-
1
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
-
Palella FJ, Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998; 338: 853-860.
-
(1998)
N Engl J Med
, vol.338
, pp. 853-860
-
-
Palella Jr., F.J.1
Delaney, K.M.2
Moorman, A.C.3
-
2
-
-
0033650238
-
Drug interactions of antiretroviral agents
-
Volberding PA, Jacobsen MA (eds). Marcel Dekker: New York
-
Kosel BW, Aweeka F. Drug interactions of antiretroviral agents. In AIDS Clinical Review, Volberding PA, Jacobsen MA (eds). Marcel Dekker: New York, 2003; 193-227.
-
(2003)
AIDS Clinical Review
, pp. 193-227
-
-
Kosel, B.W.1
Aweeka, F.2
-
3
-
-
0035922595
-
Prevalence of adverse events associated with potent antiretroviral treatment: Swiss HIV Cohort Study
-
Fellay J, Boubaker K, Ledergerber B, et al. Prevalence of adverse events associated with potent antiretroviral treatment: Swiss HIV Cohort Study. Lancet 2001; 358: 1322-1327.
-
(2001)
Lancet
, vol.358
, pp. 1322-1327
-
-
Fellay, J.1
Boubaker, K.2
Ledergerber, B.3
-
4
-
-
0037055025
-
Antiretroviral treatment for adult HIV infection in 2002: Updated recommendations of the International AIDS Society-USA Panel
-
Yeni PG, Hammer SM, Carpenter CC, et al. Antiretroviral treatment for adult HIV infection in 2002: updated recommendations of the International AIDS Society-USA Panel. JAMA 2002; 288: 222-235.
-
(2002)
JAMA
, vol.288
, pp. 222-235
-
-
Yeni, P.G.1
Hammer, S.M.2
Carpenter, C.C.3
-
5
-
-
0032103187
-
Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients
-
Shafer RW, Winters MA, Palmer S, et al. Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients. Ann Intern Med 1998; 128: 906-911.
-
(1998)
Ann Intern Med
, vol.128
, pp. 906-911
-
-
Shafer, R.W.1
Winters, M.A.2
Palmer, S.3
-
6
-
-
0036095978
-
HIV integrase as a target for antiviral chemotherapy
-
Nair V. HIV integrase as a target for antiviral chemotherapy. Rev Med Virol 2002; 12: 179-193.
-
(2002)
Rev Med Virol
, vol.12
, pp. 179-193
-
-
Nair, V.1
-
7
-
-
0031891516
-
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
-
Donzella GA, Schols D, Lin SW, et al. AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor. Nat Med 1998; 4: 72-77.
-
(1998)
Nat Med
, vol.4
, pp. 72-77
-
-
Donzella, G.A.1
Schols, D.2
Lin, S.W.3
-
8
-
-
0141856289
-
Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions
-
Guo Q, Ho HT, Dicker I, et al. Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions. J Virol 2003; 77: 10528-10536.
-
(2003)
J Virol
, vol.77
, pp. 10528-10536
-
-
Guo, Q.1
Ho, H.T.2
Dicker, I.3
-
9
-
-
0034120373
-
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
-
Hendrix CW, Flexner C, MacFarland RT, et al. Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers. Antimicrob Agents Chemother 2000; 44: 1667-1673.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1667-1673
-
-
Hendrix, C.W.1
Flexner, C.2
MacFarland, R.T.3
-
10
-
-
0033914939
-
Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults
-
Jacobson JM, Lowy I, Fletcher CV, et al. Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults. J Infect Dis 2000; 182: 326-329.
-
(2000)
J Infect Dis
, vol.182
, pp. 326-329
-
-
Jacobson, J.M.1
Lowy, I.2
Fletcher, C.V.3
-
11
-
-
0026598159
-
Mapping genetic determinants for human immunodeficiency virus type 1 resistance to soluble CD4
-
O'Brien WA, Chen IS, Ho DD, et al. Mapping genetic determinants for human immunodeficiency virus type 1 resistance to soluble CD4. J Virol 1992; 66: 3125-3130.
-
(1992)
J Virol
, vol.66
, pp. 3125-3130
-
-
O'Brien, W.A.1
Chen, I.S.2
Ho, D.D.3
-
12
-
-
0029029107
-
Phase I study of high-dose, intravenous rsCD4 in subjects with advanced HIV-1 infection
-
Schacker T, Collier AC, Coombs R, et al. Phase I study of high-dose, intravenous rsCD4 in subjects with advanced HIV-1 infection. J Acquir Immune Defic Syndr Hum Retrovirol 1995; 9: 145-152.
-
(1995)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.9
, pp. 145-152
-
-
Schacker, T.1
Collier, A.C.2
Coombs, R.3
-
13
-
-
0041893844
-
Anti-HIV activity of AMD070, an orally bioavailable CXCR4 antagonist H
-
Boston, USA, 10-14 February; Abstract 563
-
Schols D, Claes S, Hatse S, et al. Anti-HIV activity of AMD070, an orally bioavailable CXCR4 antagonist H. In 10th Conference on Retroviruses and Opportunistic Infections, Boston, USA, 10-14 February 2003; Abstract 563.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Schols, D.1
Claes, S.2
Hatse, S.3
-
14
-
-
0025093595
-
Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase I-II escalating dosage trial
-
Schooley RT, Merigan TC, Gaut P, et al. Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase I-II escalating dosage trial. Ann Intern Med 1990; 112: 247-253.
-
(1990)
Ann Intern Med
, vol.112
, pp. 247-253
-
-
Schooley, R.T.1
Merigan, T.C.2
Gaut, P.3
-
15
-
-
0035940445
-
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo
-
Strizki JM, Xu S, Wagner NE, et al. SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo. Proc Natl Acad Sci USA 2001; 98: 12718-12723.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12718-12723
-
-
Strizki, J.M.1
Xu, S.2
Wagner, N.E.3
-
16
-
-
0141680855
-
Discovery of 4-benzoyl-1-[(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl) oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): A novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions
-
Wang T, Zhang Z, Wallace OB, et al. Discovery of 4-benzoyl-1-[(4-methoxy- 1H-pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions. J Med Chem 2003; 46: 4236-4239.
-
(2003)
J Med Chem
, vol.46
, pp. 4236-4239
-
-
Wang, T.1
Zhang, Z.2
Wallace, O.B.3
-
17
-
-
0027959493
-
Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection
-
Wild CT, Shugars DC, Greenwell TK, et al. Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection. Proc Natl Acad Sci USA 1994; 91: 9770-9774.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9770-9774
-
-
Wild, C.T.1
Shugars, D.C.2
Greenwell, T.K.3
-
18
-
-
0025095635
-
Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein
-
Earl PL, Doms RW, Moss B. Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein. Proc Natl Acad Sci USA 1990; 87: 648-652.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 648-652
-
-
Earl, P.L.1
Doms, R.W.2
Moss, B.3
-
19
-
-
0027234624
-
Evidence that the structural conformation of envelope gp120 affects human immunodeficiency virus type 1 infectivity, host range, and syncytium-forming ability
-
Stamatatos L, Cheng-Mayer C. Evidence that the structural conformation of envelope gp120 affects human immunodeficiency virus type 1 infectivity, host range, and syncytium-forming ability. J Virol 1993; 67: 5635-5639.
-
(1993)
J Virol
, vol.67
, pp. 5635-5639
-
-
Stamatatos, L.1
Cheng-Mayer, C.2
-
20
-
-
0023669119
-
Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus
-
Gallaher WR. Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus. Cell 1987; 50: 327-328.
-
(1987)
Cell
, vol.50
, pp. 327-328
-
-
Gallaher, W.R.1
-
21
-
-
0024392364
-
A general model for the transmembrane proteins of HIV and other retroviruses
-
Gallaher WR, Ball JM, Carry RF, et al. A general model for the transmembrane proteins of HIV and other retroviruses. AIDS Res Hum Retroviruses 1989; 5: 431-440.
-
(1989)
AIDS Res Hum Retroviruses
, vol.5
, pp. 431-440
-
-
Gallaher, W.R.1
Ball, J.M.2
Carry, R.F.3
-
22
-
-
0025010813
-
Retroviral envelope glycoproteins contain a 'leucine zipper'-like repeat
-
Delwart EL, Mosialos G, Gilmore T. Retroviral envelope glycoproteins contain a 'leucine zipper'-like repeat. AIDS Res Hum Retroviruses 1990; 6: 703-706.
-
(1990)
AIDS Res Hum Retroviruses
, vol.6
, pp. 703-706
-
-
Delwart, E.L.1
Mosialos, G.2
Gilmore, T.3
-
23
-
-
0030962291
-
Atomic structure of the ectodomain from HIV-1 gp41
-
Weissenhorn W, Dessen A, Harrison SC, et al. Atomic structure of the ectodomain from HIV-1 gp41. Nature 1997; 387: 426-430.
-
(1997)
Nature
, vol.387
, pp. 426-430
-
-
Weissenhorn, W.1
Dessen, A.2
Harrison, S.C.3
-
24
-
-
0031902829
-
CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: Consequences for virus entry and neutralization
-
Sullivan N, Sun Y, Sattentau Q, et al. CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization. J Virol 1998; 72: 4694-4703.
-
(1998)
J Virol
, vol.72
, pp. 4694-4703
-
-
Sullivan, N.1
Sun, Y.2
Sattentau, Q.3
-
25
-
-
0029821869
-
A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains
-
Berson JF, Long D, Doranz BJ, et al. A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. J Virol 1996; 70: 6288-6295.
-
(1996)
J Virol
, vol.70
, pp. 6288-6295
-
-
Berson, J.F.1
Long, D.2
Doranz, B.J.3
-
26
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
Deng H, Liu R, Ellmeier W, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996; 381: 661-666.
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
-
27
-
-
0030002637
-
HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
-
Feng Y, Broder CC, Kennedy PE, et al. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996; 272: 872-877.
-
(1996)
Science
, vol.272
, pp. 872-877
-
-
Feng, Y.1
Broder, C.C.2
Kennedy, P.E.3
-
28
-
-
0032712246
-
Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity
-
LaBranche CC, Huffman TL, Romano J, et al. Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity. J Virol 1999; 73: 10310-10319.
-
(1999)
J Virol
, vol.73
, pp. 10310-10319
-
-
LaBranche, C.C.1
Huffman, T.L.2
Romano, J.3
-
30
-
-
0028023726
-
Structure of influenza haemagglutinin at the pH of membrane fusion
-
Bullough PA, Hughson FM, Skehel JJ, et al. Structure of influenza haemagglutinin at the pH of membrane fusion. Nature 1994; 371: 37-43.
-
(1994)
Nature
, vol.371
, pp. 37-43
-
-
Bullough, P.A.1
Hughson, F.M.2
Skehel, J.J.3
-
31
-
-
0027253445
-
A spring-loaded mechanism for the conformational change of influenza hemagglutinin
-
Carr CM, Kim PS. A spring-loaded mechanism for the conformational change of influenza hemagglutinin. Cell 1993; 73: 823-832.
-
(1993)
Cell
, vol.73
, pp. 823-832
-
-
Carr, C.M.1
Kim, P.S.2
-
32
-
-
0029072191
-
A molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: Implication for viral fusion
-
Chen CH, Matthews TJ, McDanal CB, et al. A molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: implication for viral fusion. J Virol 1995; 69: 3771-3777.
-
(1995)
J Virol
, vol.69
, pp. 3771-3777
-
-
Chen, C.H.1
Matthews, T.J.2
McDanal, C.B.3
-
33
-
-
0028834461
-
A trimeric structural domain of the HIV-1 transmembrane glycoprotein
-
Lu M, Blacklow SC, Kim PS. A trimeric structural domain of the HIV-1 transmembrane glycoprotein. Nat Struct Biol 1995; 2: 1075-1082.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 1075-1082
-
-
Lu, M.1
Blacklow, S.C.2
Kim, P.S.3
-
34
-
-
0034675886
-
Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion
-
Melikyan GB, Markosyan RM, Hemmati H, et al. Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion. J Cell Biol 2000; 151: 413-423.
-
(2000)
J Cell Biol
, vol.151
, pp. 413-423
-
-
Melikyan, G.B.1
Markosyan, R.M.2
Hemmati, H.3
-
35
-
-
0343365487
-
Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion
-
Munoz-Barroso I, Salzwedel K, Hunter E, et al. Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion. J Virol 1999; 73: 6089-6092.
-
(1999)
J Virol
, vol.73
, pp. 6089-6092
-
-
Munoz-Barroso, I.1
Salzwedel, K.2
Hunter, E.3
-
36
-
-
0031959601
-
Capture of an early fusion-active conformation of HIV-1 gp41
-
Furuta RA, Wild CT, Weng Y, et al. Capture of an early fusion-active conformation of HIV-1 gp41. Nat Struct Biol 1998; 5: 276-279.
-
(1998)
Nat Struct Biol
, vol.5
, pp. 276-279
-
-
Furuta, R.A.1
Wild, C.T.2
Weng, Y.3
-
37
-
-
0036796994
-
P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals
-
Meaden ER, Hoggard PG, Newton P, et al. P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals. J Antimicrob Chemother 2002; 50: 583-588.
-
(2002)
J Antimicrob Chemother
, vol.50
, pp. 583-588
-
-
Meaden, E.R.1
Hoggard, P.G.2
Newton, P.3
-
38
-
-
0035958776
-
P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: Potential for accelerated viral drug resistance?
-
Jones K, Bray PG, Khoo SH, et al. P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance? AIDS 2001; 15: 1353-1358.
-
(2001)
AIDS
, vol.15
, pp. 1353-1358
-
-
Jones, K.1
Bray, P.G.2
Khoo, S.H.3
-
39
-
-
0037110745
-
Impaired 2′,3′-dideoxy-3′-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11
-
Turriziani O, Schuetz JD, Pocher F, et al. Impaired 2′,3′- dideoxy-3′-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11. Biochem J 2002; 368: 325-332.
-
(2002)
Biochem J
, vol.368
, pp. 325-332
-
-
Turriziani, O.1
Schuetz, J.D.2
Pocher, F.3
-
40
-
-
0032879904
-
MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
-
Schuetz JD, Connelly MC, Sun D, et al. MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nat Med 1999; 5: 1048-1051.
-
(1999)
Nat Med
, vol.5
, pp. 1048-1051
-
-
Schuetz, J.D.1
Connelly, M.C.2
Sun, D.3
-
41
-
-
0036839699
-
Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2)
-
Williams GC, Liu A, Knipp G, et al. Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2). Antimicrob Agents Chemother 2002; 46: 3456-3462.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 3456-3462
-
-
Williams, G.C.1
Liu, A.2
Knipp, G.3
-
42
-
-
0026601827
-
Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates
-
Moore JP, McKeating JA, Huang YX, et al. Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates. J Virol 1992; 66: 235-243.
-
(1992)
J Virol
, vol.66
, pp. 235-243
-
-
Moore, J.P.1
McKeating, J.A.2
Huang, Y.X.3
-
43
-
-
0029096184
-
Safety, pharmacokinetics, and antiviral response of CD4-immunoglobulin G by intravenous bolus in AIDS and AIDS-related complex
-
Collier AC, Coombs RW, Katzenstein D, et al. Safety, pharmacokinetics, and antiviral response of CD4-immunoglobulin G by intravenous bolus in AIDS and AIDS-related complex. J Acquir Immune Defic Syndr Hum Retrovirol 1995; 10: 150-156.
-
(1995)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.10
, pp. 150-156
-
-
Collier, A.C.1
Coombs, R.W.2
Katzenstein, D.3
-
44
-
-
0026037210
-
Phase 1 study of recombinant human CD4-immunoglobulin G therapy of patients with AIDS and AIDS-related complex
-
Hodges TL, Kahn JO, Kaplan LD, et al. Phase 1 study of recombinant human CD4-immunoglobulin G therapy of patients with AIDS and AIDS-related complex. Antimicrob Agents Chemother 1991; 35: 2580-2586.
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 2580-2586
-
-
Hodges, T.L.1
Kahn, J.O.2
Kaplan, L.D.3
-
45
-
-
0028966285
-
Combination therapy with recombinant human soluble CD4-immunoglobulin G and zidovudine in patients with HIV infection: A phase I study
-
Meng TC, Fischl MA, Cheeseman SH, et al. Combination therapy with recombinant human soluble CD4-immunoglobulin G and zidovudine in patients with HIV infection: a phase I study. J Acquir Immune Defic Syndr Hum Retrovirol 1995; 8: 152-160.
-
(1995)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.8
, pp. 152-160
-
-
Meng, T.C.1
Fischl, M.A.2
Cheeseman, S.H.3
-
46
-
-
9144236197
-
Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1
-
Kuritzkes DR, Jacobson J, Powderly WG, et al. Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1. J Infect Dis 2004; 189: 286-291.
-
(2004)
J Infect Dis
, vol.189
, pp. 286-291
-
-
Kuritzkes, D.R.1
Jacobson, J.2
Powderly, W.G.3
-
47
-
-
0003339453
-
SCH C: Safety and antiviral effects of a CCR5 receptor antagonist in HIV-1-infected subjects
-
Seattle, USA, 24-28 February; Abstract 1
-
Reynes J, Rouzier R, Kanouni T, et al. SCH C: Safety and antiviral effects of a CCR5 receptor antagonist in HIV-1-infected subjects. In 9th Conference on Retroviruses and Opportunistic Infections, Seattle, USA, 24-28 February 2003; Abstract 1.
-
(2003)
9th Conference on Retroviruses and Opportunistic Infections
-
-
Reynes, J.1
Rouzier, R.2
Kanouni, T.3
-
48
-
-
2642563856
-
SCH D: Antiviral activity of a CCR5 receptor antagonist
-
San Francisco, USA, 8-11 February; Abstract 140LB
-
Schurmann D, Rouzier R, Nougarede R, et al. SCH D: Antiviral activity of a CCR5 receptor antagonist. In 11th Conference on Retroviruses and Opportunistic Infections, San Francisco, USA, 8-11 February 2004; Abstract 140LB.
-
(2004)
11th Conference on Retroviruses and Opportunistic Infections
-
-
Schurmann, D.1
Rouzier, R.2
Nougarede, R.3
-
49
-
-
3042802956
-
Effect of short term monotherapy with UK-427,857 on viral load in HIV-infected patients
-
Chicago, USA, 14-17 September; Abstract H-443
-
Pozniak AL, Fatkenheuer G, Johnson M, et al. Effect of short term monotherapy with UK-427,857 on viral load in HIV-infected patients. In 43rd Interscience Conference on Antiviral Agents and Chemotherapy, Chicago, USA, 14-17 September 2003; Abstract H-443.
-
(2003)
43rd Interscience Conference on Antiviral Agents and Chemotherapy
-
-
Pozniak, A.L.1
Fatkenheuer, G.2
Johnson, M.3
-
50
-
-
4544371685
-
Multiple dose study to investigate the safety of UK-427,857 (100 mg or 300 mg) BID for 28 days in healthy males and females
-
Chicago, USA, 14-17 September; Abstract H-874
-
Russel D, Bakhtyari A, Jazawi RP, et al. Multiple dose study to investigate the safety of UK-427,857 (100 mg or 300 mg) BID for 28 days in healthy males and females. In 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, USA, 14-17 September 2003; Abstract H-874.
-
(2003)
43rd Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Russel, D.1
Bakhtyari, A.2
Jazawi, R.P.3
-
51
-
-
0035846960
-
Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage
-
Kliger Y, Gallo SA, Peisajovich SG, et al. Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage. J Biol Chem 2001; 276: 1391-1397.
-
(2001)
J Biol Chem
, vol.276
, pp. 1391-1397
-
-
Kliger, Y.1
Gallo, S.A.2
Peisajovich, S.G.3
-
52
-
-
0028168944
-
Structural rearrangements in the transmembrane glycoprotein after receptor binding
-
Matthews TJ, Wild C, Chen CH, et al. Structural rearrangements in the transmembrane glycoprotein after receptor binding. Immunol Rev 1994; 140: 93-104.
-
(1994)
Immunol Rev
, vol.140
, pp. 93-104
-
-
Matthews, T.J.1
Wild, C.2
Chen, C.H.3
-
53
-
-
0026465468
-
A synthetic peptide inhibitor of human immunodeficiency virus replication: Correlation between solution structure and viral inhibition
-
Wild C, Oas T, McDanal C, et al. A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition. Proc Natl Acad Sci USA 1992; 89: 10537-10541.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10537-10541
-
-
Wild, C.1
Oas, T.2
McDanal, C.3
-
54
-
-
0029926552
-
HIV-1 membrane fusion mechanism: Structural studies of the interactions between biologically-active peptides from gp41
-
Lawless MK, Barney S, Guthrie KI, et al. HIV-1 membrane fusion mechanism: structural studies of the interactions between biologically-active peptides from gp41. Biochemistry 1996; 35: 13697-13708.
-
(1996)
Biochemistry
, vol.35
, pp. 13697-13708
-
-
Lawless, M.K.1
Barney, S.2
Guthrie, K.I.3
-
55
-
-
0035313589
-
Human immunodeficiency virus type 1 entry inhibitors PRO 542 and T-20 are potently synergistic in blocking virus-cell and cell-cell fusion
-
Nagashima KA, Thompson DA, Rosenfield SI, et al. Human immunodeficiency virus type 1 entry inhibitors PRO 542 and T-20 are potently synergistic in blocking virus-cell and cell-cell fusion. J Infect Dis 2001; 183: 1121-1125.
-
(2001)
J Infect Dis
, vol.183
, pp. 1121-1125
-
-
Nagashima, K.A.1
Thompson, D.A.2
Rosenfield, S.I.3
-
56
-
-
0031869099
-
A semiautomated fluorescence-based cell-to-cell fusion assay for gp120-gp41 and CD4 expressing cells
-
Pine PS, Weaver JL, Oravecz T, et al. A semiautomated fluorescence-based cell-to-cell fusion assay for gp120-gp41 and CD4 expressing cells. Exp Cell Res 1998; 240: 49-57.
-
(1998)
Exp Cell Res
, vol.240
, pp. 49-57
-
-
Pine, P.S.1
Weaver, J.L.2
Oravecz, T.3
-
57
-
-
0010459359
-
Virus sensitivity to T-20 and T-1249 is independent of coreceptor usage
-
Chicago, USA, 4-8 February; Abstract 473
-
Greenberg ML, McDanal CB, Stanfield-Oakley SA, et al. Virus sensitivity to T-20 and T-1249 is independent of coreceptor usage. In 8th Conference on Retroviruses and Opportunistic Infections, Chicago, USA, 4-8 February 2001; Abstract 473.
-
(2001)
8th Conference on Retroviruses and Opportunistic Infections
-
-
Greenberg, M.L.1
McDanal, C.B.2
Stanfield-Oakley, S.A.3
-
58
-
-
4444306550
-
Analysis of patient-derived HIV-1 isolates suggests a novel mechanism for decreased sensitivity to inhibition by enfuvirtide and T-649
-
Paris, France, 13-16 July; Abstract 801
-
Heil M, Decker JM, Chen J, et al. Analysis of patient-derived HIV-1 isolates suggests a novel mechanism for decreased sensitivity to inhibition by enfuvirtide and T-649. In 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment, Paris, France, 13-16 July 2003; Abstract 801.
-
(2003)
2nd International AIDS Society Conference on HIV Pathogenesis and Treatment
-
-
Heil, M.1
Decker, J.M.2
Chen, J.3
-
59
-
-
0037223692
-
Baseline susceptibility of primary human immunodeficiency virus type 1 to entry inhibitors
-
Labrosse B, Labernardiere JL, Dam E, et al. Baseline susceptibility of primary human immunodeficiency virus type 1 to entry inhibitors. J Virol 2003; 77: 1610-1613.
-
(2003)
J Virol
, vol.77
, pp. 1610-1613
-
-
Labrosse, B.1
Labernardiere, J.L.2
Dam, E.3
-
60
-
-
0033856458
-
Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120
-
Derdeyn CA, Decker JM, Sfakianos JN, et al. Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J Virol 2000; 74: 8358-8367.
-
(2000)
J Virol
, vol.74
, pp. 8358-8367
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
-
61
-
-
0034890660
-
Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor
-
Derdeyn CA, Decker JM, Sfakianos JN, et al. Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. J Virol 2001; 75: 8605-8614.
-
(2001)
J Virol
, vol.75
, pp. 8605-8614
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
-
62
-
-
0042895999
-
Analysis of baseline enfuvirtide (T20) susceptibility and coreceptor tropism in two Phase III study populations
-
Boston, USA, 10-14 February; Abstract 557
-
Whitcomb JM, Huang W, Fransen S, et al. Analysis of baseline enfuvirtide (T20) susceptibility and coreceptor tropism in two Phase III study populations. In 10th Conference on Retroviruses and Opportunistic Infections, Boston, USA, 10-14 February 2003; Abstract 557.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Whitcomb, J.M.1
Huang, W.2
Fransen, S.3
-
63
-
-
3042662701
-
Determinants of susceptibility to enfuvirtide map to gp41 in enfuvirtide-naive HIV-1
-
Los Cabos, Mexico, 10-14 June; Abstract 56
-
Stanfield-Oakley SA, Jeffrey J, McDanal CB, et al. Determinants of susceptibility to enfuvirtide map to gp41 in enfuvirtide-naive HIV-1. In XII Intenational HIV Drug Resistance Workshop, Los Cabos, Mexico, 10-14 June 2003; Abstract 56.
-
(2003)
XII Intenational HIV Drug Resistance Workshop
-
-
Stanfield-Oakley, S.A.1
Jeffrey, J.2
McDanal, C.B.3
-
64
-
-
0012823617
-
Baseline and on-treatment susceptibility to enfuvirtide seen in TORO 1 and TORO 2 through 24 weeks
-
Boston, USA, 10-14 February; Abstract 141
-
Greenberg ML, Melby T, Sista P, et al. Baseline and on-treatment susceptibility to enfuvirtide seen in TORO 1 and TORO 2 through 24 weeks. In 10th Conference on Retroviruses and Opportunistic Infections, Boston, USA, 10-14 February 2003; Abstract 141.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Greenberg, M.L.1
Melby, T.2
Sista, P.3
-
65
-
-
0008259164
-
The fusion inhibitors T-20 and T-1249 demonstrate potent in vitro antiviral activity against clade B HIV-1 isolates resistant to reverse transcriptase and protease inhibitors and non-B clades
-
Scottsdale, USA, 4-8 June; Abstract 2
-
Sista P, Melby T, Dhingra U, et al. The fusion inhibitors T-20 and T-1249 demonstrate potent in vitro antiviral activity against clade B HIV-1 isolates resistant to reverse transcriptase and protease inhibitors and non-B clades. In 5th International Workshop on HIV Drug Resistance and Treatment Strategies, Scottsdale, USA, 4-8 June 2001; Abstract 2.
-
(2001)
5th International Workshop on HIV Drug Resistance and Treatment Strategies
-
-
Sista, P.1
Melby, T.2
Dhingra, U.3
-
66
-
-
0031729823
-
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
-
Kilby JM, Hopkins S, Venetta TM, et al. Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat Med 1998; 4: 1302-1307.
-
(1998)
Nat Med
, vol.4
, pp. 1302-1307
-
-
Kilby, J.M.1
Hopkins, S.2
Venetta, T.M.3
-
67
-
-
0036066762
-
The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults
-
Kilby JM, Lalezari JP, Eron JJ, et al. The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults. AIDS Res Hum Retroviruses 2002; 18: 685-693.
-
(2002)
AIDS Res Hum Retroviruses
, vol.18
, pp. 685-693
-
-
Kilby, J.M.1
Lalezari, J.P.2
Eron, J.J.3
-
68
-
-
0037471311
-
A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy
-
Lalezari JP, Eron JJ, Carlson M, et al. A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy. AIDS 2003; 17: 691-698.
-
(2003)
AIDS
, vol.17
, pp. 691-698
-
-
Lalezari, J.P.1
Eron, J.J.2
Carlson, M.3
-
69
-
-
0032839921
-
Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: Phenotypic resistance to protease inhibitors predicts outcome of therapy
-
Piketty C, Race E, Castiel P, et al. Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: phenotypic resistance to protease inhibitors predicts outcome of therapy. AIDS 1999; 13: F71-F77.
-
(1999)
AIDS
, vol.13
-
-
Piketty, C.1
Race, E.2
Castiel, P.3
-
70
-
-
10744229122
-
A controlled Phase II trial assessing three doses of enfuvirtide (T-20) in combination with abacavir, amprenavir, ritonavir, and efavirenz in non-nucleoside reverse transcriptase inhibitor-naive HIV-infected adults
-
Lalezari J, DeJesus E, Northfelt D, et al. A controlled Phase II trial assessing three doses of enfuvirtide (T-20) in combination with abacavir, amprenavir, ritonavir, and efavirenz in non-nucleoside reverse transcriptase inhibitor-naive HIV-infected adults. Antivir Ther 2003; 8: 279-287.
-
(2003)
Antivir Ther
, vol.8
, pp. 279-287
-
-
Lalezari, J.1
DeJesus, E.2
Northfelt, D.3
-
71
-
-
2342614844
-
Safety, tolerability and plasma pharmacokinetics of high-strength formulations of enfuvirtide (T-20) in treatment-experienced HIV-1-infected patients
-
Wheeler DA, Lalezari JP, Kilby JM, et al. Safety, tolerability and plasma pharmacokinetics of high-strength formulations of enfuvirtide (T-20) in treatment-experienced HIV-1-infected patients. J Clin Virol 2004; 30: 183-190.
-
(2004)
J Clin Virol
, vol.30
, pp. 183-190
-
-
Wheeler, D.A.1
Lalezari, J.P.2
Kilby, J.M.3
-
72
-
-
0036335809
-
Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: Inverse Gaussian density absorption and 2-compartment disposition
-
Zhang X, Nieforth K, Lang J, et al. Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: Inverse Gaussian density absorption and 2-compartment disposition. Clin Pharmacol Ther 2002; 72: 10-19.
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 10-19
-
-
Zhang, X.1
Nieforth, K.2
Lang, J.3
-
73
-
-
0042885473
-
Influence of subcutaneous injection site on the steady-state pharmacokinetics of enfuvirtide (T-20) in HIV-1-infected patients
-
Lalezari JP, Patel IH, Zhang X, et al. Influence of subcutaneous injection site on the steady-state pharmacokinetics of enfuvirtide (T-20) in HIV-1-infected patients. J Clin Virol 2003; 28: 217-222.
-
(2003)
J Clin Virol
, vol.28
, pp. 217-222
-
-
Lalezari, J.P.1
Patel, I.H.2
Zhang, X.3
-
74
-
-
2942613517
-
Pharmacokinetics of enfuvirtide in pediatric HIV infected patients receiving combination therapy
-
Paris, France, 13-16 July; Abstract 841
-
Bellibas SE, Siddique Z, Dorr A, et al. Pharmacokinetics of enfuvirtide in pediatric HIV infected patients receiving combination therapy. In 2nd IAS Conference on HIV Pathogenesis and Treatment, Paris, France, 13-16 July 2003; Abstract 841.
-
(2003)
2nd IAS Conference on HIV Pathogenesis and Treatment
-
-
Bellibas, S.E.1
Siddique, Z.2
Dorr, A.3
-
75
-
-
0036020193
-
Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children
-
Church JA, Cunningham C, Hughes M, et al. Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children. Pediatr Infect Dis J 2002; 21: 653-659.
-
(2002)
Pediatr Infect Dis J
, vol.21
, pp. 653-659
-
-
Church, J.A.1
Cunningham, C.2
Hughes, M.3
-
76
-
-
2442698673
-
Chronic subcutaneous T-20 (enfuvirtide) in HIV infected children: 48 Week outcome
-
Chicago, USA, 24-27 October; Abstract 441
-
Cunningham C, Church J, Hughes M, et al. Chronic subcutaneous T-20 (enfuvirtide) in HIV infected children: 48 week outcome. In 40th Annual Meeting of IDSA (Infectious Diseases Society of America), Chicago, USA, 24-27 October 2002; Abstract 441.
-
(2002)
40th Annual Meeting of IDSA (Infectious Diseases Society of America)
-
-
Cunningham, C.1
Church, J.2
Hughes, M.3
-
77
-
-
2942594069
-
Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus type 1-infected patients
-
Zhang X, Lalezari JP, Badley AD, et al. Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus type 1-infected patients. Clin Pharmacol Ther 2004; 75: 558-568.
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 558-568
-
-
Zhang, X.1
Lalezari, J.P.2
Badley, A.D.3
-
78
-
-
0242469076
-
Lack of enzyme-inducing effect of rifampicin on the pharmacokinetics of enfuvirtide
-
Boyd MA, Zhang X, Dorr A, et al. Lack of enzyme-inducing effect of rifampicin on the pharmacokinetics of enfuvirtide. J Clin Pharmacol 2003; 43: 1382-1391.
-
(2003)
J Clin Pharmacol
, vol.43
, pp. 1382-1391
-
-
Boyd, M.A.1
Zhang, X.2
Dorr, A.3
-
79
-
-
2942642589
-
Lack of interaction between enfuvirtide and ritonavir or ritonavir-boosted saquinavir in HIV-1-infected patients
-
Ruxrungtham K, Boyd M, Bellibas SE, et al. Lack of interaction between enfuvirtide and ritonavir or ritonavir-boosted saquinavir in HIV-1-infected patients. J Clin Pharmacol 2004; 44(7): 793-803.
-
(2004)
J Clin Pharmacol
, vol.44
, Issue.7
, pp. 793-803
-
-
Ruxrungtham, K.1
Boyd, M.2
Bellibas, S.E.3
-
80
-
-
0038576281
-
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
-
Lalezari JP, Henry K, O'Hearn M, et al. Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. N Engl J Med 2003; 348: 2175-2185.
-
(2003)
N Engl J Med
, vol.348
, pp. 2175-2185
-
-
Lalezari, J.P.1
Henry, K.2
O'Hearn, M.3
-
81
-
-
0037849954
-
Efficacy of enfuvirtide in patients infected with drug-resistant human immunodeficiency virus type 1 in Europe and Australia
-
Lazzarin A, Clotet B, Cooper D, et al. Efficacy of enfuvirtide in patients infected with drug-resistant human immunodeficiency virus type 1 in Europe and Australia. N Engl J Med 2003; 348: 2186-2195.
-
(2003)
N Engl J Med
, vol.348
, pp. 2186-2195
-
-
Lazzarin, A.1
Clotet, B.2
Cooper, D.3
-
82
-
-
4544386796
-
Enfuvirtide TORO studies: 48 Week results confirm 24 week findings
-
Paris, France, 13-16 July; Abstract LB2
-
Katlama C, Arastéh K, Clotet B, et al. Enfuvirtide TORO studies: 48 week results confirm 24 week findings. In 2nd International AIDS Society Meeting, Paris, France, 13-16 July 2003; Abstract LB2.
-
(2003)
2nd International AIDS Society Meeting
-
-
Katlama, C.1
Arastéh, K.2
Clotet, B.3
-
83
-
-
3042512327
-
Subgroup analysis of baseline (BL) susceptibility and early virological response to enfuvirtide in the combined TORO studies
-
Los Cabos, Mexico, 10-14 June; Abstract 55
-
Sista P, Melby T, Greenberg ML, et al. Subgroup analysis of baseline (BL) susceptibility and early virological response to enfuvirtide in the combined TORO studies. In XII International HIV Drug Resistance Workshop, Los Cabos, Mexico, 10-14 June 2003; Abstract 55.
-
(2003)
XII International HIV Drug Resistance Workshop
-
-
Sista, P.1
Melby, T.2
Greenberg, M.L.3
-
84
-
-
0012013998
-
Enfuvirtide (T-20) in combination with an optimized background (OB) regimen vs. OB alone: Week 24 response among categories of treatment experience and baseline (BL) HIV antiretroviral (ARV) resistance
-
San Diego, USA, 27-30 September; Abstract 3232
-
Lalezari J, Henry K, O'Hearn M, et al. Enfuvirtide (T-20) in combination with an optimized background (OB) regimen vs. OB alone: week 24 response among categories of treatment experience and baseline (BL) HIV antiretroviral (ARV) resistance. In 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, USA, 27-30 September 2002; Abstract 3232.
-
(2002)
42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Lalezari, J.1
Henry, K.2
O'Hearn, M.3
-
85
-
-
0141954433
-
Enfuvirtide (T-20) in combination with an optimized background (OB) regimen vs. OB alone: Week 24 response among categories of baseline (BL) demographics, treatment experience, and HIV anti-retroviral (ARV) resistance
-
Glasgow, UK, 17-21 November; Abstract PL14.3
-
Lange J, Lazzarin A, Clotet B, et al. Enfuvirtide (T-20) in combination with an optimized background (OB) regimen vs. OB alone: week 24 response among categories of baseline (BL) demographics, treatment experience, and HIV anti-retroviral (ARV) resistance. In 6th International Congress on Drug Therapy in HIV Infection, Glasgow, UK, 17-21 November 2002; Abstract PL14.3.
-
(2002)
6th International Congress on Drug Therapy in HIV Infection
-
-
Lange, J.1
Lazzarin, A.2
Clotet, B.3
-
86
-
-
1642357851
-
Analysis of virological response of enfuvirtide in TORO: Implications for patient management
-
Paris, France, 13-16 July; Abstract 116
-
Montaner J, DeMasi R, Delehanty J, et al. Analysis of virological response of enfuvirtide in TORO: implications for patient management. In 2nd IAS Conference on HIV Pathogenesis and Treatment, Paris, France, 13-16 July 2003; Abstract 116.
-
(2003)
2nd IAS Conference on HIV Pathogenesis and Treatment
-
-
Montaner, J.1
DeMasi, R.2
Delehanty, J.3
-
87
-
-
1642314025
-
Efficacy of enfuvirtide in subgroups of patients through 48 weeks of therapy in the TORO trials
-
Warsaw, Poland, 25-29 October; Abstract 7.3/15
-
Walmsley S, Clotet B, Cooper D, et al. Efficacy of enfuvirtide in subgroups of patients through 48 weeks of therapy in the TORO trials. In 9th European AIDS Conference, Warsaw, Poland, 25-29 October 2003; Abstract 7.3/15.
-
(2003)
9th European AIDS Conference
-
-
Walmsley, S.1
Clotet, B.2
Cooper, D.3
-
88
-
-
1642310750
-
Durability of response of enfuvirtide through 48 weeks in the TORO trials
-
Chicago, USA, 14-17 September; Abstract H-835
-
Trottier B, Arastéh K, Henry K, et al. Durability of response of enfuvirtide through 48 weeks in the TORO trials. In 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, USA, 14-17 September 2003; Abstract H-835.
-
(2003)
43rd Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Trottier, B.1
Arastéh, K.2
Henry, K.3
-
89
-
-
0011581041
-
Tolerability of enfuvirtide (T-20) during chronic therapy in Phase II trials
-
San Diego, USA, 27-30 September; Abstract H-171
-
Drobnes C, Fang L, Nelson E, et al. Tolerability of enfuvirtide (T-20) during chronic therapy in Phase II trials. In 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, USA, 27-30 September 2002; Abstract H-171.
-
(2002)
42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Drobnes, C.1
Fang, L.2
Nelson, E.3
-
90
-
-
1642414599
-
Safety of enfuvirtide (ENF) through 48 weeks of therapy in the TORO trials
-
Chicago, USA, 14-17 September; Abstract H-836
-
Eron J, Delfraissy J-F, Kuritzkes DR, et al. Safety of enfuvirtide (ENF) through 48 weeks of therapy in the TORO trials. In 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, USA, 14-17 September 2003; Abstract H-836.
-
(2003)
43rd Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Eron, J.1
Delfraissy, J.-F.2
Kuritzkes, D.R.3
-
91
-
-
19244363224
-
Community-acquired pneumonia in a cohort of former injection drug users with and without human immunodeficiency virus infection: Incidence, etiologies, and clinical aspects
-
Boschini A, Smacchia C, Di Fine M, et al. Community-acquired pneumonia in a cohort of former injection drug users with and without human immunodeficiency virus infection: incidence, etiologies, and clinical aspects. Clin Infect Dis 1996; 23: 107-113.
-
(1996)
Clin Infect Dis
, vol.23
, pp. 107-113
-
-
Boschini, A.1
Smacchia, C.2
Di Fine, M.3
-
92
-
-
0033913932
-
Effect of antiretroviral therapy on the incidence of bacterial pneumonia in patients with advanced HIV infection
-
Sullivan JH, Moore RD, Keruly JC, et al. Effect of antiretroviral therapy on the incidence of bacterial pneumonia in patients with advanced HIV infection. Am J Respir Crit Care Med 2000; 162: 64-67.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 64-67
-
-
Sullivan, J.H.1
Moore, R.D.2
Keruly, J.C.3
-
93
-
-
0033735970
-
Effect of highly active antiretroviral therapy on the incidence of bacterial pneumonia in HIV-infected subjects
-
de Gaetano DK, Bertagnolio S, Tumbarello M, et al. Effect of highly active antiretroviral therapy on the incidence of bacterial pneumonia in HIV-infected subjects. Int J Antimicrob Agents 2000; 16: 357-360.
-
(2000)
Int J Antimicrob Agents
, vol.16
, pp. 357-360
-
-
De Gaetano, D.K.1
Bertagnolio, S.2
Tumbarello, M.3
-
94
-
-
0029074827
-
Bacterial pneumonia in persons infected with the human immunodeficiency virus
-
Pulmonary Complications of HIV Infection Study Group
-
Hirschtick RE, Glassroth J, Jordan MC, et al. Bacterial pneumonia in persons infected with the human immunodeficiency virus. Pulmonary Complications of HIV Infection Study Group. N Engl J Med 1995; 333: 845-851.
-
(1995)
N Engl J Med
, vol.333
, pp. 845-851
-
-
Hirschtick, R.E.1
Glassroth, J.2
Jordan, M.C.3
-
95
-
-
0347386443
-
Guillain-Barre syndrome associated with immune reconstitution
-
Piliero PJ, Fish DG, Preston S, et al. Guillain-Barre syndrome associated with immune reconstitution. Clin Infect Dis 2003; 36: e111-e114.
-
(2003)
Clin Infect Dis
, vol.36
-
-
Piliero, P.J.1
Fish, D.G.2
Preston, S.3
-
96
-
-
0034892978
-
Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein
-
de Rosny E, Vassell R, Wingfield PT, et al. Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein. J Virol 2001; 75: 8859-8863.
-
(2001)
J Virol
, vol.75
, pp. 8859-8863
-
-
De Rosny, E.1
Vassell, R.2
Wingfield, P.T.3
-
97
-
-
0009834963
-
Effects of peptide-induced humoral responses and preexisting antibodies in nonhuman primates and HIV-infected patients following chronic administration of T-20
-
San Francisco, USA, 30 January-2 February; Abstract 502
-
DiMassimo B, Milam D, Rusnak P, et al. Effects of peptide-induced humoral responses and preexisting antibodies in nonhuman primates and HIV-infected patients following chronic administration of T-20. In 7th Conference on Retroviruses and Opportunistic Infections, San Francisco, USA, 30 January-2 February 2000; Abstract 502.
-
(2000)
7th Conference on Retroviruses and Opportunistic Infections
-
-
DiMassimo, B.1
Milam, D.2
Rusnak, P.3
-
98
-
-
9144264190
-
Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide
-
Walmsley S, Henry K, Katlama C, et al. Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide. J Infect Dis 2003; 188: 1827-1833.
-
(2003)
J Infect Dis
, vol.188
, pp. 1827-1833
-
-
Walmsley, S.1
Henry, K.2
Katlama, C.3
-
99
-
-
0031883832
-
Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides
-
Rimsky LT, Shugars DC, Matthews TJ. Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides. J Virol 1998; 72: 986-993.
-
(1998)
J Virol
, vol.72
, pp. 986-993
-
-
Rimsky, L.T.1
Shugars, D.C.2
Matthews, T.J.3
-
100
-
-
4544288657
-
Impact of HIV-1 gp41 amino acid substitutions (positions 36-45) on susceptibility to T-20 (enfuvirtide) in vitro: Analysis of primary virus isolates recovered from patients during chronic enfuvirtide treatment and site directed mutants in NL4-3
-
Seville, Spain, 2-5 July; Abstract 22
-
Mink M, Greenberg ML, Mosier S, et al. Impact of HIV-1 gp41 amino acid substitutions (positions 36-45) on susceptibility to T-20 (enfuvirtide) in vitro: Analysis of primary virus isolates recovered from patients during chronic enfuvirtide treatment and site directed mutants in NL4-3. In XI International HIV Drug Resistance Workshop, Seville, Spain, 2-5 July 2002; Abstract 22.
-
(2002)
XI International HIV Drug Resistance Workshop
-
-
Mink, M.1
Greenberg, M.L.2
Mosier, S.3
-
101
-
-
0036090585
-
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
-
Wei X, Decker JM, Liu H, et al. Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrob Agents Chemother 2002; 46: 1896-1905.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1896-1905
-
-
Wei, X.1
Decker, J.M.2
Liu, H.3
-
102
-
-
1642294438
-
Correlation of gp41 binding and antiviral potencies of the fusion inhibitor T-20 using clinical trial isolate-derived sequences
-
Chicago, USA, 4-8 February; Abstract 474
-
Mink M, Janumpalli S, Davison D, et al. Correlation of gp41 binding and antiviral potencies of the fusion inhibitor T-20 using clinical trial isolate-derived sequences. In 8th Conference on Retroviruses and Opportunistic Infections, Chicago, USA, 4-8 February 2001; Abstract 474.
-
(2001)
8th Conference on Retroviruses and Opportunistic Infections
-
-
Mink, M.1
Janumpalli, S.2
Davison, D.3
-
103
-
-
0003248156
-
A week 48 assessment of high strength T-20 formulations in multi-class experienced patients
-
Seattle, USA, 24-28 February; Abstract 417-W
-
Wheat LJ, Lalezari J, Kilby JM, et al. A week 48 assessment of high strength T-20 formulations in multi-class experienced patients. In 9th Conference on Retroviruses and Opportunistic Infections, Seattle, USA, 24-28 February 2002; Abstract 417-W.
-
(2002)
9th Conference on Retroviruses and Opportunistic Infections
-
-
Wheat, L.J.1
Lalezari, J.2
Kilby, J.M.3
-
104
-
-
0344453691
-
Enfuvirtide (T-20) and T-1249 resistance: Observations from Phase II clinical trials of enfuvirtide in combination with oral antiretrovirals (ARVs) and a Phase I/II dose-ranging monotherapy trial of T-1249
-
Seville, Spain, 2-5 July; Abstract 128
-
Greenberg ML, Sista P, Miralles G, et al. Enfuvirtide (T-20) and T-1249 resistance: observations from Phase II clinical trials of enfuvirtide in combination with oral antiretrovirals (ARVs) and a Phase I/II dose-ranging monotherapy trial of T-1249. In XI International HIV Drug Resistance Workshop, Seville, Spain, 2-5 July 2002; Abstract 128.
-
(2002)
XI International HIV Drug Resistance Workshop
-
-
Greenberg, M.L.1
Sista, P.2
Miralles, G.3
-
105
-
-
3042564043
-
Characterization of baseline and treatment-emergent resistance to T-20 (enfuvirtide) observed in phase II clinical trials: Substitutions in gp41 amino acids 36-45 and enfuvirtide susceptibility of virus isolates
-
Seville, Spain, 2-5 July; Abstract 21
-
Sista P, Melby T, Greenberg ML, et al. Characterization of baseline and treatment-emergent resistance to T-20 (enfuvirtide) observed in phase II clinical trials: substitutions in gp41 amino acids 36-45 and enfuvirtide susceptibility of virus isolates. In XI International HIV Drug Resistance Workshop, Seville, Spain, 2-5 July 2002; Abstract 21.
-
(2002)
XI International HIV Drug Resistance Workshop
-
-
Sista, P.1
Melby, T.2
Greenberg, M.L.3
-
106
-
-
4544289304
-
Evolution of HR1 and HR2 mutations in HIV-1 gp41 associated with long-term enfuvirtide therapy
-
San Francisco, USA, 8-11 February; Abstract 659
-
Xu L, Pozniak A, Wildfire A, et al. Evolution of HR1 and HR2 mutations in HIV-1 gp41 associated with long-term enfuvirtide therapy. In 11th Conference on Retroviruses and Oppoprtunistic Infections, San Francisco, USA, 8-11 February 2004; Abstract 659.
-
(2004)
11th Conference on Retroviruses and Oppoprtunistic Infections
-
-
Xu, L.1
Pozniak, A.2
Wildfire, A.3
-
107
-
-
0030970693
-
Core structure of gp41 from the HIV envelope glycoprotein
-
Chan DC, Pass D, Berger JM, et al. Core structure of gp41 from the HIV envelope glycoprotein. Cell 1997; 89: 263-273.
-
(1997)
Cell
, vol.89
, pp. 263-273
-
-
Chan, D.C.1
Pass, D.2
Berger, J.M.3
-
108
-
-
0036708580
-
Subcutaneous injection survey: Psychometric evaluation of a treatment satisfaction instrument associated with a novel HIV medication
-
Green J, Kleinman L, Ciesla G, et al. Subcutaneous injection survey: psychometric evaluation of a treatment satisfaction instrument associated with a novel HIV medication. HIV Clin Trials 2002; 3: 387-395.
-
(2002)
HIV Clin Trials
, vol.3
, pp. 387-395
-
-
Green, J.1
Kleinman, L.2
Ciesla, G.3
-
109
-
-
0142186214
-
Patient acceptance of self-injected enfuvirtide at 8 and 24 weeks
-
Cohen C, Hellinger J, Johnson M, et al. Patient acceptance of self-injected enfuvirtide at 8 and 24 weeks. HIV Clin Trials 2003; 4: 347-357.
-
(2003)
HIV Clin Trials
, vol.4
, pp. 347-357
-
-
Cohen, C.1
Hellinger, J.2
Johnson, M.3
|