Prophase destruction of Emi1 by the SCFβTrCP/Slimb ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

Developmental Cell

Volumn 4, Issue 6, 2003, Pages 813-826

  Margottin Goguet, Florence ^a   Hsu, Jerry Y ^a   Loktev, Alexander ^a   Hsieh, Harn Mei ^a   Reimann, Julie D R ^a   Jackson, Peter K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ANAPHASE PROMOTING COMPLEX; CELL CYCLE PROTEIN; CYCLIN B; PROTEIN EMI1; PROTEIN KINASE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL MATURATION; CENTROSOME; CONSENSUS SEQUENCE; CONTROLLED STUDY; DROSOPHILA; GENE ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; HYPOTHESIS; MITOSIS; MOLECULAR RECOGNITION; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROPHASE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; BINDING SITES; CDC2 PROTEIN KINASE; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CONSENSUS SEQUENCE; CYCLIN A; CYCLIN B; DROSOPHILA PROTEINS; ENZYME ACTIVATION; F-BOX PROTEINS; GTP-BINDING PROTEINS; HUMANS; MITOSIS; MODELS, BIOLOGICAL; MUTATION; NOCODAZOLE; OOCYTES; PEPTIDE SYNTHASES; PHOSPHORYLATION; SKP CULLIN F-BOX PROTEIN LIGASES; SWINE; TIME FACTORS; XENOPUS; XENOPUS PROTEINS;

ANIMALIA;

EID: 0037534899     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(03)00153-9     Document Type: Article

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