A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 19, 2003, Pages 11013-11018

  Lin, Pin Fang ^a   Blair, Wade ^a   Wang, Tao ^a   Spicer, Timothy ^a   Guo, Qi ^a   Zhou, Nannan ^a   Gong, Yi Fei ^a   Wang, H G Heidi ^a   Rose, Ronald ^a   Yamanaka, Gregory ^a   Robinson, Brett ^a   Li, Chang Ben ^a   Fridell, Robert ^a   Deminie, Carol ^a   Demers, Gwendeline ^a   Yang, Zheng ^a   Zadjura, Lisa ^a   Meanwell, Nicholas ^a   Colonno, Richard ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 BENZOYL 1 [(4 METHOXY 1H PYRROLO[2,3 B]PYRIDIN 3 YL)OXOACETYL] 2 METHYLPIPERAZINE; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; ENVELOPE PROTEIN; GLYCOPROTEIN GP 120; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL GROWTH; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SAFETY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; RETROVIRUS; SIMIAN IMMUNODEFICIENCY VIRUS; SPECIES COMPARISON; TOXICITY TESTING; VIRUS ENVELOPE; VIRUS INHIBITION; VIRUS ISOLATION;

ANIMALS; ANTIGENS, CD4; CELL LINE; DOGS; HIV FUSION INHIBITORS; HIV-1; MACACA FASCICULARIS; PIPERAZINES; RATS;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; RNA VIRUSES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0141703204     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1832214100     Document Type: Article

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