Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist

Science

Volumn 276, Issue 5310, 1997, Pages 276-279

  Simmons, Graham ^a   Clapham, Paul R ^a   Picard, Laurent ^a   Offord, Robin E ^b,c   Rosenkilde, Mette M ^d   Schwartz, Thue W ^d   Buser, Raphaële ^e   Wells, Timothy N C ^e   Proudfoot, Amanda E I ^e  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c Gryphon Therapeutics   (United States)

^d University of Copenhagen   (Denmark)

^e GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR; RANTES; RECEPTOR BLOCKING AGENT;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE; MACROPHAGE; PRIORITY JOURNAL; VIRUS INHIBITION; VIRUS VIRULENCE;

ANIMALS; ANTIGENS, CD4; BINDING, COMPETITIVE; CATS; CELL LINE; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; HELA CELLS; HIV-1; HUMANS; MACROPHAGE INFLAMMATORY PROTEIN-1; MACROPHAGES; RANTES; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; RECEPTORS, CYTOKINE; RECEPTORS, HIV; T-LYMPHOCYTES; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030951442     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.276.5310.276     Document Type: Article

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