Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (Taxol)-exposed cells

Molecular and Cellular Biology

Volumn 23, Issue 16, 2003, Pages 5556-5571

  Burns, Timothy F ^a   Fei, Peiwen ^a   Scata, Kimberly A ^a   Dicker, David T ^a   El Deiry, Wafik S ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; ETOPOSIDE; NOCODAZOLE; PACLITAXEL; POLO LIKE KINASE 2; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; RNA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; MITOSIS; MITOSIS SPINDLE; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL DEATH; CELL LINE; CHROMATIN; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FLOW CYTOMETRY; G1 PHASE; GENE SILENCING; GENES, P53; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; IN SITU HYBRIDIZATION; LUCIFERASES; LUMINESCENT PROTEINS; MICE; MICE, TRANSGENIC; MICROTUBULES; MITOSIS; MODELS, BIOLOGICAL; PACLITAXEL; PLASMIDS; PRECIPITIN TESTS; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES; TEMPERATURE; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0042132030     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.16.5556-5571.2003     Document Type: Article

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