Localized Changes in the gp120 Envelope Glycoprotein Confer Resistance to Human Immunodeficiency Virus Entry Inhibitors BMS-806 and #155

Journal of Virology

Volumn 78, Issue 7, 2004, Pages 3742-3752

  Madani, Navid ^a,b   Perdigoto, Ana Luisa ^a   Srinivasan, Kumar ^a,b   Cox, Jason M ^d   Chruma, Jason J ^d   LaLonde, Judith ^e   Head, Martha ^e   Smith III, Amos B ^d   Sodroski, Joseph G ^a,b,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 BENZOYL 1 [(4 METHOXY 1H PYRROLO[2,3 B]PYRIDIN 3 YL)OXOACETYL] 2 METHYLPIPERAZINE; AMINO ACID; ANTIRETROVIRUS AGENT; CARBOHYDRATE; CD4 ANTIGEN; COMPOUND 155; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; PHENYLALANINE; UNCLASSIFIED DRUG; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BMS-378806; PIPERAZINE DERIVATIVE;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG RESISTANCE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INDUCTION; AMINO ACID SUBSTITUTION; ANIMAL; ANTIBIOTIC RESISTANCE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DOG; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SUBSTITUTION; ANIMALS; ANTI-HIV AGENTS; CELL LINE; DOGS; DRUG RESISTANCE, VIRAL; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MODELS, MOLECULAR; PHENYLALANINE; PIPERAZINES; PROTEIN STRUCTURE, TERTIARY;

EID: 1842562351     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.7.3742-3752.2004     Document Type: Article

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