-
1
-
-
0031838353
-
Severe early onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
-
Krude, H. et al. Severe early onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nature Genet. 19, 155-157 (1998).
-
(1998)
Nature Genet.
, vol.19
, pp. 155-157
-
-
Krude, H.1
-
2
-
-
0031455342
-
Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the quebec family study
-
Chagnon, Y.C. et al. Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the quebec family study. Mol. Med. 3, 663-673 (1997).
-
(1997)
Mol. Med.
, vol.3
, pp. 663-673
-
-
Chagnon, Y.C.1
-
3
-
-
0031668219
-
A frameshift mutation in MC4R associated with dominantly inherited human obesity
-
Yeo, G.S.H. et al. A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nature Genet. 20, 111-112 (1998).
-
(1998)
Nature Genet.
, vol.20
, pp. 111-112
-
-
Yeo, G.S.H.1
-
4
-
-
0031662163
-
A frameshift mutation in human MC4R is associated with a dominant form of obesity
-
Vaisse, C., Clement, K., Guy-Grand, B. & Froguel, P. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nature Genet. 20, 113-114 (1998).
-
(1998)
Nature Genet.
, vol.20
, pp. 113-114
-
-
Vaisse, C.1
Clement, K.2
Guy-Grand, B.3
Froguel, P.4
-
6
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann, M.M. et al. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278, 135-138 (1997).
-
(1997)
Science
, vol.278
, pp. 135-138
-
-
Ollmann, M.M.1
-
7
-
-
0031280002
-
Overexpression of Agrt leads to obesity in transgenic mice
-
Graham, M., Shutter, J.R., Sarmiento, U., Sarosi, I. & Stark, K.L. Overexpression of Agrt leads to obesity in transgenic mice. Nature Genet. 17, 273-274 (1997).
-
(1997)
Nature Genet.
, vol.17
, pp. 273-274
-
-
Graham, M.1
Shutter, J.R.2
Sarmiento, U.3
Sarosi, I.4
Stark, K.L.5
-
8
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar, D. et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88, 131-141 (1997).
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
-
9
-
-
0030614331
-
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
-
Fan, W., Boston, B.A., Kesterson, R.A., Hruby, V.J. & Cone, R.D. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385, 165-168 (1997).
-
(1997)
Nature
, vol.385
, pp. 165-168
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
10
-
-
0028112970
-
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
-
Lu, D. et al. Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor. Nature 371, 799-802 (1994).
-
(1994)
Nature
, vol.371
, pp. 799-802
-
-
Lu, D.1
-
11
-
-
0032900284
-
Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides
-
Marsh, D.J. et al. Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. Nature Genet. 21, 119-122 (1999).
-
(1999)
Nature Genet.
, vol.21
, pp. 119-122
-
-
Marsh, D.J.1
-
12
-
-
0000304384
-
Role of the melanocortin-4 receptor in metabolic rate and food intake in mice
-
in press
-
Chen, A.S. et al. Role of the melanocortin-4 receptor in metabolic rate and food intake in mice. Transgenic Res. (in press).
-
Transgenic Res.
-
-
Chen, A.S.1
-
13
-
-
0027436690
-
Identification of a receptor for γ melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
-
Roselli-Rehfuss, L. et al. Identification of a receptor for γ melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc. Natl Acad. Sci. USA 90, 8856-8860 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8856-8860
-
-
Roselli-Rehfuss, L.1
-
14
-
-
0015473277
-
Cellularity of adipose depots in six strains of genetically obese mice
-
Johnson, P.R. & Hirsch, J. Cellularity of adipose depots in six strains of genetically obese mice. J. Lipid Res. 13, 2-11 (1972).
-
(1972)
J. Lipid Res.
, vol.13
, pp. 2-11
-
-
Johnson, P.R.1
Hirsch, J.2
-
16
-
-
0014814862
-
Lipolysis in genetically obese and diabetes-prone mice
-
Yen, T.T., Steinmetz, J. & Wolff, G.L. Lipolysis in genetically obese and diabetes-prone mice. Horm. Metab. Res. 2, 200-203 (1970).
-
(1970)
Horm. Metab. Res.
, vol.2
, pp. 200-203
-
-
Yen, T.T.1
Steinmetz, J.2
Wolff, G.L.3
-
17
-
-
0030062529
-
Upregulation of adipocyte metabolism by agouti protein: Possible paracrine actions in yellow mouse obesity
-
Jones, B.H. et al. Upregulation of adipocyte metabolism by agouti protein: possible paracrine actions in yellow mouse obesity. Am. J. Physiol. 270, E192-E196 (1996).
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Jones, B.H.1
-
19
-
-
0342858793
-
α-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression
-
Fekete, C. et al. α-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression. J. Neurosci. 20, 1550-1558 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 1550-1558
-
-
Fekete, C.1
-
20
-
-
0034037278
-
The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin
-
Kim, M.S. et al. The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin. J. Clin. Invest. 105, 1005-1011 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1005-1011
-
-
Kim, M.S.1
-
21
-
-
0023724613
-
1 hybrid mice to the same diets: Glucose tolerance, weight gain, and adipocyte cellularity
-
1 hybrid mice to the same diets: glucose tolerance, weight gain, and adipocyte cellularity. Int. J. Obes. 12, 305-320 (1988).
-
(1988)
Int. J. Obes.
, vol.12
, pp. 305-320
-
-
Frigeri, L.G.1
Wolff, G.L.2
Teguh, C.3
-
22
-
-
0024341408
-
Effects of MSH on food intake, body weight and coat color of the yellow obese mouse
-
Shimizu, H., Shargill, N.S., Bray, G.A., Yen, T.T. & Geselichen, P.D. Effects of MSH on food intake, body weight and coat color of the yellow obese mouse. Life Sci. 45, 543-552 (1989).
-
(1989)
Life Sci.
, vol.45
, pp. 543-552
-
-
Shimizu, H.1
Shargill, N.S.2
Bray, G.A.3
Yen, T.T.4
Geselichen, P.D.5
-
23
-
-
0029154516
-
Cyclic lactam α-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7, Lys10] α-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors
-
Hruby, V.J. et al. Cyclic lactam α-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7, Lys10] α-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors. J. Med. Chem. 38, 3454-3461 (1995).
-
(1995)
J. Med. Chem.
, vol.38
, pp. 3454-3461
-
-
Hruby, V.J.1
-
24
-
-
0033567543
-
Anatomy of an endogenous antagonist: Relationship between agouti-related protein and proopiomelanocortin in brain
-
Bagnol, D. et al. Anatomy of an endogenous antagonist: relationship between agouti-related protein and proopiomelanocortin in brain. J. Neurosci. 19, RC26 (1-7) (1999).
-
(1999)
J. Neurosci.
, vol.19
, Issue.1-7
-
-
Bagnol, D.1
-
25
-
-
0027456619
-
Molecular cloning of a novel melanocortin receptor
-
Gantz, I. et al. Molecular cloning of a novel melanocortin receptor. J. Biol. Chem. 268, 8246-8250 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8246-8250
-
-
Gantz, I.1
-
26
-
-
0029848043
-
Distribution of cDNA for melanocortin receptor subtypes in human tissues
-
Chhajlani, V. Distribution of cDNA for melanocortin receptor subtypes in human tissues, Biochem. Mol. Biol. Int. 38, 73-80 (1996).
-
(1996)
Biochem. Mol. Biol. Int.
, vol.38
, pp. 73-80
-
-
Chhajlani, V.1
-
27
-
-
1842292786
-
Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q
-
Lembertas, A.V. et al. Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q. J. Clin. Invest 100, 1240-1247 (1997).
-
(1997)
J. Clin. Invest
, vol.100
, pp. 1240-1247
-
-
Lembertas, A.V.1
-
28
-
-
0032584978
-
Evidence of altered hypothalamic proopiomelanocortin/neuropeptide Y mRNA expression in tubby mice
-
Guan, X.-M., Yu, H. & Van der Ploeg, L.H.T. Evidence of altered hypothalamic proopiomelanocortin/neuropeptide Y mRNA expression in tubby mice. Mol. Brain Res. 59, 273-279 (1998).
-
(1998)
Mol. Brain Res.
, vol.59
, pp. 273-279
-
-
Guan, X.-M.1
Yu, H.2
Van Der Ploeg, L.H.T.3
-
29
-
-
0032080082
-
DXA body composition: Theory and practice
-
Kelly, T.L., Berger, N. & Richardson, T.L. DXA body composition: theory and practice. Appl. Radiat. Isot. 49, 511-513 (1998).
-
(1998)
Appl. Radiat. Isot.
, vol.49
, pp. 511-513
-
-
Kelly, T.L.1
Berger, N.2
Richardson, T.L.3
-
30
-
-
0034116222
-
Human body composition: In vivo methods
-
Ellis, K.J. Human body composition: in vivo methods. Physiol. Rev. 80, 649-680 (2000).
-
(2000)
Physiol. Rev.
, vol.80
, pp. 649-680
-
-
Ellis, K.J.1
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