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Volumn 88, Issue 11, 2003, Pages 5478-5483

Neuroendocrine and Metabolic Effects of Acute Ghrelin Administration in Human Obesity

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; GHRELIN; GLUCOSE; GROWTH HORMONE; INSULIN; PROLACTIN;

EID: 10744223439     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-030564     Document Type: Article
Times cited : (107)

References (66)
  • 1
    • 0035688260 scopus 로고    scopus 로고
    • Purification and distribution of ghrelin: The natural endogenous ligand for the growth hormone secretagogue receptor
    • Kojima M, Hosoda H, Kangawa K 2001 Purification and distribution of ghrelin: the natural endogenous ligand for the growth hormone secretagogue receptor. Horm Res 56(Suppl 1):93-97
    • (2001) Horm Res , vol.56 , Issue.1 SUPPL. , pp. 93-97
    • Kojima, M.1    Hosoda, H.2    Kangawa, K.3
  • 2
    • 0037066587 scopus 로고    scopus 로고
    • Neuroendocrine and peripheral activities of ghrelin: Implications in metabolism and obesity
    • Muccioli G, Tschöp M, Papotti M, Deghenghi R, Heiman M, Ghigo E 2002 Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity. Eur J Pharmacol 440:235-254
    • (2002) Eur J Pharmacol , vol.440 , pp. 235-254
    • Muccioli, G.1    Tschöp, M.2    Papotti, M.3    Deghenghi, R.4    Heiman, M.5    Ghigo, E.6
  • 5
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K 1999 Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:656-660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 11
    • 0037355648 scopus 로고    scopus 로고
    • Ghrelin and insulin metabolism
    • Ukkola O 2003 Ghrelin and insulin metabolism. Eur J Clin Endocrinol 33: 183-185
    • (2003) Eur J Clin Endocrinol , vol.33 , pp. 183-185
    • Ukkola, O.1
  • 17
    • 0038030760 scopus 로고    scopus 로고
    • Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels
    • Barkan AL, Dimaraki EV, Jessup SK, Symons KV, Ermolenko M, Jaffe CA 2003 Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels. J Clin Endocrinol Metab 88:2180-2184
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2180-2184
    • Barkan, A.L.1    Dimaraki, E.V.2    Jessup, S.K.3    Symons, K.V.4    Ermolenko, M.5    Jaffe, C.A.6
  • 22
    • 0036260311 scopus 로고    scopus 로고
    • Ghrelin, growth and obesity
    • Ukkola O, Poykko S 2002 Ghrelin, growth and obesity. Ann Med 34:102-108
    • (2002) Ann Med , vol.34 , pp. 102-108
    • Ukkola, O.1    Poykko, S.2
  • 23
    • 0000067107 scopus 로고    scopus 로고
    • Genetics and pathophysiology of human obesity
    • Cummings DE, Schwartz MW 2003 Genetics and pathophysiology of human obesity. Annu Rev Med 4:453-471
    • (2003) Annu Rev Med , vol.4 , pp. 453-471
    • Cummings, D.E.1    Schwartz, M.W.2
  • 24
    • 4243634378 scopus 로고    scopus 로고
    • Euglycemic hyperinsulinemia, but not lipid infusion, decreases circulating ghrelin levels in humans
    • Mohlig M, Spranger J, Otto B, Ristow M, Tschop M, Pfeiffer AF 2002 Euglycemic hyperinsulinemia, but not lipid infusion, decreases circulating ghrelin levels in humans. J Endocrinol Invest 25:RC36-RC38
    • (2002) J Endocrinol Invest , vol.25
    • Mohlig, M.1    Spranger, J.2    Otto, B.3    Ristow, M.4    Tschop, M.5    Pfeiffer, A.F.6
  • 27
    • 0037372044 scopus 로고    scopus 로고
    • Dose-dependent inhibition by ghrelin of insulin secretion in the mouse
    • Reimer MK, Pacini G, Ahren B 2003 Dose-dependent inhibition by ghrelin of insulin secretion in the mouse. Endocrinology 144:916-921
    • (2003) Endocrinology , vol.144 , pp. 916-921
    • Reimer, M.K.1    Pacini, G.2    Ahren, B.3
  • 28
    • 0037220691 scopus 로고    scopus 로고
    • Plasma ghrelin concentrations are not regulated by glucose or insulin: A double-bind, placebo-controlled crossover clamp study
    • Schaller G, Scmidt A, Pleiner J, Woloszczuk W, Wolzt M, Luger A 2003 Plasma ghrelin concentrations are not regulated by glucose or insulin: a double-bind, placebo-controlled crossover clamp study. Diabetes 52:16-20
    • (2003) Diabetes , vol.52 , pp. 16-20
    • Schaller, G.1    Scmidt, A.2    Pleiner, J.3    Woloszczuk, W.4    Wolzt, M.5    Luger, A.6
  • 31
    • 0036854343 scopus 로고    scopus 로고
    • Circulating ghrelin concentrations are lowered by intravenous glucose or hyperinsulinemic euglycemic conditions in rodents
    • McCowen KC, Maykel JA, Bistran BR, Ling PR 2002 Circulating ghrelin concentrations are lowered by intravenous glucose or hyperinsulinemic euglycemic conditions in rodents. J Endocrinol 175:R7-R11
    • (2002) J Endocrinol , vol.175
    • McCowen, K.C.1    Maykel, J.A.2    Bistran, B.R.3    Ling, P.R.4
  • 32
    • 0036714764 scopus 로고    scopus 로고
    • Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: Responses to the intravenous and oral administration of glucose
    • Nakagawa E, Nagaya N, Okumura H, Enomoto M, Oya H, Ono F, Hosoda H, Kojima M, Kangawa K 2002 Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: responses to the intravenous and oral administration of glucose. Clin Sci 103:325-328
    • (2002) Clin Sci , vol.103 , pp. 325-328
    • Nakagawa, E.1    Nagaya, N.2    Okumura, H.3    Enomoto, M.4    Oya, H.5    Ono, F.6    Hosoda, H.7    Kojima, M.8    Kangawa, K.9
  • 34
    • 0343627970 scopus 로고    scopus 로고
    • Neuroendocrine abnormalities in visceral obesity
    • Bjontorp P, Rosmond R 2000 Neuroendocrine abnormalities in visceral obesity. Int J Obes Relat Metab Disord 24(Suppl 2):S800-S885
    • (2000) Int J Obes Relat Metab Disord , vol.24 , Issue.2 SUPPL.
    • Bjontorp, P.1    Rosmond, R.2
  • 36
    • 0036107852 scopus 로고    scopus 로고
    • Neuroendocrine and metabolic determinants of the adaptation of GH/IGF-I axis to obesity
    • Maccario M, Tassone F, Grottoli S, Rossetto R, Gauna C, Ghigo E 2002 Neuroendocrine and metabolic determinants of the adaptation of GH/IGF-I axis to obesity. Ann Endocrinol 63:140-144
    • (2002) Ann Endocrinol , vol.63 , pp. 140-144
    • Maccario, M.1    Tassone, F.2    Grottoli, S.3    Rossetto, R.4    Gauna, C.5    Ghigo, E.6
  • 41
    • 0035085142 scopus 로고    scopus 로고
    • Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin
    • Tannenbaum GS, Bowers CY 2001 Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin. Endocrine 14: 21-27
    • (2001) Endocrine , vol.14 , pp. 21-27
    • Tannenbaum, G.S.1    Bowers, C.Y.2
  • 42
    • 0037372024 scopus 로고    scopus 로고
    • Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone secretion
    • Tannenbaum GS, Epelbaum J, Bowers CY 2003 Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone secretion. Endocrinology 144:967-974
    • (2003) Endocrinology , vol.144 , pp. 967-974
    • Tannenbaum, G.S.1    Epelbaum, J.2    Bowers, C.Y.3
  • 45
    • 0036679260 scopus 로고    scopus 로고
    • Central ghrelin production does not substantially contribute to systemic ghrelin concentrations: A study in two subjects with active acromegaly
    • van der Toorn FM, Janssen JA, de Herder WW, Broglio F, Ghigo E, van der Lely AJ 2002 Central ghrelin production does not substantially contribute to systemic ghrelin concentrations: a study in two subjects with active acromegaly. Eur J Endocrinol 147:195-199
    • (2002) Eur J Endocrinol , vol.147 , pp. 195-199
    • Van Der Toorn, F.M.1    Janssen, J.A.2    De Herder, W.W.3    Broglio, F.4    Ghigo, E.5    Van Der Lely, A.J.6
  • 47
    • 0036736468 scopus 로고    scopus 로고
    • Immunoreactive ghrelin in human cord blood: Relation to anthropometry, leptin, and growth hormone
    • Chanoine JP, Yeung LP, Wong AC, Birmingham CL 2002 Immunoreactive ghrelin in human cord blood: relation to anthropometry, leptin, and growth hormone. J Pediatr Gastroenterol Nutr 35:282-286
    • (2002) J Pediatr Gastroenterol Nutr , vol.35 , pp. 282-286
    • Chanoine, J.P.1    Yeung, L.P.2    Wong, A.C.3    Birmingham, C.L.4
  • 53
    • 0029784296 scopus 로고    scopus 로고
    • Sex-related alterations in hypothalamic growth hormone-releasing hormone mRNA-but not somatostatin mRNA-expressing cells in genetically obese Zucker rats
    • Tannenbaum GS, Epelbaum J, Videau C, Dubuis JM 1996 Sex-related alterations in hypothalamic growth hormone-releasing hormone mRNA-but not somatostatin mRNA-expressing cells in genetically obese Zucker rats. Neuroendocrinology 64:186-193
    • (1996) Neuroendocrinology , vol.64 , pp. 186-193
    • Tannenbaum, G.S.1    Epelbaum, J.2    Videau, C.3    Dubuis, J.M.4
  • 54
    • 0032905676 scopus 로고    scopus 로고
    • Effects of recombinant human insulin-like growth factor I administration on growth hormone (GH) secretion, both spontaneous and stimulated by GH-releasing hormone or hexarelin, a peptidyl GH secretagogue, in humans
    • Ghigo E, Gianotti L, Arvat E, Ramunni J, Valetto MR, Broglio F, Rolla M, Cavagnini F, Muller EE 1999 Effects of recombinant human insulin-like growth factor I administration on growth hormone (GH) secretion, both spontaneous and stimulated by GH-releasing hormone or hexarelin, a peptidyl GH secretagogue, in humans. J Clin Endocrinol Metab 84:285-290
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 285-290
    • Ghigo, E.1    Gianotti, L.2    Arvat, E.3    Ramunni, J.4    Valetto, M.R.5    Broglio, F.6    Rolla, M.7    Cavagnini, F.8    Muller, E.E.9
  • 56
    • 0345151982 scopus 로고    scopus 로고
    • Anterior pituitary
    • Larsen PR, Reed P, Kronenberg HM, Melmed S, Polonsky KS, eds. Philadelphia: Elsevier Science
    • Melmed S, Kleinberg DL 2003 Anterior pituitary. In: Larsen PR, Reed P, Kronenberg HM, Melmed S, Polonsky KS, eds. Williams textbook of endocrinology. 10th ed. Philadelphia: Elsevier Science; 177-280
    • (2003) Williams Textbook of Endocrinology. 10th Ed. , pp. 177-280
    • Melmed, S.1    Kleinberg, D.L.2
  • 57
    • 0033928131 scopus 로고    scopus 로고
    • Physiopathology of prolactin secretion in obesity
    • Kopelman PG 2000 Physiopathology of prolactin secretion in obesity. Int J Obes Relat Metab Disord 24(Suppl 2):S104-S108
    • (2000) Int J Obes Relat Metab Disord , vol.24 , Issue.2 SUPPL.
    • Kopelman, P.G.1
  • 61
    • 0036083399 scopus 로고    scopus 로고
    • Ghrelin stimulates insulin secretion from the pancreas of normal and diabetic rats
    • Adeghate E, Ponery AS 2002 Ghrelin stimulates insulin secretion from the pancreas of normal and diabetic rats. J Neuroendocrinol 14:555-560
    • (2002) J Neuroendocrinol , vol.14 , pp. 555-560
    • Adeghate, E.1    Ponery, A.S.2
  • 64
    • 0037098974 scopus 로고    scopus 로고
    • The ghrelin cell: A novel developmentally regulated islet cell in the human pancreas
    • Wierup N, Svensson H, Sundler F 2002 The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas. Regul Pept 107:63-69
    • (2002) Regul Pept , vol.107 , pp. 63-69
    • Wierup, N.1    Svensson, H.2    Sundler, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.