Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

Nature Medicine

Volumn 2, Issue 1, 1996, Pages 72-79

  Wahl, Alan F ^a   Donaldson, Karen L ^a   Fairchild, Craig ^a   Lee, Frank Y F ^a   Foster, Scott A ^b   William Demers, G ^b   Galloway, Denise A ^b  

^a BRISTOL MYERS SQUIBB   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PACLITAXEL; PROTEIN P21; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOLOGY; CYTOTOXICITY; DRUG SENSITIZATION; FIBROBLAST; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; G2 PHASE; HELA CELLS; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOSIS; ONCOGENE PROTEINS, VIRAL; PACLITAXEL; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; HUMAN PAPILLOMAVIRUS TYPE 16;

EID: 0030026934     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0196-72     Document Type: Article

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