Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity

Journal of Experimental Medicine

Volumn 187, Issue 8, 1998, Pages 1215-1224

  Mack, Matthias ^a   Luckow, Bruno ^a   Nelson, Peter J ^a   Cihak, Josef ^a   Simmons, Graham ^b   Clapham, Paul R ^b   Signoret, Nathalie ^c   Marsh, Mark ^c   Stangassinger, Manfred ^a   Borlat, Fréderic ^d,e   Wells, Timothy N C ^d,e   Schlöndorff, Detlef ^a   Proudfoot, Amanda E I ^d  

^a UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d GLAXOSMITHKLINE   (United States)

^e SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; RANTES;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CHO CELL; ENDOCYTOSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERNALIZATION; MONONUCLEAR CELL; NONHUMAN; OSTEOSARCOMA CELL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTI-HIV AGENTS; BIOLOGICAL TRANSPORT; CHO CELLS; CRICETINAE; DOWN-REGULATION; ENDOCYTOSIS; ENDOSOMES; HIV-1; HUMANS; RANTES; RECEPTORS, CCR5;

EID: 0032550337     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.8.1215     Document Type: Article

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