Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion

Journal of Cell Biology

Volumn 151, Issue 2, 2000, Pages 413-423

  Melikyan, Grigory B ^a   Markosyan, Ruben M ^a   Hemmati, Hila ^a   Delmedico, Mary K ^b   Lambert, Dennis M ^b   Cohen, Fredric S ^a  

^a RUSH MEDICAL COLLEGE   (United States)

^b Trimeris Inc   (United States)

Author keywords

Fusion intermediates; Fusion kinetics; Fusion pore; Hemifusion; Inhibitory peptides

Indexed keywords

INHIBITOR PROTEIN; LYSOPHOSPHATIDYLCHOLINE; PROTEIN GP41; UNCLASSIFIED DRUG; VIRUS FUSION PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; KINETICS; LIPID MEMBRANE; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; TEMPERATURE; VIRUS ENVELOPE;

CD4-POSITIVE T-LYMPHOCYTES; HIV ENVELOPE PROTEIN GP41; HIV-1; LYSOPHOSPHATIDYLCHOLINES; MEMBRANE FUSION; MODELS, BIOLOGICAL; MOTION; PROTEIN CONFORMATION; RECEPTORS, CXCR4; TEMPERATURE; THERMODYNAMICS;

EID: 0034675886     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.151.2.413     Document Type: Article

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