral Res
, vol.35
, Issue.3
, pp. 147-156
-
-
Schols, D.1
Este, J.A.2
Henson, G.3
-
125
-
-
0034120373
-
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCRantagonist: 4 Chemokine receptor, in human volunteers
-
Hendrix CW, Flexner C, MacFarland RT, et al. Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCRantagonist: 4 chemokine receptor, in human volunteers. Antimicrob Agents Chemother 2000; 44 (6): 1667-73
-
(2000)
Antimicrob Agents Chemother
, vol.44
, Issue.6
, pp. 1667-1673
-
-
Hendrix, C.W.1
Flexner, C.2
MacFarland, R.T.3
-
126
-
-
0011309256
-
AMD-3100, a CXCR4 antagonist, reduced HIV viral load and X4 virus levels in humans
-
abstract no. 2. Feb 24-28; Seattle (WA)
-
Schols D, Claes S, De Clercq E, et al. AMD-3100, a CXCR4 antagonist, reduced HIV viral load and X4 virus levels in humans [abstract no. 2]. 9th Conference on Retroviruses and Opportunistic Infections; 2002 Feb 24-28; Seattle (WA)
-
(2002)
9th Conference on Retroviruses and Opportunistic Infections
-
-
Schols, D.1
Claes, S.2
De Clercq, E.3
-
127
-
-
24344504623
-
Suppression of X4- and dual-tropic HIV-1 variants during a short course of monotherapy with the CXCR4 antagonist AMD 3100
-
Fransen S, Huang W, Toma J, et al. Suppression of X4- and dual-tropic HIV-1 variants during a short course of monotherapy with the CXCR4 antagonist AMD 3100 [abstract]. Antivir Ther 2004; 9: S11
-
(2004)
Antivir Ther
, vol.9
-
-
Fransen, S.1
Huang, W.2
Toma, J.3
-
128
-
-
0041893844
-
Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist H
-
abstract no. 563. Feb 10-14; Boston (MA)
-
Schols D, Claes S, Hatse S, et al. Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist H [abstract no. 563]. 10th Conference on Retroviruses and Opportunistic Infections; 2003 Feb 10-14; Boston (MA)
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Schols, D.1
Claes, S.2
Hatse, S.3
-
129
-
-
33747587175
-
Biologic activity of an orally bioavailable CXCR4 antagonist in human subjects
-
abstract no. TuPeB4475. Jul 11-16; Bangkok
-
Stone N, Dunaway S, Flexner C, et al. Biologic activity of an orally bioavailable CXCR4 antagonist in human subjects [abstract no. TuPeB4475]. XV International AIDS Conference; 2004 Jul 11-16; Bangkok
-
(2004)
XV International AIDS Conference
-
-
Stone, N.1
Dunaway, S.2
Flexner, C.3
-
131
-
-
0029072191
-
A molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: Inimplication for viral fusion
-
Chen CH, Matthews TJ, McDanal CB, et al. A molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: inimplication for viral fusion. J Virol 1995; 69 (6): 3771-7
-
(1995)
J Virol
, vol.69
, Issue.6
, pp. 3771-3777
-
-
Chen, C.H.1
Matthews, T.J.2
McDanal, C.B.3
-
132
-
-
0037301373
-
Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites
-
He Y, Vassell R, Zaitseva M, et al. Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites. J Virol 2003; 77 (3): 1666-71
-
(2003)
J Virol
, vol.77
, Issue.3
, pp. 1666-1671
-
-
He, Y.1
Vassell, R.2
Zaitseva, M.3
-
133
-
-
0035900003
-
HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process
-
Gallo SA, Puri A, Blumenthal R. HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process. Biochemistry 2001; 40 (41): 12231-6
-
(2001)
Biochemistry
, vol.40
, Issue.41
, pp. 12231-12236
-
-
Gallo, S.A.1
Puri, A.2
Blumenthal, R.3
-
134
-
-
2342466810
-
CD4-induced T-20 binding to human immunodeficiency virus type 1 gp120 blocks interaction with the CXCR4 coreceptor
-
Yuan W, Craig S, Si Z, et al. CD4-induced T-20 binding to human immunodeficiency virus type 1 gp120 blocks interaction with the CXCR4 coreceptor. J Virol 2004; 78 (10): 5448-57
-
(2004)
J Virol
, vol.78
, Issue.10
, pp. 5448-5457
-
-
Yuan, W.1
Craig, S.2
Si, Z.3
-
135
-
-
0038576281
-
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
-
Lalezari JP, Henry K, O'Hearn M, et al. Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. N Engl J Med 2003; 348 (22): 2175-85
-
(2003)
N Engl J Med
, vol.348
, Issue.22
, pp. 2175-2185
-
-
Lalezari, J.P.1
Henry, K.2
O'Hearn, M.3
-
136
-
-
0037849954
-
Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia
-
Lazzarin A, Clotet B, Cooper D, et al. Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia. N Engl J Med 2003; 348 (22): 2186-95
-
(2003)
N Engl J Med
, vol.348
, Issue.22
, pp. 2186-2195
-
-
Lazzarin, A.1
Clotet, B.2
Cooper, D.3
-
137
-
-
2942536481
-
HIV resistance to the fusion inhibitor enfuvirtide: Mechanisms and clinical implications
-
Miller MD, Hazuda DJ. HIV resistance to the fusion inhibitor enfuvirtide: mechanisms and clinical implications. Drug Resist Updat 2004; 7 (2): 89-95
-
(2004)
Drug Resist Updat
, vol.7
, Issue.2
, pp. 89-95
-
-
Miller, M.D.1
Hazuda, D.J.2
-
138
-
-
4444375658
-
Resistance to enfuvirtide, the first HIV fusion inhibitor
-
Aug
-
Greenberg ML, Cammack N. Resistance to enfuvirtide, the first HIV fusion inhibitor. J Antimicrob Chemother 2004 Aug; 54 (2): 333-40
-
(2004)
J Antimicrob Chemother
, vol.54
, Issue.2
, pp. 333-340
-
-
Greenberg, M.L.1
Cammack, N.2
-
139
-
-
0031883832
-
Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides
-
Rimsky LT, Shugars DC, Matthews TJ. Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides. J Virol 1998; 72 (2): 986-93
-
(1998)
J Virol
, vol.72
, Issue.2
, pp. 986-993
-
-
Rimsky, L.T.1
Shugars, D.C.2
Matthews, T.J.3
-
140
-
-
4544289304
-
Evolution of HR1 and HR2 mutations in HIV-1 gp41 associated with long-term enfuviragainst tide therapy
-
abstract no. 659. Feb 8-11; San Francisco (CA)
-
Xu L, Pozniak A, Wildfire A, et al. Evolution of HR1 and HR2 mutations in HIV-1 gp41 associated with long-term enfuviragainst tide therapy [abstract no. 659]. 11th Conference on Retroviruses and Opportunistic Infections; 2004 Feb 8-11; San Francisco (CA)
-
(2004)
11th Conference on Retroviruses and Opportunistic Infections
-
-
Xu, L.1
Pozniak, A.2
Wildfire, A.3
-
141
-
-
7644236011
-
Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor
-
Baldwin CE, Sanders RW, Deng Y, et al. Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor. J Virol 2004; 78 (22): 12428-37
-
(2004)
J Virol
, vol.78
, Issue.22
, pp. 12428-12437
-
-
Baldwin, C.E.1
Sanders, R.W.2
Deng, Y.3
-
142
-
-
0037183892
-
Evolution of the gp41 env region in HIV-infected patients receiving T-20, a fusion inhibitor
-
Poveda E, Rodes B, Toro C, et al. Evolution of the gp41 env region in HIV-infected patients receiving T-20, a fusion inhibitor. AIDS 2002; 16 (14): 1959-61
-
(2002)
AIDS
, vol.16
, Issue.14
, pp. 1959-1961
-
-
Poveda, E.1
Rodes, B.2
Toro, C.3
-
143
-
-
4344685387
-
Genotype and phenotype patterns of human immunodeficiency virus type 1 resistance to enfuvirtide during long-term treatment
-
Menzo S, Castagna A, Monachetti A, et al. Genotype and phenotype patterns of human immunodeficiency virus type 1 resistance to enfuvirtide during long-term treatment. Antimicrob Agents Chemother 2004; 48 (9): 3253-9
-
(2004)
Antimicrob Agents Chemother
, vol.48
, Issue.9
, pp. 3253-3259
-
-
Menzo, S.1
Castagna, A.2
Monachetti, A.3
-
144
-
-
3042799046
-
Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20)
-
Lu J, Sista P, Giguel F, et al. Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20). J Virol 2004; 78 (9): 4628-37
-
(2004)
J Virol
, vol.78
, Issue.9
, pp. 4628-4637
-
-
Lu, J.1
Sista, P.2
Giguel, F.3
-
145
-
-
3042687460
-
Characterization of genotypic determinants in HR-1 and HR-2 gp41 domains in individuals with persistent HIV viraemia under T-20
-
Marcelin AG, Reynes J, Yerly S, et al. Characterization of genotypic determinants in HR-1 and HR-2 gp41 domains in individuals with persistent HIV viraemia under T-20. AIDS 2004; 18 (9): 1340-2
-
(2004)
AIDS
, vol.18
, Issue.9
, pp. 1340-1342
-
-
Marcelin, A.G.1
Reynes, J.2
Yerly, S.3
-
146
-
-
0037877472
-
In vitro antiviral activity of T-1249 a second generation fusion inhibitor
-
Greenberg ML, Davison D, Jin L, et al. In vitro antiviral activity of T-1249 a second generation fusion inhibitor [abstract]. Antivir Ther 2002; 7 Suppl. 1: S10
-
(2002)
Antivir Ther
, vol.7
, Issue.1 SUPPL.
-
-
Greenberg, M.L.1
Davison, D.2
Jin, L.3
-
147
-
-
0012819236
-
T-1249 demonstrates potent antiviral activity over 10 day dosing in most patients who have failed a regimen containing enfuvirtide (ENF): Planned interim analysis of T1249-102, a phase I/II study
-
abstract no. 14lb. Feb 10-14; Boston (MA)
-
Miralles GD, Lalezari JP, Bellos N, et al. T-1249 demonstrates potent antiviral activity over 10 day dosing in most patients who have failed a regimen containing enfuvirtide (ENF): planned interim analysis of T1249-102, a phase I/II study [abstract no. 14lb]. 10th Conference on Retroviruses and Opportunistic Infections; 2003 Feb 10-14; Boston (MA)
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Miralles, G.D.1
Lalezari, J.P.2
Bellos, N.3
-
148
-
-
0034298213
-
Strong in vitro synergy between the fusion inhibitor T-20 and the CXCR4 blocker AMD-3100
-
Tremblay CL, Kollmann C, Giguel F, et al. Strong in vitro synergy between the fusion inhibitor T-20 and the CXCR4 blocker AMD-3100. J Acquir Immune Defic Syndr 2000; 25 (2): 99-102
-
(2000)
J Acquir Immune Defic Syndr
, vol.25
, Issue.2
, pp. 99-102
-
-
Tremblay, C.L.1
Kollmann, C.2
Giguel, F.3
-
149
-
-
0035313589
-
Human immunodeficiency virus type 1 entry inhibitors PRO 542 and T-20 are potently synergistic in blocking virus-cell and cell-cell fusion
-
Nagashima KA, Thompson DA, Rosenfield SI, et al. Human immunodeficiency virus type 1 entry inhibitors PRO 542 and T-20 are potently synergistic in blocking virus-cell and cell-cell fusion. J Infect Dis 2001; 183 (7): 1121-5
-
(2001)
J Infect Dis
, vol.183
, Issue.7
, pp. 1121-1125
-
-
Nagashima, K.A.1
Thompson, D.A.2
Rosenfield, S.I.3
-
150
-
-
12144290487
-
Short-term safety and antiretroviral activity of T-1249, a second-generation fusion inhibitor of HIV
-
Eron JJ, Gulick RM, Bartlett JA, et al. Short-term safety and antiretroviral activity of T-1249, a second-generation fusion inhibitor of HIV. J Infect Dis 2004; 189 (6): 1075-83
-
(2004)
J Infect Dis
, vol.189
, Issue.6
, pp. 1075-1083
-
-
Eron, J.J.1
Gulick, R.M.2
Bartlett, J.A.3
-
151
-
-
2442625211
-
HIV-1 gp41 as a target for viral entry inhibition
-
Root MJ, Steger HK. HIV-1 gp41 as a target for viral entry inhibition. Curr Pharm Des 2004; 10 (15): 1805-25
-
(2004)
Curr Pharm des
, vol.10
, Issue.15
, pp. 1805-1825
-
-
Root, M.J.1
Steger, H.K.2
-
152
-
-
0346258300
-
Preventing HIV-1 sexual transmission: Not sexy enough science, or no benefit to the bottom line?
-
Moore JP, Shattock RJ. Preventing HIV-1 sexual transmission: not sexy enough science, or no benefit to the bottom line? J Antimicrob Chemother 2003; 52 (6): 890-2
-
(2003)
J Antimicrob Chemother
, vol.52
, Issue.6
, pp. 890-892
-
-
Moore, J.P.1
Shattock, R.J.2
-
153
-
-
1642634947
-
Microbicides: Aids to safer sex
-
Shattock R, Solomon S. Microbicides: aids to safer sex. Lancet 2004; 363 (9414): 1002-3
-
(2004)
Lancet
, vol.363
, Issue.9414
, pp. 1002-1003
-
-
Shattock, R.1
Solomon, S.2
-
154
-
-
2442461960
-
HIV transmission: Closing all the doors
-
Davis CW, Doms RW. HIV transmission: closing all the doors. J Exp Med 2004; 199 (8): 1037-40
-
(2004)
J Exp Med
, vol.199
, Issue.8
, pp. 1037-1040
-
-
Davis, C.W.1
Doms, R.W.2
-
155
-
-
2442428094
-
Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue
-
Hu Q, Frank I, Williams V, et al. Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue. J Exp Med 2004; 199 (8): 1065-75
-
(2004)
J Exp Med
, vol.199
, Issue.8
, pp. 1065-1075
-
-
Hu, Q.1
Frank, I.2
Williams, V.3
-
156
-
-
0042368611
-
Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89.6P in macaques
-
Tsai CC, Emau P, Jiang Y, et al. Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89.6P in macaques. AIDS Res Hum Retroviruses 2003; 19 (7): 535-41
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, Issue.7
, pp. 535-541
-
-
Tsai, C.C.1
Emau, P.2
Jiang, Y.3
-
157
-
-
0742272702
-
Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models
-
Tsai CC, Emau P, Jiang Y, et al. Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models. AIDS Res Hum Retroviruses 2004; 20 (1): 11-8
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, Issue.1
, pp. 11-18
-
-
Tsai, C.C.1
Emau, P.2
Jiang, Y.3
-
158
-
-
0035902942
-
'Chemical condoms' for the prevention of HIV infection: Evaluation of novel agents against SHIV (89.6PD) in vitro and in vivo
-
Weber J, Nunn A, O'Connor T, et al. 'Chemical condoms' for the prevention of HIV infection: evaluation of novel agents against SHIV (89.6PD) in vitro and in vivo. AIDS 2001; 15 (12): 1563-8
-
(2001)
AIDS
, vol.15
, Issue.12
, pp. 1563-1568
-
-
Weber, J.1
Nunn, A.2
O'Connor, T.3
-
159
-
-
0034059527
-
A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women
-
Van Damme L, Wright A, Depraetere K, et al. A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women. Sex Transm Infect 2000; 76 (2): 126-30
-
(2000)
Sex Transm Infect
, vol.76
, Issue.2
, pp. 126-130
-
-
Van Damme, L.1
Wright, A.2
Depraetere, K.3
-
160
-
-
0037436284
-
Safety and tolerability of vaginal PRO 2000 gel in sexually active HIV-uninfected and abstinent HIV-infected women
-
Mayer KH, Karim SA, Kelly C, et al. Safety and tolerability of vaginal PRO 2000 gel in sexually active HIV-uninfected and abstinent HIV-infected women. AIDS 2003; 17 (3): 321-9
-
(2003)
AIDS
, vol.17
, Issue.3
, pp. 321-329
-
-
Mayer, K.H.1
Karim, S.A.2
Kelly, C.3
-
161
-
-
5644247983
-
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
-
Lederman MM, Veazey RS, Offord R, et al. Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5. Science 2004; 306 (5695): 485-7
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 485-487
-
-
Lederman, M.M.1
Veazey, R.S.2
Offord, R.3
-
162
-
-
10744225125
-
Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection
-
Veazey RS, Klasse PJ, Ketas TJ, et al. Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection. J Exp Med 2003; 198 (10): 1551-62
-
(2003)
J Exp Med
, vol.198
, Issue.10
, pp. 1551-1562
-
-
Veazey, R.S.1
Klasse, P.J.2
Ketas, T.J.3
-
163
-
-
0027985431
-
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
-
Burton DR, Pyati J, Koduri R, et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 1994; 266 (5187): 1024-7
-
(1994)
Science
, vol.266
, Issue.5187
, pp. 1024-1027
-
-
Burton, D.R.1
Pyati, J.2
Koduri, R.3
-
164
-
-
0345471066
-
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
-
Veazey RS, Shattock RJ, Pope M, et al. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nat Med 2003; 9 (3): 343-6
-
(2003)
Nat Med
, vol.9
, Issue.3
, pp. 343-346
-
-
Veazey, R.S.1
Shattock, R.J.2
Pope, M.3
-
165
-
-
0032723359
-
Integrating DNA: Transposases and retroviral integrases
-
Haren L, Ton-Hoang B, Chandler M. Integrating DNA: transposases and retroviral integrases. Annu Rev Microbiol 1999; 53: 245-81
-
(1999)
Annu Rev Microbiol
, vol.53
, pp. 245-281
-
-
Haren, L.1
Ton-Hoang, B.2
Chandler, M.3
-
167
-
-
3543122311
-
Evidence that stable retroviral transduction and cell survival following DNA integration depend on components of the nonhomologous end joining repair pathway
-
Daniel R, Greger JG, Katz RA, et al. Evidence that stable retroviral transduction and cell survival following DNA integration depend on components of the nonhomologous end joining repair pathway. J Virol 2004; 78 (16): 8573-81
-
(2004)
J Virol
, vol.78
, Issue.16
, pp. 8573-8581
-
-
Daniel, R.1
Greger, J.G.2
Katz, R.A.3
-
168
-
-
0035876374
-
Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection
-
Li L, Olvera JM, Yoder KE, et al. Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection. EMBO J 2001; 20 (12): 3272-81
-
(2001)
EMBO J
, vol.20
, Issue.12
, pp. 3272-3281
-
-
Li, L.1
Olvera, J.M.2
Yoder, K.E.3
-
169
-
-
0025968854
-
Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex
-
Farnet CM, Haseltine WA. Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex. J Virol 1991; 65 (4): 1910-5
-
(1991)
J Virol
, vol.65
, Issue.4
, pp. 1910-1915
-
-
Farnet, C.M.1
Haseltine, W.A.2
-
170
-
-
0024654338
-
A nucleoprotein complex mediates the integration of retroviral DNA
-
Bowerman B, Brown PO, Bishop JM, et al. A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev 1989; 3 (4): 469-78
-
(1989)
Genes Dev
, vol.3
, Issue.4
, pp. 469-478
-
-
Bowerman, B.1
Brown, P.O.2
Bishop, J.M.3
-
171
-
-
0030972160
-
Human immunodeficiency virus type 1 preintegration complexes: Studies of organization and composition
-
Miller MD, Farnet CM, Bushman FD. Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition. J Virol 1997; 71 (7): 5382-90
-
(1997)
J Virol
, vol.71
, Issue.7
, pp. 5382-5390
-
-
Miller, M.D.1
Farnet, C.M.2
Bushman, F.D.3
-
172
-
-
0031004162
-
HIV-1 cDNA integration: Requirement of HMG I (Y) protein for function of preintegration complexes in vitro
-
Farnet CM, Bushman FD. HIV-1 cDNA integration: requirement of HMG I (Y) protein for function of preintegration complexes in vitro. Cell 1997; 88 (4): 483-92
-
(1997)
Cell
, vol.88
, Issue.4
, pp. 483-492
-
-
Farnet, C.M.1
Bushman, F.D.2
-
173
-
-
0344211405
-
The barrier-to-autointegration factor is a component of functional human immunodeficiency virus type 1 preintegration complexes
-
Lin CW, Engelman A. The barrier-to-autointegration factor is a component of functional human immunodeficiency virus type 1 preintegration complexes. J Virol 2003; 77 (8): 5030-6
-
(2003)
J Virol
, vol.77
, Issue.8
, pp. 5030-5036
-
-
Lin, C.W.1
Engelman, A.2
-
174
-
-
0033052713
-
HMG protein family members stimulate human immunodeficiency virus type 1 and avian sarcoma virus concerted DNA integration in vitro
-
Hindmarsh P, Ridky T, Reeves R, et al. HMG protein family members stimulate human immunodeficiency virus type 1 and avian sarcoma virus concerted DNA integration in vitro. J Virol 1999; 73 (4): 2994-3003
-
(1999)
J Virol
, vol.73
, Issue.4
, pp. 2994-3003
-
-
Hindmarsh, P.1
Ridky, T.2
Reeves, R.3
-
175
-
-
0032433829
-
The barrier-to-autointegration protein is a host factor for HIV type 1 integration
-
Chen H, Engelman A. The barrier-to-autointegration protein is a host factor for HIV type 1 integration. Proc Natl Acad Sci U S A 1998; 95 (26): 15270-4
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.26
, pp. 15270-15274
-
-
Chen, H.1
Engelman, A.2
-
176
-
-
0037076324
-
Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes
-
Grobler JA, Stillmock K, Hu B, et al. Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes. Proc Natl Acad Sci U S A 2002; 99 (10): 6661-6
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.10
, pp. 6661-6666
-
-
Grobler, J.A.1
Stillmock, K.2
Hu, B.3
-
177
-
-
3843108916
-
A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase
-
Hazuda DJ, Anthony NJ, Gomez RP, et al. A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase. Proc Natl Acad Sci U S A 2004; 101 (31): 11233-8
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.31
, pp. 11233-11238
-
-
Hazuda, D.J.1
Anthony, N.J.2
Gomez, R.P.3
-
178
-
-
3242769788
-
Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques
-
Hazuda DJ, Young SD, Guare JP, et al. Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques. Science 2004; 305 (5683): 528-32
-
(2004)
Science
, vol.305
, Issue.5683
, pp. 528-532
-
-
Hazuda, D.J.1
Young, S.D.2
Guare, J.P.3
-
179
-
-
0034723439
-
Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
-
Hazuda DJ, Felock P, Witmer M, et al. Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells. Science 2000; 287 (5453): 646-50
-
(2000)
Science
, vol.287
, Issue.5453
, pp. 646-650
-
-
Hazuda, D.J.1
Felock, P.2
Witmer, M.3
-
180
-
-
0035087062
-
Anti-human immunodeficiency virus activity of YK-FH312 (a betulinic acid derivative), a novel compound blocking viral maturation
-
Kanamoto T, Kashiwada Y, Kanbara K, et al. Anti-human immunodeficiency virus activity of YK-FH312 (a betulinic acid derivative), a novel compound blocking viral maturation. Antimicrob Agents Chemother 2001; 45 (4): 1225-30
-
(2001)
Antimicrob Agents Chemother
, vol.45
, Issue.4
, pp. 1225-1230
-
-
Kanamoto, T.1
Kashiwada, Y.2
Kanbara, K.3
-
181
-
-
0345686713
-
PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing
-
Li F, Goila-Gaur R, Salzwedel K, et al. PA-457: a potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing. Proc Natl Acad Sci U S A 2003; 100 (23): 13555-60
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.23
, pp. 13555-13560
-
-
Li, F.1
Goila-Gaur, R.2
Salzwedel, K.3
-
182
-
-
4344615371
-
The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3′,3′-dimethylsuccinyl}-betulinic acid
-
Zhou J, Chen CH, Aiken C. The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3′,3′-dimethylsuccinyl}-betulinic acid. Retrovirology 2004; 1 (1): 15
-
(2004)
Retrovirology
, vol.1
, Issue.1
, pp. 15
-
-
Zhou, J.1
Chen, C.H.2
Aiken, C.3
-
183
-
-
0036828096
-
Characterization of a putative alpha-helix across the capsid-SP1 boundary that is critical for the multimerization of human immunodeficiency virus type 1 gag
-
Liang C, Hu J, Russell RS, et al. Characterization of a putative alpha-helix across the capsid-SP1 boundary that is critical for the multimerization of human immunodeficiency virus type 1 gag. J Virol 2002; 76 (22): 11729-37
-
(2002)
J Virol
, vol.76
, Issue.22
, pp. 11729-11737
-
-
Liang, C.1
Hu, J.2
Russell, R.S.3
-
184
-
-
0032036690
-
Fv1, the mouse retrovirus resistance gene
-
Stoye JP. Fv1, the mouse retrovirus resistance gene. Rev Sci Tech 1998; 17 (1): 269-77
-
(1998)
Rev Sci Tech
, vol.17
, Issue.1
, pp. 269-277
-
-
Stoye, J.P.1
-
185
-
-
0030588980
-
Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance
-
Kozak CA, Chakraborti A. Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance. Virology 1996; 225 (2): 300-5
-
(1996)
Virology
, vol.225
, Issue.2
, pp. 300-305
-
-
Kozak, C.A.1
Chakraborti, A.2
-
186
-
-
0034710884
-
A conserved mechanism of retrovirus restriction in mammals
-
Towers G, Bock M, Martin S, et al. A conserved mechanism of retrovirus restriction in mammals. Proc Natl Acad Sci U S A 2000; 97 (22): 12295-9
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.22
, pp. 12295-12299
-
-
Towers, G.1
Bock, M.2
Martin, S.3
-
187
-
-
0029763293
-
Positional cloning of the mouse retrovirus restriction gene Fv1
-
Best S, Le Tissier P, Towers G, et al. Positional cloning of the mouse retrovirus restriction gene Fv1. Nature 1996; 382 (6594): 826-9
-
(1996)
Nature
, vol.382
, Issue.6594
, pp. 826-829
-
-
Best, S.1
Le Tissier, P.2
Towers, G.3
-
188
-
-
0038003686
-
Restriction factors: A defense against retroviral infection
-
Bieniasz PD. Restriction factors: a defense against retroviral infection. Trends Microbiol 2003; 11 (6): 286-91
-
(2003)
Trends Microbiol
, vol.11
, Issue.6
, pp. 286-291
-
-
Bieniasz, P.D.1
-
189
-
-
0037015007
-
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism
-
Cowan S, Hatziioannou T, Cunningham T, et al. Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism. Proc Natl Acad Sci U S A 2002; 99 (18): 11914-9
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.18
, pp. 11914-11919
-
-
Cowan, S.1
Hatziioannou, T.2
Cunningham, T.3
-
191
-
-
1542288934
-
The cytoplasmic homobody component TRIM5alpha restricts HIV-1 infection in Old World monkeys
-
Stremlau M, Owens CM, Perron MJ, et al. The cytoplasmic homobody component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004; 427 (6977): 848-53
-
(2004)
Nature
, vol.427
, Issue.6977
, pp. 848-853
-
-
Stremlau, M.1
Owens, C.M.2
Perron, M.J.3
-
192
-
-
1542378949
-
HIV: Replication trimmed back
-
Goff SP. HIV: replication trimmed back. Nature 2004; 427 (6977): 791-3
-
(2004)
Nature
, vol.427
, Issue.6977
, pp. 791-793
-
-
Goff, S.P.1
-
193
-
-
3242708385
-
Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha
-
Hatziioannou T, Perez-Caballero D, Yang A, et al. Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha. Proc Natl Acad Sci U S A 2004; 101 (29): 10774-9
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.29
, pp. 10774-10779
-
-
Hatziioannou, T.1
Perez-Caballero, D.2
Yang, A.3
-
194
-
-
3242720240
-
Trim5alpha protein restricts both HIV-1 and murine leukemia virus
-
Yap MW, Nisole S, Lynch C, et al. Trim5alpha protein restricts both HIV-1 and murine leukemia virus. Proc Natl Acad Sci U S A 2004; 101 (29): 10786-91
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.29
, pp. 10786-10791
-
-
Yap, M.W.1
Nisole, S.2
Lynch, C.3
-
195
-
-
3242670402
-
The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities
-
Keckesova Z, Ylinen LM, Towers GJ. The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities. Proc Natl Acad Sci U S A 2004; 101 (29): 10780-5
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.29
, pp. 10780-10785
-
-
Keckesova, Z.1
Ylinen, L.M.2
Towers, G.J.3
-
196
-
-
0023191658
-
The sor gene of HIV-1 is required for efficient virus transmission in vitro
-
Fisher AG, Ensoli B, Ivanoff L, et al. The sor gene of HIV-1 is required for efficient virus transmission in vitro. Science 1987; 237 (4817): 888-93
-
(1987)
Science
, vol.237
, Issue.4817
, pp. 888-893
-
-
Fisher, A.G.1
Ensoli, B.2
Ivanoff, L.3
-
197
-
-
0023267788
-
The HIV 'A' (sor) gene product is essential for virus infectivity
-
Strebel K, Daugherty D, Clouse K, et al. The HIV 'A' (sor) gene product is essential for virus infectivity. Nature 1987; 328 (6132): 728-30
-
(1987)
Nature
, vol.328
, Issue.6132
, pp. 728-730
-
-
Strebel, K.1
Daugherty, D.2
Clouse, K.3
-
198
-
-
0027179103
-
Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells
-
von Schwedler U, Song J, Aiken C, et al. Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells. J Virol 1993; 67 (8): 4945-55
-
(1993)
J Virol
, vol.67
, Issue.8
, pp. 4945-4955
-
-
Von Schwedler, U.1
Song, J.2
Aiken, C.3
-
199
-
-
0026649561
-
Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes
-
Gabuzda DH, Lawrence K, Langhoff E, et al. Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes. J Virol 1992; 66 (11): 6489-95
-
(1992)
J Virol
, vol.66
, Issue.11
, pp. 6489-6495
-
-
Gabuzda, D.H.1
Lawrence, K.2
Langhoff, E.3
-
200
-
-
0031788565
-
Evidence for a newly discovered cellular anti-HIV-1 phenotype
-
Simon JH, Gaddis NC, Fouchier RA, et al. Evidence for a newly discovered cellular anti-HIV-1 phenotype. Nat Med 1998; 4 (12): 1397-400
-
(1998)
Nat Med
, vol.4
, Issue.12
, pp. 1397-1400
-
-
Simon, J.H.1
Gaddis, N.C.2
Fouchier, R.A.3
-
201
-
-
0037043699
-
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
-
Sheehy AM, Gaddis NC, Choi JD, et al. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 2002; 418 (6898): 646-50
-
(2002)
Nature
, vol.418
, Issue.6898
, pp. 646-650
-
-
Sheehy, A.M.1
Gaddis, N.C.2
Choi, J.D.3
-
202
-
-
6344294123
-
Amino-terminal region of the human immunodeficiency virus type 1 nucleocapsid is required for human APOBEC3G packaging
-
Luo K, Liu B, Xiao Z, et al. Amino-terminal region of the human immunodeficiency virus type 1 nucleocapsid is required for human APOBEC3G packaging. J Virol 2004; 78 (21): 11841-52
-
(2004)
J Virol
, vol.78
, Issue.21
, pp. 11841-11852
-
-
Luo, K.1
Liu, B.2
Xiao, Z.3
-
203
-
-
5344222683
-
Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor
-
Schafer A, Bogerd HP, Cullen BR. Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor. Virology 2004; 328 (2): 163-8
-
(2004)
Virology
, vol.328
, Issue.2
, pp. 163-168
-
-
Schafer, A.1
Bogerd, H.P.2
Cullen, B.R.3
-
204
-
-
0038004471
-
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
-
Zhang H, Yang B, Pomerantz RJ, et al. The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. Nature 2003; 424 (6944): 94-8
-
(2003)
Nature
, vol.424
, Issue.6944
, pp. 94-98
-
-
Zhang, H.1
Yang, B.2
Pomerantz, R.J.3
-
205
-
-
0038681023
-
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts
-
Mangeat B, Turelli P, Caron G, et al. Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature 2003; 424 (6944): 99-103
-
(2003)
Nature
, vol.424
, Issue.6944
, pp. 99-103
-
-
Mangeat, B.1
Turelli, P.2
Caron, G.3
-
206
-
-
0038681901
-
DNA deamination mediates innate immunity to retroviral infection
-
Harris RS, Bishop KN, Sheehy AM, et al. DNA deamination mediates innate immunity to retroviral infection. Cell 2003; 113 (6): 803-9
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 803-809
-
-
Harris, R.S.1
Bishop, K.N.2
Sheehy, A.M.3
-
207
-
-
0038363470
-
Hypermutation of HIV-1 DNA in the absence of the Vif protein
-
Lecossier D, Bouchonnet F, Clavel F, et al. Hypermutation of HIV-1 DNA in the absence of the Vif protein. Science 2003; 300 (5622): 1112
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1112
-
-
Lecossier, D.1
Bouchonnet, F.2
Clavel, F.3
-
208
-
-
0344413641
-
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif
-
Sheehy AM, Gaddis NC, Malim MH. The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. Nat Med 2003; 9 (11): 1404-7
-
(2003)
Nat Med
, vol.9
, Issue.11
, pp. 1404-1407
-
-
Sheehy, A.M.1
Gaddis, N.C.2
Malim, M.H.3
-
209
-
-
0242578406
-
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex
-
Yu X, Yu Y, Liu B, et al. Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. Science 2003; 302 (5647): 1056-60
-
(2003)
Science
, vol.302
, Issue.5647
, pp. 1056-1060
-
-
Yu, X.1
Yu, Y.2
Liu, B.3
-
210
-
-
17944363138
-
Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding
-
Garrus JE, von Schwedler UK, Pornillos OW, et al. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell 2001; 107 (1): 55-65
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 55-65
-
-
Garrus, J.E.1
Von Schwedler, U.K.2
Pornillos, O.W.3
-
211
-
-
0034940214
-
Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55 (Gag)
-
VerPlank L, Bouamr F, LaGrassa TJ, et al. Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55 (Gag). Proc Natl Acad Sci U S A 2001; 98 (14): 7724-9
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.14
, pp. 7724-7729
-
-
VerPlank, L.1
Bouamr, F.2
LaGrassa, T.J.3
-
212
-
-
10744233294
-
The protein network of HIV budding
-
von Schwedler UK, Stuchell M, Muller B, et al. The protein network of HIV budding. Cell 2003; 114 (6): 701-13
-
(2003)
Cell
, vol.114
, Issue.6
, pp. 701-713
-
-
Von Schwedler, U.K.1
Stuchell, M.2
Muller, B.3
-
213
-
-
4143061605
-
The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding
-
Stuchell MD, Garrus JE, Muller B, et al. The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. J Biol Chem 2004; 279 (34): 36059-71
-
(2004)
J Biol Chem
, vol.279
, Issue.34
, pp. 36059-36071
-
-
Stuchell, M.D.1
Garrus, J.E.2
Muller, B.3
-
214
-
-
0141844660
-
AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding
-
Strack B, Calistri A, Craig S, et al. AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. Cell 2003; 114 (6): 689-99
-
(2003)
Cell
, vol.114
, Issue.6
, pp. 689-699
-
-
Strack, B.1
Calistri, A.2
Craig, S.3
-
215
-
-
0142123069
-
Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins
-
Martin-Serrano J, Yarovoy A, Perez-Caballero D, et al. Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. Proc Natl Acad Sci U S A 2003; 100 (21): 12414-9
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.21
, pp. 12414-12419
-
-
Martin-Serrano, J.1
Yarovoy, A.2
Perez-Caballero, D.3
-
216
-
-
0034700088
-
Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2
-
Schubert U, Ott DE, Chertova EN, et al. Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2. Proc Natl Acad Sci U S A 2000; 97 (24): 13057-62
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.24
, pp. 13057-13062
-
-
Schubert, U.1
Ott, D.E.2
Chertova, E.N.3
-
217
-
-
0031900144
-
Ubiquitin is covalently attached to the p6Gag proteins of human immunodeficiency virus type 1 and simian immunodeficiency virus and to the p12Gag protein of Moloney murine leukemia virus
-
Ott DE, Coren LV, Copeland TD, et al. Ubiquitin is covalently attached to the p6Gag proteins of human immunodeficiency virus type 1 and simian immunodeficiency virus and to the p12Gag protein of Moloney murine leukemia virus. J Virol 1998; 72 (4): 2962-8
-
(1998)
J Virol
, vol.72
, Issue.4
, pp. 2962-2968
-
-
Ott, D.E.1
Coren, L.V.2
Copeland, T.D.3
-
218
-
-
0041888375
-
Tsg101 control of human immunodeficiency virus type 1 Gag trafficking and release
-
Goff A, Ehrlich LS, Cohen SN, et al. Tsg101 control of human immunodeficiency virus type 1 Gag trafficking and release. J Virol 2003; 77 (17): 9173-82
-
(2003)
J Virol
, vol.77
, Issue.17
, pp. 9173-9182
-
-
Goff, A.1
Ehrlich, L.S.2
Cohen, S.N.3
-
219
-
-
0027306176
-
Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses
-
Gottlinger HG, Dorfman T, Cohen EA, et al. Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses. Proc Natl Acad Sci U S A 1993; 90 (15): 7381-5
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.15
, pp. 7381-7385
-
-
Gottlinger, H.G.1
Dorfman, T.2
Cohen, E.A.3
-
220
-
-
0028863722
-
Function of human immunodeficiency virus type 1 Vpu protein in various cell types
-
Sakai H, Tokunaga K, Kawamura M, et al. Function of human immunodeficiency virus type 1 Vpu protein in various cell types. J Gen Virol 1995; 76 (Pt 11): 2717-22
-
(1995)
J Gen Virol
, vol.76
, Issue.11 PART
, pp. 2717-2722
-
-
Sakai, H.1
Tokunaga, K.2
Kawamura, M.3
-
222
-
-
0344303622
-
Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production
-
Varthakavi V, Smith RM, Bour SP, et al. Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production. Proc Natl Acad Sci U S A 2003; 100 (25):15154-9
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.25
, pp. 15154-15159
-
-
Varthakavi, V.1
Smith, R.M.2
Bour, S.P.3
|