-
1
-
-
0009505878
-
R165335-TMC125, a novel non nucleoside reverse transcriptase inhibitor (NNRTI) with nanomolar activity against NNRTI resistant HIV strains
-
Toronto, Canada, 17-20 September 2000.
-
Andries, K., de Béthune, M.- P., Kukla, M. J., Azijn, H., Lewi, P. J., & Janssen, P. A. J., et al. (2000). R165335-TMC125, a novel non nucleoside reverse transcriptase inhibitor (NNRTI) with nanomolar activity against NNRTI resistant HIV strains. In Proceedings of the Abstracts of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy (no. 1840). Toronto, Canada, 17-20 September 2000.
-
(2000)
Proceedings of the Abstracts of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy
, Issue.1840
-
-
Andries, K.1
De Béthune, M.-P.2
Kukla, M.J.3
Azijn, H.4
Lewi, P.J.5
Janssen, P.A.J.6
-
2
-
-
13044256383
-
A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
-
Baba M., Nishimura O., Kanzaki N., Okamoto M., Sawada H., Iizawa Y., et al. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proceedings of National Academy of Sciences of United States of America. 96:1999;5698-5703
-
(1999)
Proceedings of National Academy of Sciences of United States of America
, vol.96
, pp. 5698-5703
-
-
Baba, M.1
Nishimura, O.2
Kanzaki, N.3
Okamoto, M.4
Sawada, H.5
Iizawa, Y.6
-
3
-
-
0032870371
-
Inhibition of human immunodeficiency virus type 1 replication in acutely and chronically infected cells by EM2487, a novel substance produced by a Streptomyces species
-
Baba M., Okamoto M., Takeuchi H. Inhibition of human immunodeficiency virus type 1 replication in acutely and chronically infected cells by EM2487, a novel substance produced by a Streptomyces species. Antimicrobial Agents and Chemotherapy. 43:1999;2350-2355
-
(1999)
Antimicrobial Agents and Chemotherapy
, vol.43
, pp. 2350-2355
-
-
Baba, M.1
Okamoto, M.2
Takeuchi, H.3
-
4
-
-
2942563387
-
-
Submitted for publication.
-
Balzarini, J., Hatse, S., Vermeire, K., Princen, K., De Clercq, E., & Egberink, et al. (2003). Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides to prevent infection and transmission of the human immunodeficiency virus, Submitted for publication.
-
(2003)
Mannose-specific Plant Lectins from the Amaryllidaceae Family Qualify As Efficient Microbicides to Prevent Infection and Transmission of the Human Immunodeficiency Virus
-
-
Balzarini, J.1
Hatse, S.2
Vermeire, K.3
Princen, K.4
De Clercq, E.5
Egberink6
-
5
-
-
0032500021
-
Preclinical studies on thiocarboxanilide UC-781 as a virucidal agent
-
Balzarini J., Naesens L., Verbeken E., Laga M., Van Damme L., Parniak M., et al. Preclinical studies on thiocarboxanilide UC-781 as a virucidal agent. Acquired Immunodeficiency Syndrome. 12:1998;1129-1138
-
(1998)
Acquired Immunodeficiency Syndrome
, vol.12
, pp. 1129-1138
-
-
Balzarini, J.1
Naesens, L.2
Verbeken, E.3
Laga, M.4
Van Damme, L.5
Parniak, M.6
-
6
-
-
0038454664
-
Antiretroviral activity of semisynthetic derivatives of glycopeptide antibiotics
-
Balzarini J., Pannecouque C., De Clercq E., Pavlov A.Y., Printsevskaya S.S., Miroshnikova O.V., et al. Antiretroviral activity of semisynthetic derivatives of glycopeptide antibiotics. Journal of Medical Chemistry. 46:2003;2755-2764
-
(2003)
Journal of Medical Chemistry
, vol.46
, pp. 2755-2764
-
-
Balzarini, J.1
Pannecouque, C.2
De Clercq, E.3
Pavlov, A.Y.4
Printsevskaya, S.S.5
Miroshnikova, O.V.6
-
7
-
-
0023026496
-
Potent and selective anti-HTLV-III/LAV activity of 2′,3′- dideoxycytidinene, the 2′,3′-unsaturated derivative of 2′,3′-dideoxycytidine
-
Balzarini J., Pauwels R., Herdewijn P., De Clercq E., Cooney D.A., Kang G.J., et al. Potent and selective anti-HTLV-III/LAV activity of 2′, 3′-dideoxycytidinene, the 2′, 3′-unsaturated derivative of 2′, 3′-dideoxycytidine. Biochemical and Biophysical Research Communication. 140:1986;735-742
-
(1986)
Biochemical and Biophysical Research Communication
, vol.140
, pp. 735-742
-
-
Balzarini, J.1
Pauwels, R.2
Herdewijn, P.3
De Clercq, E.4
Cooney, D.A.5
Kang, G.J.6
-
8
-
-
2942589817
-
-
Submitted for publication.
-
Balzarini, J., Van Laethem, K., Hatse, S., Vermeire, K., De Clercq, E., & Peumans, et al. (2003). Unique resistance profile of human immunodeficiency virus against mannose-specific plant lectins, Submitted for publication.
-
(2003)
Unique Resistance Profile of Human Immunodeficiency Virus Against Mannose-specific Plant Lectins
-
-
Balzarini, J.1
Van Laethem, K.2
Hatse, S.3
Vermeire, K.4
De Clercq, E.5
Peumans6
-
9
-
-
0037426728
-
Tenofovir disoproxil fumarate in patients with HIV and lamivudine-resistant hepatitis B virus
-
Benhamou Y., Tubiana R., Thibault V. Tenofovir disoproxil fumarate in patients with HIV and lamivudine-resistant hepatitis B virus. New English Journal of Medicine. 348:2003;177-178
-
(2003)
New English Journal of Medicine
, vol.348
, pp. 177-178
-
-
Benhamou, Y.1
Tubiana, R.2
Thibault, V.3
-
10
-
-
0030997133
-
Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: Retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase
-
Borkow G., Barnard J., Nguyen T.M., Belmonte A., Wainberg M.A., Parniak M.A. Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: Retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase. Journal of Virology. 71:1997;3023-3030
-
(1997)
Journal of Virology
, vol.71
, pp. 3023-3030
-
-
Borkow, G.1
Barnard, J.2
Nguyen, T.M.3
Belmonte, A.4
Wainberg, M.A.5
Parniak, M.A.6
-
11
-
-
0037300816
-
Cyanovirin-N: A sugar-binding antiviral protein with a new twist
-
Botos I., Wlodawer A. Cyanovirin-N: A sugar-binding antiviral protein with a new twist. Cellular and Molecular Life Science. 60:2003;277-287
-
(2003)
Cellular and Molecular Life Science
, vol.60
, pp. 277-287
-
-
Botos, I.1
Wlodawer, A.2
-
12
-
-
0030790094
-
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: Potential applications to microbicide development
-
Boyd M.R., Gustafson K.R., McMahon J.B., Shoemaker R.H., O'Keefe B.R., Mori T., et al. Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: Potential applications to microbicide development. Antimicrobial Agents and Chemotherapy. 41:1997;1521-1530
-
(1997)
Antimicrobial Agents and Chemotherapy
, vol.41
, pp. 1521-1530
-
-
Boyd, M.R.1
Gustafson, K.R.2
McMahon, J.B.3
Shoemaker, R.H.4
O'Keefe, B.R.5
Mori, T.6
-
13
-
-
0037667047
-
Large-scale manufacture of peptide therapeutics by chemical synthesis
-
Bray B.L. Large-scale manufacture of peptide therapeutics by chemical synthesis. Nature Review and Drug Discovery. 2:2003;587-593
-
(2003)
Nature Review and Drug Discovery
, vol.2
, pp. 587-593
-
-
Bray, B.L.1
-
14
-
-
12244267994
-
Binding of 2-aryl-4-(piperidin-1-yl)butanamines and 1,3,4-trisubstituted pyrrolidines to human CCR5: A molecular modeling-guided mutagenesis study of the binding pocket
-
Castonguay L.A., Weng Y., Adolfsen W., Di Salvo J., Kilburn R., Caldwell C.G., et al. Binding of 2-aryl-4-(piperidin-1-yl)butanamines and 1, 3, 4-trisubstituted pyrrolidines to human CCR5: A molecular modeling-guided mutagenesis study of the binding pocket. Biochemistry. 42:2003;1544-1550
-
(2003)
Biochemistry
, vol.42
, pp. 1544-1550
-
-
Castonguay, L.A.1
Weng, Y.2
Adolfsen, W.3
Di Salvo, J.4
Kilburn, R.5
Caldwell, C.G.6
-
15
-
-
0034665961
-
Flavopiridol inhibits P-TEFb and blocks HIV-1 replication
-
Chao S.H., Fujinaga K., Marion J.E., Taube R., Sausville E.A., Senderowicz A.M., et al. Flavopiridol inhibits P-TEFb and blocks HIV-1 replication. Journal of Biological Chemistry. 275:2000;28345-28348
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 28345-28348
-
-
Chao, S.H.1
Fujinaga, K.2
Marion, J.E.3
Taube, R.4
Sausville, E.A.5
Senderowicz, A.M.6
-
16
-
-
0036753540
-
Tat stimulates cotranscriptional capping of HIV mRNA
-
Chiu Y.L., Ho C.K., Saha N., Schwer B., Shuman S., Rana T.M. Tat stimulates cotranscriptional capping of HIV mRNA. Molecular Cell. 10:2002;585-597
-
(2002)
Molecular Cell
, vol.10
, pp. 585-597
-
-
Chiu, Y.L.1
Ho, C.K.2
Saha, N.3
Schwer, B.4
Shuman, S.5
Rana, T.M.6
-
17
-
-
0037379517
-
Activities of atazanavir (BMS-232632) against a large panel of human immunodeficiency virus type 1 clinical isolates resistant to one or more approved protease inhibitors
-
Colonno R.J., Thiry A., Limoli K., Parkin N. Activities of atazanavir (BMS-232632) against a large panel of human immunodeficiency virus type 1 clinical isolates resistant to one or more approved protease inhibitors. Antimicrobial Agents and Chemotherapy. 47:2003;1324-1333
-
(2003)
Antimicrobial Agents and Chemotherapy
, vol.47
, pp. 1324-1333
-
-
Colonno, R.J.1
Thiry, A.2
Limoli, K.3
Parkin, N.4
-
18
-
-
0032786364
-
Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1
-
Corbett J.W., Ko S.S., Rodgers J.D., Jeffrey S., Bacheler L.T., Klabe R.M., et al. Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapy. 43:1999;2893-2897
-
(1999)
Antimicrobial Agents and Chemotherapy
, vol.43
, pp. 2893-2897
-
-
Corbett, J.W.1
Ko, S.S.2
Rodgers, J.D.3
Jeffrey, S.4
Bacheler, L.T.5
Klabe, R.M.6
-
19
-
-
0034128898
-
Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors
-
Corbett J.W., Ko S.S., Rodgers J.D., Gearhart L.A., Magnus N.A., Bacheler L.T., et al. Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors. Journal of Medical Chemistry. 43:2000;2019-2030
-
(2000)
Journal of Medical Chemistry
, vol.43
, pp. 2019-2030
-
-
Corbett, J.W.1
Ko, S.S.2
Rodgers, J.D.3
Gearhart, L.A.4
Magnus, N.A.5
Bacheler, L.T.6
-
20
-
-
0031439586
-
S-Adenosylhomocysteine hydrolase inhibitors interfere with the replication of human immunodeficiency virus type 1 through inhibition of the LTR transactivation
-
Daelemans D., Esté J.A., Witvrouw M., Pannecouque C., Jonckheere H., Aquaro S., et al. S-Adenosylhomocysteine hydrolase inhibitors interfere with the replication of human immunodeficiency virus type 1 through inhibition of the LTR transactivation. Molecular Pharmacology. 52:1997;1157-1163
-
(1997)
Molecular Pharmacology
, vol.52
, pp. 1157-1163
-
-
Daelemans, D.1
Esté, J.A.2
Witvrouw, M.3
Pannecouque, C.4
Jonckheere, H.5
Aquaro, S.6
-
21
-
-
0033971512
-
A second target for the peptoid Tat/transactivation response element inhibitor CGP64222: Inhibition of human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry
-
Daelemans D., Schols D., Witvrouw M., Pannecouque C., Hatse S., van Dooren S., et al. A second target for the peptoid Tat/transactivation response element inhibitor CGP64222: Inhibition of human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry. Molecular Pharmacology. 57:2000;116-124
-
(2000)
Molecular Pharmacology
, vol.57
, pp. 116-124
-
-
Daelemans, D.1
Schols, D.2
Witvrouw, M.3
Pannecouque, C.4
Hatse, S.5
Van Dooren, S.6
-
22
-
-
0037195181
-
A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export
-
Daelemans D., Afonina E., Nilsson J., Werner G., Kjems J., De Clercq E., et al. A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export. Proceedings of National Academy of United States of America. 99:2002;14440-14445
-
(2002)
Proceedings of National Academy of United States of America
, vol.99
, pp. 14440-14445
-
-
Daelemans, D.1
Afonina, E.2
Nilsson, J.3
Werner, G.4
Kjems, J.5
De Clercq, E.6
-
24
-
-
0041488800
-
Small-molecule HIV-1 integrase inhibitors: The 2001-2002 update
-
Dayam R., Neamati N. Small-molecule HIV-1 integrase inhibitors: The 2001-2002 update. Current Pharmaceutical Design. 9:2003;1789-1902
-
(2003)
Current Pharmaceutical Design
, vol.9
, pp. 1789-1902
-
-
Dayam, R.1
Neamati, N.2
-
25
-
-
0013409604
-
TMC 114, a highly potent protease inhibitor (PI) with an excellent profile against HIV variants highly resistant to current Pis
-
Chicago, IL, USA, 16-19 December 2001, Abstracts F-1677.
-
de Béthune, M., Wigerinck, P., Jonckheere, H., Tahri, A., Maes, L., & Pauwels, R., et al. (2001). TMC 114, a highly potent protease inhibitor (PI) with an excellent profile against HIV variants highly resistant to current Pis. In Proceedings of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). Chicago, IL, USA, 16-19 December 2001, Abstracts F-1677.
-
(2001)
Proceedings of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
-
-
De Béthune, M.1
Wigerinck, P.2
Jonckheere, H.3
Tahri, A.4
Maes, L.5
Pauwels, R.6
-
26
-
-
0032437454
-
The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection
-
De Clercq E. The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection. Antiviral Research. 38:1998;153-179
-
(1998)
Antiviral Research
, vol.38
, pp. 153-179
-
-
De Clercq, E.1
-
29
-
-
2342451795
-
Potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections
-
De Clercq E. Potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections. Expert Review Anti-infection Therapy. 1:2003;21-43
-
(2003)
Expert Review Anti-infection Therapy
, vol.1
, pp. 21-43
-
-
De Clercq, E.1
-
30
-
-
0034625144
-
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
-
Dragic T., Trkola A., Thompson D.A., Cormier E.G., Kajumo F.A., Maxwell E., et al. A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5. Proceedings of National Academy of United States of America. 97:2000;5639-5644
-
(2000)
Proceedings of National Academy of United States of America
, vol.97
, pp. 5639-5644
-
-
Dragic, T.1
Trkola, A.2
Thompson, D.A.3
Cormier, E.G.4
Kajumo, F.A.5
Maxwell, E.6
-
31
-
-
0037542551
-
Once-a-day highly active antiretroviral therapy: A systemic review
-
Ena J., Pasquau F. Once-a-day highly active antiretroviral therapy: A systemic review. Clinical Infection and Disease. 36:2003;1186-1190
-
(2003)
Clinical Infection and Disease
, vol.36
, pp. 1186-1190
-
-
Ena, J.1
Pasquau, F.2
-
32
-
-
12444267896
-
Cellular pharmacology of D-d4FC, a nucleoside analogue active against drug-resistant HIV
-
Erickson-Viitanen S., Wu J.-T., Shi G., Unger S., King R.W., Fish B., et al. Cellular pharmacology of D-d4FC, a nucleoside analogue active against drug-resistant HIV. Antiviral Chemistry and Chemotherapy. 14(14):2003;39-47
-
(2003)
Antiviral Chemistry and Chemotherapy
, vol.14
, Issue.14
, pp. 39-47
-
-
Erickson-Viitanen, S.1
Wu, J.-T.2
Shi, G.3
Unger, S.4
King, R.W.5
Fish, B.6
-
33
-
-
10744226580
-
Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations
-
Fikkert V., Van Maele B., Vercammen J., Hantson A., Van Remoortel B., Michiels M., et al. Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations. Journal of Virology. 77:2003;11459-11470
-
(2003)
Journal of Virology
, vol.77
, pp. 11459-11470
-
-
Fikkert, V.1
Van Maele, B.2
Vercammen, J.3
Hantson, A.4
Van Remoortel, B.5
Michiels, M.6
-
34
-
-
0035162759
-
Mechanism of action of 1-β-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-β-D-dioxolane guanosine
-
Furman P.A., Jeffrey J., Kiefer L.L., Feng J.Y., Anderson K.S., Borroto-Esoda K., et al. Mechanism of action of 1-β-D-2, 6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-β-D-dioxolane guanosine. Antimicrobial Agents and Chemotherapy. 45:2001;158-165
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, pp. 158-165
-
-
Furman, P.A.1
Jeffrey, J.2
Kiefer, L.L.3
Feng, J.Y.4
Anderson, K.S.5
Borroto-Esoda, K.6
-
35
-
-
0011343037
-
TMC125, a next-generation NNRTI, demonstrates high potency after 7 days therapy in treatment-experienced HIV-1-infected individuals with phenotypic NNRTI resistance
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Gazzard, B., Pozniak, A., Arasteh, K., Staszewski, S., Rozenbaum, W., & Yeni, P., et al. (2002). TMC125, a next-generation NNRTI, demonstrates high potency after 7 days therapy in treatment-experienced HIV-1-infected individuals with phenotypic NNRTI resistance. In: Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections (no. 4, p. 54). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
(2002)
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
, Issue.4
, pp. 54
-
-
Gazzard, B.1
Pozniak, A.2
Arasteh, K.3
Staszewski, S.4
Rozenbaum, W.5
Yeni, P.6
-
36
-
-
12444325183
-
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor β-D-2′, 3′-dideoxy-2′, 3′-didehydro-5- fluorocytidine (Reverset™)
-
Geleziunas R., Gallagher K., Zhang H., Bacheler L., Garber S., Wu J.-T., et al. HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor β-D-2′, 3′-dideoxy-2′, 3′-didehydro-5- fluorocytidine (Reverset™). Antiviral Chemistry and Chemotherapy. 14:2003;49-59
-
(2003)
Antiviral Chemistry and Chemotherapy
, vol.14
, pp. 49-59
-
-
Geleziunas, R.1
Gallagher, K.2
Zhang, H.3
Bacheler, L.4
Garber, S.5
Wu, J.-T.6
-
37
-
-
13044295993
-
Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drug design
-
Goldgur Y., Craigie R., Cohen G.H., Fujiwara T., Yoshinaga T., Fujishita T., et al. Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drug design. Proceedings of National Academy of United States of America. 96:1999;13040-13043
-
(1999)
Proceedings of National Academy of United States of America
, vol.96
, pp. 13040-13043
-
-
Goldgur, Y.1
Craigie, R.2
Cohen, G.H.3
Fujiwara, T.4
Yoshinaga, T.5
Fujishita, T.6
-
38
-
-
0033844808
-
In vitro resistance profile of the human immunodeficiency virus type 1 protease inhibitor BMS-232632
-
Gong Y.F., Robinson B.S., Rose R.E., Deminie C., Spicer T.P., Stock D., et al. In vitro resistance profile of the human immunodeficiency virus type 1 protease inhibitor BMS-232632. Antimicrobial Agents and Chemotherapy. 44:2000;2319-2326
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, pp. 2319-2326
-
-
Gong, Y.F.1
Robinson, B.S.2
Rose, R.E.3
Deminie, C.4
Spicer, T.P.5
Stock, D.6
-
39
-
-
0037076324
-
Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes
-
Grobler J.A., Stillmock K., Hu B., Witmer M., Felock P., Espeseth A.S., et al. Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes. Proceedings of National Academy of United States of America. 99:2002;6661-6666
-
(2002)
Proceedings of National Academy of United States of America
, vol.99
, pp. 6661-6666
-
-
Grobler, J.A.1
Stillmock, K.2
Hu, B.3
Witmer, M.4
Felock, P.5
Espeseth, A.S.6
-
40
-
-
0037661234
-
Therapy with atazanavir plus saquinavir in patients failing highly active antretroviral therapy: A randomized comparative pilot trial
-
Haas D.W., Zala C., Schrader S., Piliero P., Jaeger H., Nunes D., et al. Therapy with atazanavir plus saquinavir in patients failing highly active antretroviral therapy: A randomized comparative pilot trial. Acquired Immunodeficiency Syndrome. 17:2003;1339-1349
-
(2003)
Acquired Immunodeficiency Syndrome
, vol.17
, pp. 1339-1349
-
-
Haas, D.W.1
Zala, C.2
Schrader, S.3
Piliero, P.4
Jaeger, H.5
Nunes, D.6
-
41
-
-
0035935205
-
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 2. Lead optimization affording selective % orally bioavailable compounds with potent anti-HIV activity
-
Hale J.J., Budhu R.J., Holson E.B., Finke P.E., Oates B., Mills S.G., et al. 1, 3, 4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 2. Lead optimization affording selective % orally bioavailable compounds with potent anti-HIV activity. Bioorganic Medical Chemistry and Letters. 11:2001;2741-2745
-
(2001)
Bioorganic Medical Chemistry and Letters
, vol.11
, pp. 2741-2745
-
-
Hale, J.J.1
Budhu, R.J.2
Holson, E.B.3
Finke, P.E.4
Oates, B.5
Mills, S.G.6
-
42
-
-
18644374488
-
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 3. Polar functionality and its effect on anti-HIV-1 activity
-
Hale J.J., Budhu R.J., Mills S.G., MacCoss M., Gould S.L., DeMartino J.A., et al. 1, 3, 4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 3. Polar functionality and its effect on anti-HIV-1 activity. Bioorganic Medical Chemistry and Letters. 12:2002;2997-3000
-
(2002)
Bioorganic Medical Chemistry and Letters
, vol.12
, pp. 2997-3000
-
-
Hale, J.J.1
Budhu, R.J.2
Mills, S.G.3
MacCoss, M.4
Gould, S.L.5
Demartino, J.A.6
-
43
-
-
0030976612
-
An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication
-
Hamy F., Felder E.R., Heizmann G., Lazdins J., Aboul-ela F., Varani G., et al. An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication. Proceedings of the National Academy of Sciences of United States of America. 94:1997;3548-3553
-
(1997)
Proceedings of the National Academy of Sciences of United States of America
, vol.94
, pp. 3548-3553
-
-
Hamy, F.1
Felder, E.R.2
Heizmann, G.3
Lazdins, J.4
Aboul-Ela, F.5
Varani, G.6
-
44
-
-
0037340618
-
Relative anti-HIV-1 efficacy of lamivudine and emtricitabine in vitro is dependent on cell type
-
Hazen R., Lanier E.R. Relative anti-HIV-1 efficacy of lamivudine and emtricitabine in vitro is dependent on cell type. Journal of Acquired Immune Deficiency Syndrome. 32:2003;255-258
-
(2003)
Journal of Acquired Immune Deficiency Syndrome
, vol.32
, pp. 255-258
-
-
Hazen, R.1
Lanier, E.R.2
-
45
-
-
0034723439
-
Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
-
Hazuda D.J., Felock P., Witmer M., Wolfe A., Stillmock K., Grobler J.A., et al. Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells. Science. 287:2000;646-650
-
(2000)
Science
, vol.287
, pp. 646-650
-
-
Hazuda, D.J.1
Felock, P.2
Witmer, M.3
Wolfe, A.4
Stillmock, K.5
Grobler, J.A.6
-
46
-
-
1542372469
-
Analysis of patient-derived HIV-1 isolates suggests a novel mechanism for decreased sensitivity to inhibition by enfuvirtide and T-649
-
Boston, MA, USA, 10-14 February 2003, Abstracts.
-
Heil, M., Decker, J., Chen, D.- T., Sfakianos, J., Shaw, G., & Hunter, E., et al. (2003). Analysis of patient-derived HIV-1 isolates suggests a novel mechanism for decreased sensitivity to inhibition by enfuvirtide and T-649. In Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections (no. 615). Boston, MA, USA, 10-14 February 2003, Abstracts.
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
, Issue.615
-
-
Heil, M.1
Decker, J.2
Chen, D.-T.3
Sfakianos, J.4
Shaw, G.5
Hunter, E.6
-
47
-
-
0034120373
-
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR4-chemokine receptor, in human volunteers
-
Hendrix C.W., Flexner C., MacFarland R.T., Giandomenico C., Fuchs E.J., Redpath E., et al. Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR4-chemokine receptor, in human volunteers. Antimicrobial Agents and Chemotherapy. 44:2000;1667-1673
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, pp. 1667-1673
-
-
Hendrix, C.W.1
Flexner, C.2
MacFarland, R.T.3
Giandomenico, C.4
Fuchs, E.J.5
Redpath, E.6
-
48
-
-
0037388121
-
A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity
-
Ichiyama K., Yokoyama-Kumakura S., Tanaka Y., Tanaka R., Hirose K., Bannai K., et al. A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity. Proceedings of National Academy of United States of America. 100:2003;4185-4190
-
(2003)
Proceedings of National Academy of United States of America
, vol.100
, pp. 4185-4190
-
-
Ichiyama, K.1
Yokoyama-Kumakura, S.2
Tanaka, Y.3
Tanaka, R.4
Hirose, K.5
Bannai, K.6
-
49
-
-
0041392874
-
Anti-HIV-1 activity of TAK-220, a small molecule CCR5 antagonist
-
Boston, MA, USA, 10-14 February 2003, Abstracts.
-
Iizawa, Y., Kanzaki, N., Takashima, K., Miyake, H., Tagawa, Y., & Sugihara, Y., et al. (2003). Anti-HIV-1 activity of TAK-220, a small molecule CCR5 antagonist. In Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections (no. 11). Boston, MA, USA, 10-14 February 2003, Abstracts.
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
, Issue.11
-
-
Iizawa, Y.1
Kanzaki, N.2
Takashima, K.3
Miyake, H.4
Tagawa, Y.5
Sugihara, Y.6
-
50
-
-
0038143190
-
Dioxolane guanosine 5′-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase
-
Jeffrey J.L., Feng J.Y., Qi C.C.R., Anderson K.S., Furman P.A. Dioxolane guanosine 5′-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Journal of Biological Chemistry. 278:2003;18971-18979
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 18971-18979
-
-
Jeffrey, J.L.1
Feng, J.Y.2
Qi, C.C.R.3
Anderson, K.S.4
Furman, P.A.5
-
51
-
-
14944368002
-
Atazanavir and efavirenz, each combined with fixed-dose zidovudine and lamivudine, have similar effects on body fat distribution in antiretroviral-naïve patients: 48-week results from the metabolic substudy of BMS AI424-034
-
Paris, France, 14-17 July 2003, Abstracts.
-
Jemsek, J. G., Arathoon, E., Arlotti, M., Perez, C., Sosa, N., & Giordano, M., et al. (2003). Atazanavir and efavirenz, each combined with fixed-dose zidovudine and lamivudine, have similar effects on body fat distribution in antiretroviral-naïve patients: 48-week results from the metabolic substudy of BMS AI424-034. In Proceedings of the 2nd IAS Conference on HIV and Pathogenesis. Paris, France, 14-17 July 2003, Abstracts.
-
(2003)
Proceedings of the 2nd IAS Conference on HIV and Pathogenesis
-
-
Jemsek, J.G.1
Arathoon, E.2
Arlotti, M.3
Perez, C.4
Sosa, N.5
Giordano, M.6
-
52
-
-
0242705329
-
Enfuvirtide TORO studies: 48 Week results confirm 24 week findings
-
Paris, France, 14-17 July 2003, Abstracts.
-
Katlama, C., Arastéh, K., Clotet, B., Cooper, D., Henry, K., & Lalezari, J., et al. (2003). Enfuvirtide TORO studies: 48 week results confirm 24 week findings. In Proceedings of the 2nd IAS Conference on HIV and Pathogenesis. Paris, France, 14-17 July 2003, Abstracts.
-
(2003)
Proceedings of the 2nd IAS Conference on HIV and Pathogenesis
-
-
Katlama, C.1
Arastéh, K.2
Clotet, B.3
Cooper, D.4
Henry, K.5
Lalezari, J.6
-
53
-
-
0345700287
-
Entry inhibitors SCH-C, RANTES, and T-20 block HIV type 1 replication in multiple cell types
-
Ketas T.J., Klasse P.J., Spenlehauer C., Nesin M., Frank I., Pope M., et al. Entry inhibitors SCH-C, RANTES, and T-20 block HIV type 1 replication in multiple cell types. Acquired Immunodeficiency Syndrome Res. Hum. Retrovir. 19:2003;177-186
-
(2003)
Acquired Immunodeficiency Syndrome Res. Hum. Retrovir.
, vol.19
, pp. 177-186
-
-
Ketas, T.J.1
Klasse, P.J.2
Spenlehauer, C.3
Nesin, M.4
Frank, I.5
Pope, M.6
-
54
-
-
12244301646
-
Enzymatic assay for measurement of intracellular DXG triphosphate concentrations in peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected patients
-
Kewn S., Wang L.H., Hoggard P.G., Rousseau F., Hart R., MacNeela J.P., et al. Enzymatic assay for measurement of intracellular DXG triphosphate concentrations in peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected patients. Antimicrobial Agents and Chemotherapy. 47:2003;255-261
-
(2003)
Antimicrobial Agents and Chemotherapy
, vol.47
, pp. 255-261
-
-
Kewn, S.1
Wang, L.H.2
Hoggard, P.G.3
Rousseau, F.4
Hart, R.5
MacNeela, J.P.6
-
55
-
-
0031729823
-
Potent suppression of HIV-1 replication in humans by T-20% a peptide inhibitor of gp41-mediated virus entry
-
Kilby J.M., Hopkins S., Venetta S.M., DiMassimo B., Cloud G.A., Lee J.Y., et al. Potent suppression of HIV-1 replication in humans by T-20% a peptide inhibitor of gp41-mediated virus entry. Natural Medicine. 4:1998;1302-1307
-
(1998)
Natural Medicine
, vol.4
, pp. 1302-1307
-
-
Kilby, J.M.1
Hopkins, S.2
Venetta, S.M.3
Dimassimo, B.4
Cloud, G.A.5
Lee, J.Y.6
-
56
-
-
0031685017
-
Resistance to the anti-human immunodeficiency virus type 1 compound L-chicoric acid results from a single mutation at amino acid 140 of integrase
-
King P.J., Robinson W.E. Jr. Resistance to the anti-human immunodeficiency virus type 1 compound L-chicoric acid results from a single mutation at amino acid 140 of integrase. Journal of Virology. 72:1998;8420-8424
-
(1998)
Journal of Virology
, vol.72
, pp. 8420-8424
-
-
King, P.J.1
Robinson Jr., W.E.2
-
57
-
-
0037293099
-
Human immunodeficiency virus type-1 integrase containing a glycine to serine mutation at position 140 is attenuated for catalysis and resistant to integrase inhibitors
-
King P.J., Lee D.J., Reinke R.A., Victoria J.G., Beale K., Robinson W.E. Human immunodeficiency virus type-1 integrase containing a glycine to serine mutation at position 140 is attenuated for catalysis and resistant to integrase inhibitors. Virology. 306:2003;147-161
-
(2003)
Virology
, vol.306
, pp. 147-161
-
-
King, P.J.1
Lee, D.J.2
Reinke, R.A.3
Victoria, J.G.4
Beale, K.5
Robinson, W.E.6
-
58
-
-
0036338304
-
1,2,4-Triazole derivatives inhibiting the human immunodeficiency virus type 1 (HIV-1) in vitro
-
Lagoja I.M., Pannecouque C., Musumeci L., Froeyen M., Van Aerschot A., Balzarini J., et al. 1, 2, 4-Triazole derivatives inhibiting the human immunodeficiency virus type 1 (HIV-1) in vitro. Helves Chimica Acta. 85:2002;1883-1892
-
(2002)
Helves Chimica Acta
, vol.85
, pp. 1883-1892
-
-
Lagoja, I.M.1
Pannecouque, C.2
Musumeci, L.3
Froeyen, M.4
Van Aerschot, A.5
Balzarini, J.6
-
59
-
-
0242500883
-
N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action
-
Lagoja I.M., Pannecouque C., Van Aerschot A., Witvrouw M., Debyser Z., Balzarini J., et al. N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action. Journal of Medical Chemistry. 46:2003;1546-1553
-
(2003)
Journal of Medical Chemistry
, vol.46
, pp. 1546-1553
-
-
Lagoja, I.M.1
Pannecouque, C.2
Van Aerschot, A.3
Witvrouw, M.4
Debyser, Z.5
Balzarini, J.6
-
60
-
-
0038576281
-
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
-
Lalezari J.P., Henry K., O'Hearn M., Montaner J.S.G., Piliero P.J., Trottier B., et al. Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. New English Journal of Medicine. 348:2003;2175-2185
-
(2003)
New English Journal of Medicine
, vol.348
, pp. 2175-2185
-
-
Lalezari, J.P.1
Henry, K.2
O'Hearn, M.3
Montaner, J.S.G.4
Piliero, P.J.5
Trottier, B.6
-
61
-
-
0034623020
-
Tipranavir inhibits broadly protease inhibitor-resistant HIV-1 clinical samples
-
Larder B.A., Hertogs K., Bloor S., van den Eynde C.H., DeCian W., Wang Y., et al. Tipranavir inhibits broadly protease inhibitor-resistant HIV-1 clinical samples. Acquired Immunodeficiency Syndrome. 14:2000;1943-1948
-
(2000)
Acquired Immunodeficiency Syndrome
, vol.14
, pp. 1943-1948
-
-
Larder, B.A.1
Hertogs, K.2
Bloor, S.3
Van Den Eynde, C.H.4
Decian, W.5
Wang, Y.6
-
62
-
-
0037849954
-
Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia
-
Lazzarin A., Clotet B., Cooper D., Reynes J., Arastéh K., Nelson M., et al. Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia. New English Journal of Medicine. 348:2003;2186-2195
-
(2003)
New English Journal of Medicine
, vol.348
, pp. 2186-2195
-
-
Lazzarin, A.1
Clotet, B.2
Cooper, D.3
Reynes, J.4
Arastéh, K.5
Nelson, M.6
-
63
-
-
0037530011
-
Determining the antiviral activity of tenofovir disoproxil fumarate in treatment-naïve chronically HIV-1-infected individuals
-
Louie M., Hogan C., Hurley A., Simon V., Chung C., Padte N., et al. Determining the antiviral activity of tenofovir disoproxil fumarate in treatment-naïve chronically HIV-1-infected individuals. Acquired Immunodeficiency Syndrome. 17:2003;1151-1156
-
(2003)
Acquired Immunodeficiency Syndrome
, vol.17
, pp. 1151-1156
-
-
Louie, M.1
Hogan, C.2
Hurley, A.3
Simon, V.4
Chung, C.5
Padte, N.6
-
64
-
-
0037444053
-
Determining the relative efficacy of highly active antiretroviral therapy
-
Louie M., Hogan C., Di Mascio M., Hurley A., Simon V., Rooney J., et al. Determining the relative efficacy of highly active antiretroviral therapy. Journal of Infection and Disease. 187:2003;896-900
-
(2003)
Journal of Infection and Disease
, vol.187
, pp. 896-900
-
-
Louie, M.1
Hogan, C.2
Di Mascio, M.3
Hurley, A.4
Simon, V.5
Rooney, J.6
-
65
-
-
18244396143
-
CCR5 antagonists: Bicyclic isoxazolidines as conformationally constrained N-1-substituted pyrrolidines
-
Lynch C.L., Gentry A.L., Hale J.J., Mills S.G., MacCoss M., Malkowitz L., et al. CCR5 antagonists: Bicyclic isoxazolidines as conformationally constrained N-1-substituted pyrrolidines. Bioorganic Medical Chemistry and Letters. 12:2002;677-679
-
(2002)
Bioorganic Medical Chemistry and Letters
, vol.12
, pp. 677-679
-
-
Lynch, C.L.1
Gentry, A.L.2
Hale, J.J.3
Mills, S.G.4
MacCoss, M.5
Malkowitz, L.6
-
66
-
-
18644372005
-
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 4. Synthesis of N-1-acidic functionality affording analogues with enhanced antiviral activity against HIV
-
Lynch C.L., Hale J.J., Budhu R.J., Gentry A.L., Mills S.G., Chapman K.T., et al. 1, 3, 4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 4. Synthesis of N-1-acidic functionality affording analogues with enhanced antiviral activity against HIV. Bioorganic Medical Chemistry and Letters. 12:2002;3001-3004
-
(2002)
Bioorganic Medical Chemistry and Letters
, vol.12
, pp. 3001-3004
-
-
Lynch, C.L.1
Hale, J.J.2
Budhu, R.J.3
Gentry, A.L.4
Mills, S.G.5
Chapman, K.T.6
-
67
-
-
0035860744
-
Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5
-
Maeda K., Yoshimura K., Shibayama S., Habashita H., Tada H., Sagawa K., et al. Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5. Journal of Biological Chemistry. 276:2001;35194-35200
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 35194-35200
-
-
Maeda, K.1
Yoshimura, K.2
Shibayama, S.3
Habashita, H.4
Tada, H.5
Sagawa, K.6
-
68
-
-
2942597091
-
Novel HIV-specific spirodiketopiperazine CCR5 inhibitors potent against a wide spectrum of R5-HIV, HIV DART 2002. Frontiers in drug development for antiretroviral therapies (no. 014)
-
Naples, FL, USA, 15-19 December 2002; 2002, Abstracts.
-
Maeda, K., Nakata, H., Miyakawa, T., Ogata, H., Koh, Y., & Takaoka, Y., et al. (2002). Novel HIV-specific spirodiketopiperazine CCR5 inhibitors potent against a wide spectrum of R5-HIV, HIV DART 2002. Frontiers in drug development for antiretroviral therapies (no. 014). Naples, FL, USA, 15-19 December 2002; Antiviral Research, 2002, Abstracts.
-
(2002)
Antiviral Research
-
-
Maeda, K.1
Nakata, H.2
Miyakawa, T.3
Ogata, H.4
Koh, Y.5
Takaoka, Y.6
-
69
-
-
11244317278
-
Long-term tenofovir treatment of lamivudine-resistant chronic hepatitis B in HIV co-infected patients
-
Boston, MA, USA, 10-14 February 2003, Abstracts.
-
Marcelin, A. G., Tubiana, R., Benhamou, Y., Katlama, C., Calvez, V., & Thibault, V. (2003). Long-term tenofovir treatment of lamivudine-resistant chronic hepatitis B in HIV co-infected patients. In Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections (no. 824). Boston, MA, USA, 10-14 February 2003, Abstracts.
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
, Issue.824
-
-
Marcelin, A.G.1
Tubiana, R.2
Benhamou, Y.3
Katlama, C.4
Calvez, V.5
Thibault, V.6
-
70
-
-
0038372726
-
Extended treatment with tenofovir disoproxil fumarate in treatment-experienced HIV-1-infected patients: Genotypic, phenotypic, and rebound analyses
-
Margot N.A., Isaacson E., McGowan I., Cheng A., Miller M.D. Extended treatment with tenofovir disoproxil fumarate in treatment-experienced HIV-1-infected patients: Genotypic, phenotypic, and rebound analyses. Journal of Acquired Immune Deficiency Syndrome. 33:2003;15-21
-
(2003)
Journal of Acquired Immune Deficiency Syndrome
, vol.33
, pp. 15-21
-
-
Margot, N.A.1
Isaacson, E.2
McGowan, I.3
Cheng, A.4
Miller, M.D.5
-
71
-
-
0038394467
-
An open-label steady state investigation of the pharmacokinetics (PK) of tipranavir (TPV) and ritonavir (RTV) and their effects on cytochrome P-450 (3A4) activity in normal health volunteers (BI 1182.5)
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
McCallister, S., Sabo, J., Galitz, L., & Mayers, D. (2002). An open-label steady state investigation of the pharmacokinetics (PK) of tipranavir (TPV) and ritonavir (RTV) and their effects on cytochrome P-450 (3A4) activity in normal health volunteers (BI 1182.5). In Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections (no. 434-W). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
(2002)
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
, Issue.434 W
-
-
McCallister, S.1
Sabo, J.2
Galitz, L.3
Mayers, D.4
-
72
-
-
0036156325
-
Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails
-
Mewshaw J.P., Myrick F.T., Wakefield D.A.C.S., Hooper B.J., Harris J.L., McCreedy B., et al. Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails. Journal of Acquired Immune Deficiency Syndrome. 29:2002;11-20
-
(2002)
Journal of Acquired Immune Deficiency Syndrome
, vol.29
, pp. 11-20
-
-
Mewshaw, J.P.1
Myrick, F.T.2
Wakefield, D.A.C.S.3
Hooper, B.J.4
Harris, J.L.5
McCreedy, B.6
-
73
-
-
0033847883
-
Once-daily combination therapy with emtricitabine, didanosine, and efavirenz in human immunodeficiency virus-infected patients
-
Molina J.M., Ferchal F., Rancinan C., Raffi F., Rozenbaum W., Sereni D., et al. Once-daily combination therapy with emtricitabine, didanosine, and efavirenz in human immunodeficiency virus-infected patients. Journal of Infection and Disease. 182:2000;599-602
-
(2000)
Journal of Infection and Disease
, vol.182
, pp. 599-602
-
-
Molina, J.M.1
Ferchal, F.2
Rancinan, C.3
Raffi, F.4
Rozenbaum, W.5
Sereni, D.6
-
74
-
-
1642357851
-
Analysis of virological response of enfuvirtide in TORO: Implications for patient management
-
Paris, France, 14-17 July 2003, Abstracts.
-
Montaner, J., DeMasi, R., Delehanty, J., Chung, J., Gafoor, Z., & Salgo, M. (2003). Analysis of virological response of enfuvirtide in TORO: Implications for patient management. In Proceedings of the 2nd IAS Conference on HIV and Pathogenesis. Paris, France, 14-17 July 2003, Abstracts.
-
(2003)
Proceedings of the 2nd IAS Conference on HIV and Pathogenesis
-
-
Montaner, J.1
DeMasi, R.2
Delehanty, J.3
Chung, J.4
Gafoor, Z.5
Salgo, M.6
-
75
-
-
0035112229
-
Cyanovirin-N, a potent human immunodeficiency virus-inactivating protein, blocks both CD4-dependent and CD4-independent binding of soluble gp120 (sgp120) to target cells, inhibits sCD4-induced binding of sgp120 to cell-associated CXCR4, and dissociates bound sgp120 from target cells
-
Mori T., Boyd M.R. Cyanovirin-N, a potent human immunodeficiency virus-inactivating protein, blocks both CD4-dependent and CD4-independent binding of soluble gp120 (sgp120) to target cells, inhibits sCD4-induced binding of sgp120 to cell-associated CXCR4, and dissociates bound sgp120 from target cells. Antimicrobial Agents and Chemotherapy. 45:2001;664-672
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, pp. 664-672
-
-
Mori, T.1
Boyd, M.R.2
-
76
-
-
2942584459
-
Pharmacokinetics and safety of the nucleoside reverset in HIV-1 infected patients, HIV DART 2002. Frontiers in drug development for antiretroviral therapies (no. 074)
-
Naples, FL, USA, 15-19 December 2002; 2002, Abstracts.
-
Murphy, R. L., Schürmann, D., Kravec, I., Eron, J., Havlir, D., & Beard, A., et al. (2002). Pharmacokinetics and safety of the nucleoside reverset in HIV-1 infected patients, HIV DART 2002. Frontiers in drug development for antiretroviral therapies (no. 074). Naples, FL, USA, 15-19 December 2002; Antiviral Research, 2002, Abstracts.
-
(2002)
Antiviral Research
-
-
Murphy, R.L.1
Schürmann, D.2
Kravec, I.3
Eron, J.4
Havlir, D.5
Beard, A.6
-
77
-
-
0037159877
-
Activity of tenofovir on hepatitis B virus replication in HIV-co-infected patients failing or partially responding to lamivudine
-
Nunez M., Pérez-Olmeda M., Diaz B., Rios P., Gonzalez-Lahoz J., Soriano V. Activity of tenofovir on hepatitis B virus replication in HIV-co-infected patients failing or partially responding to lamivudine. Acquired Immunodeficiency Syndrome. 16:2002;2352-2354
-
(2002)
Acquired Immunodeficiency Syndrome
, vol.16
, pp. 2352-2354
-
-
Nunez, M.1
Pérez-Olmeda, M.2
Diaz, B.3
Rios, P.4
Gonzalez-Lahoz, J.5
Soriano, V.6
-
78
-
-
0034608946
-
Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37
-
Okamoto H., Cujec T.P., Okamoto M., Peterlin B.M., Baba M., Okamoto T. Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37. Virology. 272:2000;402-408
-
(2000)
Virology
, vol.272
, pp. 402-408
-
-
Okamoto, H.1
Cujec, T.P.2
Okamoto, M.3
Peterlin, B.M.4
Baba, M.5
Okamoto, T.6
-
79
-
-
2942535477
-
® in male volunteers, HIV DART 2002. Frontiers in drug development for antiretroviral therapies (no. 044)
-
Naples, FL, USA, 15-19 December 2002; 2002, Abstracts.
-
® in male volunteers, HIV DART 2002. Frontiers in drug development for antiretroviral therapies (no. 044). Naples, FL, USA, 15-19 December 2002; Antiviral Research, 2002, Abstracts.
-
(2002)
Antiviral Research
-
-
Otto, M.J.1
Arastèh, K.2
Schulbin, H.3
Beard, A.4
Cartee, L.5
Liotta, D.C.6
-
80
-
-
0011263710
-
Anabolic profile of the dioxolane nucleoside analogue DXG in human PBMC; Reversal of resistance by boosting 5′-triphosphate levels
-
Proceedings of the Fifteenth International Conference on Antiviral Research (no. 7). Prague, Czech Republic, 17-21 March 2002;
-
Painter, G. R., St. Claire, R., Feng, J., & Borroto-Esoda, K. (2002). Anabolic profile of the dioxolane nucleoside analogue DXG in human PBMC; reversal of resistance by boosting 5′-triphosphate levels. In Proceedings of the Fifteenth International Conference on Antiviral Research (no. 7). Prague, Czech Republic, 17-21 March 2002; Antiviral Research 53, A37.
-
(2002)
Antiviral Research
, vol.53
-
-
Painter, G.R.1
St Claire, R.2
Feng, J.3
Borroto-Esoda, K.4
-
81
-
-
0037294907
-
Oximino-piperidino-piperidine-based CCR5 antagonists. Part 2. Synthesis, SAR and biological evaluation of symmetrical heteroaryl carboxamides
-
Palani A., Shapiro S., Clader J.W., Greenlee W.J., Vice S., McCombie S., et al. Oximino-piperidino-piperidine-based CCR5 antagonists. Part 2. Synthesis, SAR and biological evaluation of symmetrical heteroaryl carboxamides. Bioorganic Medical Chemistry and Letters. 13:2003;709-712
-
(2003)
Bioorganic Medical Chemistry and Letters
, vol.13
, pp. 709-712
-
-
Palani, A.1
Shapiro, S.2
Clader, J.W.3
Greenlee, W.J.4
Vice, S.5
McCombie, S.6
-
82
-
-
0037162281
-
New class of HIV integrase inhibitors that block viral replication in cell culture
-
Pannecouque C., Pluymers W., Van Maele B., Tetz V., Cherepanov P., De Clercq E., et al. New class of HIV integrase inhibitors that block viral replication in cell culture. Current Biology. 12:2002;1169-1177
-
(2002)
Current Biology
, vol.12
, pp. 1169-1177
-
-
Pannecouque, C.1
Pluymers, W.2
Van Maele, B.3
Tetz, V.4
Cherepanov, P.5
De Clercq, E.6
-
83
-
-
0033856959
-
Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters
-
Pluymers W., Neamati N., Pannecouque C., Fikkert V., Marchand C., Burke T.R. Jr., et al. Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters. Molecular Pharmacology. 58:2000;641-648
-
(2000)
Molecular Pharmacology
, vol.58
, pp. 641-648
-
-
Pluymers, W.1
Neamati, N.2
Pannecouque, C.3
Fikkert, V.4
Marchand, C.5
Burke Jr., T.R.6
-
84
-
-
0036784324
-
Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives
-
Pluymers W., Pais G., Van Maele B., Pannecouque C., Fikkert V., Burke T.R. Jr., et al. Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives. Antimicrobial Agents and Chemotherapy. 46:2002;3292-3297
-
(2002)
Antimicrobial Agents and Chemotherapy
, vol.46
, pp. 3292-3297
-
-
Pluymers, W.1
Pais, G.2
Van Maele, B.3
Pannecouque, C.4
Fikkert, V.5
Burke Jr., T.R.6
-
85
-
-
0030895692
-
Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor
-
Poppe S.M., Slade D.E., Chong K.T., Hinshaw R.R., Pagano P.J., Markowitz M., et al. Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor. Antimicrobial Agents and Chemotherapy. 41:1997;1058-1063
-
(1997)
Antimicrobial Agents and Chemotherapy
, vol.41
, pp. 1058-1063
-
-
Poppe, S.M.1
Slade, D.E.2
Chong, K.T.3
Hinshaw, R.R.4
Pagano, P.J.5
Markowitz, M.6
-
86
-
-
1642495257
-
A randomized, double-blind, multicenter comparison of emtricitabine QD to stavudine BID in treatment-naïve HIV-infected patients
-
Paris, France, 14-17 July 2003, Abstracts.
-
Raffi, F., Saag, M., Cahn, P., Wolff, M., Pearce, D., & Molina, J., et al. (2003). A randomized, double-blind, multicenter comparison of emtricitabine QD to stavudine BID in treatment-naïve HIV-infected patients. In Proceedings of the 2nd IAS Conference on HIV and Pathogenesis. Paris, France, 14-17 July 2003, Abstracts.
-
(2003)
Proceedings of the 2nd IAS Conference on HIV and Pathogenesis
-
-
Raffi, F.1
Saag, M.2
Cahn, P.3
Wolff, M.4
Pearce, D.5
Molina, J.6
-
87
-
-
0034640387
-
Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse trancriptase involves extensive main chain hydrogen bonding
-
Ren J., Nichols C., Bird L.E., Fujiwara T., Sugimoto H., Stuart D.I., et al. Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse trancriptase involves extensive main chain hydrogen bonding. Journal of Biological Chemistry. 275:2000;14316-14320
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 14316-14320
-
-
Ren, J.1
Nichols, C.2
Bird, L.E.3
Fujiwara, T.4
Sugimoto, H.5
Stuart, D.I.6
-
88
-
-
0003339453
-
SCH C: Safety and antiviral effects of a CCR5 receptor antagonist in HIV-1 infected subjects
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Reynes, J., Rouzier, R., Kanouni, T., Baillat, V., Baroudy, B., & Keung, A. (2002). SCH C: Safety and antiviral effects of a CCR5 receptor antagonist in HIV-1 infected subjects. In Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections (no. 1, p. 53). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
(2002)
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
, Issue.1
, pp. 53
-
-
Reynes, J.1
Rouzier, R.2
Kanouni, T.3
Baillat, V.4
Baroudy, B.5
Keung, A.6
-
89
-
-
0034944610
-
Antiretroviral activity of emtricitabine, a potent nucleoside reverse transcriptase inhibitor
-
Richman D.D. Antiretroviral activity of emtricitabine, a potent nucleoside reverse transcriptase inhibitor. Antiviral Therapy. 6:2001;83-88
-
(2001)
Antiviral Therapy
, vol.6
, pp. 83-88
-
-
Richman, D.D.1
-
90
-
-
0031883832
-
Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides
-
Rimsky L.T., Shugars D.C., Matthews T.J. Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides. Journal of Virology. 72:1998;986-993
-
(1998)
Journal of Virology
, vol.72
, pp. 986-993
-
-
Rimsky, L.T.1
Shugars, D.C.2
Matthews, T.J.3
-
91
-
-
0037115019
-
Tenofovir disoproxil fumarate therapy for chronic hepatitis B in human immunodeficiency virus/hepatitis B virus-coinfected individuals for whom interferon-α and lamivudine therapy have failed
-
Ristig M.B., Crippin J., Aberg J.A., Powderly W.G., Lisker-Melman M., Kessels L., et al. Tenofovir disoproxil fumarate therapy for chronic hepatitis B in human immunodeficiency virus/hepatitis B virus-coinfected individuals for whom interferon-α and lamivudine therapy have failed. Journal of Infection and Disease. 186:2002;1844-1847
-
(2002)
Journal of Infection and Disease
, vol.186
, pp. 1844-1847
-
-
Ristig, M.B.1
Crippin, J.2
Aberg, J.A.3
Powderly, W.G.4
Lisker-Melman, M.5
Kessels, L.6
-
92
-
-
0034752631
-
Prototype trial design for rapid dose selection of antiretroviral drugs: An example using emtricitabine (Coviracil)
-
Rousseau F.S., Kahn J.O., Thompson M., Mildvan D., Shepp D., Sommadossi J.P., et al. Prototype trial design for rapid dose selection of antiretroviral drugs: An example using emtricitabine (Coviracil). Journal of Antimicrobial and Chemotherapy. 48:2001;507-513
-
(2001)
Journal of Antimicrobial and Chemotherapy
, vol.48
, pp. 507-513
-
-
Rousseau, F.S.1
Kahn, J.O.2
Thompson, M.3
Mildvan, D.4
Shepp, D.5
Sommadossi, J.P.6
-
93
-
-
0003259264
-
Study DPC 083-203, a phase II comparison of 100 and 200 mg once-daily DPC 083 and 2 NRTIs in patients failing a NNRTI-containing regimen
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Ruiz, N., Nusrat, R., Lauenroth-Mai, E., Berger, D., Walworth, C., & Bacheler, L. T., et al., The DPC 083-203 Study Team (2002). Study DPC 083-203, a phase II comparison of 100 and 200 mg once-daily DPC 083 and 2 NRTIs in patients failing a NNRTI-containing regimen. In Proceeding sof the 9th Conference on Retroviruses and Opportunistic Infections (no. 6, p. 55). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
(2002)
Proceeding Sof the 9th Conference on Retroviruses and Opportunistic Infections
, Issue.6
, pp. 55
-
-
Ruiz, N.1
Nusrat, R.2
Lauenroth-Mai, E.3
Berger, D.4
Walworth, C.5
Bacheler, L.T.6
-
94
-
-
0003259264
-
A phase II double-blind (DB) comparison of 3 once daily doses of the NNRTI DPC 083 vs. 600 mg efavirenz (EFV) in combination with 2 NRTIs in HIV antiretroviral (ARV) treatment-naïve patients
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Ruiz, N., Nusrat, R., Lazzarin, A., Arasteh, K., Goebel, F.-D., & Audagnotto, S., et al. (2002). A phase II double-blind (DB) comparison of 3 once daily doses of the NNRTI DPC 083 vs. 600 mg efavirenz (EFV) in combination with 2 NRTIs in HIV antiretroviral (ARV) treatment-naïve patients. In Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections (no. 7, p. 55). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
(2002)
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
, vol.7
, pp. 55
-
-
Ruiz, N.1
Nusrat, R.2
Lazzarin, A.3
Arasteh, K.4
Goebel, F.-D.5
Audagnotto, S.6
-
95
-
-
0034053044
-
Susceptibility to PNU-140690 (tipranavir) of human immunodeficiency virus type 1 isolates derived from patients with multidrug resistance to other protease inhibitors
-
Rusconi S., La Seta Catamancio S., Citterio P., Kurtagic S., Violin M., Balotta C., et al. Susceptibility to PNU-140690 (tipranavir) of human immunodeficiency virus type 1 isolates derived from patients with multidrug resistance to other protease inhibitors. Antimicrobial Agents and Chemotherapy. 44:2000;1328-1332
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, pp. 1328-1332
-
-
Rusconi, S.1
La Seta Catamancio, S.2
Citterio, P.3
Kurtagic, S.4
Violin, M.5
Balotta, C.6
-
96
-
-
0037692641
-
TMC125 monotherapy for 1 week results in a similar initial rate of decline of HIV-1 RNA as therapy with a 5-drug regimen
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Sankatsing, S., Weverling, G., van't Klooster, G., Prins, J., & Lange, J. TMC125 monotherapy for 1 week results in a similar initial rate of decline of HIV-1 RNA as therapy with a 5-drug regimen. In Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections (no. 5, p. 54). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
, Issue.5
, pp. 54
-
-
Sankatsing, S.1
Weverling, G.2
Van't Klooster, G.3
Prins, J.4
Lange, J.5
-
97
-
-
0037234238
-
Results of a phase 2 clinical trial at 48 weeks (AI424-007): A dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naïve subjects
-
Sanne I., Piliero P., Squires K., Thiry A., Schnittman S. Results of a phase 2 clinical trial at 48 weeks (AI424-007): A dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naïve subjects. Journal of Acquired Immune Deficiency Syndrome. 32:2003;18-29
-
(2003)
Journal of Acquired Immune Deficiency Syndrome
, vol.32
, pp. 18-29
-
-
Sanne, I.1
Piliero, P.2
Squires, K.3
Thiry, A.4
Schnittman, S.5
-
98
-
-
0036232997
-
DPC 817: A cytidine nucleoside analog with activity against zidovudine- and lamivudine-resistant viral variants
-
Schinazi R.F., Mellors J., Bazmi H., Diamond S., Garber S., Gallagher K., et al. DPC 817: A cytidine nucleoside analog with activity against zidovudine- and lamivudine-resistant viral variants. Antimicrobial Agents and Chemotherapy. 46:2002;1394-1401
-
(2002)
Antimicrobial Agents and Chemotherapy
, vol.46
, pp. 1394-1401
-
-
Schinazi, R.F.1
Mellors, J.2
Bazmi, H.3
Diamond, S.4
Garber, S.5
Gallagher, K.6
-
99
-
-
0011309256
-
AMD-3100, a CXCR4 antagonist, reduced HIV viral load and X4 virus levels in humans
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Schols, D., Claes, S., De Clercq, E., Hendrix, C., Bridger, G., & Calandra, G., et al., AMD-3100 HIV Study Group (2002). AMD-3100, a CXCR4 antagonist, reduced HIV viral load and X4 virus levels in humans. In Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections (no. 2, p. 53). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
(2002)
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
, Issue.2
, pp. 53
-
-
Schols, D.1
Claes, S.2
De Clercq, E.3
Hendrix, C.4
Bridger, G.5
Calandra, G.6
-
100
-
-
0041893844
-
Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist H
-
Boston, MA, USA, 10-14 February 2003, Abstracts.
-
Schols, D., Claes, S., Hatse, S., Princen, K., Vermeire, K., & De Clercq, et al. (2002). Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist H. In Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections (no. 563). Boston, MA, USA, 10-14 February 2003, Abstracts.
-
(2002)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
, Issue.563
-
-
Schols, D.1
Claes, S.2
Hatse, S.3
Princen, K.4
Vermeire, K.5
De Clercq6
-
101
-
-
0041893844
-
Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist
-
Proceedings of the 16th International Conference on Antiviral Research. Savannah, GA, USA, 27 April-1 May 2003;
-
Schols, D., Claes, S., Hatse, S., Princen, K., Vermeire, K., & De Clercq, E., et al. (2003). Anti-HIV activity profile of AMD070, an orally bioavailable CXCR4 antagonist. In Proceedings of the 16th International Conference on Antiviral Research. Savannah, GA, USA, 27 April-1 May 2003; Antiviral Research, 57, A39.
-
(2003)
Antiviral Research
, vol.57
-
-
Schols, D.1
Claes, S.2
Hatse, S.3
Princen, K.4
Vermeire, K.5
De Clercq, E.6
-
102
-
-
0038746305
-
Resistance to tipranavir is uncommon in a randomized trial of tipranavir/ritonavir (TPV/RTV) in multiple PI-failure patients (BI 1182.2)
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Schwartz, R., Kazanjian, P., Slater, L., Hathaway, B., Markowitz, M., & Wheeler, D., et al. (2002). Resistance to tipranavir is uncommon in a randomized trial of tipranavir/ritonavir (TPV/RTV) in multiple PI-failure patients (BI 1182.2). In Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections (no. 562-T, p. 261). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
(2002)
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
, Issue.562 T
, pp. 261
-
-
Schwartz, R.1
Kazanjian, P.2
Slater, L.3
Hathaway, B.4
Markowitz, M.5
Wheeler, D.6
-
103
-
-
0037474193
-
Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2,4-dioxobutanoic acid
-
Shaw-Reid C.A., Munshi V., Graham P., Wolfe A., Witmer M., Danzeisen R., et al. Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2, 4-dioxobutanoic acid. Journal of Biological Chemistry. 278:2003;2777-2780
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 2777-2780
-
-
Shaw-Reid, C.A.1
Munshi, V.2
Graham, P.3
Wolfe, A.4
Witmer, M.5
Danzeisen, R.6
-
104
-
-
0003289087
-
Efficacy and safety of tenofovir disoproxil fumarate (TDF) versus stavudine (d4T) when used in combination with lamivudine (3TC) and efavirenz (EFV) in HIV-1 infected patients naïve to antiretroviral therapy (ART): 48-week interim results
-
Barcelona, Spain, 7-12 July 2002, Abstracts.
-
Staszewski, S., Gallant, J., Pozniak, A., Suleiman, J. M. A. H., Dejesus, E., & Koenig, E., et al. (2002). Efficacy and safety of tenofovir disoproxil fumarate (TDF) versus stavudine (d4T) when used in combination with lamivudine (3TC) and efavirenz (EFV) in HIV-1 infected patients naïve to antiretroviral therapy (ART): 48-week interim results. In Proceedings of the XIV International Acquired Immunodeficiency Syndrome Conference (no. Or17). Barcelona, Spain, 7-12 July 2002, Abstracts.
-
(2002)
Proceedings of the XIV International Acquired Immunodeficiency Syndrome Conference
, Issue.OR17
-
-
Staszewski, S.1
Gallant, J.2
Pozniak, A.3
Suleiman, J.M.A.H.4
Dejesus, E.5
Koenig, E.6
-
105
-
-
0012774175
-
Efficacy and safety of tenofovir DF (TDF) versus stavudine (d4T) when used in combination with lamivudine and efavirenz in antiretroviral naïve patients: 96-week preliminary interim results
-
Boston, MA, USA, 10-14 February 2003, Abstracts.
-
Staszewski, S., Gallant, J. E., Pozniak, A. L., Suleiman, J. M. A. H., DeJesus, E., & Lu, B., et al. (2003). Efficacy and safety of tenofovir DF (TDF) versus stavudine (d4T) when used in combination with lamivudine and efavirenz in antiretroviral naïve patients: 96-week preliminary interim results. In Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections (no. 564b). Boston, MA, USA, 10-14 February 2003, Abstracts.
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections
, Issue.564 B
-
-
Staszewski, S.1
Gallant, J.E.2
Pozniak, A.L.3
Suleiman, J.M.A.H.4
DeJesus, E.5
Lu, B.6
-
108
-
-
0033998526
-
Antiviral activity of 2′-deoxy-3′-oxa-4′-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice
-
Stoddart C.A., Moreno M.E., Linquist-Stepps V.D., Bare C., Bogan M.R., Gobbi A., et al. Antiviral activity of 2′-deoxy-3′-oxa-4′- thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice. Antimicrobial Agents and Chemotherapy. 44:2000;783-786
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, pp. 783-786
-
-
Stoddart, C.A.1
Moreno, M.E.2
Linquist-Stepps, V.D.3
Bare, C.4
Bogan, M.R.5
Gobbi, A.6
-
109
-
-
2942617825
-
Activity of the cytidine analog reverset (RVT) against 3TC-resistant HIV-1 in SCID-hu Thy/Liv mice, HIV DART 2002. Frontiers in drug development for antiretroviral therapies (no. 023)
-
Naples, FL, USA, 15-19 December 2002; Abstracts.
-
Stoddart, C. A., Bozeman, C. A., & Schinazi, R. F. (2002). Activity of the cytidine analog reverset (RVT) against 3TC-resistant HIV-1 in SCID-hu Thy/Liv mice, HIV DART 2002. Frontiers in drug development for antiretroviral therapies (no. 023). Naples, FL, USA, 15-19 December 2002; Antiviral Research, Abstracts.
-
(2002)
Antiviral Research
-
-
Stoddart, C.A.1
Bozeman, C.A.2
Schinazi, R.F.3
-
110
-
-
0035940445
-
SCH-C (SCH 351125), an orally bioavailable% small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo
-
Strizki J.M., Xu S., Wagner N.E., Wojcik L., Liu J., Hou Y., et al. SCH-C (SCH 351125), an orally bioavailable% small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo. Proceedings of National Academy of United States of America. 98:2001;12718-12723
-
(2001)
Proceedings of National Academy of United States of America
, vol.98
, pp. 12718-12723
-
-
Strizki, J.M.1
Xu, S.2
Wagner, N.E.3
Wojcik, L.4
Liu, J.5
Hou, Y.6
-
111
-
-
0033986850
-
Safety assessment, in vitro and in vivo, and pharmacokinetics of emivirine, a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1
-
Szczech G.M., Furman P., Painter G.R., Barry D.W., Borroto-Esoda K., Grizzle T.B., et al. Safety assessment, in vitro and in vivo, and pharmacokinetics of emivirine, a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapy. 44:2000;123-130
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, pp. 123-130
-
-
Szczech, G.M.1
Furman, P.2
Painter, G.R.3
Barry, D.W.4
Borroto-Esoda, K.5
Grizzle, T.B.6
-
112
-
-
12944322516
-
Tipranavir (PNU-140690): A potent, orally bioavaible nonpeptidic HIV protease inhibitor of the 5,6-dihydro-4-hydroxy-2-pyrone sulfonamide class
-
Turner S.R., Strohbach J.W., Tommasi R.A., Aristoff P.A., Johnson P.D., Skulnick H.I., et al. Tipranavir (PNU-140690): A potent, orally bioavaible nonpeptidic HIV protease inhibitor of the 5, 6-dihydro-4-hydroxy-2-pyrone sulfonamide class. Journal of Medical Chemistry. 41:1998;3467-3476
-
(1998)
Journal of Medical Chemistry
, vol.41
, pp. 3467-3476
-
-
Turner, S.R.1
Strohbach, J.W.2
Tommasi, R.A.3
Aristoff, P.A.4
Johnson, P.D.5
Skulnick, H.I.6
-
113
-
-
0031893416
-
Inhibition of acute-, latent-, and chronic-phase human immunodeficiency virus type 1 (HIV-1) replication by a bistriazoloacridone analog that selectively inhibits HIV-1 transcription
-
Turpin J.A., Buckheit R.W. Jr., Derse D., Hollingshead M., Williamson K., Palamone C., et al. Inhibition of acute-, latent-, and chronic-phase human immunodeficiency virus type 1 (HIV-1) replication by a bistriazoloacridone analog that selectively inhibits HIV-1 transcription. Antimicrobial Agents and Chemotherapy. 42:1998;487-494
-
(1998)
Antimicrobial Agents and Chemotherapy
, vol.42
, pp. 487-494
-
-
Turpin, J.A.1
Buckheit Jr., R.W.2
Derse, D.3
Hollingshead, M.4
Williamson, K.5
Palamone, C.6
-
114
-
-
0037308267
-
Tenofovir disoproxil fumarate exhibits strong antiviral effect in a patient with lamivudine-resistant severe hepatitis B reactivation
-
Van Bömmel F., Schernick A., Hopf U., Berg T. Tenofovir disoproxil fumarate exhibits strong antiviral effect in a patient with lamivudine-resistant severe hepatitis B reactivation. Gastroenterology. 124:2003;586-587
-
(2003)
Gastroenterology
, vol.124
, pp. 586-587
-
-
Van Bömmel, F.1
Schernick, A.2
Hopf, U.3
Berg, T.4
-
115
-
-
0013415974
-
Safety, tolerability and pharmacokinetics of escalating singe oral doses of TMC 114, a novel protease inhibitor (PI) highly active against HIV-1 variants resistant to other Pis
-
Chicago, IL, USA, 16-19 December 2001, Abstracts, I-1934.
-
Van Der Geest, R., Van Der Sandt, I., Gille, D., Groen, K., Tritsmans, L., & Stoffels, P. (2001). Safety, tolerability and pharmacokinetics of escalating singe oral doses of TMC 114, a novel protease inhibitor (PI) highly active against HIV-1 variants resistant to other Pis. In Proceedings of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). Chicago, IL, USA, 16-19 December 2001, Abstracts, I-1934.
-
(2001)
Proceedings of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
-
-
Van Der Geest, R.1
Van Der Sandt, I.2
Gille, D.3
Groen, K.4
Tritsmans, L.5
Stoffels, P.6
-
116
-
-
0037111084
-
Topical administration of low-dose tenofovir disoproxil fumarate to protect infant macaques against multiple oral exposures of low doses of simian immunodeficiency virus
-
Van Rompay K.K.A., Schmidt K.A., Lawson J.R., Singh R., Bischofberger N., Marthas M.L. Topical administration of low-dose tenofovir disoproxil fumarate
-
(2002)
Journal of Infection and Disease
, vol.186
, pp. 1508-1513
-
-
Van Rompay, K.K.A.1
Schmidt, K.A.2
Lawson, J.R.3
Singh, R.4
Bischofberger, N.5
Marthas, M.L.6
-
117
-
-
0036436747
-
CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor
-
Vermeire K., Zhang Y., Princen K., Hatse S., Samala M.F., Dey K., et al. CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor. Virology. 302:2002;342-353
-
(2002)
Virology
, vol.302
, pp. 342-353
-
-
Vermeire, K.1
Zhang, Y.2
Princen, K.3
Hatse, S.4
Samala, M.F.5
Dey, K.6
-
118
-
-
0037220770
-
The anti-HIV potency of cyclotriazadisulfonamide analogs is directly correlated with their ability to down-modulate the CD4 receptor
-
Vermeire K., Bell T.W., Choi H.-J., Jin Q., Samala M.F., Sodoma A., et al. The anti-HIV potency of cyclotriazadisulfonamide analogs is directly correlated with their ability to down-modulate the CD4 receptor. Molecular Pharmacology. 63:2003;203-210
-
(2003)
Molecular Pharmacology
, vol.63
, pp. 203-210
-
-
Vermeire, K.1
Bell, T.W.2
Choi, H.-J.3
Jin, Q.4
Samala, M.F.5
Sodoma, A.6
-
119
-
-
2942533554
-
-
Submitted for publication.
-
Vermeire, K., Bell, T. W., Dey, K., Hatse, S., Princen, K., & De Clercq, et al. (2003). The CD4 down-modulating compound, CADA, is synergistic with multiple anti-HIV drugs in vitro, Submitted for publication.
-
(2003)
The CD4 Down-modulating Compound, CADA, Is Synergistic with Multiple Anti-HIV Drugs in Vitro
-
-
Vermeire, K.1
Bell, T.W.2
Dey, K.3
Hatse, S.4
Princen, K.5
De Clercq6
-
120
-
-
0034727864
-
4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells
-
Wai J.S., Egbertson M.S., Payne L.S., Fisher T.E., Embrey M.W., Tran L.O., et al. 4-Aryl-2, 4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells. Journal of Medical Chemistry. 43:2000;4923-4926
-
(2000)
Journal of Medical Chemistry
, vol.43
, pp. 4923-4926
-
-
Wai, J.S.1
Egbertson, M.S.2
Payne, L.S.3
Fisher, T.E.4
Embrey, M.W.5
Tran, L.O.6
-
121
-
-
0036090585
-
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
-
Wei X., Decker J.M., Liu H., Zhang Z., Arani R.B., Kilby J.M., et al. Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrobial Agents and Chemotherapy. 46:2002;1896-1905
-
(2002)
Antimicrobial Agents and Chemotherapy
, vol.46
, pp. 1896-1905
-
-
Wei, X.1
Decker, J.M.2
Liu, H.3
Zhang, Z.4
Arani, R.B.5
Kilby, J.M.6
-
122
-
-
0037330767
-
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists bearing 4-aminoheterocycle substituted piperidine side chains
-
Willoughby C.A., Rosauer K.G., Hale J.J., Budhu R.J., Mills S.G., Chapman K.T., et al. 1, 3, 4-Trisubstituted pyrrolidine CCR5 receptor antagonists bearing 4-aminoheterocycle substituted piperidine side chains. Bioorganic Medical Chemistry and Letters. 13:2003;427-431
-
(2003)
Bioorganic Medical Chemistry and Letters
, vol.13
, pp. 427-431
-
-
Willoughby, C.A.1
Rosauer, K.G.2
Hale, J.J.3
Budhu, R.J.4
Mills, S.G.5
Chapman, K.T.6
-
123
-
-
0036145503
-
A potent human immunodeficiency virus type 1 protease inhibitor, UIC-94003 (TMC-126), and selection of a novel (A28S) mutation in the protease active site
-
Yoshimura K., Kato R., Kavlick M.F., Nguyen A., Maroun V., Maeda K., et al. A potent human immunodeficiency virus type 1 protease inhibitor, UIC-94003 (TMC-126), and selection of a novel (A28S) mutation in the protease active site. Journal of Virology. 76:2002;1349-1358
-
(2002)
Journal of Virology
, vol.76
, pp. 1349-1358
-
-
Yoshimura, K.1
Kato, R.2
Kavlick, M.F.3
Nguyen, A.4
Maroun, V.5
Maeda, K.6
-
124
-
-
0003203586
-
S-1360: In vitro activity of a new HIV-1 integrase inhibitor in clinical development
-
Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
Yoshinaga, T., Sato, A., Fujishita, T., & Fujiwara, T. (2002). S-1360: In vitro activity of a new HIV-1 integrase inhibitor in clinical development. In Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections (no. 8, p. 55). Seattle, Washington, USA, 24-28 February 2002, Abstracts.
-
(2002)
Proceedings of the 9th Conference on Retroviruses and Opportunistic Infections
, Issue.8
, pp. 55
-
-
Yoshinaga, T.1
Sato, A.2
Fujishita, T.3
Fujiwara, T.4
-
125
-
-
0037463757
-
Azido-containing aryl β-diketo acid HIV-1 integrase inhibitors
-
Zhang X., Pais G.C.G., Svarovskaia E.S., Marchand C., Johnson A.A., Karki R.G., et al. Azido-containing aryl β-diketo acid HIV-1 integrase inhibitors. Bioorganic Medical Chemistry and Letters. 13:2003;1215-1219
-
(2003)
Bioorganic Medical Chemistry and Letters
, vol.13
, pp. 1215-1219
-
-
Zhang, X.1
Pais, G.C.G.2
Svarovskaia, E.S.3
Marchand, C.4
Johnson, A.A.5
Karki, R.G.6
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