Proteasome inhibition interferes with Gag polyprotein processing, release, and maturation of HIV-1 and HIV-2

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 24, 2000, Pages 13057-13062

  Schubert, Ulrich ^a,c,d   Ott, David E ^b   Chertova, Elena N ^b   Welker, Reinhold ^c   Tessmer, Uwe ^c   Princiotta, Michael F ^a   Bennink, Jack R ^a,d   Kräusslich, Hans Georg ^c   Yewdell, Jonathan W ^a,d  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b SAIC FREDERICK INC   (United States)

^c LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; PROTEASOME; PROTEINASE; VIRUS ENVELOPE PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN TRANSPORT; VIRION; VIROGENESIS; VIRUS ASSEMBLY; VIRUS REPLICATION;

CELL LINE; CYSTEINE ENDOPEPTIDASES; GENE PRODUCTS, GAG; GENE PRODUCTS, VPU; HELA CELLS; HIV-1; HIV-2; HUMANS; KINETICS; MULTIENZYME COMPLEXES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; UBIQUITINS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0034700088     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.24.13057     Document Type: Article

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