Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 10, 2003, Pages 5789-5794

  Liu, Xiaoqi ^a   Erikson, Raymond L ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOTRANSFERASE; POLO LIKE KINASE 1; RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL DESTRUCTION; CANCER DIAGNOSIS; CANCER THERAPY; CELL CYCLE; CELL PROLIFERATION; CELL SORTER; CELL VIABILITY; CONTROLLED STUDY; DISEASE MARKER; DNA CONTENT; DNA DAMAGE; DNA DETERMINATION; DNA VECTOR; ENZYME ACTIVATION; ENZYME DEFICIENCY; GENE DISRUPTION; GENE FUNCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LETHALITY; MITOSIS INHIBITION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SISTER CHROMATID EXCHANGE;

AMINO ACID SEQUENCE; ANDROSTADIENES; ANIMALS; APOPTOSIS; BASE SEQUENCE; CAFFEINE; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL SURVIVAL; GENE DELETION; HELA CELLS; HUMANS; MICE; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSFECTION; TUMOR CELLS, CULTURED;

MAMMALIA;

EID: 0038624074     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1031523100     Document Type: Article

References (19)

1. Glover, D. M., Hagan, I. M. & Tavares, A. A. M. (1998) Genes Dev. 12, 3777-3787.
2. Nigg, E. A. (1998) Curr. Opin. Cell Biol. 10, 776-783.
3. Liu, X. & Erikson, R. L. (2002) Proc. Natl. Acad. Sci. USA 99, 8672-8676.
4. Strebhardt, K. (2001) in PLK (Polo-Like Kinase): Encyclopedia of Molecular Medicine, ed. Creighton, T. E. (Wiley, New York), pp. 2530-2532.
5. Knecht, R., Elez, R., Oechler, M., Solbach, C., von Ilberg, C. & Strebhardt, K. (1999) Cancer Res. 59, 2794-2797.
6. Knecht, R., Oberhauser, C. & Strebhardt, K. (2000) Int. J. Cancer 89, 535-536.
7. Smith, M. R., Wilson, M. L., Hamanaka, R., Chase, D., Kung, H., Longo, D. L. & Ferris, D. K. (1997) Biochem. Biophys. Res. Commun. 234, 397-405.
8. Sui, G., Soohoo, C., Affar, E. B., Gay, F., Shi, Y., Forrester, W. C. & Shi, Y. (2002) Proc. Natl. Acad. Sci. USA 99, 5515-5520.
9. Igney, F. H. & Krammer, P. H. (2002) Nat. Rev. 2, 277-288.
10. Miyashita, T. & Reed, J. C. (1995) Cell 80, 293-299.
11. Schultz, L. B., Chehab, N. H., Malikzay, A. & Halazonetis, T. D. (2000) J. Cell Biol. 151, 1381-1390.
12. Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M. & Bonner, W. M. (2000) Curr. Biol. 10, 886-895.
13. Blasina, A., Price, B. D., Turenne, G. A. & McGowan, C. H. (1999) Curr. Biol. 9, 1135-1138.
14. Sarkaria, J. N., Busby, E. C., Tibbetts, R. S., Roos, P., Taya, Y., Karnitz, L. M. & Abraham, R. T. (1999) Cancer Res. 59, 4375-4382.
15. Sarkaria, J. N., Tibbetts, R. S., Busby, E. C., Kennedy, A. P., Hill, D. E. & Abraham, R. T. (1998) Cancer Res. 58, 4375-4382.
16. Alexandru, G., Uhlmann, F., Mechtler, K., Poupart, M. & Nasmyth, K. (2001) Cell 105, 459-472.
17. Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S. & Bonner, W. M. (1998) J. Biol. Chem. 273, 5858-5868.
18. Rogakou, E. P., Nieves-Neira, W., Boon, C., Pommier, Y. & Bonner, W. M. (2000). J. Biol. Chem. 275, 9390-9395.
19. Spankuch-Schmitt, B., Bereiter-Hahn, J., Kaufmann, M. & Strebhardt, K. (2002) J. Natl. Cancer Inst. 94, 1863-1877.