Complexity in the spindle checkpoint

Current Opinion in Genetics and Development

Volumn 10, Issue 1, 2000, Pages 26-31

  Burke, Daniel J ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE; CELL VIABILITY; CHROMOSOME SEGREGATION; MICROTUBULE; MITOSIS; MITOSIS SPINDLE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SISTER CHROMATID;

EID: 0033998013     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(99)00040-4     Document Type: Review

References (37)

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12. •].).
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17. 1 stage of the cell cycle.
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22. •].).
23. •]) that Cdc14 is sequestered in the nucleolus and that the localization depends on the MEN.
24. ••].).
25. ••]) that Pds1 inhibits both mitotic transitions and functions in both the DNA damage and spindle checkpoints. There is additional evidence that Esp1 functions at both transitions.
26. ••].).
27. ••]) that Bub2 is localized to the spindle pole and defines a distinct branch of the spindle checkpoint. Sister chromatid separation is delayed in a bub2 mutant treated with nocodazole suggesting that Bub2 does not inhibit the metaphase→anaphase transition.
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