-
1
-
-
0036174704
-
Decreased plasma orexin-A levels in obese individuals
-
Adam JA, Menheere PP, van Dielen FM, Soeters PB, Buurman WA, Greve JW. 2002. Decreased plasma orexin-A levels in obese individuals. Int J Obes Relat Disord 26:274-276.
-
(2002)
Int. J. Obes. Relat. Disord.
, vol.26
, pp. 274-276
-
-
Adam, J.A.1
Menheere, P.P.2
van Dielen, F.M.3
Soeters, P.B.4
Buurman, W.A.5
Greve, J.W.6
-
2
-
-
0035912663
-
Identification and characterization of a Melanin-concentrating hormone receptor
-
An S, Cutler G, Zhao JJ, Huang SG, Tian H, Li W, Liang L, Rich M, Bakleh A, Du J, Chen JL, Dai K. 2001. Identification and characterization of a Melanin-concentrating hormone receptor. Proc Natl Acad Sci USA 98:7576-7581.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7576-7581
-
-
An, S.1
Cutler, G.2
Zhao, J.J.3
Huang, S.G.4
Tian, H.5
Li, W.6
Liang, L.7
Rich, M.8
Bakleh, A.9
Du, J.10
Chen, J.L.11
Dai, K.12
-
3
-
-
0034769247
-
Effects of leptin on the differentiation and metabolism of human adipocytes
-
Aprath-Husmann I, Rohring K, Gottschling-Zeller H, Skurk T, Scriba D, Birgel M, Hauner H. 2001. Effects of leptin on the differentiation and metabolism of human adipocytes. Int J Obes Relat Disord 25:1465-1470.
-
(2001)
Int. J. Obes. Relat. Disord.
, vol.25
, pp. 1465-1470
-
-
Aprath-Husmann, I.1
Rohring, K.2
Gottschling-Zeller, H.3
Skurk, T.4
Scriba, D.5
Birgel, M.6
Hauner, H.7
-
4
-
-
0038304457
-
Antagonism of ghrelin receptor reduces food intake and body weight gain in mice
-
Asakawa A, Inui A, Kaga T, Katsuura G, Fujimiya M, Fujino MA, Kasuga M. 2003. Antagonism of ghrelin receptor reduces food intake and body weight gain in mice. Gut 52:947-952.
-
(2003)
Gut.
, vol.52
, pp. 947-952
-
-
Asakawa, A.1
Inui, A.2
Kaga, T.3
Katsuura, G.4
Fujimiya, M.5
Fujino, M.A.6
Kasuga, M.7
-
5
-
-
0034127008
-
Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behavior and hypersensitive to stress
-
Bale TL, Contarion A, Smith CW, Chan R, Cold LH, Sawebenko FE, Koob CF, Vale WW, Lee KF. 2000. Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behavior and hypersensitive to stress. Nat Genet 24:410-414.
-
(2000)
Nat. Genet.
, vol.24
, pp. 410-414
-
-
Bale, T.L.1
Contarion, A.2
Smith, C.W.3
Chan, R.4
Cold, L.H.5
Sawebenko, F.E.6
Koob, C.F.7
Vale, W.W.8
Lee, K.F.9
-
6
-
-
10744225368
-
Regulation of fated blood glucose by resistin
-
Banerjee RR, Rangwata SM, Shapiro JS, Rich AS, Rhoades B, Qi Y, Wang J, Rajata MW, Pocai A, Scherer PE, Steppan CM, Ahima RS, Obici S, Rossetti L, Lazar MA. 2004. Regulation of fated blood glucose by resistin. Science 303:1195-1198.
-
(2004)
Science
, vol.303
, pp. 1195-1198
-
-
Banerjee, R.R.1
Rangwata, S.M.2
Shapiro, J.S.3
Rich, A.S.4
Rhoades, B.5
Qi, Y.6
Wang, J.7
Rajata, M.W.8
Pocai, A.9
Scherer, P.E.10
Steppan, C.M.11
Ahima, R.S.12
Obici, S.13
Rossetti, L.14
Lazar, M.A.15
-
7
-
-
0037244070
-
Is obesity a disease of the blood-brain barrier? physiological, pathological, and evolutionary considerations
-
Banks WA. 2003. Is obesity a disease of the blood-brain barrier? physiological, pathological, and evolutionary considerations. Curr Pharmacol Des 9:801-809.
-
(2003)
Curr. Pharmacol. Des.
, vol.9
, pp. 801-809
-
-
Banks, W.A.1
-
8
-
-
2342449315
-
Triglycerides induce leptin resistance at the blood-brain barrier
-
Banks WA, Coon AB, Robinson SM, Moinuddin A, Shultz JM, Nakaoke I, Morley JE. 2004. Triglycerides induce leptin resistance at the blood-brain barrier. Diabetes 53:1253-1260.
-
(2004)
Diabetes
, vol.53
, pp. 1253-1260
-
-
Banks, W.A.1
Coon, A.B.2
Robinson, S.M.3
Moinuddin, A.4
Shultz, J.M.5
Nakaoke, I.6
Morley, J.E.7
-
9
-
-
0033128358
-
The brain-pituitary-adipocyte axis
-
Barb CR. 1999. The brain-pituitary-adipocyte axis. J Anim Sci 77:1249-1257.
-
(1999)
J. Anim. Sci.
, vol.77
, pp. 1249-1257
-
-
Barb, C.R.1
-
10
-
-
1442352339
-
Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: Peroxisome proliferator-activated receptor agonists provide a rational therapeutic approach
-
Bays H, Mandarino L, DeFronzo RA. 2004. Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: Peroxisome proliferator-activated receptor agonists provide a rational therapeutic approach. J Clin Endocrinol Metab 89:463-478.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 463-478
-
-
Bays, H.1
Mandarino, L.2
DeFronzo, R.A.3
-
11
-
-
0037374766
-
The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells
-
Bensaid M, Gary-Bobo M, Esclangon A, Maffraud JP, Le Fur G, Oury-Donat F, Soubrie P. 2003. The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Mol Pharmacol 63:908-914.
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 908-914
-
-
Bensaid, M.1
Gary-Bobo, M.2
Esclangon, A.3
Maffraud, J.P.4
Le Fur, G.5
Oury-Donat, F.6
Soubrie, P.7
-
12
-
-
0032014178
-
Identification of SOCS-3 as a potential mediator of central leptin resistance
-
Bjorback C, Elmquist JK, Frantz JD, Shoelson SE, Flier JS. 1998. Identification of SOCS-3 as a potential mediator of central leptin resistance. Mol Cell 1:619-625.
-
(1998)
Mol. Cell
, vol.1
, pp. 619-625
-
-
Bjorback, C.1
Elmquist, J.K.2
Frantz, J.D.3
Shoelson, S.E.4
Flier, J.S.5
-
13
-
-
0036068133
-
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance
-
Bluher M, Michael MD, Peroni OD, Ueki K, Carter N, Kahn BB, Kahn CR. 2002. Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. Dev Cell 3:25-38.
-
(2002)
Dev. Cell
, vol.3
, pp. 25-38
-
-
Bluher, M.1
Michael, M.D.2
Peroni, O.D.3
Ueki, K.4
Carter, N.5
Kahn, B.B.6
Kahn, C.R.7
-
14
-
-
0030010181
-
Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line
-
Boston BA, Cone RD. 1996. Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line. Endocrinology 137:2043-2050.
-
(1996)
Endocrinology
, vol.137
, pp. 2043-2050
-
-
Boston, B.A.1
Cone, R.D.2
-
15
-
-
8844255630
-
Free fatty acids in obesity and type 2 diabetes: Definiting their role in the development of insulin resistance and β-cell dysfunction
-
Boden G, Shulman GI. 2002. Free fatty acids in obesity and type 2 diabetes: Definiting their role in the development of insulin resistance and β-cell dysfunction: Eur J Clin Invest 32:14-23.
-
(2002)
Eur. J. Clin. Invest.
, vol.32
, pp. 14-23
-
-
Boden, G.1
Shulman, G.I.2
-
16
-
-
0036341292
-
Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist
-
Borwsky BM, Durkin MM, Ogozalck K, Marzabadi MR, DeLeon J, Lagu B, Heurich R, Lichtblau H, Shaposhnik Z, Daniewska I, Blackburn TP, Branchek TA, Gerald C, Vaysse PJ, Forray C. 2002. Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist. Nat Med 8:825-830.
-
(2002)
Nat. Med.
, vol.8
, pp. 825-830
-
-
Borwsky, B.M.1
Durkin, M.M.2
Ogozalck, K.3
Marzabadi, M.R.4
DeLeon, J.5
Lagu, B.6
Heurich, R.7
Lichtblau, H.8
Shaposhnik, Z.9
Daniewska, I.10
Blackburn, T.P.11
Branchek, T.A.12
Gerald, C.13
Vaysse, P.J.14
Forray, C.15
-
17
-
-
0033923004
-
Melanin-concentrating hormone regulates leptin synthesis and secretion in rat adipocytes
-
Bradley RL, Kokkotou EG, Maratos-Flier E, Cheatham B. 2000. Melanin-concentrating hormone regulates leptin synthesis and secretion in rat adipocytes. Diabetes 49:1073-1077.
-
(2000)
Diabetes
, vol.49
, pp. 1073-1077
-
-
Bradley, R.L.1
Kokkotou, E.G.2
Maratos-Flier, E.3
Cheatham, B.4
-
19
-
-
0032731559
-
Neuropeptide Y, leptin, galanin and insulin in women with polycystic ovary syndrome
-
Baranowska B, Radzikoeska M, Wasilewska-Dziubinska E, Kaplinski A, Roguski K, Plonowski A. 1999. Neuropeptide Y, leptin, galanin and insulin in women with polycystic ovary syndrome. Gynecol Endocrinol 13:344-351.
-
(1999)
Gynecol. Endocrinol.
, vol.13
, pp. 344-351
-
-
Baranowska, B.1
Radzikoeska, M.2
Wasilewska-Dziubinska, E.3
Kaplinski, A.4
Roguski, K.5
Plonowski, A.6
-
20
-
-
0034008318
-
Synergistic effects of interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha: Central monoamine, corticosterone, and behavioral variations
-
Brebner K, Hayley S, Zacharko R, Merall Z, Anisman H. 2000. Synergistic effects of interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha: Central monoamine, corticosterone, and behavioral variations. Neuropyschopharmacology 22:566-580.
-
(2000)
Neuropyschopharmacology
, vol.22
, pp. 566-580
-
-
Brebner, K.1
Hayley, S.2
Zacharko, R.3
Merall, Z.4
Anisman, H.5
-
21
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Bruning JC, Gautam D, Burks DJ, Gillette J, Schubert M, Orban PC, Klein R, Krone W, Muller-Wieland D, Kahn CR. 2000. Role of brain insulin receptor in control of body weight and reproduction. Science 289:2066-2067.
-
(2000)
Science
, vol.289
, pp. 2066-2067
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
Orban, P.C.6
Klein, R.7
Krone, W.8
Muller-Wieland, D.9
Kahn, C.R.10
-
22
-
-
0042466384
-
Regulation of adiponectin by adipose tissue-derived cyctokines: In vivo and in vitro investigations in humans
-
Bruun JM, Lihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B. 2003. Regulation of adiponectin by adipose tissue-derived cyctokines: In vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab 285:E527-E533.
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.285
-
-
Bruun, J.M.1
Lihn, A.S.2
Verdich, C.3
Pedersen, S.B.4
Toubro, S.5
Astrup, A.6
Richelsen, B.7
-
23
-
-
0030013475
-
Tissue distribution of messenger ribonucleic acid encoding the rat glucagons-like peptide-1 receptor
-
Bullock BP, Heller RS, Habener JF. 1996. Tissue distribution of messenger ribonucleic acid encoding the rat glucagons-like peptide-1 receptor. Endocrinology 137:2968-2978.
-
(1996)
Endocrinology
, vol.137
, pp. 2968-2978
-
-
Bullock, B.P.1
Heller, R.S.2
Habener, J.F.3
-
24
-
-
0030594830
-
Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
-
Caro JF, Kolacznski JW, Nyce MR, Ohannesian JP, Opentanova I, Goldman WH, Lynn RB, Zhang PL, Sinha MK, Considine RV. 1996. Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance. Lancet 348:159-161.
-
(1996)
Lancet
, vol.348
, pp. 159-161
-
-
Caro, J.F.1
Kolacznski, J.W.2
Nyce, M.R.3
Ohannesian, J.P.4
Opentanova, I.5
Goldman, W.H.6
Lynn, R.B.7
Zhang, P.L.8
Sinha, M.K.9
Considine, R.V.10
-
25
-
-
0033566128
-
Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1
-
Chambers J, Ames RS, Bergsma D, Muir A, Fitzgerald LR, Hervieu G, Dytko GM, Foley JJ, Martin J, Liu WS, Park J, Ellis C, Ganguly S, Konchar S, Cluderay J, Leslie R, Wilson S, Sarau HM. 1999. Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1. Nature 400:261-265.
-
(1999)
Nature
, vol.400
, pp. 261-265
-
-
Chambers, J.1
Ames, R.S.2
Bergsma, D.3
Muir, A.4
Fitzgerald, L.R.5
Hervieu, G.6
Dytko, G.M.7
Foley, J.J.8
Martin, J.9
Liu, W.S.10
Park, J.11
Ellis, C.12
Ganguly, S.13
Konchar, S.14
Cluderay, J.15
Leslie, R.16
Wilson, S.17
Sarau, H.M.18
-
26
-
-
0033588184
-
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
-
Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M. 1999. Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation. Cell 98:409-412.
-
(1999)
Cell
, vol.98
, pp. 409-412
-
-
Chemelli, R.M.1
Willie, J.T.2
Sinton, C.M.3
Elmquist, J.K.4
Scammell, T.5
Lee, C.6
Richardson, J.A.7
Williams, S.C.8
Xiong, Y.9
Kisanuki, Y.10
Fitch, T.E.11
Nakazato, M.12
Hammer, R.E.13
Saper, C.B.14
Yanagisawa, M.15
-
27
-
-
0033818103
-
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body weight
-
Chen AS, Marsh DJ, Trumbauer ME, Frazier EG, Guan X-M, Yu H, Rosenblum CI, Vongs A, Feng Y, Cao L, Metzger JM, Strack AM, Camacho RE, Mellin TN, Nunes CN, Min W, Fisher J, Goapal-Trter S, MacIntyre DE, Chen HY, Van der Ploeg LHT. 2000. Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body weight. Nat Genet 26:97-102.
-
(2000)
Nat. Genet.
, vol.26
, pp. 97-102
-
-
Chen, A.S.1
Marsh, D.J.2
Trumbauer, M.E.3
Frazier, E.G.4
Guan, X.-M.5
Yu, H.6
Rosenblum, C.I.7
Vongs, A.8
Feng, Y.9
Cao, L.10
Metzger, J.M.11
Strack, A.M.12
Camacho, R.E.13
Mellin, T.N.14
Nunes, C.N.15
Min, W.16
Fisher, J.17
Goapal-Trter, S.18
MacIntyre, D.E.19
Chen, H.Y.20
Van der Ploeg, L.H.T.21
more..
-
28
-
-
18444375866
-
Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity
-
Chen Y, Hu C, Hsu CK, Zhang Q, Asnicar M, Hsiung HM, Slieker LJ, Yang DD, Helman ML, Shi Y. 2002. Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity. Endocrinology 143:2469-2477.
-
(2002)
Endocrinology
, vol.143
, pp. 2469-2477
-
-
Chen, Y.1
Hu, C.2
Hsu, C.K.3
Zhang, Q.4
Asnicar, M.5
Hsiung, H.M.6
Slieker, L.J.7
Yang, D.D.8
Helman, M.L.9
Shi, Y.10
-
29
-
-
2542475178
-
Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y (NPY) and agouti-related protein (AgRP)
-
Chen HY, Trumbauer ME, Chan AS, Wingarth DT, Adams JR, Frazier FG, Shan Z, Marsh DJ, Feighner SD, Guan XM, Ye Z, Nargund RP, Smith RG, Van de Ploeg LH, Howard AD, MacNeil DJ, Glan S. 2004. Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y (NPY) and agouti-related protein (AgRP). Endocrinology 145: 2607-2612.
-
(2004)
Endocrinology
, vol.145
, pp. 2607-2612
-
-
Chen, H.Y.1
Trumbauer, M.E.2
Chan, A.S.3
Wingarth, D.T.4
Adams, J.R.5
Frazier, F.G.6
Shan, Z.7
Marsh, D.J.8
Feighner, S.D.9
Guan, X.M.10
Ye, Z.11
Nargund, R.P.12
Smith, R.G.13
Van de Ploeg, L.H.14
Howard, A.D.15
MacNeil, D.J.16
Glan, S.17
-
30
-
-
0037373522
-
The role of ghrelin and growth hormone secretagogues receptor on rat adipogenesis
-
Choi K, Roh SG, Hong YH, Shrestha YB, Hishikawa D, Chen C, Kojima M, Kangawa K, Sasaki S. 2003. The role of ghrelin and growth hormone secretagogues receptor on rat adipogenesis. Endocrinology 144:754-759.
-
(2003)
Endocrinology
, vol.144
, pp. 754-759
-
-
Choi, K.1
Roh, S.G.2
Hong, Y.H.3
Shrestha, Y.B.4
Hishikawa, D.5
Chen, C.6
Kojima, M.7
Kangawa, K.8
Sasaki, S.9
-
31
-
-
0021248888
-
Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats
-
Clark JT, Kalra PS, Crowley WR, Kalra SP. 1984. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 115:427-429.
-
(1984)
Endocrinology
, vol.115
, pp. 427-429
-
-
Clark, J.T.1
Kalra, P.S.2
Crowley, W.R.3
Kalra, S.P.4
-
32
-
-
0034720023
-
Regulation of leptin by agouti
-
Claycombe KJ, Xue BZ, Mynatt RL, Zemel MB, Moustaid-Moussa N. 2000. Regulation of leptin by agouti. Physiol Genomics 27:101-105.
-
(2000)
Physiol. Genomics
, vol.27
, pp. 101-105
-
-
Claycombe, K.J.1
Xue, B.Z.2
Mynatt, R.L.3
Zemel, M.B.4
Moustaid-Moussa, N.5
-
33
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR. 1996. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. New Engl J Med 334:292-295.
-
(1996)
New Engl. J. Med.
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
-
34
-
-
0034880752
-
Pro-inflammatory cytokines and adipose tissue
-
Coppack SW. 2001. Pro-inflammatory cytokines and adipose tissue. Proc Nutr Soc 60:349-356.
-
(2001)
Proc. Nutr. Soc.
, vol.60
, pp. 349-356
-
-
Coppack, S.W.1
-
35
-
-
0034455660
-
Dissociation of locomotor activation and suppression of food intake induced by CRF in CRFR1-deficient mice
-
Contarino A, Dellu F, Koob GF, Smith GW, Lee KF, Vale WW, Gold LH. 2000. Dissociation of locomotor activation and suppression of food intake induced by CRF in CRFR1-deficient mice. Endocrinology 141:2698-2702.
-
(2000)
Endocrinology
, vol.141
, pp. 2698-2702
-
-
Contarino, A.1
Dellu, F.2
Koob, G.F.3
Smith, G.W.4
Lee, K.F.5
Vale, W.W.6
Gold, L.H.7
-
36
-
-
0034087469
-
Abnormal adaptation to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2
-
Coste SC, Kesterson RA, Heldwein KA, Stervens SL, Heard AD, Hollis IH, Murray SE, Hill JK, Pantely GA, Hohimer AR, Hatton AR, Hatton DC, Phillips TJ, Finn DA, Low MJ, Rittenberg MB, Stenzel F, Stenzel-Foor MF. 2000. Abnormal adaptation to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2. Nat Genet 24:403-409.
-
(2000)
Nat. Genet.
, vol.24
, pp. 403-409
-
-
Coste, S.C.1
Kesterson, R.A.2
Heldwein, K.A.3
Stervens, S.L.4
Heard, A.D.5
Hollis, I.H.6
Murray, S.E.7
Hill, J.K.8
Pantely, G.A.9
Hohimer, A.R.10
Hatton, A.R.11
Hatton, D.C.12
Phillips, T.J.13
Finn, D.A.14
Low, M.J.15
Rittenberg, M.B.16
Stenzel, F.17
Stenzel-Foor, M.F.18
-
37
-
-
85047690626
-
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
-
Cota D, Marsicano G, Tschop M, Grubler Y, Flachskamm C, Schubert M, Auer D, Yassourdis A, Thone-Reineke C, Ortmann S, Tomassoni F, Cervino C, Nisoli E, Linthorst AC, R, Lutz B, Stalla GK, Pagotto U. 2003 The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 112:423-431.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 423-431
-
-
Cota, D.1
Marsicano, G.2
Tschop, M.3
Grubler, Y.4
Flachskamm, C.5
Schubert, M.6
Auer, D.7
Yassourdis, A.8
Thone-Reineke, C.9
Ortmann, S.10
Tomassoni, F.11
Cervino, C.12
Nisoli, E.13
Linthorst, A.C.R.14
Lutz, B.15
Stalla, G.K.16
Pagotto, U.17
-
38
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley MA, Smart JL, Rubinstein M, Cerdan MG, Diano S, Horvath TL, Cone RD, Low MJ. 2001. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411:480-484.
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
Smart, J.L.2
Rubinstein, M.3
Cerdan, M.G.4
Diano, S.5
Horvath, T.L.6
Cone, R.D.7
Low, M.J.8
-
39
-
-
0037162116
-
Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery
-
Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, Purnell JG. 2002. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. New Engl J Med 346:1623-1630.
-
(2002)
New Engl. J. Med.
, vol.346
, pp. 1623-1630
-
-
Cummings, D.E.1
Weigle, D.S.2
Frayo, R.S.3
Breen, P.A.4
Ma, M.K.5
Dellinger, E.P.6
Purnell, J.G.7
-
40
-
-
0028922052
-
Effect of sustained physiological hyperinsulinemia on hypothalamic neuropeptide Y and NPY mRNA levels in the rat
-
Cusin I, Dryden S, Wang Q, Rohner-Jeanrenaud F, Jeanrenaud B, Williams G. 1995. Effect of sustained physiological hyperinsulinemia on hypothalamic neuropeptide Y and NPY mRNA levels in the rat. J Neuroendocrinol 7:193-197.
-
(1995)
J. Neuroendocrinol.
, vol.7
, pp. 193-197
-
-
Cusin, I.1
Dryden, S.2
Wang, Q.3
Rohner-Jeanrenaud, F.4
Jeanrenaud, B.5
Williams, G.6
-
41
-
-
2342453229
-
High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in pima Indians
-
De Courten BV, Degawa-Yamauchi M, Considine RV, Tataranni PA. 2004. High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in pima Indians. Diabetes 53:1279-1284.
-
(2004)
Diabetes
, vol.53
, pp. 1279-1284
-
-
De Courten, B.V.1
Degawa-Yamauchi, M.2
Considine, R.V.3
Tataranni, P.A.4
-
42
-
-
0008390266
-
The hypocretins; hypothalamic specific peptide with neuroexcitatory activity
-
De Lecea L, Kilduff TS, Peyrun C, Gao X, Foye PE, Danielson PE, Fukuhara C, Battenberg EL, Cautvik VT, Bartlett IIFS, Frankel WN, van den Pol AN, Bloom FE, Cautvik KM, Sutclift JG. 1998. The hypocretins; hypothalamic specific peptide with neuroexcitatory activity. Proc Nat Acad Sci USA 95:322-327.
-
(1998)
Proc. Nat. Acad. Sci. USA
, vol.95
, pp. 322-327
-
-
De Lecea, L.1
Kilduff, T.S.2
Peyrun, C.3
Gao, X.4
Foye, P.E.5
Danielson, P.E.6
Fukuhara, C.7
Battenberg, E.L.8
Cautvik, V.T.9
Bartlett, I.I.F.S.10
Frankel, W.N.11
van den Pol, A.N.12
Bloom, F.E.13
Cautvik, K.M.14
Sutclift, J.G.15
-
43
-
-
0344874247
-
Serum resistin (FIZZ3) protein is increased in obese humans
-
Degawa-Yamaguchi M, Rovenkark JE, Juliar BE, Watson W, Karr K, Jones R, Zhu G, Considine RV. 2003. Serum resistin (FIZZ3) protein is increased in obese humans. J Clin Endocrinol Metab 88:5452-6566.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 5452-6566
-
-
Degawa-Yamaguchi, M.1
Rovenkark, J.E.2
Juliar, B.E.3
Watson, W.4
Karr, K.5
Jones, R.6
Zhu, G.7
Considine, R.V.8
-
44
-
-
0141461415
-
Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
-
During MJ, Cao L, Zuzga DS, Francis JS, Fitsimons HL, Jiao X, Bland RJ, Klugmann M, Ganks WA, Drucker DJ, Haile CN. 2003. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nat Med 9:1173-1179.
-
(2003)
Nat. Med.
, vol.9
, pp. 1173-1179
-
-
During, M.J.1
Cao, L.2
Zuzga, D.S.3
Francis, J.S.4
Fitsimons, H.L.5
Jiao, X.6
Bland, R.J.7
Klugmann, M.8
Ganks, W.A.9
Drucker, D.J.10
Haile, C.N.11
-
45
-
-
0036075862
-
Food fails to suppress ghrelin levels in obese humans
-
English PJ, Ghatei MA, Malik IA, Bloom SR, Wilding JP. 2002. Food fails to suppress ghrelin levels in obese humans. J Clin Endocrinol Metab 87:2984-2987.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2984-2987
-
-
English, P.J.1
Ghatei, M.A.2
Malik, I.A.3
Bloom, S.R.4
Wilding, J.P.5
-
46
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
-
Erickson JC, Hollopeter G, Palmiter RD. 1996. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 274:1704-1707.
-
(1996)
Science
, vol.274
, pp. 1704-1707
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
47
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 rector gene
-
Farooqi IS, Keogh JM, Yeo GSH, Lank EJ, Cheetham T, O'Rahilly S. 2003. Clinical spectrum of obesity and mutations in the melanocortin 4 rector gene. New Engl J Med 348:1085-1103.
-
(2003)
New Engl. J. Med.
, vol.348
, pp. 1085-1103
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.H.3
Lank, E.J.4
Cheetham, T.5
O'Rahilly, S.6
-
48
-
-
0035044397
-
The melanocortin melanocyte-stimulating hormone/adrenocorticotropin 4-10 decreases body fat in humans
-
Fehm HL, Smolnik R, Kern W, McGregor GP, Bickel U, Born J. 2001. The melanocortin melanocyte-stimulating hormone/adrenocorticotropin 4-10 decreases body fat in humans. J Clin Endocrinol Metab 86:1144-1148.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1144-1148
-
-
Fehm, H.L.1
Smolnik, R.2
Kern, W.3
McGregor, G.P.4
Bickel, U.5
Born, J.6
-
49
-
-
0032548825
-
Obesity and the hypothalamus: Novel peptides for new pathways
-
Flier JS, Maratos-Flier E. 1998. Obesity and the hypothalamus: Novel peptides for new pathways. Cell 92:437-440.
-
(1998)
Cell
, vol.92
, pp. 437-440
-
-
Flier, J.S.1
Maratos-Flier, E.2
-
50
-
-
0038116319
-
Adipose tissue as an endocrine organ: Role of leptin and adiponectin in the pathogenesis of cardiovascular disease
-
Fortuno A, Rodriguez A, Gomez-Ambrosi J, Fruhbeck G, Diez J. 2003. Adipose tissue as an endocrine organ: Role of leptin and adiponectin in the pathogenesis of cardiovascular disease. J Physiol Biochem 59:51-60.
-
(2003)
J. Physiol. Biochem.
, vol.59
, pp. 51-60
-
-
Fortuno, A.1
Rodriguez, A.2
Gomez-Ambrosi, J.3
Fruhbeck, G.4
Diez, J.5
-
51
-
-
0031762908
-
Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid
-
Fried SK, Bunkin DA, Greenberg AS. 1998. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 83:847-850.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 847-850
-
-
Fried, S.K.1
Bunkin, D.A.2
Greenberg, A.S.3
-
52
-
-
0037238703
-
Modulation of 11 beta-hydroxysteroid dehydrogenase type 1 in mature human subcutaneous adipocytes by hypothalamic messengers
-
Friedberg M, Zoumakis E, Hiroi N, Barder T, Chrousos GP, Hochberg Z. 2003. Modulation of 11 beta-hydroxysteroid dehydrogenase type 1 in mature human subcutaneous adipocytes by hypothalamic messengers. J Clin Endocrinol Metab 88:385-393.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 385-393
-
-
Friedberg, M.1
Zoumakis, E.2
Hiroi, N.3
Barder, T.4
Chrousos, G.P.5
Hochberg, Z.6
-
53
-
-
0031587418
-
In vitro lipolytic effect of leptin on mouse adipocytes: Evidence for a possible autocrine/paracrine role of leptin
-
Fruhbeck G, Aguado M, Martinez JA. 1997. In vitro lipolytic effect of leptin on mouse adipocytes: Evidence for a possible autocrine/paracrine role of leptin. Biochem Biophys Res Commun 240:590-594.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.240
, pp. 590-594
-
-
Fruhbeck, G.1
Aguado, M.2
Martinez, J.A.3
-
54
-
-
10744229354
-
Enzyme-linked immunosorbent assay for circulating human resistin: Resistin concentrations in normal subjects and patients with type 2 diabetes
-
Fujinami A, Obayashi H, Ohta K, Ichimura T, Nishimura M, Matsui H, Kawahara Y, Yamazaki M, Ogata M, Hasegawa G, Nakamura N, Yoshikawa T, Nakano K, Ohta M. 2004. Enzyme-linked immunosorbent assay for circulating human resistin: Resistin concentrations in normal subjects and patients with type 2 diabetes. Clin Chim Acta 339:57-63.
-
(2004)
Clin. Chim. Acta
, vol.339
, pp. 57-63
-
-
Fujinami, A.1
Obayashi, H.2
Ohta, K.3
Ichimura, T.4
Nishimura, M.5
Matsui, H.6
Kawahara, Y.7
Yamazaki, M.8
Ogata, M.9
Hasegawa, G.10
Nakamura, N.11
Yoshikawa, T.12
Nakano, K.13
Ohta, M.14
-
55
-
-
0027480005
-
Hypersecretion of truncated glucagons-like peptide-1 and gastric inhibitory polypeptide in obese patients
-
Fukase N, Igarashi M, Takahashi H, Manaka H, Yamatani K, Daimon M, Tominaga M, Sasaki H. 1993. Hypersecretion of truncated glucagons-like peptide-1 and gastric inhibitory polypeptide in obese patients. Diabet Med 10:44-49.
-
(1993)
Diabet. Med.
, vol.10
, pp. 44-49
-
-
Fukase, N.1
Igarashi, M.2
Takahashi, H.3
Manaka, H.4
Yamatani, K.5
Daimon, M.6
Tominaga, M.7
Sasaki, H.8
-
56
-
-
0041704635
-
Co-expression of leptin- and orexin-receptors in feeding-regulating neurons in the hypothalamic arcuate nucleus- A triple labeling study
-
Funahashi H, Yamada S, Kageyama H, Takenoya F, Guan JL, Shioda S. 2003. Co-expression of leptin- and orexin-receptors in feeding-regulating neurons in the hypothalamic arcuate nucleus- a triple labeling study. Peptides 24:887-894.
-
(2003)
Peptides
, vol.24
, pp. 887-894
-
-
Funahashi, H.1
Yamada, S.2
Kageyama, H.3
Takenoya, F.4
Guan, J.L.5
Shioda, S.6
-
57
-
-
0034674764
-
Characterization of NPY receptors controlling lipolysis and leptin secretion in human adipocytes
-
Gal CS-L, Lafontan M, Raufaste D, Marchand J, Pouzet B, Casellas P, Pascal M, Maffrand J-P, Fur GL. 2000. Characterization of NPY receptors controlling lipolysis and leptin secretion in human adipocytes. FEBS Lett 475:150-156.
-
(2000)
FEBS Lett.
, vol.475
, pp. 150-156
-
-
Gal, C.S.-L.1
Lafontan, M.2
Raufaste, D.3
Marchand, J.4
Pouzet, B.5
Casellas, P.6
Pascal, M.7
Maffrand, J.-P.8
Fur, G.L.9
-
58
-
-
1842584949
-
Distribution of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermo dysregulation
-
Gao Q, Wolfgang MJ, Naschen S, Morino K, Horvath TL, Shulman GI, Fu XY. 2004. Distribution of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermo dysregulation. Proc Nat Acad Sci USA 101:4661-4666.
-
(2004)
Proc. Nat. Acad. Sci. USA
, vol.101
, pp. 4661-4666
-
-
Gao, Q.1
Wolfgang, M.J.2
Naschen, S.3
Morino, K.4
Horvath, T.L.5
Shulman, G.I.6
Fu, X.Y.7
-
59
-
-
0027214546
-
Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: Comparison with interleukin-1 family and interleukin-6
-
Gatti S, Bartfal T. 1993. Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: Comparison with interleukin-1 family and interleukin-6. Brain Res 624:291-294.
-
(1993)
Brain Res.
, vol.624
, pp. 291-294
-
-
Gatti, S.1
Bartfal, T.2
-
60
-
-
15844420659
-
A receptor subtype involved in neuropeptide-Y-induced food intake
-
Gerald C, Walker MW, Criscione L, Gustafson EL, Batzl-Hartmann C, Smith KE, Vaysse P, Dirkin MM, Laz TM, Linemeyer DL, Schaffhauser AO, Whitebread S, Hofbauer KG, Taber RI, Branchek TA, Weinshank RL. 1996. A receptor subtype involved in neuropeptide-Y-induced food intake. Nature 382:168-171.
-
(1996)
Nature
, vol.382
, pp. 168-171
-
-
Gerald, C.1
Walker, M.W.2
Criscione, L.3
Gustafson, E.L.4
Batzl-Hartmann, C.5
Smith, K.E.6
Vaysse, P.7
Dirkin, M.M.8
Laz, T.M.9
Linemeyer, D.L.10
Schaffhauser, A.O.11
Whitebread, S.12
Hofbauer, K.G.13
Taber, R.I.14
Branchek, T.A.15
Weinshank, R.L.16
-
61
-
-
1842840805
-
Brain insulin and feeding: A bi-directional communication
-
Gerozissis K. 2004. Brain insulin and feeding: A bi-directional communication. Eur J Pharmacol 490:59-70.
-
(2004)
Eur. J. Pharmacol.
, vol.490
, pp. 59-70
-
-
Gerozissis, K.1
-
62
-
-
3042735648
-
The tissue distribution of the mRNA of ghrelin and subtype of its receptor, GHS-R, in human
-
Gnanapavan S, Kola B, Bustin SA, Morris DG, McGee O, Fairclough P, Bhattacharys S, Carpenter R, Grossman AB, Korbonits M. 2002. The tissue distribution of the mRNA of ghrelin and subtype of its receptor, GHS-R, in human. J Clin Endocrinol Metab 87:2991.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2991
-
-
Gnanapavan, S.1
Kola, B.2
Bustin, S.A.3
Morris, D.G.4
McGee, O.5
Fairclough, P.6
Bhattacharys, S.7
Carpenter, R.8
Grossman, A.B.9
Korbonits, M.10
-
63
-
-
0037869116
-
Prospects for obesity treatment: MCH receptor antagonists
-
Gollins GA, Kym PR. 2003. Prospects for obesity treatment: MCH receptor antagonists. Curr Opin Invest Drugs 4:386-394.
-
(2003)
Curr. Opin. Invest. Drugs
, vol.4
, pp. 386-394
-
-
Gollins, G.A.1
Kym, P.R.2
-
64
-
-
0031280002
-
Overexpression of Agrp leads to obesity in transgenic mice
-
Graham M, Shutter JR, Sarmiento U, Sarosi I, Stark KI. 1997. Overexpression of Agrp leads to obesity in transgenic mice. Nat Genet 17:273-274.
-
(1997)
Nat. Genet.
, vol.17
, pp. 273-274
-
-
Graham, M.1
Shutter, J.R.2
Sarmiento, U.3
Sarosi, I.4
Stark, K.I.5
-
65
-
-
0028302002
-
Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase
-
Green A, Dobias SB, Walters DJ, Brasier AR. 1994. Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase. Endocrinology 134:2581-2588.
-
(1994)
Endocrinology
, vol.134
, pp. 2581-2588
-
-
Green, A.1
Dobias, S.B.2
Walters, D.J.3
Brasier, A.R.4
-
66
-
-
0031963436
-
Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus
-
Haekansson ML, Brown H, Chilardi N, Skoda RC, Meister B. 1998. Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus. J Neurosci 18:559-572.
-
(1998)
J. Neurosci.
, vol.18
, pp. 559-572
-
-
Haekansson, M.L.1
Brown, H.2
Chilardi, N.3
Skoda, R.C.4
Meister, B.5
-
68
-
-
0037086814
-
Anorectic thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice
-
Haynes AC, Chapman H, Taylor C, Moore GB, Cawthorne MA, Tadayyon M, Clapham JC, Arch JR. 2002. Anorectic thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice. Regul Pept 104:153-159.
-
(2002)
Regul. Pept.
, vol.104
, pp. 153-159
-
-
Haynes, A.C.1
Chapman, H.2
Taylor, C.3
Moore, G.B.4
Cawthorne, M.A.5
Tadayyon, M.6
Clapham, J.C.7
Arch, J.R.8
-
69
-
-
0027168223
-
Corticotropin-releasing factor in the paraventricular nucleus modulates feeding induced by neuropeptide Y
-
Heinrichs SC, Menzaghi F, Pich EM, Hauger RI, Koob GF. 1993. Corticotropin-releasing factor in the paraventricular nucleus modulates feeding induced by neuropeptide Y. Brain Res 611:18-24.
-
(1993)
Brain Res.
, vol.611
, pp. 18-24
-
-
Heinrichs, S.C.1
Menzaghi, F.2
Pich, E.M.3
Hauger, R.I.4
Koob, G.F.5
-
70
-
-
21044447326
-
Molecular cloning and functional characterization of MCH2, a novel human MCH receptor
-
Hill J, Duckworth M, Murdock P, Rennie G, Sabido-David C, Ames RS, Szekeres P, Wilson S, Bergsma DJ, Gloger IS, Levy DS, Chambers JK, Muir AI. 2012. Molecular cloning and functional characterization of MCH2, a novel human MCH receptor. J Biol Chem 276:5-20129.
-
(2012)
J. Biol. Chem.
, vol.276
, pp. 5-20129
-
-
Hill, J.1
Duckworth, M.2
Murdock, P.3
Rennie, G.4
Sabido-David, C.5
Ames, R.S.6
Szekeres, P.7
Wilson, S.8
Bergsma, D.J.9
Gloger, I.S.10
Levy, D.S.11
Chambers, J.K.12
Muir, A.I.13
-
71
-
-
85047691827
-
Endocannabinoids and the regulation of body fat: The smoke is clearing
-
Horvath TL. 2003. Endocannabinoids and the regulation of body fat: The smoke is clearing. J Clin Invest 112:323-326.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 323-326
-
-
Horvath, T.L.1
-
72
-
-
0033081871
-
Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: A novel circuit implicated in the metabolic and endocrine regulation
-
Horvath TL, Diano S, van den Pol NA. 1999. Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: A novel circuit implicated in the metabolic and endocrine regulation. J Neurosci 19:1072-1087.
-
(1999)
J. Neurosci.
, vol.19
, pp. 1072-1087
-
-
Horvath, T.L.1
Diano, S.2
van den Pol, N.A.3
-
73
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamistigli GS, Shargill NS, Spiegelman BM. 1993. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science 259:87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamistigli, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
74
-
-
0000432665
-
Human stresscopin and stresscopin-related peptide are selective ligands for type 2 corticotropin-releasing hormone receptor
-
Hsu SY, Hsuch AJ. 2001. Human stresscopin and stresscopin-related peptide are selective ligands for type 2 corticotropin-releasing hormone receptor. Nat Med 7:605-611.
-
(2001)
Nat. Med.
, vol.7
, pp. 605-611
-
-
Hsu, S.Y.1
Hsuch, A.J.2
-
75
-
-
0242413107
-
Adipocyte-selective reduction of the leptin receptors induced by antisense RNA leads to increased adiposity, dyslipidemia, and insulin resistance
-
Huan JN, Han Y, Chen K, Wu N, Zhao AZ. 2003. Adipocyte-selective reduction of the leptin receptors induced by antisense RNA leads to increased adiposity, dyslipidemia, and insulin resistance. J Biol Chem 278:45838-45850.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45838-45850
-
-
Huan, J.N.1
Han, Y.2
Chen, K.3
Wu, N.4
Zhao, A.Z.5
-
76
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeler LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F. 1997. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88:131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeler, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
77
-
-
0142074254
-
Plasma orexin-A levels in obstructive sleep apnea-hypopnea syndrome
-
Igarashi N, Tastumi K, Nakamura A, Sakao S, Takiguchi Y, Ichikawa T, Kuriyama T. 2003. Plasma orexin-A levels in obstructive sleep apnea-hypopnea syndrome. Chest 124:1381-1385.
-
(2003)
Chest
, vol.124
, pp. 1381-1385
-
-
Igarashi, N.1
Tastumi, K.2
Nakamura, A.3
Sakao, S.4
Takiguchi, Y.5
Ichikawa, T.6
Kuriyama, T.7
-
78
-
-
0034912638
-
Prepro-orexin and orexin receptor mRNA are differentially expressed in peripheral tissues of male and female rats
-
Johren O, Neidert SJ, Kummer M, Dendorfer A, Dominiak P. 2001. Prepro-orexin and orexin receptor mRNA are differentially expressed in peripheral tissues of male and female rats. Endocrinology 142:3324-3331.
-
(2001)
Endocrinology
, vol.142
, pp. 3324-3331
-
-
Johren, O.1
Neidert, S.J.2
Kummer, M.3
Dendorfer, A.4
Dominiak, P.5
-
79
-
-
0033857975
-
Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs
-
Kaiyala KJ, Prigeon RL, SE, Woods SC, Schwartz MW. 2000. Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs. Diabetes 49:1525-1533.
-
(2000)
Diabetes
, vol.49
, pp. 1525-1533
-
-
Kaiyala, K.J.1
Prigeon, R.L.S.E.2
Woods, S.C.3
Schwartz, M.W.4
-
80
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS. 1999. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20:68-100.
-
(1999)
Endocr. Rev.
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
Dube, M.G.2
Pu, S.3
Xu, B.4
Horvath, T.L.5
Kalra, P.S.6
-
81
-
-
0035125558
-
A typical Y1 receptor regulates feeding behaviors: Effects of a potent and selective Y1 antagonist, J-115814
-
Kanatani A, Hata M, Mashiko S, Ishihara A, Okamoto O, Haga Y, Ohe T, Kanno T, Murai N, Ishii Y, Fukuroda T, Fukami T, Ihara M. 2001. A typical Y1 receptor regulates feeding behaviors: Effects of a potent and selective Y1 antagonist, J-115814. Mol Pharmacol 59:501-505.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 501-505
-
-
Kanatani, A.1
Hata, M.2
Mashiko, S.3
Ishihara, A.4
Okamoto, O.5
Haga, Y.6
Ohe, T.7
Kanno, T.8
Murai, N.9
Ishii, Y.10
Fukuroda, T.11
Fukami, T.12
Ihara, M.13
-
82
-
-
0031786114
-
Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): Evaluation in vitro and in vivo
-
Kask A, Mutulis F, Muceniece R, Pahkla R, Mutule I, Wikberg JE, Rago L, Schloth HB. 1998. Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): Evaluation in vitro and in vivo. Endocrinology 139:5006-5014.
-
(1998)
Endocrinology
, vol.139
, pp. 5006-5014
-
-
Kask, A.1
Mutulis, F.2
Muceniece, R.3
Pahkla, R.4
Mutule, I.5
Wikberg, J.E.6
Rago, L.7
Schloth, H.B.8
-
83
-
-
0032943465
-
Orexin A but not orexin B rapidly enters brain from blood by simple diffusion
-
Kastin AJ, Akerstrom V. 1999. Orexin A but not orexin B rapidly enters brain from blood by simple diffusion. J Pharmacol Exp Ther 289:219-223.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 219-223
-
-
Kastin, A.J.1
Akerstrom, V.2
-
84
-
-
17744396287
-
Plasma levels of agouti-related protein are increased in obese men
-
Katsuki A, Sumida Y, Gabazza EV, Murahashi S, Tanaka T, Furuta M, Araki-Sasaki T, Hori Y, Nakatani K, Yano Y, Adachi Y. 2001. Plasma levels of agouti-related protein are increased in obese men. J Clin Endocrinol Metab 86:1921-1924.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1921-1924
-
-
Katsuki, A.1
Sumida, Y.2
Gabazza, E.V.3
Murahashi, S.4
Tanaka, T.5
Furuta, M.6
Araki-Sasaki, T.7
Hori, Y.8
Nakatani, K.9
Yano, Y.10
Adachi, Y.11
-
85
-
-
15644362064
-
Serum levels of tumor necrosis factor-alpha are increased in obese patients with noninsulin-dependent diabetes mellitus
-
Katsuki A, Sumida Y, Murashima S, Murata K, Takarada Y, Ito K, Fujii N, Tsuchihashi K, Goto H, Nakatani K, Yano Y. 1998. Serum levels of tumor necrosis factor-alpha are increased in obese patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 83:859-862.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 859-862
-
-
Katsuki, A.1
Sumida, Y.2
Murashima, S.3
Murata, K.4
Takarada, Y.5
Ito, K.6
Fujii, N.7
Tsuchihashi, K.8
Goto, H.9
Nakatani, K.10
Yano, Y.11
-
86
-
-
0033770186
-
Elevated plasma levels of alpha-melanocyte stimulating hormone (alpha-MSH) are correlated with insulin resistance in obese men
-
Katsuki A, Sumida Y, Murashima S, Furuta M, Araki-Sasaki R, Tsuchihashi K, Hori Y, Yano Y, Adachi Y. 2000. Elevated plasma levels of alpha-melanocyte stimulating hormone (alpha-MSH) are correlated with insulin resistance in obese men. Int J Obes Relat Metab Disord 24:1260-1264.
-
(2000)
Int. J. Obes. Relat. Metab. Disord.
, vol.24
, pp. 1260-1264
-
-
Katsuki, A.1
Sumida, Y.2
Murashima, S.3
Furuta, M.4
Araki-Sasaki, R.5
Tsuchihashi, K.6
Hori, Y.7
Yano, Y.8
Adachi, Y.9
-
87
-
-
0035023128
-
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
-
Kern PA, Ranganathan S, Ki C, Wood L, Ranganathan G. 2001. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 280:E745-E751.
-
(2001)
Am. J. Physiol. Endocrinol. Metab.
, vol.280
-
-
Kern, P.A.1
Ranganathan, S.2
Ki, C.3
Wood, L.4
Ranganathan, G.5
-
88
-
-
0000573907
-
Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone
-
Kim MS, Rossi M, Abusnana S, Sunter D, Morgan DGA, Small CJ, Edwards CMB, Heath MM, Stanley SA, Seal LJ, Ghatti JR, Smith DM, Ghatei MA, Bloom SR. 2000. Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone. Diabetes 49: 177-182.
-
(2000)
Diabetes
, vol.49
, pp. 177-182
-
-
Kim, M.S.1
Rossi, M.2
Abusnana, S.3
Sunter, D.4
Morgan, D.G.A.5
Small, C.J.6
Edwards, C.M.B.7
Heath, M.M.8
Stanley, S.A.9
Seal, L.J.10
Ghatti, J.R.11
Smith, D.M.12
Ghatei, M.A.13
Bloom, S.R.14
-
89
-
-
0031454125
-
Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes
-
Kirchgessner TG, Uysal KT, Wiesbrock SM, Marino MW, Totamisligil GS. 1997. Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. J Clin Invest 100:2777-2782.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2777-2782
-
-
Kirchgessner, T.G.1
Uysal, K.T.2
Wiesbrock, S.M.3
Marino, M.W.4
Totamisligil, G.S.5
-
90
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M, Hosoda H, Date Y, Nakazato M, Mtsuo H, Kangawa K. 1999. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:658-660.
-
(1999)
Nature
, vol.402
, pp. 658-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Mtsuo, H.5
Kangawa, K.6
-
91
-
-
0032417697
-
Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice
-
Kushi A, Sasai H, Koizumi H, Takeda N, Yokoyama M, Nakamura M. 1998. Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice. Proc Nat Acad Sci USA 95:15659-15664.
-
(1998)
Proc. Nat. Acad. Sci. USA
, vol.95
, pp. 15659-15664
-
-
Kushi, A.1
Sasai, H.2
Koizumi, H.3
Takeda, N.4
Yokoyama, M.5
Nakamura, M.6
-
92
-
-
0030967436
-
Central administration of glucagons-like peptide-1 activates hypothalamic neuroendocrine neurons in the rat
-
Larsen PJ, Tang-Christensen M, Jessop D. 1997. Central administration of glucagons-like peptide-1 activates hypothalamic neuroendocrine neurons in the rat. Endocrinology 138:4445-4455.
-
(1997)
Endocrinology
, vol.138
, pp. 4445-4455
-
-
Larsen, P.J.1
Tang-Christensen, M.2
Jessop, D.3
-
93
-
-
0035516188
-
Systemic administration of the long-acting GLP-1 derivative NM2211 induces lasting and reversible weight loss in both normal and obese rats
-
Larsen PJ, Fledelius C, Knudsen LB, Tang-Christensen M. 2001. Systemic administration of the long-acting GLP-1 derivative NM2211 induces lasting and reversible weight loss in both normal and obese rats. Diabetes 50:2530-2539.
-
(2001)
Diabetes
, vol.50
, pp. 2530-2539
-
-
Larsen, P.J.1
Fledelius, C.2
Knudsen, L.B.3
Tang-Christensen, M.4
-
94
-
-
0042767613
-
Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats
-
Li G, Mobbs CV, Scarpace PJ. 2003. Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats. Diabetes 52:1951-1957.
-
(2003)
Diabetes
, vol.52
, pp. 1951-1957
-
-
Li, G.1
Mobbs, C.V.2
Scarpace, P.J.3
-
95
-
-
0037031088
-
Adiponectin and development of type 2 diabetes in the Pima Indian population
-
Lindsay RS, Funahashi T, Hanson RI, Matsuzawa Y, Tanaka S, Tataranni PA, Knowler WC, Krakoff J. 2002. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 360:57-58.
-
(2002)
Lancet
, vol.360
, pp. 57-58
-
-
Lindsay, R.S.1
Funahashi, T.2
Hanson, R.I.3
Matsuzawa, Y.4
Tanaka, S.5
Tataranni, P.A.6
Knowler, W.C.7
Krakoff, J.8
-
96
-
-
0028112970
-
Agouti protein is an antagonist of the melanocyte-stimulating hormone receptor
-
Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T, Luther M, Chen W, Woychik RF, Wilkitson WO, Cone RD. 1994. Agouti protein is an antagonist of the melanocyte-stimulating hormone receptor. Nature 371:799-802.
-
(1994)
Nature
, vol.371
, pp. 799-802
-
-
Lu, D.1
Willard, D.2
Patel, I.R.3
Kadwell, S.4
Overton, L.5
Kost, T.6
Luther, M.7
Chen, W.8
Woychik, R.F.9
Wilkitson, W.O.10
Cone, R.D.11
-
97
-
-
0033921449
-
Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting
-
Lu XY, Bagnil D, Burks S, Akil H, Watson SJ. 2000. Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting. Horm Behav 37:335-344.
-
(2000)
Horm. Behav.
, vol.37
, pp. 335-344
-
-
Lu, X.Y.1
Bagnil, D.2
Burks, S.3
Akil, H.4
Watson, S.J.5
-
98
-
-
0035134670
-
Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance
-
Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E. 2001. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest 107: 379-386.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 379-386
-
-
Ludwig, D.S.1
Tritos, N.A.2
Mastaitis, J.W.3
Kulkarni, R.4
Kokkotou, E.5
Elmquist, J.6
Lowell, B.7
Flier, J.S.8
Maratos-Flier, E.9
-
99
-
-
0036090282
-
Increased resistin gene and protein expression in human abdominal adipose tissue
-
McTernan PG, McTernan CL, Cherry R, Jenner K, M FM, Lauer MN, Crocker J, Barnett AH, Kumar S. 2002. Increased resistin gene and protein expression in human abdominal adipose tissue. J Clin Endocrinol Metab 87:2407-2410.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2407-2410
-
-
McTernan, P.G.1
McTernan, C.L.2
Cherry, R.3
Jenner, K.M.F.M.4
Lauer, M.N.5
Crocker, J.6
Barnett, A.H.7
Kumar, S.8
-
100
-
-
0036063777
-
Diet-induced insulin resistance in mice lacking adiponenctin/ACRP30
-
Maeda N, Shimomura I, Kishida K, Nishizawa H, Matsuda M, Nagaretani H, Furuyama N, Kondo H, Takahashi M, Arita Y, Komuro R, Ouchi N, Kihara S, Tochino Y, Okutomi K, Horie M, Takeda S, Aoyama T, Funahashi T, Matsuzawa Y. 2002. Diet-induced insulin resistance in mice lacking adiponenctin/ACRP30. Nat Med 8:731-737.
-
(2002)
Nat. Med.
, vol.8
, pp. 731-737
-
-
Maeda, N.1
Shimomura, I.2
Kishida, K.3
Nishizawa, H.4
Matsuda, M.5
Nagaretani, H.6
Furuyama, N.7
Kondo, H.8
Takahashi, M.9
Arita, Y.10
Komuro, R.11
Ouchi, N.12
Kihara, S.13
Tochino, Y.14
Okutomi, K.15
Horie, M.16
Takeda, S.17
Aoyama, T.18
Funahashi, T.19
Matsuzawa, Y.20
more..
-
101
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kern PA, Friedman JM. 1995. Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161.
-
(1995)
Nat. Med.
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
Fei, H.7
Kim, S.8
Lallone, R.9
Ranganathan, S.10
Kern, P.A.11
Friedman, J.M.12
-
102
-
-
0037022667
-
Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism
-
Marsh DJ, Weingarth DT, Novi DE, Chen HY, Trumbauer ME, Chen AS, Guan XM, Jiang MM, Feng Y, Camacho RE, Shen Z, Frazier EG, Yu H, Metzger JM, Kuca SJ, Shearman LP, Gopal-Truter S, MacNell DJ, Strack AM, MacIntyre DE, Van der Ploeg LH, Qian S. 2002. Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism. Proc Nat Acad Sci USA 99:3240-3245.
-
(2002)
Proc. Nat. Acad. Sci. USA
, vol.99
, pp. 3240-3245
-
-
Marsh, D.J.1
Weingarth, D.T.2
Novi, D.E.3
Chen, H.Y.4
Trumbauer, M.E.5
Chen, A.S.6
Guan, X.M.7
Jiang, M.M.8
Feng, Y.9
Camacho, R.E.10
Shen, Z.11
Frazier, E.G.12
Yu, H.13
Metzger, J.M.14
Kuca, S.J.15
Shearman, L.P.16
Gopal-Truter, S.17
MacNell, D.J.18
Strack, A.M.19
MacIntyre, D.E.20
Van der Ploeg, L.H.21
Qian, S.22
more..
-
103
-
-
0042320948
-
y/a) obese mice
-
y/a) obese mice. Diabetes 52:2266-2273.
-
(2003)
Diabetes
, vol.52
, pp. 2266-2273
-
-
Masaki, T.1
Chiba, S.2
Yasuda, T.3
Tsubone, T.4
Kakuma, T.5
Shimomura, I.6
Funahashi, T.7
Matsuzawa, Y.8
Yoshimatsu, H.9
-
104
-
-
4644227974
-
Obesity in insulin receptor substrate-2-deficient mice: Disrupted control of arcuate nucleus neuropeptides
-
Masaki T, Chiba S, Noguchi H, Yasuda T, Tobe K, Suzuki R, Kadowaki T, Yoshimatsu H. 2004. Obesity in insulin receptor substrate-2-deficient mice: Disrupted control of arcuate nucleus neuropeptides. Obes Res 12:878-885.
-
(2004)
Obes. Res.
, vol.12
, pp. 878-885
-
-
Masaki, T.1
Chiba, S.2
Noguchi, H.3
Yasuda, T.4
Tobe, K.5
Suzuki, R.6
Kadowaki, T.7
Yoshimatsu, H.8
-
105
-
-
0035824440
-
A transgenic model of visceral obesity and the metabolic syndrome
-
Masuzaki H, Paterson J, Shinyama H, Morton NM, Multins JJ, Seckl JR, Flier JS. 2001. A transgenic model of visceral obesity and the metabolic syndrome. Science 294:2166-2170.
-
(2001)
Science
, vol.294
, pp. 2166-2170
-
-
Masuzaki, H.1
Paterson, J.2
Shinyama, H.3
Morton, N.M.4
Multins, J.J.5
Seckl, J.R.6
Flier, J.S.7
-
106
-
-
2342586061
-
The adipocyte as an endocrine cell
-
Miner JL. 2004. The adipocyte as an endocrine cell. J Anim Sci 82:936-941.
-
(2004)
J. Anim. Sci.
-
-
Miner, J.L.1
-
107
-
-
0033373619
-
Production of soluble tumor necrosis factor receptors by human subcutaneous adipose tissue in vivo
-
Mohamed Ali V, Goodrick S, Bulmer K, Holly JM, Yudkin JS, Coppack SW. 1999. Production of soluble tumor necrosis factor receptors by human subcutaneous adipose tissue in vivo. Am J Physiol Endocrinol Metab 277:E971-E975.
-
(1999)
Am. J. Physiol. Endocrinol. Metab.
, vol.277
-
-
Mohamed Ali, V.1
Goodrick, S.2
Bulmer, K.3
Holly, J.M.4
Yudkin, J.S.5
Coppack, S.W.6
-
108
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Aee A, Xue B, Mu J, Foufelle F, Ferre P, Birnbaum MJ, Stuck BJ, Kahn BB. 2004. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428:569-574.
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
Kim, Y.B.4
Aee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
Stuck, B.J.11
Kahn, B.B.12
-
111
-
-
0034806403
-
Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle
-
Nagaev I, Smith U. 2001. Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle. Biochem Biophys Res Commun 285:561-563.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.285
, pp. 561-563
-
-
Nagaev, I.1
Smith, U.2
-
112
-
-
0035843183
-
A role for ghrelin in the central regulation of feeding
-
Nakazato M, Murakami N, Date Y, Kojima M, Matsuo H, Kangawa K, Matsukura S. 2001. A role for ghrelin in the central regulation of feeding. Nature 409:194-198.
-
(2001)
Nature
, vol.409
, pp. 194-198
-
-
Nakazato, M.1
Murakami, N.2
Date, Y.3
Kojima, M.4
Matsuo, H.5
Kangawa, K.6
Matsukura, S.7
-
113
-
-
0034750667
-
Cerebrospinal fluid and plasma concentrations of leptin, NPY, and alpha-MSH in obese women and their relationship to negative energy balance
-
Nam SY, Kratzsch J, Kim KW, Kim KR, Lim SK, Marcus C. 2001. Cerebrospinal fluid and plasma concentrations of leptin, NPY, and alpha-MSH in obese women and their relationship to negative energy balance. J Clin Endocrinol Metab 86: 4849-4853.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 4849-4853
-
-
Nam, S.Y.1
Kratzsch, J.2
Kim, K.W.3
Kim, K.R.4
Lim, S.K.5
Marcus, C.6
-
114
-
-
0037469699
-
ACTH and alpha-MSH inhibit leptin expression and secretion in 3T3-L1 adipocytes: Model for a central-peripheral melanocortin-leptin pathway
-
Norman D, Isidori AM, Frajese V, Caprio M, Chew SL, Grossman AB, Clark AJ, Michael Besser G, Fabbri A. 2003. ACTH and alpha-MSH inhibit leptin expression and secretion in 3T3-L1 adipocytes: Model for a central-peripheral melanocortin-leptin pathway. Mol Cell Endocrinol 200:99-109.
-
(2003)
Mol. Cell Endocrinol.
, vol.200
, pp. 99-109
-
-
Norman, D.1
Isidori, A.M.2
Frajese, V.3
Caprio, M.4
Chew, S.L.5
Grossman, A.B.6
Clark, A.J.7
Michael Besser, G.8
Fabbri, A.9
-
115
-
-
0037146881
-
Effect of chronic administration of a CRF(1) receptor antagonist, CRA1000, on locomotor activity and endocrine responses to stress
-
Ohata H, Arai K, Shibasaki T. 2002. Effect of chronic administration of a CRF(1) receptor antagonist, CRA1000, on locomotor activity and endocrine responses to stress. European Journal of Pharmacology 457:201-206.
-
(2002)
European Journal of Pharmacology
, vol.457
, pp. 201-206
-
-
Ohata, H.1
Arai, K.2
Shibasaki, T.3
-
116
-
-
4043106461
-
Transgenic rescue of insulin receptor-deficient mice
-
Okamoto H, Nakae J, Kitamura T, Park BC, Dragatsis I, Accili D. 2004. Transgenic rescue of insulin receptor-deficient mice. J Clin Invest 114:214-223.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 214-223
-
-
Okamoto, H.1
Nakae, J.2
Kitamura, T.3
Park, B.C.4
Dragatsis, I.5
Accili, D.6
-
117
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann MM, Wilson BD, Yang YK, Kerns JA, Chen Y, Gantz I, Barsg GS. 1997. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278:135-138.
-
(1997)
Science
, vol.278
, pp. 135-138
-
-
Ollmann, M.M.1
Wilson, B.D.2
Yang, Y.K.3
Kerns, J.A.4
Chen, Y.5
Gantz, I.6
Barsg, G.S.7
-
118
-
-
0035016791
-
Human breast adipocytes express interleukin-6 (IL-6) and its receptor system: Increased IL-6 production by beta-adrenergic activation and effects of IL-6 on adipocyte function
-
Path G, Bornstein SR, Gurniak M, Chrousos GP, Scherbaum WA, Hauner H. 2001. Human breast adipocytes express interleukin-6 (IL-6) and its receptor system: Increased IL-6 production by beta-adrenergic activation and effects of IL-6 on adipocyte function. J Clin Endocrinol Metab 86:2281-2288.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 2281-2288
-
-
Path, G.1
Bornstein, S.R.2
Gurniak, M.3
Chrousos, G.P.4
Scherbaum, W.A.5
Hauner, H.6
-
119
-
-
0031779479
-
Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor
-
Pedrazzani T, Seydoux J, Kunstner P, Aubert JF, Grouzmann E, Beermann F, Brunner HR. 1998. Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor. Nat Med 4:722-726.
-
(1998)
Nat. Med.
, vol.4
, pp. 722-726
-
-
Pedrazzani, T.1
Seydoux, J.2
Kunstner, P.3
Aubert, J.F.4
Grouzmann, E.5
Beermann, F.6
Brunner, H.R.7
-
120
-
-
0036312394
-
Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesity
-
Pierroz DD, Ziotopoulou M, Ungsunan L, Moschos S, Flier JS, Mantzoros CS. 2002. Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesity. Diabetes 51:1337-1345.
-
(2002)
Diabetes
, vol.51
, pp. 1337-1345
-
-
Pierroz, D.D.1
Ziotopoulou, M.2
Ungsunan, L.3
Moschos, S.4
Flier, J.S.5
Mantzoros, C.S.6
-
121
-
-
0242364736
-
Body mass index influences plasma concentration of neuropeptide Y in healthy female volunteers: A pilot study
-
Pohl A, Nordin C. 2003. Body mass index influences plasma concentration of neuropeptide Y in healthy female volunteers: A pilot study. Gynecol Endocrinol 17:409-412.
-
(2003)
Gynecol. Endocrinol.
, vol.17
, pp. 409-412
-
-
Pohl, A.1
Nordin, C.2
-
122
-
-
0030033544
-
Melanin-concentrating hormone is a potent anorectic peptide regulated by food-deprivation and glucopenia in the rat
-
Presse F, Sorokovsky I, Max JF, Nicolaidis S, Nahon JL. 1996. Melanin-concentrating hormone is a potent anorectic peptide regulated by food-deprivation and glucopenia in the rat. Neuroscience 71:735-745.
-
(1996)
Neuroscience
, vol.71
, pp. 735-745
-
-
Presse, F.1
Sorokovsky, I.2
Max, J.F.3
Nicolaidis, S.4
Nahon, J.L.5
-
123
-
-
2442659256
-
Adiponenctin acts in the brain to decrease body weight
-
Qi Y, Takahashi N, Hileman SM, Patel HR, Berg AH, Pajvani UB, Scherer PE, Ahima RS. 2004. Adiponenctin acts in the brain to decrease body weight. Nat Med 11:524-529.
-
(2004)
Nat. Med.
, vol.11
, pp. 524-529
-
-
Qi, Y.1
Takahashi, N.2
Hileman, S.M.3
Patel, H.R.4
Berg, A.H.5
Pajvani, U.B.6
Scherer, P.E.7
Ahima, R.S.8
-
124
-
-
0036288345
-
Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice
-
Qian S, Chen H, Waingarth D, Trumbauer ME, Novi DE, Guan X, Yu H, Shan Z, Fang Y, Frazier E, Chen A, Camacho RE, Shearman LP, Gopal-Truter S, MacNeil DJ, Van der Ploeg LH, Marsh DJ. 2002. Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice. Mol Cell Biol 22:5027-5035.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 5027-5035
-
-
Qian, S.1
Chen, H.2
Waingarth, D.3
Trumbauer, M.E.4
Novi, D.E.5
Guan, X.6
Yu, H.7
Shan, Z.8
Fang, Y.9
Frazier, E.10
Chen, A.11
Camacho, R.E.12
Shearman, L.P.13
Gopal-Truter, S.14
MacNeil, D.J.15
Van der Ploeg, L.H.16
Marsh, D.J.17
-
125
-
-
13344279395
-
A role for melanin-concentrating hormone in the central regulation of feeding behavior
-
Qu D, Ludwig DS, Gammeltoft S, Piper M, Pelleymounter MA, Cullen MJ, Mathes WF, Przypek R, Kanarek R, Maratos-Flier E. 1996. A role for melanin-concentrating hormone in the central regulation of feeding behavior. Nature 380:243-247.
-
(1996)
Nature
, vol.380
, pp. 243-247
-
-
Qu, D.1
Ludwig, D.S.2
Gammeltoft, S.3
Piper, M.4
Pelleymounter, M.A.5
Cullen, M.J.6
Mathes, W.F.7
Przypek, R.8
Kanarek, R.9
Maratos-Flier, E.10
-
126
-
-
0030055478
-
Attenuated GLP-1 secretion in obesity: Cause or consequence?
-
Ranganath LR, Beely JM, Morgan LM, Wright JW, Howland R, Marks V. 1996. Attenuated GLP-1 secretion in obesity: Cause or consequence? Gut 38:916-919.
-
(1996)
Gut
, vol.38
, pp. 916-919
-
-
Ranganath, L.R.1
Beely, J.M.2
Morgan, L.M.3
Wright, J.W.4
Howland, R.5
Marks, V.6
-
127
-
-
0346458786
-
Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression
-
Raposinho PD, Padrazzini T, White RB, Palmitar RD, Aubart ML. 2004. Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. Endocrinology 145:304-310.
-
(2004)
Endocrinology
, vol.145
, pp. 304-310
-
-
Raposinho, P.D.1
Padrazzini, T.2
White, R.B.3
Palmitar, R.D.4
Aubart, M.L.5
-
128
-
-
0038306907
-
Insulin resistance/compensatory hyperinsulinemia, essential hypertension, and cardiovascular disease
-
Reaven GM. 2003. Insulin resistance/compensatory hyperinsulinemia, essential hypertension, and cardiovascular disease. J Clin Endocrinol Metab 88:2399-2403.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 2399-2403
-
-
Reaven, G.M.1
-
129
-
-
0034813242
-
Increased hypothalamic expression of the p78 tumor necrosis factor receptor in New Zealand obese mice
-
Risk NM, Joost HG, Eckal J. 2001. Increased hypothalamic expression of the p78 tumor necrosis factor receptor in New Zealand obese mice. Horm Metab Res 33:520-524.
-
(2001)
Horm. Metab. Res.
, vol.33
, pp. 520-524
-
-
Risk, N.M.1
Joost, H.G.2
Eckal, J.3
-
130
-
-
0031023301
-
Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight
-
Rossi M, Choi SJ, O'Shea D, Miyoshi T, Ghatei MA, Bloom SR. 1997. Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight. Endocrinology 138:351-355.
-
(1997)
Endocrinology
, vol.138
, pp. 351-355
-
-
Rossi, M.1
Choi, S.J.2
O'Shea, D.3
Miyoshi, T.4
Ghatei, M.A.5
Bloom, S.R.6
-
131
-
-
0036313033
-
Tumor necrosis factor-α suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: Nuclear factor-κB activation by TNF-α is obligatory
-
Ruan H, Harcohen N, Golub TR, Parijs LV, Lodish HF. 2002. Tumor necrosis factor-α suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: Nuclear factor-κB activation by TNF-α is obligatory. Diabetes 51:1319-1336.
-
(2002)
Diabetes
, vol.51
, pp. 1319-1336
-
-
Ruan, H.1
Harcohen, N.2
Golub, T.R.3
Parijs, L.V.4
Lodish, H.F.5
-
132
-
-
0028884712
-
Insulin and insulin-like growth factor II suppress neuropeptide Y release from the nerve terminals in the paraventricular nucleus: A putative hypothalamic site for energy homeostasis
-
Sahu A, Dube MG, Phelps CP, Sninsky CA, Kalra PS, Kalra SP. 1995. Insulin and insulin-like growth factor II suppress neuropeptide Y release from the nerve terminals in the paraventricular nucleus: A putative hypothalamic site for energy homeostasis. Endocrinology 136:5718-5724.
-
(1995)
Endocrinology
, vol.136
, pp. 5718-5724
-
-
Sahu, A.1
Dube, M.G.2
Phelps, C.P.3
Sninsky, C.A.4
Kalra, P.S.5
Kalra, S.P.6
-
133
-
-
0023759108
-
Evidence that NPY-containing neurons in the brain stem project into selected hypothalamic nuclei: Implication in feeding behavior
-
Sahu A, Kalra SF, Crowley WR, Kaira PS. 1988. Evidence that NPY-containing neurons in the brain stem project into selected hypothalamic nuclei: Implication in feeding behavior. Brain Res 457:376-378.
-
(1988)
Brain Res.
, vol.457
, pp. 376-378
-
-
Sahu, A.1
Kalra, S.F.2
Crowley, W.R.3
Kaira, P.S.4
-
134
-
-
0037173035
-
Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice
-
Sainsbury A, Scwarzer C, Couzens M, Fetissov S, Furtinger S, Jankin A, Cox HM, Sperk G, Hokfelt T, Herzog H. 2002. Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice. Proc Nat Acad Sci USA 99:8938-8943.
-
(2002)
Proc. Nat. Acad. Sci. USA
, vol.99
, pp. 8938-8943
-
-
Sainsbury, A.1
Scwarzer, C.2
Couzens, M.3
Fetissov, S.4
Furtinger, S.5
Jankin, A.6
Cox, H.M.7
Sperk, G.8
Hokfelt, T.9
Herzog, H.10
-
135
-
-
0033566084
-
Molecular characterization of the Melanin-concentrating hormone receptor
-
Saito Y, Nothacker HP, Wang Z, Lin SH, Leslie F, Civelli O. 1999. Molecular characterization of the Melanin-concentrating hormone receptor. Nature 400:265-269.
-
(1999)
Nature
, vol.400
, pp. 265-269
-
-
Saito, Y.1
Nothacker, H.P.2
Wang, Z.3
Lin, S.H.4
Leslie, F.5
Civelli, O.6
-
136
-
-
20244380014
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulates feeding behavior
-
Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GF, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Eishourbagy NA, Bergama DJ, Yanagisawa M. 1998. Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulates feeding behavior. Cell 92:573-585.
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
Amemiya, A.2
Ishii, M.3
Matsuzaki, I.4
Chemelli, R.M.5
Tanaka, H.6
Williams, S.C.7
Richardson, J.A.8
Kozlowski, G.F.9
Wilson, S.10
Arch, J.R.11
Buckingham, R.E.12
Haynes, A.C.13
Carr, S.A.14
Annan, R.S.15
McNulty, D.E.16
Liu, W.S.17
Terrett, J.A.18
Eishourbagy, N.A.19
Bergama, D.J.20
Yanagisawa, M.21
more..
-
137
-
-
13344280346
-
Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
-
Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D Jr., Woods SC, Seeley RJ, Weigle DS. 1996. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45:531-535.
-
(1996)
Diabetes
, vol.45
, pp. 531-535
-
-
Schwartz, M.W.1
Baskin, D.G.2
Bukowski, T.R.3
Kuijper, J.L.4
Foster, D.5
Lasser, G.6
Prunkard, D.E.7
Porte Jr., D.8
Woods, S.C.9
Seeley, R.J.10
Weigle, D.S.11
-
138
-
-
0029958404
-
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide-1 receptor gene
-
Scrocchi LA, Brown TJ, MacLusky N, Brubaker PL, Auerbach AB, Joyner AL, Drucker DJ. 1996. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide-1 receptor gene. Nat Med 2:1254-1258.
-
(1996)
Nat. Med.
, vol.2
, pp. 1254-1258
-
-
Scrocchi, L.A.1
Brown, T.J.2
MacLusky, N.3
Brubaker, P.L.4
Auerbach, A.B.5
Joyner, A.L.6
Drucker, D.J.7
-
139
-
-
1442303287
-
Corticotropin-releasing hormone system in human adipose tissue
-
Seres J, Bornstein SR, Seres P, Willenberg HS, Schutle KM, Scherbaum WA, Ehrart-Bornstein M. 2004. Corticotropin-releasing hormone system in human adipose tissue. J Clin Endocrinol Metab 89:965-970.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 965-970
-
-
Seres, J.1
Bornstein, S.R.2
Seres, P.3
Willenberg, H.S.4
Schutle, K.M.5
Scherbaum, W.A.6
Ehrart-Bornstein, M.7
-
140
-
-
18244391222
-
Plasma ghrelin levels in lean and obese humans and effect of glucose on ghrelin secretion
-
Shiiya T, Nakazato M, Mizuta M, Date Y, Mondai MS, Tanaka M, Nozoe S, Hosoda H, Kangawa K, Matsukura S. 2002. Plasma ghrelin levels in lean and obese humans and effect of glucose on ghrelin secretion. J Clin Endocrinol Metab 87: 240-244.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 240-244
-
-
Shiiya, T.1
Nakazato, M.2
Mizuta, M.3
Date, Y.4
Mondai, M.S.5
Tanaka, M.6
Nozoe, S.7
Hosoda, H.8
Kangawa, K.9
Matsukura, S.10
-
141
-
-
0032542294
-
Mice lacking melanin-concentrating hormone are hypophagic and lean
-
Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E. 1998. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396:670-674.
-
(1998)
Nature
, vol.396
, pp. 670-674
-
-
Shimada, M.1
Tritos, N.A.2
Lowell, B.B.3
Flier, J.S.4
Maratos-Flier, E.5
-
142
-
-
0030968145
-
Serum leptin concentration is associated with total body fat mass, but not abdominal fat distribution
-
Shimizu H, Shimomura Y, Hayashi R, Ohtani K, Sato N, Futawatari T, Mori M. 1997. Serum leptin concentration is associated with total body fat mass, but not abdominal fat distribution. Int J Obes Relat Metab Disord 21:536-541.
-
(1997)
Int. J. Obes. Relat. Metab. Disord.
, vol.21
, pp. 536-541
-
-
Shimizu, H.1
Shimomura, Y.2
Hayashi, R.3
Ohtani, K.4
Sato, N.5
Futawatari, T.6
Mori, M.7
-
143
-
-
0036310223
-
Attenuation of diabetic hyperphagia in neuropeptide Y-deficient mice
-
Sindelar DR, Mystkowski P, Marsh DJ, Palmiter RD, Schwartz MW. 2002. Attenuation of diabetic hyperphagia in neuropeptide Y-deficient mice. Diabetes 51:778-783.
-
(2002)
Diabetes
, vol.51
, pp. 778-783
-
-
Sindelar, D.R.1
Mystkowski, P.2
Marsh, D.J.3
Palmiter, R.D.4
Schwartz, M.W.5
-
144
-
-
0344412855
-
Agouti expression in human adipose tissue: Functional consequences and increased expression in type 2 diabetes
-
Smith SR, Gawronska-Kozak B, Janderova L, Nguyen T, Murrell A, Stephens JM, Mynatt RL. 2003. Agouti expression in human adipose tissue: Functional consequences and increased expression in type 2 diabetes. Diabetes 52:2014-2022.
-
(2003)
Diabetes
, vol.52
, pp. 2014-2022
-
-
Smith, S.R.1
Gawronska-Kozak, B.2
Janderova, L.3
Nguyen, T.4
Murrell, A.5
Stephens, J.M.6
Mynatt, R.L.7
-
145
-
-
0036750241
-
Adiponectin -Its role in metabolism and beyond
-
Stefan N, Stumvoll M. 2002. Adiponectin -its role in metabolism and beyond. Horm Metab Res 34:469-473.
-
(2002)
Horm. Metab. Res.
, vol.34
, pp. 469-473
-
-
Stefan, N.1
Stumvoll, M.2
-
146
-
-
0141675985
-
Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects
-
Stenlof K, Wernstedt I, Fjallman T, Wallenius V, Wallenius K, Jansson JO. 2003. Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects. J Clin Endocrinol Metab 88:4379-4383.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 4379-4383
-
-
Stenlof, K.1
Wernstedt, I.2
Fjallman, T.3
Wallenius, V.4
Wallenius, K.5
Jansson, J.O.6
-
147
-
-
0036134187
-
Resistin and obesity-associated insulin resistance
-
Steppan CM, Kazar MA. 2002. Resistin and obesity-associated insulin resistance. Trends Endocrinol Metab 13:18-23.
-
(2002)
Trends Endocrinol. Metab.
, vol.13
, pp. 18-23
-
-
Steppan, C.M.1
Kazar, M.A.2
-
148
-
-
0035905758
-
The hormone resistin links to diabetes
-
Steppan CM, Balley ST, Bhat S, Brown EJ, Banerjec RR, Wright CM, Fatel HR, Ahima RS, Lazzar MA. 2001. The hormone resistin links to diabetes. Nature 409:307-312.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Balley, S.T.2
Bhat, S.3
Brown, E.J.4
Banerjec, R.R.5
Wright, C.M.6
Fatel, H.R.7
Ahima, R.S.8
Lazzar, M.A.9
-
149
-
-
0035882214
-
Central and peripheral dysregulation of melanin-concentrating hormone in obese Zucker rats
-
Stricker-Krongrad A, Dimitrov T, Beck B. 2001. Central and peripheral dysregulation of melanin-concentrating hormone in obese Zucker rats. Brain Res Mol Brain Res 92:43-48.
-
(2001)
Brain Res. Mol. Brain Res.
, vol.92
, pp. 43-48
-
-
Stricker-Krongrad, A.1
Dimitrov, T.2
Beck, B.3
-
150
-
-
0030063440
-
Current views on obesity
-
Stunkard AJ. 1996. Current views on obesity. Am J Med 100:230-236.
-
(1996)
Am. J. Med.
, vol.100
, pp. 230-236
-
-
Stunkard, A.J.1
-
151
-
-
0242580169
-
Deletion of ghrelin impairs neither growth nor appetite
-
Sun Y, Ahmed S, Smith RG. 2003. Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol 23:7973-7981.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 7973-7981
-
-
Sun, Y.1
Ahmed, S.2
Smith, R.G.3
-
152
-
-
1842480284
-
Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
-
Sun Y, Wang P, Zheng H, Smith RG. 2004. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Nat Acad Sci USA 101:4679-4684.
-
(2004)
Proc. Nat. Acad. Sci. USA
, vol.101
, pp. 4679-4684
-
-
Sun, Y.1
Wang, P.2
Zheng, H.3
Smith, R.G.4
-
154
-
-
1642463375
-
Translational medicine in fish-derived peptides: From fish endocrinology to human physiology and diseases
-
Takahsahi K. 2004. Translational medicine in fish-derived peptides: From fish endocrinology to human physiology and diseases. Endocr J 51:1-17.
-
(2004)
Endocr. J.
, vol.51
, pp. 1-17
-
-
Takahsahi, K.1
-
155
-
-
0033914183
-
The proglucagon-derived peptide, glucagons-like peptide 2, is a neurotransmitter involved in the regulation of food intake
-
Tang-Christensen M, Larsen PJ, Thulesen J, Rokier J, Vrang N. 2000. The proglucagon-derived peptide, glucagons-like peptide 2, is a neurotransmitter involved in the regulation of food intake. Nat Med 6:802-807.
-
(2000)
Nat. Med.
, vol.6
, pp. 802-807
-
-
Tang-Christensen, M.1
Larsen, P.J.2
Thulesen, J.3
Rokier, J.4
Vrang, N.5
-
156
-
-
10744223439
-
Neuroendocrine and metabolic effects of acute ghrelin administration in human obesity
-
Tassone F, Brogio F, Destefanis S, Rovere S, Benso A, Cottero C, Prodam F, Rossetto R, Gauna C, van der Lely AJ, Ghigo E, Maccario M. 2003. Neuroendocrine and metabolic effects of acute ghrelin administration in human obesity. J Clin Endocrinol Metab 88:5478-5483.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 5478-5483
-
-
Tassone, F.1
Brogio, F.2
Destefanis, S.3
Rovere, S.4
Benso, A.5
Cottero, C.6
Prodam, F.7
Rossetto, R.8
Gauna, C.9
van der Lely, A.J.10
Ghigo, E.11
Maccario, M.12
-
157
-
-
0020419772
-
Neuropeptide Y: Complete amino acid sequence of the brain peptide
-
Tatemoto K. 1982. Neuropeptide Y: Complete amino acid sequence of the brain peptide: Proc Nat Acad Sci USA 79:5483-5489.
-
(1982)
Proc. Nat. Acad. Sci. USA
, vol.79
, pp. 5483-5489
-
-
Tatemoto, K.1
-
158
-
-
1042275336
-
Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor
-
Thompson NM, Gill DA, Davies R, Loveridge N, Houston PA, Robinson IC, Wells T. 2004. Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor. Endocrinology 145:234-242.
-
(2004)
Endocrinology
, vol.145
, pp. 234-242
-
-
Thompson, N.M.1
Gill, D.A.2
Davies, R.3
Loveridge, N.4
Houston, P.A.5
Robinson, I.C.6
Wells, T.7
-
159
-
-
0030729210
-
Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
-
Thornton JE, Cheung CC, Clifton DK, Steiner RA. 1997. Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice. Endocrinology 138:5063-5066.
-
(1997)
Endocrinology
, vol.138
, pp. 5063-5066
-
-
Thornton, J.E.1
Cheung, C.C.2
Clifton, D.K.3
Steiner, R.A.4
-
160
-
-
0034880655
-
Determinations of the impaired secretion of glucagons-like peptide-1 in type 2 diabetes patients
-
Toft-Niesen M-B, Damholt MB, Madsbad S, Hilsted LM, Hughes TE, Michelsen BK, Holst JJ. 2001. Determinations of the impaired secretion of glucagons-like peptide-1 in type 2 diabetes patients. J Clin Endocrinol Metab 86:3717-3723.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 3717-3723
-
-
Toft-Niesen, M.-B.1
Damholt, M.B.2
Madsbad, S.3
Hilsted, L.M.4
Hughes, T.E.5
Michelsen, B.K.6
Holst, J.J.7
-
161
-
-
0035094970
-
Differential regulation of neuropeptide Y receptors in the brain of NPY knock-out mice
-
Trivedi PG, Yu H, Trumbauer M, Chen H, Van der Ploeg LH, Guan X. 2001. Differential regulation of neuropeptide Y receptors in the brain of NPY knock-out mice. Peptides 22:395-403.
-
(2001)
Peptides
, vol.22
, pp. 395-403
-
-
Trivedi, P.G.1
Yu, H.2
Trumbauer, M.3
Chen, H.4
Van der Ploeg, L.H.5
Guan, X.6
-
163
-
-
0030782520
-
Dose-dependent effects of recombinant human interleukin-6 on glucose regulation
-
Tsigos C, Papanicolaou DA, Kytou I, Defensor R, Mitstadis CS, Chrousos GF. 1997. Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. J Clin Endocrinol Metab 82:4167-4170.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 4167-4170
-
-
Tsigos, C.1
Papanicolaou, D.A.2
Kytou, I.3
Defensor, R.4
Mitstadis, C.S.5
Chrousos, G.F.6
-
164
-
-
0024434127
-
Acetylation alters the feeding response to MSH and beta-endorphin
-
Tsujii S, Bray GA. 1989. Acetylation alters the feeding response to MSH and beta-endorphin. Brain Res Bull 23:165-169.
-
(1989)
Brain Res. Bull.
, vol.23
, pp. 165-169
-
-
Tsujii, S.1
Bray, G.A.2
-
165
-
-
8744249918
-
The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin
-
Tucci SA, Rogers EK, Korbonits M, Kirkham TC. 2004. The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin. Br J Pharmacol 143:520-523.
-
(2004)
Br. J. Pharmacol.
, vol.143
, pp. 520-523
-
-
Tucci, S.A.1
Rogers, E.K.2
Korbonits, M.3
Kirkham, T.C.4
-
166
-
-
13344282056
-
A role for glucagons-like peptide-1 in the central regulation of feeding
-
Turton MD, O'Shea D, Gunn IN, Beak SA, Edwards CM, Meeran K, Chol SJ, Taylor GM, Heath MM, Lambert PD, Wilding JP, Smith DM, Ghatel MA, Herbert J, Bloom SR. 1996. A role for glucagons-like peptide-1 in the central regulation of feeding. Nature 379:69-72.
-
(1996)
Nature
, vol.379
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.N.3
Beak, S.A.4
Edwards, C.M.5
Meeran, K.6
Chol, S.J.7
Taylor, G.M.8
Heath, M.M.9
Lambert, P.D.10
Wilding, J.P.11
Smith, D.M.12
Ghatel, M.A.13
Herbert, J.14
Bloom, S.R.15
-
167
-
-
0031802864
-
Hypothalamic corticotropin-releasing hormone is a mediator of the anorexigenic effect of leptin
-
Uehara Y, Shimizu H, Ohtani K, Sato N, Mori M. 1998. Hypothalamic corticotropin-releasing hormone is a mediator of the anorexigenic effect of leptin. Diabetes 47:890-893.
-
(1998)
Diabetes
, vol.47
, pp. 890-893
-
-
Uehara, Y.1
Shimizu, H.2
Ohtani, K.3
Sato, N.4
Mori, M.5
-
168
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamislgii GS. 1997. Protection from obesity-induced insulin resistance in mice lacking TNF-α function. Nature 389:610-614.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamislgii, G.S.4
-
169
-
-
0030864185
-
Targeted disruption of the tumor necrosis factor-alpha gene: Metabolic consequences in obese and nonobese mice
-
Ventre J, Doebber T, Wu M, MacNaul K, Stevens K, Pasparakie M, Kollias G, Moller DE. 1997. Targeted disruption of the tumor necrosis factor-alpha gene: Metabolic consequences in obese and nonobese mice. Diabetes 48:1526-1531.
-
(1997)
Diabetes
, vol.48
, pp. 1526-1531
-
-
Ventre, J.1
Doebber, T.2
Wu, M.3
MacNaul, K.4
Stevens, K.5
Pasparakie, M.6
Kollias, G.7
Moller, D.E.8
-
170
-
-
0035041922
-
Obesity as a neuroendocrine disease: Lessons to be learned from proopiomelanocortin and melanocortin receptor mutations in mice and men
-
Wardlaw SL. 2001. Obesity as a neuroendocrine disease: Lessons to be learned from proopiomelanocortin and melanocortin receptor mutations in mice and men. J Clin Endocrinol Metab 86:1442-1446.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1442-1446
-
-
Wardlaw, S.L.1
-
171
-
-
0036152683
-
Interleukin-6-deficient mice develop mature-onset obesity
-
Wallenius V, Wallenius K, Ahren B, Rudling M, Gartstan H, Dickson SL, Ohlsson C, Jansson JO. 2002a. Interleukin-6-deficient mice develop mature-onset obesity. Nat Med 8:75-79.
-
(2002)
Nat. Med.
, vol.8
, pp. 75-79
-
-
Wallenius, V.1
Wallenius, K.2
Ahren, B.3
Rudling, M.4
Gartstan, H.5
Dickson, S.L.6
Ohlsson, C.7
Jansson, J.O.8
-
172
-
-
0036295573
-
Intracerebroventricular interleukin-6 treatment decreases body fat in rats
-
Wallenius K, Wallenius V, Sunter D, Dickson SL, Jansson JD. 2002b. Intracerebroventricular interleukin-6 treatment decreases body fat in rats. Biochem Biophys Res Commun 293:560-565.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 560-565
-
-
Wallenius, K.1
Wallenius, V.2
Sunter, D.3
Dickson, S.L.4
Jansson, J.D.5
-
173
-
-
0031465745
-
Regulation of glucose transporters and hexose uptake in 3T3-L1 adipocytes: Glucagons-like peptide-1 and insulin interactions
-
Wang Y, Kole HK, Montrose-Rafizaden C, Perfetti R, Bernier M, Egan JM. 1997. Regulation of glucose transporters and hexose uptake in 3T3-L1 adipocytes: Glucagons-like peptide-1 and insulin interactions. J Mol Endocrinol 19:241-248.
-
(1997)
J. Mol. Endocrinol.
, vol.19
, pp. 241-248
-
-
Wang, Y.1
Kole, H.K.2
Montrose-Rafizaden, C.3
Perfetti, R.4
Bernier, M.5
Egan, J.M.6
-
174
-
-
10344236432
-
Regulated membrane trafficking of the insulin-responsive glucose transport 4 in adipocytes
-
Watson RT, Naknzaki M, Pessin JE. 2004. Regulated membrane trafficking of the insulin-responsive glucose transport 4 in adipocytes. Endocr Rev 25:177-204.
-
(2004)
Endocr. Rev.
, vol.25
, pp. 177-204
-
-
Watson, R.T.1
Naknzaki, M.2
Pessin, J.E.3
-
175
-
-
0242641149
-
Adipose tissue resistin expression in severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor-γ agonist
-
Way JM, Gorgun CZ, Tong G, Uysal KT, Brown KK, Harrington WW, Oliver Jr., WR, Willson TM, Kliewet SA, Hotamistigli GS. 2001. Adipose tissue resistin expression in severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor-γ agonist. J Biol Chem 276:25651-25653.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25651-25653
-
-
Way, J.M.1
Gorgun, C.Z.2
Tong, G.3
Uysal, K.T.4
Brown, K.K.5
Harrington, W.W.6
Oliver Jr., W.R.7
Willson, T.M.8
Kliewet, S.A.9
Hotamistigli, G.S.10
-
176
-
-
0034999667
-
Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
-
Weyer C, Funahashi T, Tanaka S, Hotta S, Hotta K, Matsuzawa Y, Pratley RE, Tataranni PA. 2001. Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86:1930-1935.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1930-1935
-
-
Weyer, C.1
Funahashi, T.2
Tanaka, S.3
Hotta, S.4
Hotta, K.5
Matsuzawa, Y.6
Pratley, R.E.7
Tataranni, P.A.8
-
177
-
-
0032577376
-
Signals that regulate food intake and energy homeostasis
-
Woods SC, Seeley RJ, Porte Jr, D, Schwartz MW. 1998. Signals that regulate food intake and energy homeostasis. Science 280:1378-1383.
-
(1998)
Science
, vol.280
, pp. 1378-1383
-
-
Woods, S.C.1
Seeley, R.J.2
Porte Jr., D.3
Schwartz, M.W.4
-
178
-
-
2542428992
-
Deletion of ghrelin reveals on effect on food intake, but a primary role in energy balance
-
Wortley KE, Anderson K, Garcia K, Murray J, Malinova L, Liu R, Moncrieffe M, Thabet K, Cox H, Yancopoulos GD, Wiegand SJ, Sleeman MW. 2004. Deletion of ghrelin reveals on effect on food intake, but a primary role in energy balance. Obes Res 12:170.
-
(2004)
Obes. Res.
, vol.12
, pp. 170
-
-
Wortley, K.E.1
Anderson, K.2
Garcia, K.3
Murray, J.4
Malinova, L.5
Liu, R.6
Moncrieffe, M.7
Thabet, K.8
Cox, H.9
Yancopoulos, G.D.10
Wiegand, S.J.11
Sleeman, M.W.12
-
179
-
-
0035216623
-
Ghrelin enhances appetite and increases food intake in humans
-
Wren AM, Seal LJ, Cohan MA, Brynes AE, Frost GS, Murphy KG, Dhille WS, Ghatel MA, Blood SR. 2001. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 86:5992-5995.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 5992-5995
-
-
Wren, A.M.1
Seal, L.J.2
Cohan, M.A.3
Brynes, A.E.4
Frost, G.S.5
Murphy, K.G.6
Dhille, W.S.7
Ghatel, M.A.8
Blood, S.R.9
-
180
-
-
0033543754
-
Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor1
-
Xu H, Sethi JK, Hotamisligil GS. 1999. Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor1. J Biol Chem 274:26287-26295.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26287-26295
-
-
Xu, H.1
Sethi, J.K.2
Hotamisligil, G.S.3
-
181
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi T, Kamon I, Waki H, Terauchi Y, Kubota N, Hata Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavlirova O, Vinson CR, Kimura S, Tomita M, Froguel P, Kadowaki T. 2001. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7:941-946.
-
(2001)
Nat. Med.
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, I.2
Waki, H.3
Terauchi, Y.4
Kubota, N.5
Hata, Y.6
Ide, T.7
Murakami, K.8
Tsuboyama-Kasaoka, N.9
Ezaki, O.10
Akanuma, Y.11
Gavlirova, O.12
Vinson, C.R.13
Kimura, S.14
Tomita, M.15
Froguel, P.16
Kadowaki, T.17
-
182
-
-
0037494960
-
Cloning of adiponectin receptors that mediate antidiabetic effects
-
Yamauchi T, Kammon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hata K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T. 2003a. Cloning of adiponectin receptors that mediate antidiabetic effects. Nature 423:762-769.
-
(2003)
Nature
, vol.423
, pp. 762-769
-
-
Yamauchi, T.1
Kammon, J.2
Ito, Y.3
Tsuchida, A.4
Yokomizo, T.5
Kita, S.6
Sugiyama, T.7
Miyagishi, M.8
Hata, K.9
Tsunoda, M.10
Murakami, K.11
Ohteki, T.12
Uchida, S.13
Takekawa, S.14
Waki, H.15
Tsuno, N.H.16
Shibata, Y.17
Terauchi, Y.18
Froguel, P.19
Tobe, K.20
Koyasu, S.21
Taira, K.22
Kitamura, T.23
Shimizu, T.24
Nagai, R.25
Kadowaki, T.26
more..
-
183
-
-
0037462684
-
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis
-
Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Takakuwa K, Matsui J, Taketa M, Eto K, Terauchi Y, Komeda K, Tsunoda M, Murakami K, Ohnishi Y, Naitoh T, Yamamura K, Ueyama Y, Froguel P, Kimura S, Nagai R, Kadowaki T. 2003. Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis. J Biol Chem 278: 2461-2468.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2461-2468
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Imai, Y.4
Shimozawa, N.5
Hioki, K.6
Uchida, S.7
Ito, Y.8
Takakuwa, K.9
Matsui, J.10
Taketa, M.11
Eto, K.12
Terauchi, Y.13
Komeda, K.14
Tsunoda, M.15
Murakami, K.16
Ohnishi, Y.17
Naitoh, T.18
Yamamura, K.19
Ueyama, Y.20
Froguel, P.21
Kimura, S.22
Nagai, R.23
Kadowaki, T.24
more..
-
184
-
-
0033279159
-
Differential expression of a novel seven transmembrane domain protein in epididymal fat from aged and diabetic mice
-
Yang H, Egan JM, Rodgers BD, Bernier M, Montrose-Rafizadeh C. 1999. Differential expression of a novel seven transmembrane domain protein in epididymal fat from aged and diabetic mice. Endocrinology 140:2859-2867.
-
(1999)
Endocrinology
, vol.140
, pp. 2859-2867
-
-
Yang, H.1
Egan, J.M.2
Rodgers, B.D.3
Bernier, M.4
Montrose-Rafizadeh, C.5
-
185
-
-
0037462926
-
The gene expression profiling of human visceral adipose tissue and its secretary functions
-
Yang YS, Song HD, Li RY, Zhou LB, Zhu ZD, Hu RM, Han ZG, Chen JL. 2003. The gene expression profiling of human visceral adipose tissue and its secretary functions. Biochem Biophys Res Commun 300:839-846.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.300
, pp. 839-846
-
-
Yang, Y.S.1
Song, H.D.2
Li, R.Y.3
Zhou, L.B.4
Zhu, Z.D.5
Hu, R.M.6
Han, Z.G.7
Chen, J.L.8
-
186
-
-
0032863468
-
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
-
Yaswen L, Diehl N, Brennan MB, Hochgreschwender U. 1999. Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Nat Genet 9:1068-1070.
-
(1999)
Nat. Genet.
, vol.9
, pp. 1068-1070
-
-
Yaswen, L.1
Diehl, N.2
Brennan, M.B.3
Hochgreschwender, U.4
-
188
-
-
0036105778
-
Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins
-
Yokota T, Meka CS, Medina KL, Igarashi H, Comp PC, Takahashi M, Nishida M, Oritani K, Miyagawa J, Funahashi T, Tomiyama Y, Matsuzawa Y, Kincarde PW. 2002. Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins. J Clin Invest 109:1303-1310.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1303-1310
-
-
Yokota, T.1
Meka, C.S.2
Medina, K.L.3
Igarashi, H.4
Comp, P.C.5
Takahashi, M.6
Nishida, M.7
Oritani, K.8
Miyagawa, J.9
Funahashi, T.10
Tomiyama, Y.11
Matsuzawa, Y.12
Kincarde, P.W.13
-
189
-
-
0037045845
-
Effect of 6-week course of glucagons-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: A parallel study
-
Zander M, Madsbad S, Madsen JL, Holst JJ. 2002. Effect of 6-week course of glucagons-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: A parallel study. Lancet 359:824-830.
-
(2002)
Lancet
, vol.359
, pp. 824-830
-
-
Zander, M.1
Madsbad, S.2
Madsen, J.L.3
Holst, J.J.4
-
190
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman J. 1994. Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.6
-
191
-
-
2342582164
-
Inhibition of adipogenesis by ghrelin
-
Zhang W, Zhao L, Li TR, Chai B, Fan Y, Gantz I, Mulholland MW. 2004. Inhibition of adipogenesis by ghrelin. Mol Biol Cell 15:2484-2491.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2484-2491
-
-
Zhang, W.1
Zhao, L.2
Li, T.R.3
Chai, B.4
Fan, Y.5
Gantz, I.6
Mulholland, M.W.7
|