Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions

Journal of Virology

Volumn 77, Issue 19, 2003, Pages 10528-10536

  Guo, Qi ^a   Ho, Hsu Tso ^a   Dicker, Ira ^a   Fan, Li ^a   Zhou, Nannan ^a   Friborg, Jacques ^a   Wang, Tao ^a   McAuliffe, Brian V ^a   Wang, Hwei Gene Heidi ^a   Rose, Ronald E ^a   Fang, Hua ^a   Scarnati, Helen T ^a   Langley, David R ^a   Meanwell, Nicholas A ^a   Abraham, Ralph ^a   Colonno, Richard J ^a   Lin, Pin Fang ^a  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 BENZOYL 1 [(4 METHOXY 1H PYRROLO[2,3 B]PYRIDIN 3 YL)OXOACETYL] 2 METHYLPIPERAZINE; ANTIRETROVIRUS AGENT; ANTIVIRUS AGENT; CD4 ANTIGEN; CD4 IMMUNOGLOBULIN G2; ENFUVIRTIDE; GLYCOPROTEIN GP 120; SC 351125; T 1249; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHEMICAL ANALYSIS; CLINICAL TRIAL; COMPETITIVE INHIBITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; EMBRYO; GENETIC ANALYSIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; STOICHIOMETRY; VALIDATION PROCESS; VIRUS INHIBITION;

ANIMALS; ANTI-HIV AGENTS; ANTIGENS, CD4; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; CRICETINAE; HIV ENVELOPE PROTEIN GP120; HIV-1; MICE; PIPERAZINES;

EID: 0141856289     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.19.10528-10536.2003     Document Type: Article

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