Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

Current Biology

Volumn 10, Issue 21, 2000, Pages 1319-1328

  Uren, Anthony G ^a   Wong, Lee ^b   Pakusch, Miha ^a   Fowler, Kerry J ^b   Burrows, Francis J ^c   Vaux, David L ^a   Choo, K H Andy ^b  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; AURORA KINASE; BACULOVIRUS; BIOLOGICAL FUNCTIONS; CELL DIVISION; CENTROMERE; ENZYME REGULATION; GENE DELETION; INNER CENTROMERE PROTEIN; PHENOTYPE; PREVENTION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SURVIVIN;

EID: 0034597594     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00769-7     Document Type: Article

References (58)

1. An apoptosis inhibiting baculovirus gene with a zinc finger like motif
2. Conservation of baculovirus inhibitor of apoptosis repeat proteins BIRps in viruses, nematodes, vertebrates and yeasts
3. Solution structure of a baculoviral inhibitor of apoptosis IAP repeat
4. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
5. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
6. A conserved family of cellular genes related to the baculovirus IAP gene and encoding apoptosis inhibitors
7. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral-inhibitor of apoptosis proteins
8. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death
9. The Drosophila caspase DRONC is regulated by DIAP1
10. IAP family proteins - Suppressors of apoptosis
11. Caenorhabditis elegans inhibitor of apoptosis protein IAP homologue BIR-1 plays a conserved role in cytokinesis
12. Role for yeast inhibitor of apoptosis IAP-like proteins in cell division
13. Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events
14. S. pombe Pbh1p: An inhibitor of apoptosis domain containing protein is essential for chromosome segregation
15. The survivin-like C. elegans BIR-1 protein acts with the aurora-like kinase AIR-2 to control chromosome behavior and spindle midzone organization
16. INCENP centromere and spindle targeting: Identification of essential conserved motifs and involvement of heterochromatin protein HP1
17. The INCENPs - Structural and functional analysis of a family of chromosome passenger proteins
18. Colocalization of TD-60 and INCENP throughout G2 and mitosis: Evidence for their possible interaction in signalling cytokinesis
19. The Aurora/Ipl1p kinase family: Regulators of chromosome segregation and cytokinesis
20. Aim-1 - A mammalian midbody-associated protein required for cytokinesis
21. Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene incenpdisrupted mice
22. A dominant mutant of inner centromere protein INCENP, a chromosomal protein, disrupts prometaphase congression and cytokinesis
23. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
24. Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation
25. Control of apoptosis and mitotic spindle checkpoint by survivin
26. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function
27. Human centromeres and neocentromeres show identical distribution patterns of > 20 functionally important kinetochore-associated proteins
28. PolyADP-ribose polymerase at active centromeres and neocentromeres at metaphase
29. Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and Hbubr1
30. The image consortium - An integrated molecular analysis of genomes and their expression
31. Molecular cloning of effector cell protease receptor-1, a novel cell surface receptor for the protease factor Xa
32. Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting
33. The elusive factor Xa receptor: Failure to detect transcripts that correspond to the published sequence of EPR-1
34. Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression
35. The cancer antiapoptosis mouse survivin gene: Characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression
36. CENP-B: A major human centromere protein located beneath the kinetochore
37. Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase
38. CENP-F is a Ca 400 kDa kinetochore protein that exhibits a cell-cycle dependent localization
39. Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres
40. The inner centromere protein INCENP antigens: Movement from inner centromere to midbody during mitosis
41. Analysis of the distribution of the INCENPs throughout mitosis reveals the existence of a pathway of structural changes in the chromosomes during metaphase and early events in cleavage furrow formation
42. Chromosomal proteins and cytokinesis: Patterns of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells
43. CENP-E is a putative kinetochore motor that accumulates just before mitosis
44. Mitotic HeLa cells contain a CENP-E-associated minus end-directed microtubule motor
45. The vertebrate cell kinetochore and its roles during mitosis
46. Sli15 associates with the Ip11 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae
47. The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast
48. Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p
49. Regulation of chromosome segregation by Glc8p, a structural homolog of mammalian inhibitor 2 that functions as both an activator and an inhibitor of yeast protein phosphatase 1
50. AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos
51. INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
52. Incenp and an Aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis
53. The Aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis
54. Targeted disruption of the MHC Class-II A gene in C57BI/6 mice
55. A functional neo-centromere formed through activation of a latent human centromere and consisting of non-α-satellite DNA
56. Centromere protein B null mice are mitotically and meiotically normal but have lower body and testis weights