메뉴 건너뛰기




Volumn 21, Issue 4, 2002, Pages 483-492

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

Author keywords

Cancer; Cell cycle; Centrosome anomalies; Chromosomal instability

Indexed keywords

AURORA A; GENE PRODUCT; PHOSPHOTRANSFERASE; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 0037084163     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.4.483     Document Type: Article
Times cited : (591)

References (62)
  • 4
    • 0032100685 scopus 로고    scopus 로고
    • A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
    • (1998) EMBO J. , vol.17 , pp. 3052-3065
    • Bischoff, J.R.1
  • 10
    • 0035854383 scopus 로고    scopus 로고
    • The mouse mps1 p-like kinase regulates centrosome duplication
    • (2001) Cell , vol.106 , pp. 95-104
    • Fisk, H.A.1    Winey, M.2
  • 12
    • 0032518798 scopus 로고    scopus 로고
    • A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
    • (1998) EMBO J. , vol.17 , pp. 470-481
    • Fry, A.M.1    Meraldi, P.2    Nigg, E.A.3
  • 15
    • 0032716628 scopus 로고    scopus 로고
    • Aurora/Ip11p-related kinases, a new oncogenic family of mitotic serine-threonine kinases
    • (1999) J. Cell Sci. , vol.112 , pp. 3591-3601
    • Giet, R.1    Prigent, C.2
  • 19
  • 30
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 42
    • 0034595292 scopus 로고    scopus 로고
    • Kipl, polyploidy and centrosome overduplication
    • (2000) EMBO J. , vol.19 , pp. 2069-2081
    • Nakayama, K.1
  • 45
    • 0034730321 scopus 로고    scopus 로고
    • Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication
    • (2000) Cell , vol.103 , pp. 127-140
    • Okuda, M.1
  • 51
    • 0030962953 scopus 로고    scopus 로고
    • A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines
    • (1997) Oncogene , vol.14 , pp. 2195-2200
    • Sen, S.1    Zhou, H.2    White, R.A.3
  • 53
    • 0032489332 scopus 로고    scopus 로고
    • cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 285-292
    • Shindo, M.1
  • 56
    • 0035907040 scopus 로고    scopus 로고
    • Centrosome duplication. A centriolar pas de deux
    • (2001) Cell , vol.105 , pp. 417-420
    • Stearns, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.