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Volumn 272, Issue 5270, 1996, Pages 1955-1958

CC CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GUANINE NUCLEOTIDE BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES; RECEPTOR PROTEIN; RECOMBINANT CC CKR5; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

EID: 0030018156     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.272.5270.1955     Document Type: Article
Times cited : (2482)

References (34)
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    • C. Combadiere, S. K. Ahuja, P. M. Murphy, J. Biol. Chem. 270, 16491 (1995), correction ibid., p. 30235 (1995); C. Combadiere, S. K. Ahuja, P. M. Murphy, Mol. Biol. Cell 6, 224 (1995); C. Combadiere, S. K. Ahuja, H. L. Tiffany, P. M. Murphy, J. Leukocyte Biol. 60, 147 (1996); Genbank accession number U57840.
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    • C. Combadiere, S. K. Ahuja, P. M. Murphy, J. Biol. Chem. 270, 16491 (1995), correction ibid., p. 30235 (1995); C. Combadiere, S. K. Ahuja, P. M. Murphy, Mol. Biol. Cell 6, 224 (1995); C. Combadiere, S. K. Ahuja, H. L. Tiffany, P. M. Murphy, J. Leukocyte Biol. 60, 147 (1996); Genbank accession number U57840.
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    • note
    • CC CKR5 cDNA was excised from plasmid p8.5 (22) [cDNA in pBluescript (Stratagene)] by Sma I-Xho I digestion (Sma I digestion eliminated most of the 5′ untranslated region). The Sma I-Xho I fragment was blunt-ended using the Klenow fragment of Escherichia coli DNA polymerase and ligated into the Stu I site of plasmid pSC59. The resulting plasmid, designated pGA9-CKR5, contains the CC CKR5 cDNA linked to a strong synthetic early-late vaccinia promoter (28).
  • 34
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    • note
    • G.A. was supported by the Dr. Nathan Davis Award from the American Medical Association Education and Research Foundation awarded to E.A.B.; C.C. and C.C.B. are recipients of NIH Intramural Research Training Awards; Y.F. is a recipient of a National Research Council Research Associate fellowship. Support was provided by the NIH Intramural AIDS Targeted Antiviral Program. We are grateful to P. Earl, NIAID, for helpful comments on the manuscript.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.