Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 25, 2002, Pages 16249-16254

  Reeves, Jacqueline D ^a   Gallo, Stephen A ^b   Ahmad, Navid ^a   Miamidian, John L ^a   Harvey, Phoebe E ^a   Sharron, Matthew ^a   Pöhlmann, Stefan ^a   Sfakianos, Jeffrey N ^c   Derdeyn, Cynthia A ^c   Blumenthal, Robert ^b   Hunter, Eric ^c   Doms, Robert W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; ENVELOPE PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; STRAIN DIFFERENCE; VIRUS CELL INTERACTION; VIRUS ENVELOPE;

3T3 CELLS; AMIDES; AMINO ACID SUBSTITUTION; ANIMALS; ANTI-HIV AGENTS; ANTIGENS, CD4; DRUG RESISTANCE, VIRAL; GENES, ENV; HELA CELLS; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; KINETICS; MEMBRANE FUSION; MICE; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; QUATERNARY AMMONIUM COMPOUNDS; RECEPTORS, CCR5; RECEPTORS, CXCR4; RECOMBINANT FUSION PROTEINS;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037059049     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.252469399     Document Type: Article

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