Downregulation of human polo-like kinase activity by antisense oligonucleotides induces growth inhibition in cancer cells

Oncogene

Volumn 21, Issue 20, 2002, Pages 3162-3171

  Spänkuch Schmitt, Birgit ^a   Wolf, Georg ^a   Solbach, Christine ^a   Loibl, Sibylle ^a   Knecht, Rainald ^a   Stegmüller, Manfred ^a   Von Minckwitz, Gunter ^a   Kaufmann, Manfred ^a   Strebhardt, Klaus ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Anticancer activity; Antisense; Polo like kinase; Xenograft

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; GENE PRODUCT; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; PHOSPHOTRANSFERASE; POLO LIKE KINASE; POLO LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; CENTROSOME; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG POTENCY; DRUG TOLERABILITY; ENZYME ACTIVITY; ENZYME REGULATION; ESOPHAGUS CARCINOMA; GENE ISOLATION; GENE OVEREXPRESSION; GROWTH INHIBITION; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MELANOMA; MITOSIS; NUCLEOTIDE METABOLISM; PHENOTYPE; PLK1 GENE; PRIORITY JOURNAL; PROGNOSIS; SPECIES IDENTIFICATION; UTERINE CERVIX CARCINOMA;

EID: 0037046495     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205412     Document Type: Article

References (39)