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Volumn 23, Issue 1, 2005, Pages 205-229

Tumoral drug metabolism: Overview and its implications for cancer therapy

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; BETA GLUCURONIDASE; CAPECITABINE; CHLORAMBUCIL; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOCHROME P450; DNA TOPOISOMERASE INHIBITOR; DOCETAXEL; DOXORUBICIN; DRUG METABOLIZING ENZYME; FLUTAMIDE; GLUCORONIDE TRANSFERASE; GLUTATHIONE TRANSFERASE; IFOSFAMIDE; IMATINIB; MELPHALAN; MITOMYCIN C; OXIDOREDUCTASE; PACLITAXEL; PRODRUG; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); RETINOIC ACID; SULFATASE; SULFOTRANSFERASE; TAMOXIFEN; TOREMIFENE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

EID: 16644379769     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.02.120     Document Type: Article
Times cited : (147)

References (258)
  • 1
    • 0035215722 scopus 로고    scopus 로고
    • Selected novel anticancer treatments targeting cell signalling proteins
    • Elsayad YA, Sausville EA: Selected novel anticancer treatments targeting cell signalling proteins. Oncologist 6:517-537, 2001
    • (2001) Oncologist , vol.6 , pp. 517-537
    • Elsayad, Y.A.1    Sausville, E.A.2
  • 2
    • 0030834058 scopus 로고    scopus 로고
    • Human cytochrome P450 enzymes: Status report summarizing their reactions, substrates, inducers and inhibitors
    • Rendic S: Human cytochrome P450 enzymes: Status report summarizing their reactions, substrates, inducers and inhibitors. Drug Metab Rev 29:413-580, 1997
    • (1997) Drug Metab Rev , vol.29 , pp. 413-580
    • Rendic, S.1
  • 4
    • 0035115599 scopus 로고    scopus 로고
    • Genetic multiplicity of the human UDP-Glucuronosyl-transferases and regulation in the gastrointestinal tract
    • Tukey RH, Strassburg CP: Genetic multiplicity of the human UDP-Glucuronosyl-transferases and regulation in the gastrointestinal tract. Mol Pharm 59:405-414, 2001
    • (2001) Mol Pharm , vol.59 , pp. 405-414
    • Tukey, R.H.1    Strassburg, C.P.2
  • 5
    • 0041381056 scopus 로고    scopus 로고
    • UGT pharmacogenomics: Implications for cancer risk and cancer therapeutics
    • Desai AA, Innocenti F, Ratain MJ: UGT pharmacogenomics: Implications for cancer risk and cancer therapeutics. Pharmacogenomics 13:517-523, 2003
    • (2003) Pharmacogenomics , vol.13 , pp. 517-523
    • Desai, A.A.1    Innocenti, F.2    Ratain, M.J.3
  • 6
    • 0642374221 scopus 로고    scopus 로고
    • The role of glutathione-S-transferase in anti-cancer drug resistance
    • Townsend DM, Tew KD: The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 22:7369-7375, 2003
    • (2003) Oncogene , vol.22 , pp. 7369-7375
    • Townsend, D.M.1    Tew, K.D.2
  • 7
    • 0023157369 scopus 로고
    • Hepatic drug-metabolising enzymes in primary and secondary tumours of human liver
    • El Mouelhi M, Didolkar MS, Elias G, et al: Hepatic drug-metabolising enzymes in primary and secondary tumours of human liver. Cancer Res 47:460-466, 1987
    • (1987) Cancer Res , vol.47 , pp. 460-466
    • El Mouelhi, M.1    Didolkar, M.S.2    Elias, G.3
  • 8
    • 0023951396 scopus 로고
    • Roles of cytochrome P450 enzymes in chemical carcinogenesis and cancer chemotherapy
    • Guengerich FP: Roles of cytochrome P450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res 48:2946-2954, 1988
    • (1988) Cancer Res , vol.48 , pp. 2946-2954
    • Guengerich, F.P.1
  • 9
    • 0025757011 scopus 로고
    • Comparison of levels of several human microsomal cytochrome P450 enzymes and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples
    • Guengerich FP, Turvey CG: Comparison of levels of several human microsomal cytochrome P450 enzymes and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples. J Pharm Exp Ther 256:1189-1193, 1991
    • (1991) J Pharm Exp Ther , vol.256 , pp. 1189-1193
    • Guengerich, F.P.1    Turvey, C.G.2
  • 10
    • 0036015562 scopus 로고    scopus 로고
    • Tumour cytochrome P450 and drug activation
    • Patterson LH, Murray GI: Tumour cytochrome P450 and drug activation. Curr Pharm Des 8:1335-1347, 2002
    • (2002) Curr Pharm Des , vol.8 , pp. 1335-1347
    • Patterson, L.H.1    Murray, G.I.2
  • 11
    • 0035977862 scopus 로고    scopus 로고
    • Genetic variability in susceptibility and response to toxicants
    • Ingelman-Sundberb M: Genetic variability in susceptibility and response to toxicants. Toxicol Lett 120:259-268, 2001
    • (2001) Toxicol Lett , vol.120 , pp. 259-268
    • Ingelman-Sundberb, M.1
  • 12
    • 0035692767 scopus 로고    scopus 로고
    • Polymorphisms of metabolizing enzymes and transporter proteins involved in the clearance of anticancer agents
    • Sekine I, Saijo N: Polymorphisms of metabolizing enzymes and transporter proteins involved in the clearance of anticancer agents. Ann Oncol 12:1515-1525, 2001
    • (2001) Ann Oncol , vol.12 , pp. 1515-1525
    • Sekine, I.1    Saijo, N.2
  • 13
    • 0021778327 scopus 로고
    • The isoenzymes of glutathione-s-transferase
    • Mannervik B: The isoenzymes of glutathione-s-transferase. Adv Enzymol 57:357-417, 1985
    • (1985) Adv Enzymol , vol.57 , pp. 357-417
    • Mannervik, B.1
  • 14
    • 0035476887 scopus 로고    scopus 로고
    • Polymorphisms in glutathione S-transferases (GSTMI and GSTT1) and survival after treatment for breast caner
    • Ambrosone CB, Sweeney C, Coles BF, et al: Polymorphisms in glutathione S-transferases (GSTMI and GSTT1) and survival after treatment for breast caner. Cancer Res 61:7130-7135, 2001
    • (2001) Cancer Res , vol.61 , pp. 7130-7135
    • Ambrosone, C.B.1    Sweeney, C.2    Coles, B.F.3
  • 15
    • 0033104667 scopus 로고    scopus 로고
    • Regulation and function of family 1 and family 2 UDP- glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus
    • Strassburg CP, Strassburg A, Nguyen N, et al: Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus. Biochem J 338:489-498, 1999
    • (1999) Biochem J , vol.338 , pp. 489-498
    • Strassburg, C.P.1    Strassburg, A.2    Nguyen, N.3
  • 16
    • 0036765309 scopus 로고    scopus 로고
    • Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38)
    • Gagne J-F, Montminy V, Belanger P, et al: Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38). Mol Pharmacol 62:608-617, 2002
    • (2002) Mol Pharmacol , vol.62 , pp. 608-617
    • Gagne, J.-F.1    Montminy, V.2    Belanger, P.3
  • 17
    • 0030958469 scopus 로고    scopus 로고
    • Multienzyme-mediated stable and transient multidrug resistance and collateral sensitivity induced by xenobiotics
    • Rekha GK, Sladek NE: Multienzyme-mediated stable and transient multidrug resistance and collateral sensitivity induced by xenobiotics. Cancer Chemother Pharmacol 40:215-224, 1997
    • (1997) Cancer Chemother Pharmacol , vol.40 , pp. 215-224
    • Rekha, G.K.1    Sladek, N.E.2
  • 18
    • 0033668698 scopus 로고    scopus 로고
    • The role of cytochrome P450 in tumour development and progression and its potential in therapy
    • Murray GI: The role of cytochrome P450 in tumour development and progression and its potential in therapy. J Pathol 192:419-426, 2000
    • (2000) J Pathol , vol.192 , pp. 419-426
    • Murray, G.I.1
  • 19
    • 0035210464 scopus 로고    scopus 로고
    • The MRP family and anticancer drug metabolism
    • Suzuki T, Nisho K, Tanabe S: The MRP family and anticancer drug metabolism. Curr Drug Metab, 2:367-377, 2001
    • (2001) Curr Drug Metab , vol.2 , pp. 367-377
    • Suzuki, T.1    Nisho, K.2    Tanabe, S.3
  • 20
    • 0037045583 scopus 로고    scopus 로고
    • BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to ST1571: A prospective study
    • von Bubnoff N, Schneller F, Peschel C, et al: BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to ST1571: A prospective study. Lancet 359:487-491, 2002
    • (2002) Lancet , vol.359 , pp. 487-491
    • Von Bubnoff, N.1    Schneller, F.2    Peschel, C.3
  • 21
    • 0031960619 scopus 로고    scopus 로고
    • Tumor resistance to antimetabolites
    • Kinsella AR, Smith D: Tumor resistance to antimetabolites. Gen Pharm 30:623-626, 1998
    • (1998) Gen Pharm , vol.30 , pp. 623-626
    • Kinsella, A.R.1    Smith, D.2
  • 22
    • 0035802180 scopus 로고    scopus 로고
    • Cancer, DNA repair mechanisms, and resistance to chemotherapy
    • Fojo T: Cancer, DNA repair mechanisms, and resistance to chemotherapy. J Natl Cancer Inst 93:1434-1436, 2001
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1434-1436
    • Fojo, T.1
  • 23
    • 0035142865 scopus 로고    scopus 로고
    • Human CYP1B1 and anticancer agent metabolism: Mechanism for tumor-specific drug inactivation?
    • Rochat B, Morsman JM, Murray GI, et al: Human CYP1B1 and anticancer agent metabolism: Mechanism for tumor-specific drug inactivation? J Pharmacol Exp Ther 296:537-541, 2001
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 537-541
    • Rochat, B.1    Morsman, J.M.2    Murray, G.I.3
  • 24
    • 0034016415 scopus 로고    scopus 로고
    • Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients
    • Schuler J, Cassidy J, Dumont E, et al: Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients. Cancer Chemother Pharmacol 45:291-297, 2000
    • (2000) Cancer Chemother Pharmacol , vol.45 , pp. 291-297
    • Schuler, J.1    Cassidy, J.2    Dumont, E.3
  • 25
    • 0030810198 scopus 로고    scopus 로고
    • Potentiation of cytochrome P450/cyclophosphamide-based cancer gene therapy by coexpression of the p450 reductase gene
    • Chen L, Yu LJ, Waxman DJ: Potentiation of cytochrome P450/ cyclophosphamide-based cancer gene therapy by coexpression of the p450 reductase gene. Cancer Res 57:4830-4837, 1997
    • (1997) Cancer Res , vol.57 , pp. 4830-4837
    • Chen, L.1    Yu, L.J.2    Waxman, D.J.3
  • 26
    • 0034885956 scopus 로고    scopus 로고
    • Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors
    • Huang Z, Waxman DJ: Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors. Cancer Gene Ther 8:450-458, 2001
    • (2001) Cancer Gene Ther , vol.8 , pp. 450-458
    • Huang, Z.1    Waxman, D.J.2
  • 27
    • 0032827040 scopus 로고    scopus 로고
    • Recent developments in gene-directed enzyme prodrug therapy (GDEPT) for cancer
    • Niculescu-Duvaz I, Cooper RG, Stribbling SM, et al: Recent developments in gene-directed enzyme prodrug therapy (GDEPT) for cancer. Curr Opin Mol Ther 1:480-486, 1999
    • (1999) Curr Opin Mol Ther , vol.1 , pp. 480-486
    • Niculescu-Duvaz, I.1    Cooper, R.G.2    Stribbling, S.M.3
  • 28
    • 0032901285 scopus 로고    scopus 로고
    • Cytochrome P450-based cancer gene therapy: Recent advances and future prospects
    • Waxman DJ, Chen L, Hecht JED, et al: Cytochrome P450-based cancer gene therapy: Recent advances and future prospects. Drug Metab Rev 31:503-522, 1999
    • (1999) Drug Metab Rev , vol.31 , pp. 503-522
    • Waxman, D.J.1    Chen, L.2    Hecht, J.E.D.3
  • 29
    • 0026794283 scopus 로고
    • Specific activation of glucuronide prodrugs by antibody-targeted enzyme conjugates for cancer therapy
    • Wang S-M, Chern J-W, Yeh M-Y, et al: Specific activation of glucuronide prodrugs by antibody-targeted enzyme conjugates for cancer therapy. Cancer Res 52:4484-4491, 1992
    • (1992) Cancer Res , vol.52 , pp. 4484-4491
    • Wang, S.-M.1    Chern, J.-W.2    Yeh, M.-Y.3
  • 30
    • 0036307898 scopus 로고    scopus 로고
    • Limited penetration of anticancer drugs through tumor tissue: A potential cause of resistance of solid tumors to chemotherapy
    • Tannock IF, Lee CM, Tunggal JK, et al: Limited penetration of anticancer drugs through tumor tissue: A potential cause of resistance of solid tumors to chemotherapy. Clin Cancer Res 8:878-884, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 878-884
    • Tannock, I.F.1    Lee, C.M.2    Tunggal, J.K.3
  • 31
    • 0032053823 scopus 로고    scopus 로고
    • The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
    • Brown JM, Giaccia AJ: The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy. Cancer Res 58:1408-1416, 1998
    • (1998) Cancer Res , vol.58 , pp. 1408-1416
    • Brown, J.M.1    Giaccia, A.J.2
  • 32
    • 0034660849 scopus 로고    scopus 로고
    • Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy
    • Jounaidi Y, Waxman DJ: Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy. Cancer Res 60:3761-3769, 2000
    • (2000) Cancer Res , vol.60 , pp. 3761-3769
    • Jounaidi, Y.1    Waxman, D.J.2
  • 33
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE: Multidrug resistance in cancer: Role of ATP-dependent transporters. Nat Rev Cancer 2:48-58, 2002
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 34
    • 0345724724 scopus 로고    scopus 로고
    • The MRP family of drug efflux pumps
    • Kruh GD, Belinsky MG: The MRP family of drug efflux pumps. Oncogene 22:7537-7552, 2003
    • (2003) Oncogene , vol.22 , pp. 7537-7552
    • Kruh, G.D.1    Belinsky, M.G.2
  • 35
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • Borst P, Evers R, Kool M, et al: A family of drug transporters: The multidrug resistance-associated proteins. J Natl Cancer Inst 92:1295-1302, 2000
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3
  • 36
    • 0042531890 scopus 로고    scopus 로고
    • MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′,3′- dideoxycytidine and 9′-(2′-phosphonylmethoxyethyl)adenine
    • Guo Y, Kotova E, Chen ZS, et al: MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′,3′-dideoxycytidine and 9′-(2′- phosphonylmethoxyethyl)adenine. J Biol Chem 278:29509-29514, 2003
    • (2003) J Biol Chem , vol.278 , pp. 29509-29514
    • Guo, Y.1    Kotova, E.2    Chen, Z.S.3
  • 37
    • 0345688604 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
    • Doyle LA, Ross DD: Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2). Oncogene 22:7340-7358, 2003
    • (2003) Oncogene , vol.22 , pp. 7340-7358
    • Doyle, L.A.1    Ross, D.D.2
  • 38
    • 0345688213 scopus 로고    scopus 로고
    • Vaults: A ribonucleoprotein particle involved in drug resistance?
    • Mossink MH, van Zon A, Scheper RJ, et al: Vaults: A ribonucleoprotein particle involved in drug resistance? Oncogene 22:7458-7467, 2003
    • (2003) Oncogene , vol.22 , pp. 7458-7467
    • Mossink, M.H.1    Van Zon, A.2    Scheper, R.J.3
  • 39
    • 0031765907 scopus 로고    scopus 로고
    • Role of P-glycoprotein and cytochrome P4503A in limiting oral absorption of peptides and peptidomimetic
    • Wacher VJ, Silverman JA, Zhang Y, et al: Role of P-glycoprotein and cytochrome P4503A in limiting oral absorption of peptides and peptidomimetic. J Pharm Sci 87:1322-1330, 1998
    • (1998) J Pharm Sci , vol.87 , pp. 1322-1330
    • Wacher, V.J.1    Silverman, J.A.2    Zhang, Y.3
  • 40
    • 0032907322 scopus 로고    scopus 로고
    • Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein
    • Kim RB, Wandel C, Leake B, et al: Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. Pharm Res 16:408-414, 1999
    • (1999) Pharm Res , vol.16 , pp. 408-414
    • Kim, R.B.1    Wandel, C.2    Leake, B.3
  • 42
    • 0034721159 scopus 로고    scopus 로고
    • Humanized xenobiotic response in mice expressing nuclear receptor SXR
    • Xie W, Barwick JL, Downes M, et al: Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature 406:435-439, 2000
    • (2000) Nature , vol.406 , pp. 435-439
    • Xie, W.1    Barwick, J.L.2    Downes, M.3
  • 43
    • 0035038919 scopus 로고    scopus 로고
    • The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
    • Synold TW, Dussault I, Forman BM: The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med 7:584-590, 2001
    • (2001) Nat Med , vol.7 , pp. 584-590
    • Synold, T.W.1    Dussault, I.2    Forman, B.M.3
  • 44
    • 0032807743 scopus 로고    scopus 로고
    • The human orphan receptor PXR messenger RNA is expressed in both normal and neoplastic breast tissue
    • Dotzlaw H, Leygue E, Watson P, et al: The human orphan receptor PXR messenger RNA is expressed in both normal and neoplastic breast tissue. Clin Cancer Res 5:2103-2107, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 2103-2107
    • Dotzlaw, H.1    Leygue, E.2    Watson, P.3
  • 45
    • 0037252475 scopus 로고    scopus 로고
    • Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines
    • Pfrunder A, Gutmann H, Beglinger C, et al: Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines. J Pharm Pharmacol 55:59-66, 2003
    • (2003) J Pharm Pharmacol , vol.55 , pp. 59-66
    • Pfrunder, A.1    Gutmann, H.2    Beglinger, C.3
  • 46
    • 0038029586 scopus 로고    scopus 로고
    • Steroid and xenobiotic receptor (SXR) is a key system for the acquisition of cisplatin resistance in endometrial cancer cells
    • Takami N, Sakamoto H, Yamamoto T: Steroid and xenobiotic receptor (SXR) is a key system for the acquisition of cisplatin resistance in endometrial cancer cells. J Int Med Res 31:59-68, 2003
    • (2003) J Int Med Res , vol.31 , pp. 59-68
    • Takami, N.1    Sakamoto, H.2    Yamamoto, T.3
  • 47
    • 0030812372 scopus 로고    scopus 로고
    • Tumor-specific expression of cytochrome P450 CYP1B1
    • Murray GI, Taylor MC, McFadyen MC, et al: Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res 57:3026-3031, 1997
    • (1997) Cancer Res , vol.57 , pp. 3026-3031
    • Murray, G.I.1    Taylor, M.C.2    McFadyen, M.C.3
  • 48
    • 0027203699 scopus 로고
    • Main drug-metabolizing enzyme systems in human breast tumors and peritumoral tissues
    • Albin N, Massaad L, Toussaint C, et al: Main drug-metabolizing enzyme systems in human breast tumors and peritumoral tissues. Cancer Res 53:3541-3546, 1993
    • (1993) Cancer Res , vol.53 , pp. 3541-3546
    • Albin, N.1    Massaad, L.2    Toussaint, C.3
  • 49
    • 0029834242 scopus 로고    scopus 로고
    • Expression of cytochromes P450 in human breast tissue and tumors
    • Huang Z, Fasco MJ, Figge HL, et al: Expression of cytochromes P450 in human breast tissue and tumors. Drug Metab Dispos 24:899-905, 1996
    • (1996) Drug Metab Dispos , vol.24 , pp. 899-905
    • Huang, Z.1    Fasco, M.J.2    Figge, H.L.3
  • 50
    • 0036202207 scopus 로고    scopus 로고
    • Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: A retrospective study-Rational individualization of oxazaphosphorine-based cancer chemotherapeutic regimens
    • Sladek NE, Kollander R, Sreerama L, et al: Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: A retrospective study-Rational individualization of oxazaphosphorine-based cancer chemotherapeutic regimens. Cancer Chemother Pharmacol 49:309-321, 2002
    • (2002) Cancer Chemother Pharmacol , vol.49 , pp. 309-321
    • Sladek, N.E.1    Kollander, R.2    Sreerama, L.3
  • 51
    • 0034743363 scopus 로고    scopus 로고
    • Primary breast tumor levels of suspected molecular determinants of cellular sensitivity to cyclophosphamide, ifosfamide, and certain other anticancer agents as predictors of paired metastatic tumor levels of these determinants: Rational individualization of cancer chemotherapeutic regimens
    • Sreerama L, Sladek N: Primary breast tumor levels of suspected molecular determinants of cellular sensitivity to cyclophosphamide, ifosfamide, and certain other anticancer agents as predictors of paired metastatic tumor levels of these determinants: Rational individualization of cancer chemotherapeutic regimens. Cancer Chemother Pharmacol 47:255-262, 2001
    • (2001) Cancer Chemother Pharmacol , vol.47 , pp. 255-262
    • Sreerama, L.1    Sladek, N.2
  • 52
    • 0034672381 scopus 로고    scopus 로고
    • Increased expression of cytochrome P450 1A1 and 1B1 genes in anti-oestrogen-resistant human breast cancer cell lines
    • Brockdorff BL, Skouv J, Reiter BE, et al: Increased expression of cytochrome P450 1A1 and 1B1 genes in anti-oestrogen-resistant human breast cancer cell lines. Int J Cancer 88:902-906, 2000
    • (2000) Int J Cancer , vol.88 , pp. 902-906
    • Brockdorff, B.L.1    Skouv, J.2    Reiter, B.E.3
  • 53
    • 0027288746 scopus 로고
    • Regulation of cytochrome P450 gene expression in human colon and breast xenografts
    • Smith G, Harrison DJ, East N, et al: Regulation of cytochrome P450 gene expression in human colon and breast xenografts. Br J Cancer 68:57-63, 1993
    • (1993) Br J Cancer , vol.68 , pp. 57-63
    • Smith, G.1    Harrison, D.J.2    East, N.3
  • 54
    • 0029865150 scopus 로고    scopus 로고
    • 4-Hydroxylation of estrogens as marker of human mammary tumors
    • Liehr JG, Ricci MJ: 4-Hydroxylation of estrogens as marker of human mammary tumors. Proc Natl Acad Sci 93:3294-3296, 1996
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 3294-3296
    • Liehr, J.G.1    Ricci, M.J.2
  • 55
    • 18244374492 scopus 로고    scopus 로고
    • Prognostic significance of dihydropyrimidine dehydrogenase expression in breast cancer
    • Horiguchi J, Takai H, Koibuchi Y, et al: Prognostic significance of dihydropyrimidine dehydrogenase expression in breast cancer. Br J Cancer 86:222-225, 2002
    • (2002) Br J Cancer , vol.86 , pp. 222-225
    • Horiguchi, J.1    Takai, H.2    Koibuchi, Y.3
  • 56
    • 0030768982 scopus 로고    scopus 로고
    • DT-diaphorase and cytochrome B5 reductase in human lung and breast tumours
    • Marin A, Lopez de Cerain A, Hamilton E, et al: DT-diaphorase and cytochrome B5 reductase in human lung and breast tumours. Br J Cancer 76:923-929, 1997
    • (1997) Br J Cancer , vol.76 , pp. 923-929
    • Marin, A.1    Lopez De Cerain, A.2    Hamilton, E.3
  • 57
    • 18244390013 scopus 로고    scopus 로고
    • Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cells human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas
    • Nakamura T, Sakaeda T, Ohmoto N, et al: Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cells human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas. Drug Metab Dispos 30:4-6, 2002
    • (2002) Drug Metab Dispos , vol.30 , pp. 4-6
    • Nakamura, T.1    Sakaeda, T.2    Ohmoto, N.3
  • 58
    • 0031906566 scopus 로고    scopus 로고
    • Enhanced expression of cytochrome P450 in stomach cancer
    • Murray GI, Taylor MC, Burke M: D, et al: Enhanced expression of cytochrome P450 in stomach cancer. Br J Cancer 77:1040-1044, 1998
    • (1998) Br J Cancer , vol.77 , pp. 1040-1044
    • Murray, G.I.1    Taylor, M.C.2    Burke, M.D.3
  • 59
    • 0026464753 scopus 로고
    • Comparison of mouse and human colon tumors with regard to phase I and phase II drug-metabolising enzyme systems
    • Massaad L, de Waziers I, Ribrag V, et al: Comparison of mouse and human colon tumors with regard to phase I and phase II drug-metabolising enzyme systems. Cancer Res 52:6567-6575, 1992
    • (1992) Cancer Res , vol.52 , pp. 6567-6575
    • Massaad, L.1    De Waziers, I.2    Ribrag, V.3
  • 60
    • 0035888165 scopus 로고    scopus 로고
    • Thymidine phosphorylase and dihydropyrimidine dehydrogenase protein expression in colorectal cancer
    • Collie-Duguid E, Johnston SJ, Boyce L, et al: Thymidine phosphorylase and dihydropyrimidine dehydrogenase protein expression in colorectal cancer. Int J Cancer 94:297-301, 2001
    • (2001) Int J Cancer , vol.94 , pp. 297-301
    • Collie-Duguid, E.1    Johnston, S.J.2    Boyce, L.3
  • 61
    • 0032862086 scopus 로고    scopus 로고
    • Regulation of dihydropyrimidine dehydrogenase in colorectal cancer
    • Johnston SJ, Ridge SA, Cassidy J, et al: Regulation of dihydropyrimidine dehydrogenase in colorectal cancer. Clin Cancer Res 5:2566-2570, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 2566-2570
    • Johnston, S.J.1    Ridge, S.A.2    Cassidy, J.3
  • 62
    • 0028315963 scopus 로고
    • Quantification of CYP2B7, CYP4B1, and CYPOR messenger RNAs in normal human lung and lung tumors
    • Czerwinski M, McLemore TL, Gelboin HV, et al: Quantification of CYP2B7, CYP4B1, and CYPOR messenger RNAs in normal human lung and lung tumors. Cancer Res 54:1085-1091, 1994
    • (1994) Cancer Res , vol.54 , pp. 1085-1091
    • Czerwinski, M.1    McLemore, T.L.2    Gelboin, H.V.3
  • 63
    • 0034913356 scopus 로고    scopus 로고
    • Induction of cytochrome P450 3A4 by docetaxel in peripheral mononuclear cells and its expression in lung cancer
    • Fujitaka K, Oguri T, Isobe T, et al: Induction of cytochrome P450 3A4 by docetaxel in peripheral mononuclear cells and its expression in lung cancer. Cancer Chemother Pharmacol 48:42-46, 2001
    • (2001) Cancer Chemother Pharmacol , vol.48 , pp. 42-46
    • Fujitaka, K.1    Oguri, T.2    Isobe, T.3
  • 64
    • 0027361057 scopus 로고
    • Main drug-and carcinogen-metabolizing enzyme systems in human non-small cell lung cancer and peritumoral tissues
    • Troussaint C, Albin N, Massaad L, et al: Main drug-and carcinogen-metabolizing enzyme systems in human non-small cell lung cancer and peritumoral tissues. Cancer Res 53:4608-4612, 1993
    • (1993) Cancer Res , vol.53 , pp. 4608-4612
    • Troussaint, C.1    Albin, N.2    Massaad, L.3
  • 65
    • 0025333934 scopus 로고
    • The human CYP2F gene subfamily: Identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping
    • Nhamburo PT, Kimura S, McBride OW, et al: The human CYP2F gene subfamily: Identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping. Biochemistry 29:5491-5499, 1990
    • (1990) Biochemistry , vol.29 , pp. 5491-5499
    • Nhamburo, P.T.1    Kimura, S.2    McBride, O.W.3
  • 66
    • 0034758473 scopus 로고    scopus 로고
    • Thymidylate synthetase and dihydropyrimidine dehydrogenase activities in non-small cell lung cancer tissues: Relationship with in vitro sensitivity to 5-fluorouracil
    • Higashiyama M, Kodama K, Yokouchi H, et al: Thymidylate synthetase and dihydropyrimidine dehydrogenase activities in non-small cell lung cancer tissues: Relationship with in vitro sensitivity to 5-fluorouracil. Lung Cancer 34:407-416, 2001
    • (2001) Lung Cancer , vol.34 , pp. 407-416
    • Higashiyama, M.1    Kodama, K.2    Yokouchi, H.3
  • 67
    • 0029164768 scopus 로고
    • Main drug-metabolizing enzyme systems in human non-Hodgkin's lymphomas sensitive or resistant to chemotherapy
    • Ribrag V, Massaad L, Janot F, et al: Main drug-metabolizing enzyme systems in human non-Hodgkin's lymphomas sensitive or resistant to chemotherapy. Leuk Lymphoma 18:303-310, 1995
    • (1995) Leuk Lymphoma , vol.18 , pp. 303-310
    • Ribrag, V.1    Massaad, L.2    Janot, F.3
  • 68
    • 0036512763 scopus 로고    scopus 로고
    • Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines
    • Nagai F, Hiyoshi Y, Sugimachi K, et al: Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines. Biol Pharm Bull 25:383-385, 2002
    • (2002) Biol Pharm Bull , vol.25 , pp. 383-385
    • Nagai, F.1    Hiyoshi, Y.2    Sugimachi, K.3
  • 69
    • 0021037057 scopus 로고
    • Mixed function oxidase enzymes in human normal granulocytes and chronic myeloid leukemia cells, I: Detection and Estimation
    • Mungikar AM, Zingde SM, Advabr SH, et al: Mixed function oxidase enzymes in human normal granulocytes and chronic myeloid leukemia cells, I: Detection and Estimation. Biochem Med 30:181-187, 1983
    • (1983) Biochem Med , vol.30 , pp. 181-187
    • Mungikar, A.M.1    Zingde, S.M.2    Advabr, S.H.3
  • 70
    • 0037047701 scopus 로고    scopus 로고
    • Effect of cyclophosphamide on gene expression of cytochromes p450 and beta-actin in the HL-60 cell line
    • Xie HJ, Lundgren S, Broberg U, et al: Effect of cyclophosphamide on gene expression of cytochromes p450 and beta-actin in the HL-60 cell line. Eur J Pharmacol 449:197-205, 2002
    • (2002) Eur J Pharmacol , vol.449 , pp. 197-205
    • Xie, H.J.1    Lundgren, S.2    Broberg, U.3
  • 71
    • 0033972055 scopus 로고    scopus 로고
    • Multiple forms of cytochrome P450 and associated monooxygenase activities in human brain mitochondria
    • Bhagwat SV, Boyd MR, Ravindranath V: Multiple forms of cytochrome P450 and associated monooxygenase activities in human brain mitochondria. Biochem Pharmacol 59:573-582, 2000
    • (2000) Biochem Pharmacol , vol.59 , pp. 573-582
    • Bhagwat, S.V.1    Boyd, M.R.2    Ravindranath, V.3
  • 72
    • 0035198175 scopus 로고    scopus 로고
    • The expression of P450 enzymes in human breast tumours and normal breast tissue
    • Iscan M, Klaavuniemi T, Coban T, et al: The expression of P450 enzymes in human breast tumours and normal breast tissue. Breast Cancer Res Treat 70:47-54, 2001
    • (2001) Breast Cancer Res Treat , vol.70 , pp. 47-54
    • Iscan, M.1    Klaavuniemi, T.2    Coban, T.3
  • 73
    • 0041922374 scopus 로고    scopus 로고
    • Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR
    • Nishimura M, Yaguti H, Yoshitsugu H, et al: Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR. Yakugaku Zasshi 123:369-375, 2003
    • (2003) Yakugaku Zasshi , vol.123 , pp. 369-375
    • Nishimura, M.1    Yaguti, H.2    Yoshitsugu, H.3
  • 74
    • 0036561247 scopus 로고    scopus 로고
    • Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR
    • Nishimura M, Yoshitsugu H, Naito S, et al: Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR. Yakugaku Zasshi 122:339-361, 2002
    • (2002) Yakugaku Zasshi , vol.122 , pp. 339-361
    • Nishimura, M.1    Yoshitsugu, H.2    Naito, S.3
  • 75
    • 0037441744 scopus 로고    scopus 로고
    • Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia
    • Stam RW, den Boer ML, Meijerink JP, et al: Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia. Blood 101:1270-1276, 2003
    • (2003) Blood , vol.101 , pp. 1270-1276
    • Stam, R.W.1    Den Boer, M.L.2    Meijerink, J.P.3
  • 76
    • 0023061373 scopus 로고
    • P450 genes: Structure, evolution and regulation
    • Nebert DW, Gonzalez FJ: P450 genes: Structure, evolution and regulation. Annu Rev Biochem 56:945-993, 1987
    • (1987) Annu Rev Biochem , vol.56 , pp. 945-993
    • Nebert, D.W.1    Gonzalez, F.J.2
  • 77
    • 0036325773 scopus 로고    scopus 로고
    • Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: Formation of the 4-hydroxy, 4′-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen
    • Crewe HK, Notley LM, Wunsch RM, et al: Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: Formation of the 4-hydroxy, 4′-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen. Drug Metab Dispos 30:869-874, 2002
    • (2002) Drug Metab Dispos , vol.30 , pp. 869-874
    • Crewe, H.K.1    Notley, L.M.2    Wunsch, R.M.3
  • 78
    • 0028272001 scopus 로고
    • Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
    • Gonzalez FJ, Gelboin HV: Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab Rev 26:165-183, 1994
    • (1994) Drug Metab Rev , vol.26 , pp. 165-183
    • Gonzalez, F.J.1    Gelboin, H.V.2
  • 79
    • 0035879957 scopus 로고    scopus 로고
    • Cytochrome P450 CYP1B1 protein expression: A novel mechanism of anticancer drug resistance
    • McFadyen MC, McLeod HL, Jackson FC, et al: Cytochrome P450 CYP1B1 protein expression: A novel mechanism of anticancer drug resistance. Biochem Pharmacol 62:207-212, 2001
    • (2001) Biochem Pharmacol , vol.62 , pp. 207-212
    • McFadyen, M.C.1    McLeod, H.L.2    Jackson, F.C.3
  • 80
    • 0032937986 scopus 로고    scopus 로고
    • The physiological and pharmacological roles of cytochrome P450 isoenzymes
    • Chang GWM, Kam PCA: The physiological and pharmacological roles of cytochrome P450 isoenzymes. Anesthesia 54:42-50, 1999
    • (1999) Anesthesia , vol.54 , pp. 42-50
    • Chang, G.W.M.1    Kam, P.C.A.2
  • 81
    • 0033051029 scopus 로고    scopus 로고
    • Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles
    • Roy P, Yu LJ, Crespi CL, et al: Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles. Drug Metab Dispos 27:655-666, 1999
    • (1999) Drug Metab Dispos , vol.27 , pp. 655-666
    • Roy, P.1    Yu, L.J.2    Crespi, C.L.3
  • 82
    • 1642353685 scopus 로고    scopus 로고
    • CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes
    • Schmidt R, Baumann F, Knupfer H, et al: CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes. Br J Cancer 90:911-916, 2004
    • (2004) Br J Cancer , vol.90 , pp. 911-916
    • Schmidt, R.1    Baumann, F.2    Knupfer, H.3
  • 83
    • 0037652178 scopus 로고    scopus 로고
    • Cytochrome p450 and glutathione transferase expression in human breast cancer
    • El-Rayes BF, Ali S, Heilbrun LK, et al: Cytochrome p450 and glutathione transferase expression in human breast cancer. Clin Cancer Res 9:1705-1709, 2003
    • (2003) Clin Cancer Res , vol.9 , pp. 1705-1709
    • El-Rayes, B.F.1    Ali, S.2    Heilbrun, L.K.3
  • 84
    • 0032960670 scopus 로고    scopus 로고
    • Characterization of cytochrome P450 expression in human oesophageal mucosa
    • Lechevrel M, Casson AG, Wolf CR, et al: Characterization of cytochrome P450 expression in human oesophageal mucosa. Carcinogenesis 20:243-248, 1999
    • (1999) Carcinogenesis , vol.20 , pp. 243-248
    • Lechevrel, M.1    Casson, A.G.2    Wolf, C.R.3
  • 85
    • 0034792584 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
    • Goldstein JA: Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. Br J Clin Pharmacol 52:349-355, 2001
    • (2001) Br J Clin Pharmacol , vol.52 , pp. 349-355
    • Goldstein, J.A.1
  • 86
    • 0028036727 scopus 로고
    • Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8
    • Rahman A, Korzekwa KR, Grogan J, et al: Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8. Cancer Res 54:5543-5546, 1994
    • (1994) Cancer Res , vol.54 , pp. 5543-5546
    • Rahman, A.1    Korzekwa, K.R.2    Grogan, J.3
  • 87
    • 0034791777 scopus 로고    scopus 로고
    • Polymorphisms in human CYP2C8 decrease: Metabolism of the anticancer drug paclitaxel and arachidonic acid
    • Dai D, Zeldin DC, Blaisdell JA, et al: Polymorphisms in human CYP2C8 decrease: Metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 11:597-607, 2001
    • (2001) Pharmacogenetics , vol.11 , pp. 597-607
    • Dai, D.1    Zeldin, D.C.2    Blaisdell, J.A.3
  • 88
    • 0031892907 scopus 로고    scopus 로고
    • Modification of paclitaxel metabolism in a cancer patient by induction of cytochrome P450 3A4
    • Monsarrat B, Chatelut E, Royer I, et al: Modification of paclitaxel metabolism in a cancer patient by induction of cytochrome P450 3A4. Drug Metab Dispos 26:229-233, 1998
    • (1998) Drug Metab Dispos , vol.26 , pp. 229-233
    • Monsarrat, B.1    Chatelut, E.2    Royer, I.3
  • 89
    • 0036285336 scopus 로고    scopus 로고
    • Thalidomide metabolism by the CYP2C subfamily
    • Ando Y, Fuse E, Figg WD: Thalidomide metabolism by the CYP2C subfamily. Clin Cancer Res 8:1964-1973, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 1964-1973
    • Ando, Y.1    Fuse, E.2    Figg, W.D.3
  • 90
    • 0037974540 scopus 로고    scopus 로고
    • Pharmacogenetic associations of CYP2C19 genotype with in vivo metabolisms and pharmacological effects of thalidomide
    • Ando Y, Price DK, Dahut WL, et al: Pharmacogenetic associations of CYP2C19 genotype with in vivo metabolisms and pharmacological effects of thalidomide. Cancer Biol Ther 1:669-673, 2002
    • (2002) Cancer Biol Ther , vol.1 , pp. 669-673
    • Ando, Y.1    Price, D.K.2    Dahut, W.L.3
  • 91
    • 0037048285 scopus 로고    scopus 로고
    • Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: Implications for drug therapy
    • Martinez C, Garcia-Martin E, Pizarro RM, et al: Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: Implications for drug therapy. Br J Cancer 87:681-686, 2002
    • (2002) Br J Cancer , vol.87 , pp. 681-686
    • Martinez, C.1    Garcia-Martin, E.2    Pizarro, R.M.3
  • 92
    • 0037131879 scopus 로고    scopus 로고
    • Genetic contribution to variable human CYP3A-mediated metabolism
    • Lamba JK, Lin YS, Schuetz EG, et al: Genetic contribution to variable human CYP3A-mediated metabolism. Adv Drug Deliv Rev 54:1271-1294, 2002
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1271-1294
    • Lamba, J.K.1    Lin, Y.S.2    Schuetz, E.G.3
  • 94
    • 0036016319 scopus 로고    scopus 로고
    • Novel detection assay by PCR-RFLP and frequency of the CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population
    • Fukuen S, Fukuda T, Maune H, et al: Novel detection assay by PCR-RFLP and frequency of the CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population. Pharmagenomics 12:331-334, 2002
    • (2002) Pharmagenomics , vol.12 , pp. 331-334
    • Fukuen, S.1    Fukuda, T.2    Maune, H.3
  • 95
    • 0033042397 scopus 로고    scopus 로고
    • Cytochrome P450 CYP3A in human renal cell cancer
    • Murray GI, McFadyen MC, Mitchell RT, et al: Cytochrome P450 CYP3A in human renal cell cancer. Br J Cancer 79:1836-1842, 1999
    • (1999) Br J Cancer , vol.79 , pp. 1836-1842
    • Murray, G.I.1    McFadyen, M.C.2    Mitchell, R.T.3
  • 96
    • 0035740051 scopus 로고    scopus 로고
    • Detection of cytochrome P450 mRNA transcripts in prostate samples by RT-PCR
    • Finnstrom N, Bjelfman C, Soderstrom TG, et al: Detection of cytochrome P450 mRNA transcripts in prostate samples by RT-PCR. Eur J Clin Invest 31:880-886, 2001
    • (2001) Eur J Clin Invest , vol.31 , pp. 880-886
    • Finnstrom, N.1    Bjelfman, C.2    Soderstrom, T.G.3
  • 97
    • 28244464534 scopus 로고    scopus 로고
    • CYP3A5*3 and CYP3A4*1B polymorphisms are associated and more frequent in NSCLC tumors than in normal volunteers
    • abstr 2016
    • Kolesar JM, Breunig A, Miller J, et al: CYP3A5*3 and CYP3A4*1B polymorphisms are associated and more frequent in NSCLC tumors than in normal volunteers. Proc Am Soc Clin Oncol 23:131, 2004 (abstr 2016)
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 131
    • Kolesar, J.M.1    Breunig, A.2    Miller, J.3
  • 99
    • 0035103197 scopus 로고    scopus 로고
    • Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members
    • Turgeon D, Carrier JS, Levesque E, et al: Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members. Endocrinology 142:778-787, 2001
    • (2001) Endocrinology , vol.142 , pp. 778-787
    • Turgeon, D.1    Carrier, J.S.2    Levesque, E.3
  • 100
    • 0031756678 scopus 로고    scopus 로고
    • Polymorphic expression the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium
    • Strassburg CP, Nyguyen N, Manns MP, et al: Polymorphic expression the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium. Mol Pharmacol 54:647-654, 1998
    • (1998) Mol Pharmacol , vol.54 , pp. 647-654
    • Strassburg, C.P.1    Nyguyen, N.2    Manns, M.P.3
  • 101
    • 0030790857 scopus 로고    scopus 로고
    • Differential downregualtion of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer
    • Strassburg CP, Manns MP, Tukey RH: Differential downregualtion of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer. Cancer Res 57:2979-2985, 1997
    • (1997) Cancer Res , vol.57 , pp. 2979-2985
    • Strassburg, C.P.1    Manns, M.P.2    Tukey, R.H.3
  • 102
    • 17144458548 scopus 로고    scopus 로고
    • Drug metabolizing enzymes in pharyngeal mucosa and on roopharyngeal cancer tissue
    • Ullrich D, Munzel PA, Beck-Gshaidmeier S, et al: Drug metabolizing enzymes in pharyngeal mucosa and on roopharyngeal cancer tissue. Biochem Pharmacol 54:1159-1162, 1997
    • (1997) Biochem Pharmacol , vol.54 , pp. 1159-1162
    • Ullrich, D.1    Munzel, P.A.2    Beck-Gshaidmeier, S.3
  • 103
    • 0036110301 scopus 로고    scopus 로고
    • Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all-trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast cancers
    • Gestl SA, Green MD, Shearer DA, et al: Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all-trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast cancers. Am J Pathol 160:1467-1479, 2002
    • (2002) Am J Pathol , vol.160 , pp. 1467-1479
    • Gestl, S.A.1    Green, M.D.2    Shearer, D.A.3
  • 104
    • 0029128784 scopus 로고
    • Expression of transcripts encoding steroid UDP-glucuronosyltransferases in human prostate hyperplastic tissue and the LNCaP cell line
    • Belanger G, Beaulieu M, Marcotte B, et al: Expression of transcripts encoding steroid UDP-glucuronosyltransferases in human prostate hyperplastic tissue and the LNCaP cell line. Mol Cell Endocrinol 113:165-173, 1995
    • (1995) Mol Cell Endocrinol , vol.113 , pp. 165-173
    • Belanger, G.1    Beaulieu, M.2    Marcotte, B.3
  • 105
    • 0031764262 scopus 로고    scopus 로고
    • Effect of interleukins on UGT2B15 and UGT2B17 steroid uridine diphosphate-glucuronosyltransferase expression and activity in the LNCaP cell line
    • Levesque E, Beaulieu M, Guillemette C, et al: Effect of interleukins on UGT2B15 and UGT2B17 steroid uridine diphosphate-glucuronosyltransferase expression and activity in the LNCaP cell line. Endocrinology 139:2375-2381, 1998
    • (1998) Endocrinology , vol.139 , pp. 2375-2381
    • Levesque, E.1    Beaulieu, M.2    Guillemette, C.3
  • 106
    • 0030991972 scopus 로고    scopus 로고
    • Differential regulation of two uridine diphospho- glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells
    • Guillemette C, Levesque E, Beaulieu M, et al: Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells. Endocrinology 138:2998-3005, 1997
    • (1997) Endocrinology , vol.138 , pp. 2998-3005
    • Guillemette, C.1    Levesque, E.2    Beaulieu, M.3
  • 107
    • 0031878594 scopus 로고    scopus 로고
    • Human glutathione S-transferase P1 polymorphisms: Relationship to lung tissue enzyme activity and population frequency distribution
    • Watson MA, Stewart RK, Smith GB, et al: Human glutathione S-transferase P1 polymorphisms: Relationship to lung tissue enzyme activity and population frequency distribution. Carcinogenesis 19:275-280, 1998
    • (1998) Carcinogenesis , vol.19 , pp. 275-280
    • Watson, M.A.1    Stewart, R.K.2    Smith, G.B.3
  • 108
    • 0034718294 scopus 로고    scopus 로고
    • Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: A prospective study of men in Shanghai, China
    • London SJ, Yuan JM, Chung FL, et al: Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: A prospective study of men in Shanghai, China. Lancet 356:724-729, 2000
    • (2000) Lancet , vol.356 , pp. 724-729
    • London, S.J.1    Yuan, J.M.2    Chung, F.L.3
  • 109
    • 2042492922 scopus 로고    scopus 로고
    • Association between glutathione-S-transferase GSTP1 genotypes, GSTP1 overexpression, and outcome in epithelial ovarian cancer
    • Howells RE, Dhar KK, Hoban PR, et al: Association between glutathione-S-transferase GSTP1 genotypes, GSTP1 overexpression, and outcome in epithelial ovarian cancer. Int J Gynecol Cancer 14:242-250, 2004
    • (2004) Int J Gynecol Cancer , vol.14 , pp. 242-250
    • Howells, R.E.1    Dhar, K.K.2    Hoban, P.R.3
  • 110
    • 0026019127 scopus 로고
    • Enhanced expression of glutathione S-transferases in colorectal carcinoma compared to non-neoplastic mucosa
    • Moorghen M, Cairns J, Forrester LM, et al: Enhanced expression of glutathione S-transferases in colorectal carcinoma compared to non-neoplastic mucosa. Carcinogenesis 12:13-17, 1991
    • (1991) Carcinogenesis , vol.12 , pp. 13-17
    • Moorghen, M.1    Cairns, J.2    Forrester, L.M.3
  • 111
    • 0028979440 scopus 로고
    • Glutathione S-transferase pi in colorectal tumors is predictive for overall survival
    • Mulder TP, Verspaget HW, Sier CF, et al: Glutathione S-transferase pi in colorectal tumors is predictive for overall survival. Cancer Res 55:2696-2702, 1995
    • (1995) Cancer Res , vol.55 , pp. 2696-2702
    • Mulder, T.P.1    Verspaget, H.W.2    Sier, C.F.3
  • 112
    • 0030596112 scopus 로고    scopus 로고
    • Expression of resistance-related proteins in tumoral and peritumoral tissues of patients with lung cancer
    • Koomagi R, Stammler G, Manegold C, et al: Expression of resistance-related proteins in tumoral and peritumoral tissues of patients with lung cancer. Cancer Lett 110:129-136, 1996
    • (1996) Cancer Lett , vol.110 , pp. 129-136
    • Koomagi, R.1    Stammler, G.2    Manegold, C.3
  • 113
    • 0028068239 scopus 로고
    • Expression of glutathione S-transferase-π and sensitivity of human gastric cancer cells to cisplatin
    • Okuyama T, Maehara Y, Endo K, et al: Expression of glutathione S-transferase-π- and sensitivity of human gastric cancer cells to cisplatin. Cancer 74:1230-1236, 1994
    • (1994) Cancer , vol.74 , pp. 1230-1236
    • Okuyama, T.1    Maehara, Y.2    Endo, K.3
  • 114
    • 18744379728 scopus 로고    scopus 로고
    • Differential gene expression profiles of gastric cancer cells established from primary tumour and malignant ascites
    • Sakakura C, Hagiwara A, Nakanishi M, et al: Differential gene expression profiles of gastric cancer cells established from primary tumour and malignant ascites. Br J Cancer 87:1153-1161, 2002
    • (2002) Br J Cancer , vol.87 , pp. 1153-1161
    • Sakakura, C.1    Hagiwara, A.2    Nakanishi, M.3
  • 115
    • 0035468967 scopus 로고    scopus 로고
    • Aerobic nitroreduction by flavoproteins: Enzyme structure, mechanisms and role in cancer chemotherapy
    • Skelly JV, Knox RJ, Jenkins TC: Aerobic nitroreduction by flavoproteins: Enzyme structure, mechanisms and role in cancer chemotherapy. Mini Rev Med Chem 1:293-306, 2001
    • (2001) Mini Rev Med Chem , vol.1 , pp. 293-306
    • Skelly, J.V.1    Knox, R.J.2    Jenkins, T.C.3
  • 116
    • 0033800627 scopus 로고    scopus 로고
    • The role of NAD(P)H oxidoreductase (DT-diaphorase) in the bioactivation of quinone-containing antitumor agents: A review
    • Gutierrez PL: The role of NAD(P)H oxidoreductase (DT-diaphorase) in the bioactivation of quinone-containing antitumor agents: A review. Free Radic Biol Med 29:263-275, 2000
    • (2000) Free Radic Biol Med , vol.29 , pp. 263-275
    • Gutierrez, P.L.1
  • 117
    • 0036328021 scopus 로고    scopus 로고
    • NAD(P)H: Quinone oxidoreductase enhances proliferation inhibition by 4-hydroxytamoxifen
    • Allen PG, Kolesar JM: NAD(P)H: Quinone oxidoreductase enhances proliferation inhibition by 4-hydroxytamoxifen. Anticancer Res 22:1475-1480, 2002
    • (2002) Anticancer Res , vol.22 , pp. 1475-1480
    • Allen, P.G.1    Kolesar, J.M.2
  • 118
    • 1842841671 scopus 로고    scopus 로고
    • Detection of (NAD(P)H: Quinone oxidoreductase-1, EC 1.6.99.2) 609C->T and 465C->T polymorphisms in formalin-fixed, paraffin-embedded human tumour tissue using PCR-RFLP
    • Phillips RM, Basu S, Brown JE, et al: Detection of (NAD(P)H: Quinone oxidoreductase-1, EC 1.6.99.2) 609C->T and 465C->T polymorphisms in formalin-fixed, paraffin-embedded human tumour tissue using PCR-RFLP. Int J Oncol 24:1005-1010, 2004
    • (2004) Int J Oncol , vol.24 , pp. 1005-1010
    • Phillips, R.M.1    Basu, S.2    Brown, J.E.3
  • 119
    • 0034531564 scopus 로고    scopus 로고
    • NAD(P)H: Quinone oxidoreductase 1 (NQO1): Chemoprotection, bioactivation, gene regulation and genetic polymorphisms
    • Ross D, Kepa JK, Winski SL, et al: NAD(P)H: quinone oxidoreductase 1 (NQO1): Chemoprotection, bioactivation, gene regulation and genetic polymorphisms. Chem Biol Interact 129:77-97, 2000
    • (2000) Chem Biol Interact , vol.129 , pp. 77-97
    • Ross, D.1    Kepa, J.K.2    Winski, S.L.3
  • 120
    • 0242331271 scopus 로고    scopus 로고
    • Differential expression of the antioxidant response element within the hNQO1 promoter in NSCLC versus SCLC
    • Kepa JK, Ross D: Differential expression of the antioxidant response element within the hNQO1 promoter in NSCLC versus SCLC. Biochem Biophys Res Commun 311:446-453, 2003
    • (2003) Biochem Biophys Res Commun , vol.311 , pp. 446-453
    • Kepa, J.K.1    Ross, D.2
  • 121
    • 0036834194 scopus 로고    scopus 로고
    • Evaluation of NQO1 gene expression and variant allele in human NSCLC tumors and matched normal lung tissue
    • Kolesar JM, Pritchard SC, Kerr KM, et al: Evaluation of NQO1 gene expression and variant allele in human NSCLC tumors and matched normal lung tissue. Int J Oncol 21:1119-1124, 2002
    • (2002) Int J Oncol , vol.21 , pp. 1119-1124
    • Kolesar, J.M.1    Pritchard, S.C.2    Kerr, K.M.3
  • 122
    • 12144287215 scopus 로고    scopus 로고
    • Immunohistochemical analysis of NAD(P)H: Quinone oxidoreductase and NADPH cytochrome P450 reductase in human superficial bladder tumours: Relationship between tumour enzymology and clinical outcome following intravesical mitomycin C therapy
    • Basu S, Brown JE, Flannigan GM, et al: Immunohistochemical analysis of NAD(P)H: quinone oxidoreductase and NADPH cytochrome P450 reductase in human superficial bladder tumours: Relationship between tumour enzymology and clinical outcome following intravesical mitomycin C therapy. Int J Cancer 109:703-709, 2004
    • (2004) Int J Cancer , vol.109 , pp. 703-709
    • Basu, S.1    Brown, J.E.2    Flannigan, G.M.3
  • 123
    • 0033801337 scopus 로고    scopus 로고
    • Immunodetection of NAD(P)H: Quinone oxidoreductase 1 (NQO1) in human tissues
    • Siegel D, Ross D: Immunodetection of NAD(P)H: quinone oxidoreductase 1 (NQO1) in human tissues. Free Radic Biol Med 29:246-253, 2000
    • (2000) Free Radic Biol Med , vol.29 , pp. 246-253
    • Siegel, D.1    Ross, D.2
  • 124
    • 0035574464 scopus 로고    scopus 로고
    • Immunohistochemical localization of NAD(P)H: Quinone oxidoreductase in conjunctival melanomas and primary acquired melanosis
    • Wilson MW, Schelonka LP, Siegel D, et al: Immunohistochemical localization of NAD(P)H: quinone oxidoreductase in conjunctival melanomas and primary acquired melanosis. Curr Eye Res 22:348-352, 2001
    • (2001) Curr Eye Res , vol.22 , pp. 348-352
    • Wilson, M.W.1    Schelonka, L.P.2    Siegel, D.3
  • 125
    • 0142027069 scopus 로고    scopus 로고
    • Association between NAD(P)H: Quinone oxidoreductase 1 (NQ01) inactivating C609T polymorphism and adenocarcinoma of the upper gastrointestinal tract
    • Sarbia M, Bitzer M, Siegel D, et al: Association between NAD(P)H: Quinone oxidoreductase 1 (NQ01) inactivating C609T polymorphism and adenocarcinoma of the upper gastrointestinal tract. Int J Cancer 107:381-386, 2003
    • (2003) Int J Cancer , vol.107 , pp. 381-386
    • Sarbia, M.1    Bitzer, M.2    Siegel, D.3
  • 126
    • 0025688249 scopus 로고
    • Metabolism of mitomycin C by DT-diaphorase: Role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells
    • Siegel D, Gibson NW, Preusch PC, et al: Metabolism of mitomycin C by DT-diaphorase: Role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells. Cancer Res 50:7483-7489, 1990
    • (1990) Cancer Res , vol.50 , pp. 7483-7489
    • Siegel, D.1    Gibson, N.W.2    Preusch, P.C.3
  • 127
    • 0025258497 scopus 로고
    • Metabolism of diaziquone by NAD(P)H: (quinone acceptor) oxidoreductase (DT-diaphorase): Role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells
    • Siegel D, Gibson NW, Preusch PC, et al: Metabolism of diaziquone by NAD(P)H: (quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells. Cancer Res 50:7293-7300, 1990
    • (1990) Cancer Res , vol.50 , pp. 7293-7300
    • Siegel, D.1    Gibson, N.W.2    Preusch, P.C.3
  • 128
    • 0031543420 scopus 로고    scopus 로고
    • Studies on the relationship between estrogen receptor content, glutathione S-transferase π expression, and induction by 2,3,7,8- tetrachlorodibenzo-p-dioxin and drug resistance in human breast cancer cells
    • Hoivik D, Wilson C, Wanf W, et al: Studies on the relationship between estrogen receptor content, glutathione S-transferase π expression, and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and drug resistance in human breast cancer cells. Arch Biochem Biophys 348:174-182, 1997
    • (1997) Arch Biochem Biophys , vol.348 , pp. 174-182
    • Hoivik, D.1    Wilson, C.2    Wanf, W.3
  • 129
    • 0035881570 scopus 로고    scopus 로고
    • Dietary indols and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cancer cell lines
    • Bonnesen C, Eggleston IM, Hayes JD, et al: Dietary indols and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cancer cell lines. Cancer Res 61:6120-6130, 2001
    • (2001) Cancer Res , vol.61 , pp. 6120-6130
    • Bonnesen, C.1    Eggleston, I.M.2    Hayes, J.D.3
  • 132
    • 0023752982 scopus 로고
    • Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
    • Huang ME, Ye YC, Chen SR, et al: Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72:567-572, 1988
    • (1988) Blood , vol.72 , pp. 567-572
    • Huang, M.E.1    Ye, Y.C.2    Chen, S.R.3
  • 133
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • Druker BJ, Sawyers CL, Kantarjian H, et al: Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 344:1038-1042, 2001
    • (2001) N Engl J Med , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3
  • 134
    • 0035051044 scopus 로고    scopus 로고
    • Sensitivity to the abl inhibitor STI571 in fresh leukaemic cells obtained from chronic myelogenous leukaemia patients in different stages of disease
    • Gambacorti-Passerini C, Barni R, Marches: E, et al: Sensitivity to the abl inhibitor STI571 in fresh leukaemic cells obtained from chronic myelogenous leukaemia patients in different stages of disease. Br J Haematol 112:972-974, 2001
    • (2001) Br J Haematol , vol.112 , pp. 972-974
    • Gambacorti-Passerini, C.1    Barni, R.2    Marches, E.3
  • 135
    • 0034254368 scopus 로고    scopus 로고
    • Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: Diverse mechanisms of resistance
    • Mahon FX, Deininger MW, Schultheis B, et al: Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: Diverse mechanisms of resistance. Blood 96:1070-1079, 2000
    • (2000) Blood , vol.96 , pp. 1070-1079
    • Mahon, F.X.1    Deininger, M.W.2    Schultheis, B.3
  • 137
    • 13344295088 scopus 로고    scopus 로고
    • Mechanisms of retinoid resistance in leukemic cells: Possible role of cytochrome P450 and P-glycoprotein
    • Kizaki M, Ueno H, Yamazoe Y, et al: Mechanisms of retinoid resistance in leukemic cells: Possible role of cytochrome P450 and P-glycoprotein. Blood 87:725-733, 1996
    • (1996) Blood , vol.87 , pp. 725-733
    • Kizaki, M.1    Ueno, H.2    Yamazoe, Y.3
  • 138
    • 0035726732 scopus 로고    scopus 로고
    • Alteration of drug biotransformation and elimination during infection and inflammation
    • Renton KW: Alteration of drug biotransformation and elimination during infection and inflammation. Pharmacol Ther 92:147-163, 2001
    • (2001) Pharmacol Ther , vol.92 , pp. 147-163
    • Renton, K.W.1
  • 139
    • 0035119064 scopus 로고    scopus 로고
    • Regulation of cytochrome p450 by inflammatory mediators: Why and how?
    • Morgan ET: Regulation of cytochrome p450 by inflammatory mediators: Why and how? Drug Metab Dispos 29:207-212, 2001
    • (2001) Drug Metab Dispos , vol.29 , pp. 207-212
    • Morgan, E.T.1
  • 140
    • 0242684607 scopus 로고    scopus 로고
    • Inflammatory response: An unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy
    • Slaviero KA, Clarke SJ, Rivory LP: Inflammatory response: An unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy. Lancet Oncol 4:224-232, 2003
    • (2003) Lancet Oncol , vol.4 , pp. 224-232
    • Slaviero, K.A.1    Clarke, S.J.2    Rivory, L.P.3
  • 141
    • 0021929410 scopus 로고
    • Effects of influenza virus vaccine on hepatic drug metabolism
    • Meredith CG, Christian CD, Johnson RE, et al: Effects of influenza virus vaccine on hepatic drug metabolism. Clin Pharmacol Ther 37:396-401, 1985
    • (1985) Clin Pharmacol Ther , vol.37 , pp. 396-401
    • Meredith, C.G.1    Christian, C.D.2    Johnson, R.E.3
  • 142
    • 0022412140 scopus 로고
    • Hepatic drug-metabolising enzymes in lung tumour-bearing rats
    • Dogra SC, Khanduja KL, Sharma RR: Hepatic drug-metabolising enzymes in lung tumour-bearing rats. Biochem Pharmacol 34:3190-3193, 1985
    • (1985) Biochem Pharmacol , vol.34 , pp. 3190-3193
    • Dogra, S.C.1    Khanduja, K.L.2    Sharma, R.R.3
  • 143
    • 2442628298 scopus 로고    scopus 로고
    • Biochemical characterisation of in vivo alkylating agent resistance of a murine EMT-6 mammary carcinoma
    • Chen G, Teicher BA, Frei E: Biochemical characterisation of in vivo alkylating agent resistance of a murine EMT-6 mammary carcinoma. Cancer Biochem Biophys 16:139-155, 1998
    • (1998) Cancer Biochem Biophys , vol.16 , pp. 139-155
    • Chen, G.1    Teicher, B.A.2    Frei, E.3
  • 144
    • 0036380397 scopus 로고    scopus 로고
    • Decreased hepatic drug metabolising enzyme activity in rats with nitrosamine-induced tumours
    • Maliakal PP, Colville PF, Wanwimolruk S: Decreased hepatic drug metabolising enzyme activity in rats with nitrosamine-induced tumours. Drug Metabol Drug Interact 19:13-27, 2002
    • (2002) Drug Metabol Drug Interact , vol.19 , pp. 13-27
    • Maliakal, P.P.1    Colville, P.F.2    Wanwimolruk, S.3
  • 145
    • 0035038677 scopus 로고    scopus 로고
    • Cytokines influence mRNA expression of cytochrome P450 3A4 and MDRI in intestinal cells
    • Bertilsson PM, Olsson P, Magnusson KE: Cytokines influence mRNA expression of cytochrome P450 3A4 and MDRI in intestinal cells. J Pharm Sci 90:638-646, 2001
    • (2001) J Pharm Sci , vol.90 , pp. 638-646
    • Bertilsson, P.M.1    Olsson, P.2    Magnusson, K.E.3
  • 146
    • 0028342462 scopus 로고
    • Expression of xenobiotic-metabolising enzymes by primary and secondary tumors in man
    • Philip PA, Kaklamanis L, Ryley N, et al: Expression of xenobiotic-metabolising enzymes by primary and secondary tumors in man. Int J Radiat Oncol Biol Phys 29:277-283, 1994
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , pp. 277-283
    • Philip, P.A.1    Kaklamanis, L.2    Ryley, N.3
  • 147
    • 0037194409 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response
    • Rivory LP, Slaviero KA, Clarke SJ: Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response. Br J Cancer 87:277-280, 2002
    • (2002) Br J Cancer , vol.87 , pp. 277-280
    • Rivory, L.P.1    Slaviero, K.A.2    Clarke, S.J.3
  • 148
    • 0025214234 scopus 로고
    • Identification of the human liver cytochrome P450 responsible for coumarin 7-hydroxylase activity
    • Miles JS, Mclaren AW, Forrester LM, et al: Identification of the human liver cytochrome P450 responsible for coumarin 7-hydroxylase activity. Biochem J 267:365-371, 1990
    • (1990) Biochem J , vol.267 , pp. 365-371
    • Miles, J.S.1    Mclaren, A.W.2    Forrester, L.M.3
  • 149
    • 0025249973 scopus 로고
    • The maintenance of cytochrome P-450 in rat hepatocyte culture: Some applications of liver cell cultures in the study of drug metabolism, toxicity and induction of the P-450 system
    • Paine AJ: The maintenance of cytochrome P-450 in rat hepatocyte culture: Some applications of liver cell cultures in the study of drug metabolism, toxicity and induction of the P-450 system. Chem Biol Interact 74:1-31, 1990
    • (1990) Chem Biol Interact , vol.74 , pp. 1-31
    • Paine, A.J.1
  • 150
    • 0025006860 scopus 로고
    • High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
    • Antequara F, Boyes J, Bird A: High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell 6:503-514, 1990
    • (1990) Cell , vol.6 , pp. 503-514
    • Antequara, F.1    Boyes, J.2    Bird, A.3
  • 151
    • 0036301269 scopus 로고    scopus 로고
    • Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: Molecular mechanisms that determine lower expression in cultured cells
    • Rodriguez-Anotna C, Donato MT, Boobis A, et al: Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: Molecular mechanisms that determine lower expression in cultured cells. Xenobiotica 32:505-520, 2002
    • (2002) Xenobiotica , vol.32 , pp. 505-520
    • Rodriguez-Anotna, C.1    Donato, M.T.2    Boobis, A.3
  • 152
    • 0028899786 scopus 로고
    • Structural requirements for interaction with the oligopeptide transporter in Caco-2 cells
    • Hidalgo IJ, Bhatnagar P, Lee CP, et al: Structural requirements for interaction with the oligopeptide transporter in Caco-2 cells. Pharm Res 12:317-319, 1995
    • (1995) Pharm Res , vol.12 , pp. 317-319
    • Hidalgo, I.J.1    Bhatnagar, P.2    Lee, C.P.3
  • 153
    • 0035111995 scopus 로고    scopus 로고
    • P450 enzyme expression patterns in the NCI human tumor cell line panel
    • Yu LJ, Matias J, Scudiero DA, et al: P450 enzyme expression patterns in the NCI human tumor cell line panel. Drug Metab Dispos 29:304-312, 2001
    • (2001) Drug Metab Dispos , vol.29 , pp. 304-312
    • Yu, L.J.1    Matias, J.2    Scudiero, D.A.3
  • 154
    • 0026793052 scopus 로고
    • Purification and characterization of dihydropyrimidine dehydrogenase from human liver
    • Lu ZH, Zhang R, Diasio RB: Purification and characterization of dihydropyrimidine dehydrogenase from human liver. J Biol Chem 267:17102-17109, 1992
    • (1992) J Biol Chem , vol.267 , pp. 17102-17109
    • Lu, Z.H.1    Zhang, R.2    Diasio, R.B.3
  • 155
    • 0028097137 scopus 로고
    • A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil
    • Beck A, Etienne MC, Cheradame S, et al: A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil. Eur J Cancer 30:1517-1522, 1994
    • (1994) Eur J Cancer , vol.30 , pp. 1517-1522
    • Beck, A.1    Etienne, M.C.2    Cheradame, S.3
  • 156
    • 0032438744 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer
    • Nita ME, Tominaga O, Nagawa H, et al: Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer. Hepatogastroenterology 45:2117-2122, 1998
    • (1998) Hepatogastroenterology , vol.45 , pp. 2117-2122
    • Nita, M.E.1    Tominaga, O.2    Nagawa, H.3
  • 157
    • 0028982820 scopus 로고
    • Response to fluorouracil therapy in cancer patients: The role of tumoral dihydropyrimidine dehydrogenase activity
    • Etienne MC, Cheradame S, Fischel JL, et al: Response to fluorouracil therapy in cancer patients: The role of tumoral dihydropyrimidine dehydrogenase activity. J Clin Oncol 13:1663-1670, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 1663-1670
    • Etienne, M.C.1    Cheradame, S.2    Fischel, J.L.3
  • 158
    • 0003339957 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase and thymidylate synthase gene expressions identify a high percentage of colorectal tumors responding to 5-fluorouracil
    • abstr 992
    • Danenberg K, Salonga D, Park CG, et al: Dihydropyrimidine dehydrogenase and thymidylate synthase gene expressions identify a high percentage of colorectal tumors responding to 5-fluorouracil. Proc Am Soc Clin Oncol 17:258a, 1998 (abstr 992)
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Danenberg, K.1    Salonga, D.2    Park, C.G.3
  • 159
    • 0034012706 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: Possible predictor for sensitivity to 5-fluorouracil
    • Ishikawa Y, Kubota T, Otani Y, et al: Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: Possible predictor for sensitivity to 5-fluorouracil. Jpn J Cancer Res 91:105-112, 2000
    • (2000) Jpn J Cancer Res , vol.91 , pp. 105-112
    • Ishikawa, Y.1    Kubota, T.2    Otani, Y.3
  • 160
    • 0034048729 scopus 로고    scopus 로고
    • Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
    • Salonga D, Danenberg KD, Johnson M, et al: Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 6:1322-1327, 2000
    • (2000) Clin Cancer Res , vol.6 , pp. 1322-1327
    • Salonga, D.1    Danenberg, K.D.2    Johnson, M.3
  • 161
    • 0035289301 scopus 로고    scopus 로고
    • Determinants of prognosis and response to therapy in colorectal cancer
    • Iqbal S, Lenz H-J: Determinants of prognosis and response to therapy in colorectal cancer. Curr Oncol Rep 3:102-108, 2001
    • (2001) Curr Oncol Rep , vol.3 , pp. 102-108
    • Iqbal, S.1    Lenz, H.-J.2
  • 162
    • 0030051928 scopus 로고    scopus 로고
    • Metabolism of docetaxel by human cytochromes P450: Interactions with paclitaxel and other anti-neoplastic drugs
    • Royer I, Monsarrat B, Sonnier M, et al: Metabolism of docetaxel by human cytochromes P450: Interactions with paclitaxel and other anti-neoplastic drugs. Cancer Res 56:58-65, 1996
    • (1996) Cancer Res , vol.56 , pp. 58-65
    • Royer, I.1    Monsarrat, B.2    Sonnier, M.3
  • 163
    • 0036132097 scopus 로고    scopus 로고
    • Prediction of response to docetaxel by CYP3A4 mRNA expression in breast cancer tissues
    • Miyoshi Y, Ando A, Takamura Y, et al: Prediction of response to docetaxel by CYP3A4 mRNA expression in breast cancer tissues. Int J Cancer 97:129-132, 2002
    • (2002) Int J Cancer , vol.97 , pp. 129-132
    • Miyoshi, Y.1    Ando, A.2    Takamura, Y.3
  • 164
    • 0030863434 scopus 로고    scopus 로고
    • Bioactivation of the anticancer agent CPT-11 to SN-38 by human hepatic microsomal carboxylesterases and the in vitro assessment of potential drug interactions
    • Slatter JG, Su P, Sams JP, et al: Bioactivation of the anticancer agent CPT-11 to SN-38 by human hepatic microsomal carboxylesterases and the in vitro assessment of potential drug interactions. Drug Metab Dispos 25:1157-1164, 1997
    • (1997) Drug Metab Dispos , vol.25 , pp. 1157-1164
    • Slatter, J.G.1    Su, P.2    Sams, J.P.3
  • 165
    • 0032519431 scopus 로고    scopus 로고
    • Genetic predisposition to the metabolism of irinotecan (CPT-11): Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
    • Iyer L, King CD, Whitington PF, et al: Genetic predisposition to the metabolism of irinotecan (CPT-11): Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J Clin Invest 101:847-854, 1998
    • (1998) J Clin Invest , vol.101 , pp. 847-854
    • Iyer, L.1    King, C.D.2    Whitington, P.F.3
  • 166
    • 0032585232 scopus 로고    scopus 로고
    • Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer
    • Cunningham D, Pyrhonen S, James RD, et al: Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet 352:1413-1418, 1998
    • (1998) Lancet , vol.352 , pp. 1413-1418
    • Cunningham, D.1    Pyrhonen, S.2    James, R.D.3
  • 167
    • 0034727063 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer: Irinotecan Study Group
    • Saltz LB, Cox JV, Blanke C, et al: Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer: Irinotecan Study Group. N Engl J Med 343:905-914, 2000
    • (2000) N Engl J Med , vol.343 , pp. 905-914
    • Saltz, L.B.1    Cox, J.V.2    Blanke, C.3
  • 168
    • 0037050354 scopus 로고    scopus 로고
    • Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer
    • Noda K, Nishiwaki Y, Kawahara M, et al: Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer. N Engl J Med 346:85-91, 2002
    • (2002) N Engl J Med , vol.346 , pp. 85-91
    • Noda, K.1    Nishiwaki, Y.2    Kawahara, M.3
  • 169
    • 0036924112 scopus 로고    scopus 로고
    • Irinotecan: Mechanisms of tumor resistance and novel strategies for modulating its activity
    • Xu Y, Villalona-Calero MA: Irinotecan: Mechanisms of tumor resistance and novel strategies for modulating its activity. Ann Oncol 13:1841-1851, 2002
    • (2002) Ann Oncol , vol.13 , pp. 1841-1851
    • Xu, Y.1    Villalona-Calero, M.A.2
  • 170
    • 2442449490 scopus 로고    scopus 로고
    • Cellular parameters predictive of the clinical response of colorectal cancers to irinotecan: A preliminary study
    • Pavillard V, Charasson V, Laroche-Clary A, et al: Cellular parameters predictive of the clinical response of colorectal cancers to irinotecan: A preliminary study. Anticancer Res 24:579-585, 2004
    • (2004) Anticancer Res , vol.24 , pp. 579-585
    • Pavillard, V.1    Charasson, V.2    Laroche-Clary, A.3
  • 171
    • 2642521486 scopus 로고    scopus 로고
    • The relative contributions of carboxylesterase and beta-glucuronidase in the formation of SN-38 in human colorectal tumours
    • Tobin PJ, Dodds HM, Clarke S, et al: The relative contributions of carboxylesterase and beta-glucuronidase in the formation of SN-38 in human colorectal tumours. Oncol Rep 10:1977-1979, 2003
    • (2003) Oncol Rep , vol.10 , pp. 1977-1979
    • Tobin, P.J.1    Dodds, H.M.2    Clarke, S.3
  • 172
    • 0036023423 scopus 로고    scopus 로고
    • Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan
    • Xu G, Zhang W, Ma MK, et al: Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan. Clin Cancer Res 8:2605-2611, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 2605-2611
    • Xu, G.1    Zhang, W.2    Ma, M.K.3
  • 173
    • 0031800370 scopus 로고    scopus 로고
    • Determinants of CPT-11 and SN-38 activities in human lung cancer cells
    • van Ark-Otte J, Kedde MA, van der Vijgh WJ, et al: Determinants of CPT-11 and SN-38 activities in human lung cancer cells. Br J Cancer 77:2171-2176, 1998
    • (1998) Br J Cancer , vol.77 , pp. 2171-2176
    • Van Ark-Otte, J.1    Kedde, M.A.2    Van Der Vijgh, W.J.3
  • 174
    • 0036023452 scopus 로고    scopus 로고
    • Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells
    • Wu MH, Yan B, Humerickhouse R, et al: Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells. Clin Cancer Res 8:2696-2700, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 2696-2700
    • Wu, M.H.1    Yan, B.2    Humerickhouse, R.3
  • 175
    • 0345734082 scopus 로고    scopus 로고
    • Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: Reversal of resistance by food additives
    • Cummings J, Ethell BT, Jardine L, et al: Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: Reversal of resistance by food additives. Cancer Res 63:8443-8450, 2003
    • (2003) Cancer Res , vol.63 , pp. 8443-8450
    • Cummings, J.1    Ethell, B.T.2    Jardine, L.3
  • 176
    • 0031473370 scopus 로고    scopus 로고
    • The role of glucuronidation in 7-ethyl-10-hydroxycamptothecin resistance in vitro
    • Takahashi T, Fujiwara Y, Yamakido M, et al: The role of glucuronidation in 7-ethyl-10-hydroxycamptothecin resistance in vitro. Jpn J Cancer Res 88:1211-1217, 1997
    • (1997) Jpn J Cancer Res , vol.88 , pp. 1211-1217
    • Takahashi, T.1    Fujiwara, Y.2    Yamakido, M.3
  • 177
    • 0037085032 scopus 로고    scopus 로고
    • Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation
    • Cummings J, Boyd G, Ethell BT, et al: Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation. Biochem Pharmacol 63:607-613, 2002
    • (2002) Biochem Pharmacol , vol.63 , pp. 607-613
    • Cummings, J.1    Boyd, G.2    Ethell, B.T.3
  • 178
    • 0345549402 scopus 로고    scopus 로고
    • Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: Contribution of drug transport proteins
    • Cummings J, Zelcer N, Allen JD, et al: Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: Contribution of drug transport proteins. Biochem Pharmacol 67:31-39, 2004
    • (2004) Biochem Pharmacol , vol.67 , pp. 31-39
    • Cummings, J.1    Zelcer, N.2    Allen, J.D.3
  • 179
    • 0032873333 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines
    • Sladek NE: Aldehyde dehydrogenase-mediated cellular relative
    • (1999) Curr Pharm des , vol.5 , pp. 607-625
    • Sladek, N.E.1
  • 180
    • 0037134707 scopus 로고    scopus 로고
    • Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer
    • Stoehlmacher J, Park DJ, Zhang W, et al: Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J Natl Cancer Inst 94:936-942, 2002
    • (2002) J Natl Cancer Inst , vol.94 , pp. 936-942
    • Stoehlmacher, J.1    Park, D.J.2    Zhang, W.3
  • 181
    • 0034651551 scopus 로고    scopus 로고
    • Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: A case-control study
    • Stanulla M, Schrappe M, Brechlin AM, et al: Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: A case-control study. Blood 95:1222-1228, 2000
    • (2000) Blood , vol.95 , pp. 1222-1228
    • Stanulla, M.1    Schrappe, M.2    Brechlin, A.M.3
  • 182
    • 0036304753 scopus 로고    scopus 로고
    • Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes, DNA repair enzymes, and response to treatment of childhood acute lymphoblastic leukemia
    • Krajinovic M, Labuda D, Mathonnet G, et al: Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes, DNA repair enzymes, and response to treatment of childhood acute lymphoblastic leukemia. Clin Cancer Res 8:802-810, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 802-810
    • Krajinovic, M.1    Labuda, D.2    Mathonnet, G.3
  • 183
    • 0037350198 scopus 로고    scopus 로고
    • Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment
    • Sweeney C, Ambrosone CB, Joseph L, et al: Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment. Int J Cancer 103:810-814, 2003
    • (2003) Int J Cancer , vol.103 , pp. 810-814
    • Sweeney, C.1    Ambrosone, C.B.2    Joseph, L.3
  • 184
    • 0033386787 scopus 로고    scopus 로고
    • Significance of multidrug-resistant proteins in predicting chemotherapy response and prognosis in epithelial ovarian cancer
    • Yokoyama Y, Sato S, Fukushi Y, et al: Significance of multidrug-resistant proteins in predicting chemotherapy response and prognosis in epithelial ovarian cancer. J Obstet Gynaecol Res 25:387-394, 1999
    • (1999) J Obstet Gynaecol Res , vol.25 , pp. 387-394
    • Yokoyama, Y.1    Sato, S.2    Fukushi, Y.3
  • 185
    • 0033841414 scopus 로고    scopus 로고
    • Immunohistochemical expression of glutathione transferase-pi in untreated primary non-small cell lung cancer
    • Arai T, Yasuda Y, Takaya T, et al: Immunohistochemical expression of glutathione transferase-pi in untreated primary non-small cell lung cancer. Cancer Detect Prev 24:252-257, 2000
    • (2000) Cancer Detect Prev , vol.24 , pp. 252-257
    • Arai, T.1    Yasuda, Y.2    Takaya, T.3
  • 186
    • 0032562526 scopus 로고    scopus 로고
    • Association between expression of glutathione-associated enzymes and response to platinum-based chemotherapy in head and neck cancer
    • Nishimura T, Newkirk K, Sessions RB, et al: Association between expression of glutathione-associated enzymes and response to platinum-based chemotherapy in head and neck cancer. Chem Biol Interact 111-112:187-198, 1998
    • (1998) Chem Biol Interact , vol.111-112 , pp. 187-198
    • Nishimura, T.1    Newkirk, K.2    Sessions, R.B.3
  • 187
    • 0030843282 scopus 로고    scopus 로고
    • Prognostic significance of the expression of metallothionein, glutathione-S-transferase-pi, and P-glycoprotein in curatively resected gastric cancer
    • Monden N, Abe S, Sutoh I, et al: Prognostic significance of the expression of metallothionein, glutathione-S-transferase-pi, and P-glycoprotein in curatively resected gastric cancer. Oncology 54:391-399, 1997
    • (1997) Oncology , vol.54 , pp. 391-399
    • Monden, N.1    Abe, S.2    Sutoh, I.3
  • 188
    • 0025303623 scopus 로고
    • Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients
    • Schisselbauer JC, Silber R, Papadopoulos E, et al: Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients. Cancer Res 50:3562-3568, 1990
    • (1990) Cancer Res , vol.50 , pp. 3562-3568
    • Schisselbauer, J.C.1    Silber, R.2    Papadopoulos, E.3
  • 189
    • 0026725084 scopus 로고
    • Expression of glutathione transferase π as a predictor for treatment results at different stages of acute non-lymphoblastic leukemia
    • Tidefelt U, Elmhorn-Rosenborg A, Paul C, et al: Expression of glutathione transferase π as a predictor for treatment results at different stages of acute non-lymphoblastic leukemia. Cancer Res 52:3281-3285, 1992
    • (1992) Cancer Res , vol.52 , pp. 3281-3285
    • Tidefelt, U.1    Elmhorn-Rosenborg, A.2    Paul, C.3
  • 190
    • 0030037901 scopus 로고    scopus 로고
    • The relationship between tumour glutathione concentration, glutathione S-transferase isoenzyme expression and response to single agent carboplatin in epithelial ovarian cancer patients
    • Ghazal-Aswad S, Hogarth L, Hall AG, et al: The relationship between tumour glutathione concentration, glutathione S-transferase isoenzyme expression and response to single agent carboplatin in epithelial ovarian cancer patients. Br J Cancer 74:468-473, 1996
    • (1996) Br J Cancer , vol.74 , pp. 468-473
    • Ghazal-Aswad, S.1    Hogarth, L.2    Hall, A.G.3
  • 191
    • 0038692917 scopus 로고    scopus 로고
    • Glutathione-S transferase expression in non-small cell lung cancer in the assessment of response to chemotherapy
    • Unsal M, Akpolat I, Kandemir B: Glutathione-S transferase expression in non-small cell lung cancer in the assessment of response to chemotherapy. Saudi Med 24:493-498, 2003
    • (2003) Saudi Med , vol.24 , pp. 493-498
    • Unsal, M.1    Akpolat, I.2    Kandemir, B.3
  • 192
    • 0031009242 scopus 로고    scopus 로고
    • Glutathione S-transferase activity in epithelial ovarian cancer: Association with response to chemotherapy and disease outcome
    • Ferrandina G, Scambia G, Damia G, et al: Glutathione S-transferase activity in epithelial ovarian cancer: Association with response to chemotherapy and disease outcome. Ann Oncol 8:342-350, 1997
    • (1997) Ann Oncol , vol.8 , pp. 342-350
    • Ferrandina, G.1    Scambia, G.2    Damia, G.3
  • 193
    • 0038352146 scopus 로고    scopus 로고
    • Cytochrome P450 CYP3A4/5 expression as a biomarker of outcome in osteosarcoma
    • Dhaini HR, Thomas DG, Giordano TJ, et al: Cytochrome P450 CYP3A4/5 expression as a biomarker of outcome in osteosarcoma. J Clin Oncol 21:2481-2485, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 2481-2485
    • Dhaini, H.R.1    Thomas, D.G.2    Giordano, T.J.3
  • 194
    • 0035503151 scopus 로고    scopus 로고
    • Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
    • Van Cutsem E, Twelves C, Cassidy J, et al: Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study. J Clin Oncol 19:4097-4106, 2001
    • (2001) J Clin Oncol , vol.19 , pp. 4097-4106
    • Van Cutsem, E.1    Twelves, C.2    Cassidy, J.3
  • 195
    • 0035871538 scopus 로고    scopus 로고
    • Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer
    • Hoff PM, Anasari R, Batist G, et al: Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer. J Clin Oncol 19:2282-2292, 2001
    • (2001) J Clin Oncol , vol.19 , pp. 2282-2292
    • Hoff, P.M.1    Anasari, R.2    Batist, G.3
  • 196
    • 4444377696 scopus 로고    scopus 로고
    • Capecitabine vs 5FU/leucovorin as adjuvant therapy for colon cancer (the X-ACT study): Efficacy of a phase III trial
    • abstr 3509
    • Cassidy J, Scheithauer W, McKendrick J, et al: Capecitabine vs 5FU/leucovorin as adjuvant therapy for colon cancer (the X-ACT study): Efficacy of a phase III trial. Proc Amer Soc Clin Oncol 23:247s, 2004 (abstr 3509)
    • (2004) Proc Amer Soc Clin Oncol , vol.23
    • Cassidy, J.1    Scheithauer, W.2    McKendrick, J.3
  • 197
    • 0031859855 scopus 로고    scopus 로고
    • Preliminary studies of a novel oral fluoropyrimidine carbamate: Capecitabine
    • Budman DR, Meropol NJ, Reigner B, et al: Preliminary studies of a novel oral fluoropyrimidine carbamate: Capecitabine. J Clin Oncol 16:1795-1802, 1998
    • (1998) J Clin Oncol , vol.16 , pp. 1795-1802
    • Budman, D.R.1    Meropol, N.J.2    Reigner, B.3
  • 198
    • 0034745284 scopus 로고    scopus 로고
    • Capecitabine (Xeloda) improves medical resource use compared with 5-fluorouracil plus leucovorin in a phase III trial conducted in patients with advanced colorectal cancer
    • Twelves C, Boyer M, Findlay M, et al: Capecitabine (Xeloda) improves medical resource use compared with 5-fluorouracil plus leucovorin in a phase III trial conducted in patients with advanced colorectal cancer. Eur J Cancer 37:597-604, 2001
    • (2001) Eur J Cancer , vol.37 , pp. 597-604
    • Twelves, C.1    Boyer, M.2    Findlay, M.3
  • 199
    • 9144238357 scopus 로고    scopus 로고
    • Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: Safety results of a randomized phase III trial
    • Scheithauer W, McKendrick J, Begbie S, et al: Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: Safety results of a randomized phase III trial. Ann Oncol 14:1735-1743, 2003
    • (2003) Ann Oncol , vol.14 , pp. 1735-1743
    • Scheithauer, W.1    McKendrick, J.2    Begbie, S.3
  • 200
    • 0035289240 scopus 로고    scopus 로고
    • Current status of oral chemotherapy for colorectal cancer
    • Diasio RB: Current status of oral chemotherapy for colorectal cancer. Oncology (Huntingt) 15:16-20, 2001 (3 Suppl 5)
    • (2001) Oncology (Huntingt) , vol.15 , Issue.3 SUPPL. 5 , pp. 16-20
    • Diasio, R.B.1
  • 201
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio RB, Harris BE: Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet 16:215-237, 1989
    • (1989) Clin Pharmacokinet , vol.16 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 202
    • 0033056070 scopus 로고    scopus 로고
    • A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil
    • Etienne MC, Pivot X, Formento JL, et al: A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil. Br J Cancer 79:1864-1869, 1999
    • (1999) Br J Cancer , vol.79 , pp. 1864-1869
    • Etienne, M.C.1    Pivot, X.2    Formento, J.L.3
  • 203
    • 10544243363 scopus 로고    scopus 로고
    • Pharmacokinetic, oral bioavailability, and safety study of fluorouracil in patients treated with 776C85, an inactivator of dihydropyrimidine dehydrogenase
    • Baker SD, Peang Khor S, Adjei AA, et al: Pharmacokinetic, oral bioavailability, and safety study of fluorouracil in patients treated with 776C85, an inactivator of dihydropyrimidine dehydrogenase. J Clin Oncol 14:3085-3096, 1996
    • (1996) J Clin Oncol , vol.14 , pp. 3085-3096
    • Baker, S.D.1    Peang Khor, S.2    Adjei, A.A.3
  • 204
    • 0037087668 scopus 로고    scopus 로고
    • Randomized, open-label, phase III study of a 28-day oral regimen of eniluracil plus fluorouracil versus intravenous fluorouracil plus leucovorin as first-line therapy in patients with metastatic/advanced colorectal cancer
    • Schilsky RL, Levin J, West WH, et al: Randomized, open-label, phase III study of a 28-day oral regimen of eniluracil plus fluorouracil versus intravenous fluorouracil plus leucovorin as first-line therapy in patients with metastatic/advanced colorectal cancer. J Clin Oncol 15:1519-1526, 2002
    • (2002) J Clin Oncol , vol.15 , pp. 1519-1526
    • Schilsky, R.L.1    Levin, J.2    West, W.H.3
  • 205
    • 0003300519 scopus 로고    scopus 로고
    • International phase III study of oral eniluracil plus 5-fluorouracil versus intravenous (IV) 5-FU plus leucovorin (LV) in the treatment of advanced colorectal cancer
    • abstr 522
    • Van Cutsem E, Sorensen J, Cassidy J, et al: International phase III study of oral eniluracil plus 5-fluorouracil versus intravenous (IV) 5-FU plus leucovorin (LV) in the treatment of advanced colorectal cancer. Proc Am Soc Clin Oncol 20:131a, 2001 (abstr 522)
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Van Cutsem, E.1    Sorensen, J.2    Cassidy, J.3
  • 206
    • 0034089123 scopus 로고    scopus 로고
    • Phase II study of S-1, a novel oral fluoropyrimidine derivative in patients with metastatic colorectal carcinoma: S-1 Cooperative Colorectal Carcinoma Study Group
    • Ohtsu A, Baba H, Sakata Y, et al: Phase II study of S-1, a novel oral fluoropyrimidine derivative in patients with metastatic colorectal carcinoma: S-1 Cooperative Colorectal Carcinoma Study Group. Br J Cancer 83:141-145, 2000
    • (2000) Br J Cancer , vol.83 , pp. 141-145
    • Ohtsu, A.1    Baba, H.2    Sakata, Y.3
  • 207
    • 2442674385 scopus 로고    scopus 로고
    • Phase II study of S-1 for treatment of metastatic colorectal carcinoma
    • Shirao K, Ohtsu A, Takada H, et al: Phase II study of S-1 for treatment of metastatic colorectal carcinoma. Cancer 100:2355-2361, 2004
    • (2004) Cancer , vol.100 , pp. 2355-2361
    • Shirao, K.1    Ohtsu, A.2    Takada, H.3
  • 208
    • 0028356487 scopus 로고
    • Glutathione-S-transferase activates novel alkylating agents
    • Lyttle MH, Satyam A, Hocker MD, et al: Glutathione-S-transferase activates novel alkylating agents. J Med Chem 37:1501-1507, 1994
    • (1994) J Med Chem , vol.37 , pp. 1501-1507
    • Lyttle, M.H.1    Satyam, A.2    Hocker, M.D.3
  • 209
    • 17544385571 scopus 로고    scopus 로고
    • Tumor efficacy and bone marrow-sparing properties of TER286, a cytotoxin activated by glutathione S-transferase
    • Morgan AS, Sanderson PE, Borch RF, et al: Tumor efficacy and bone marrow-sparing properties of TER286, a cytotoxin activated by glutathione S-transferase. Cancer Res 58:2568-2575, 1998
    • (1998) Cancer Res , vol.58 , pp. 2568-2575
    • Morgan, A.S.1    Sanderson, P.E.2    Borch, R.F.3
  • 210
    • 0038523826 scopus 로고    scopus 로고
    • Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione analogue) in advanced refractory solid malignancies
    • Rosen LS, Brown J, Laxa B, et al: Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione analogue) in advanced refractory solid malignancies. Clin Cancer Res 9:1628-1638, 2003
    • (2003) Clin Cancer Res , vol.9 , pp. 1628-1638
    • Rosen, L.S.1    Brown, J.2    Laxa, B.3
  • 211
    • 18844442948 scopus 로고    scopus 로고
    • Phase I-2a dose ranging study of TLK286 (a novel glutathione analog) in combination with liposomal doxorubicin in platinum refractory or resistant ovarian cancer
    • abstr 5062
    • Brown GL, Lewis L, Choi H, et al: Phase I-2a dose ranging study of TLK286 (a novel glutathione analog) in combination with liposomal doxorubicin in platinum refractory or resistant ovarian cancer. Proc Am Soc Clin Oncol 23:464s, 2004 (abstr 5062)
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Brown, G.L.1    Lewis, L.2    Choi, H.3
  • 213
    • 84871467742 scopus 로고    scopus 로고
    • Phase I-2a dose ranging study of TLK286 (a novel glutathione analog) in combination with docetaxel in platinum-resistant non-small cell lung cancer
    • abstr 7140
    • Papadimitrakopoulou V, Boasberg P, Figlin R, et al: Phase I-2a dose ranging study of TLK286 (a novel glutathione analog) in combination with docetaxel in platinum-resistant non-small cell lung cancer. Proc Am Soc Clin Oncol 23:651s, 2004 (abstr 7140)
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Papadimitrakopoulou, V.1    Boasberg, P.2    Figlin, R.3
  • 214
    • 0035181464 scopus 로고    scopus 로고
    • Strategies for enzyme/prodrug cancer therapy
    • Xu G, McLeod HL: Strategies for enzyme/prodrug cancer therapy. Clin Cancer Res 7:3314-3324, 2001
    • (2001) Clin Cancer Res , vol.7 , pp. 3314-3324
    • Xu, G.1    McLeod, H.L.2
  • 215
    • 0032797555 scopus 로고    scopus 로고
    • Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase
    • Evrard A, Cuq P, Ciccolini J, et al: Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase. Br J Cancer 80:1726-1733, 1999
    • (1999) Br J Cancer , vol.80 , pp. 1726-1733
    • Evrard, A.1    Cuq, P.2    Ciccolini, J.3
  • 216
    • 0032929154 scopus 로고    scopus 로고
    • Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme/prodrug therapy
    • Danks MK, Morton CL, Krull EJ, et al: Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme/prodrug therapy. Clin Cancer Res 5:917-924, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 917-924
    • Danks, M.K.1    Morton, C.L.2    Krull, E.J.3
  • 217
    • 0036244747 scopus 로고    scopus 로고
    • Microencapsulated, CYP2B1-transfected cells activating ifosfamide at the site of the tumor: The magic bullets of the 21st century
    • Lohr M, Hummel F, Faulmann G, et al: Microencapsulated, CYP2B1-transfected cells activating ifosfamide at the site of the tumor: The magic bullets of the 21st century. Cancer Chemother Pharmacol 49:S21-S24, 2002 (suppl 1)
    • (2002) Cancer Chemother Pharmacol , vol.49 , Issue.SUPPL. 1
    • Lohr, M.1    Hummel, F.2    Faulmann, G.3
  • 218
    • 84871471652 scopus 로고    scopus 로고
    • Phase I study of MetXia-450 therapy in patients with advanced breast cancer or melanoma
    • abstr 84
    • Braybrooke JP, Slade A, Gibson R, et al: Phase I study of MetXia-450 therapy in patients with advanced breast cancer or melanoma. Proc Am Soc Clin Oncol 21:22a, 2002 (abstr 84)
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Braybrooke, J.P.1    Slade, A.2    Gibson, R.3
  • 219
    • 2442696806 scopus 로고    scopus 로고
    • Virus-directed enzyme prodrug therapy: Intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer
    • Palmer DH, Mautner V, Mirza D, et al: Virus-directed enzyme prodrug therapy: Intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer. J Clin Oncol 22:1546-1552, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 1546-1552
    • Palmer, D.H.1    Mautner, V.2    Mirza, D.3
  • 220
    • 85026307286 scopus 로고    scopus 로고
    • A clinical trial of virus-directed enzyme prodrug therapy (VDEPT) using adenovirus encoded nitroreductase and CB1954 in patients with localized prostate cancer
    • abstr 4572
    • James ND, Patel P, Mautner V, et al: A clinical trial of virus-directed enzyme prodrug therapy (VDEPT) using adenovirus encoded nitroreductase and CB1954 in patients with localized prostate cancer. Proc Am Soc Clin Oncol 23:399s, 2004 (abstr 4572)
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • James, N.D.1    Patel, P.2    Mautner, V.3
  • 221
    • 0033567097 scopus 로고    scopus 로고
    • Enhancement of antibody-directed enzyme pro-drug therapy in colorectal xenografts by an antivascular agent
    • Pedley RB, Sharma SK, Boxer GM, et al: Enhancement of antibody-directed enzyme pro-drug therapy in colorectal xenografts by an antivascular agent. Cancer Res 59:3998-4003, 1999
    • (1999) Cancer Res , vol.59 , pp. 3998-4003
    • Pedley, R.B.1    Sharma, S.K.2    Boxer, G.M.3
  • 222
    • 0033846834 scopus 로고    scopus 로고
    • Direct in vivo observation of 5-fluorouracil release from a prodrug in human tumors heterotransplanted in nude mice: A magnetic resonance study
    • Guerquin-Kern JL, Volk A, Chenu E, et al: Direct in vivo observation of 5-fluorouracil release from a prodrug in human tumors heterotransplanted in nude mice: A magnetic resonance study. NMR Biomed 13:306-310, 2000
    • (2000) NMR Biomed , vol.13 , pp. 306-310
    • Guerquin-Kern, J.L.1    Volk, A.2    Chenu, E.3
  • 223
    • 12944288238 scopus 로고    scopus 로고
    • Antibody-directed enzyme prodrug therapy: Efficacy and mechanism of action in colorectal carcinoma
    • Napier MP, Sharma SK, Springer CJ, et al: Antibody-directed enzyme prodrug therapy: Efficacy and mechanism of action in colorectal carcinoma. Clin Cancer Res 6:765-772, 2000
    • (2000) Clin Cancer Res , vol.6 , pp. 765-772
    • Napier, M.P.1    Sharma, S.K.2    Springer, C.J.3
  • 224
    • 0035875235 scopus 로고    scopus 로고
    • Measurement of the critical DNA lesions produced by antibody-directed enzyme prodrug therapy (ADEPT) in vitro, in vivo and in clinical material
    • Webley SD, Francis RJ, Pedley RB, et al: Measurement of the critical DNA lesions produced by antibody-directed enzyme prodrug therapy (ADEPT) in vitro, in vivo and in clinical material. Br J Cancer 84:1671-1676, 2001
    • (2001) Br J Cancer , vol.84 , pp. 1671-1676
    • Webley, S.D.1    Francis, R.J.2    Pedley, R.B.3
  • 226
    • 0032897384 scopus 로고    scopus 로고
    • Antibody directed enzyme prodrug therapy (ADEPT): A review of the experimental and clinical considerations
    • Syrigos KN, Epenetos AA: Antibody directed enzyme prodrug therapy (ADEPT): A review of the experimental and clinical considerations. Anticancer Res 19:605-613, 1999
    • (1999) Anticancer Res , vol.19 , pp. 605-613
    • Syrigos, K.N.1    Epenetos, A.A.2
  • 227
    • 0031944611 scopus 로고    scopus 로고
    • Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by taxol/taxotere in human cancer xenografts
    • Sawada N, Ishikawa T, Fukase Y, et al: Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by taxol/taxotere in human cancer xenografts. Clin Cancer Res 4:1013-1019, 1998
    • (1998) Clin Cancer Res , vol.4 , pp. 1013-1019
    • Sawada, N.1    Ishikawa, T.2    Fukase, Y.3
  • 228
    • 0034265883 scopus 로고    scopus 로고
    • Enhancement of immunohistochemical reactivity for thymidine phosphorylase in breast carcinoma cells after administration of docetaxel as a neoadjuvant chemotherapy in advanced breast cancer patients
    • Kurosumi M, Tabei T, Suemasu K, et al: Enhancement of immunohistochemical reactivity for thymidine phosphorylase in breast carcinoma cells after administration of docetaxel as a neoadjuvant chemotherapy in advanced breast cancer patients. Oncol Rep 7:945-948, 2000
    • (2000) Oncol Rep , vol.7 , pp. 945-948
    • Kurosumi, M.1    Tabei, T.2    Suemasu, K.3
  • 229
    • 0037096755 scopus 로고    scopus 로고
    • Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results
    • O'Shaughnessy J, Miles D, Vukelja S, et al: Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results. J Clin Oncol 20:2812-2823, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 2812-2823
    • O'Shaughnessy, J.1    Miles, D.2    Vukelja, S.3
  • 230
    • 0032695102 scopus 로고    scopus 로고
    • X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts
    • Sawada N, Ishikawa T, Sekiguchi F, et al: X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts. Clin Cancer Res 5:2948-2953, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 2948-2953
    • Sawada, N.1    Ishikawa, T.2    Sekiguchi, F.3
  • 231
    • 0003326684 scopus 로고    scopus 로고
    • Phase I study of capecitabine combined with radiotherapy for locally advanced potentially operable rectal cancer
    • abstr 591
    • Ngan S, Zalcberg J, Kell A, et al: Phase I study of capecitabine combined with radiotherapy for locally advanced potentially operable rectal cancer. Proc Am Soc Clin Oncol 20:149a, 2001 (abstr 591)
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Ngan, S.1    Zalcberg, J.2    Kell, A.3
  • 232
    • 0033636060 scopus 로고    scopus 로고
    • Regulation of dihydropyrimidine dehydrogenase and pyrimidine nucleoside phosphorylase activities by growth factors and subsequent effects on 5-fluorouracil sensitivity in tumor cells
    • Ueda M, Kitaura K, Kusada O, et al: Regulation of dihydropyrimidine dehydrogenase and pyrimidine nucleoside phosphorylase activities by growth factors and subsequent effects on 5-fluorouracil sensitivity in tumor cells. Jpn J Cancer Res 91:1185-1191, 2000
    • (2000) Jpn J Cancer Res , vol.91 , pp. 1185-1191
    • Ueda, M.1    Kitaura, K.2    Kusada, O.3
  • 233
    • 0031722179 scopus 로고    scopus 로고
    • High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil
    • Metzger R, Danenberg K, Leichman CG, et al: High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. Clin Cancer Res 4:2371-2376, 1998
    • (1998) Clin Cancer Res , vol.4 , pp. 2371-2376
    • Metzger, R.1    Danenberg, K.2    Leichman, C.G.3
  • 234
    • 0035105560 scopus 로고    scopus 로고
    • The results of colorectal cancer treatment by p53 status: Treatment-specific overview
    • Petersen S, Thames HD, Nieder C, et al: The results of colorectal cancer treatment by p53 status: Treatment-specific overview. Dis Colon Rectum 44:322-333, 2001
    • (2001) Dis Colon Rectum , vol.44 , pp. 322-333
    • Petersen, S.1    Thames, H.D.2    Nieder, C.3
  • 235
    • 0036534202 scopus 로고    scopus 로고
    • DNA microarrays in clinical oncology
    • Ramaswamy S, Golub TR: DNA microarrays in clinical oncology. J Clin Oncol 20:1932-1941, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 1932-1941
    • Ramaswamy, S.1    Golub, T.R.2
  • 238
    • 1342286839 scopus 로고    scopus 로고
    • Microdissection, mRNA amplification and microarray: A study of pleural mesothelial and malignant mesothelioma cells
    • Mohr S, Bottin MC, Lannes B, et al: Microdissection, mRNA amplification and microarray: A study of pleural mesothelial and malignant mesothelioma cells. Biochimie 86:13-19, 2004
    • (2004) Biochimie , vol.86 , pp. 13-19
    • Mohr, S.1    Bottin, M.C.2    Lannes, B.3
  • 239
    • 0037572309 scopus 로고    scopus 로고
    • Microarray analysis using amplified mRNA from laser capture microdissection of microscopic hepatocellular precancerous lesions and frozen hepatocellular carcinomas reveals unique and consistent gene expression profiles
    • Yim SH, Ward JM, Dragan Y, et al: Microarray analysis using amplified mRNA from laser capture microdissection of microscopic hepatocellular precancerous lesions and frozen hepatocellular carcinomas reveals unique and consistent gene expression profiles. Toxicol Pathol 31:295-303, 2003
    • (2003) Toxicol Pathol , vol.31 , pp. 295-303
    • Yim, S.H.1    Ward, J.M.2    Dragan, Y.3
  • 240
    • 0031879859 scopus 로고    scopus 로고
    • Identification of expressed genes by laser-mediated manipulation of single cells
    • Schutze K, Lahr G: Identification of expressed genes by laser-mediated manipulation of single cells. Nat Biotechnol 16:737-742, 1998
    • (1998) Nat Biotechnol , vol.16 , pp. 737-742
    • Schutze, K.1    Lahr, G.2
  • 241
    • 0142213544 scopus 로고    scopus 로고
    • Application of laser capture microdissection combined with two-dimensional electrophoresis for the discovery of differentially regulated proteins in pancreatic ductal adenocarcinoma
    • Shekouh AR, Thompson CC, Prime W, et al: Application of laser capture microdissection combined with two-dimensional electrophoresis for the discovery of differentially regulated proteins in pancreatic ductal adenocarcinoma. Proteomics 3:1988-2001, 2003
    • (2003) Proteomics , vol.3 , pp. 1988-2001
    • Shekouh, A.R.1    Thompson, C.C.2    Prime, W.3
  • 242
    • 0037099730 scopus 로고    scopus 로고
    • Microarrays as cancer keys: An array of possibilities
    • Mohr S, Leikauf GD, Keith G, et al: Microarrays as cancer keys: An array of possibilities. J Clin Oncol 20:3165-3175, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 3165-3175
    • Mohr, S.1    Leikauf, G.D.2    Keith, G.3
  • 243
    • 0033891762 scopus 로고    scopus 로고
    • Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray
    • Kudoh K, Ramanna M, Ravatn R, et al: Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray. Cancer Res 60:4161-4166, 2000
    • (2000) Cancer Res , vol.60 , pp. 4161-4166
    • Kudoh, K.1    Ramanna, M.2    Ravatn, R.3
  • 244
    • 84871472483 scopus 로고    scopus 로고
    • The use of CDNA microarray to identify paclitaxel-induced changes in gene expression in non-small cell lung carcinoma cell lines
    • abstr 1969
    • Volas-Redd GH, Than C, Neish A, et al: The use of CDNA microarray to identify paclitaxel-induced changes in gene expression in non-small cell lung carcinoma cell lines. Proc Am Clin Oncol 19:503a, 2000 (abstr 1969)
    • (2000) Proc Am Clin Oncol , vol.19
    • Volas-Redd, G.H.1    Than, C.2    Neish, A.3
  • 245
    • 1642576129 scopus 로고    scopus 로고
    • Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays
    • Kang HC, Kim IJ, Park JH, et al: Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays. Clin Cancer Res 10:272-284, 2004
    • (2004) Clin Cancer Res , vol.10 , pp. 272-284
    • Kang, H.C.1    Kim, I.J.2    Park, J.H.3
  • 246
    • 0036168343 scopus 로고    scopus 로고
    • An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines
    • Dan S, Tsunoda T, Kitahara O, et al: An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines. Cancer Res 62:1139-1147, 2002
    • (2002) Cancer Res , vol.62 , pp. 1139-1147
    • Dan, S.1    Tsunoda, T.2    Kitahara, O.3
  • 247
    • 0035802183 scopus 로고    scopus 로고
    • Prostasin, a potential serum marker for ovarian cancer: Identification through microarray technology
    • Mok SC, Chao J, Skates S, et al: Prostasin, a potential serum marker for ovarian cancer: Identification through microarray technology. Natl Cancer Inst 93:1458-1464, 2001
    • (2001) Natl Cancer Inst , vol.93 , pp. 1458-1464
    • Mok, S.C.1    Chao, J.2    Skates, S.3
  • 248
    • 0036735386 scopus 로고    scopus 로고
    • Translation of microarray data into clinically relevant cancer diagnostic tests using gene expression ratios in lung cancer and mesothelioma
    • Gordon GJ, Jensen RV, Hsiao LL, et al: Translation of microarray data into clinically relevant cancer diagnostic tests using gene expression ratios in lung cancer and mesothelioma. Cancer Res 62:4963-4967, 2002
    • (2002) Cancer Res , vol.62 , pp. 4963-4967
    • Gordon, G.J.1    Jensen, R.V.2    Hsiao, L.L.3
  • 249
    • 0037142053 scopus 로고    scopus 로고
    • The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
    • Rosenwald A, Wright G, Chan WC, et al: The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N Engl J Med 346:1937-1947, 2002
    • (2002) N Engl J Med , vol.346 , pp. 1937-1947
    • Rosenwald, A.1    Wright, G.2    Chan, W.C.3
  • 250
    • 4243364103 scopus 로고    scopus 로고
    • Gene expression profiles for docetaxel chemosensitivity
    • abstr 1969
    • Chang JC, Woolen E, Elledge RM, et al: Gene expression profiles for docetaxel chemosensitivity. Proc Am Soc Oncol 21:426a, 2002 (abstr 1969)
    • (2002) Proc Am Soc Oncol , vol.21
    • Chang, J.C.1    Woolen, E.2    Elledge, R.M.3
  • 251
    • 0038297500 scopus 로고    scopus 로고
    • Expression profiles of non-small cell lung cancers on cDNA microarrays: Identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs
    • Kikuchi T, Daigo Y, Katagiri T, et al: Expression profiles of non-small cell lung cancers on cDNA microarrays: Identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs. Oncogene 22:2192-2205, 2003
    • (2003) Oncogene , vol.22 , pp. 2192-2205
    • Kikuchi, T.1    Daigo, Y.2    Katagiri, T.3
  • 252
    • 3543092544 scopus 로고    scopus 로고
    • Global gene expression profiling from formalin-fixed paraffin-embedded (FFPE) tissues; implications for retrospective and prospective clinical studies
    • abstr 498
    • Erlander MG, Ellis MJ, Olson J, et al: Global gene expression profiling from formalin-fixed paraffin-embedded (FFPE) tissues; implications for retrospective and prospective clinical studies. Proc Am Soc Clin Oncol 22:125, 2003 (abstr 498)
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 125
    • Erlander, M.G.1    Ellis, M.J.2    Olson, J.3
  • 253
    • 2442659386 scopus 로고    scopus 로고
    • Prognostic value of proliferation, apoptosis, defective DNA mismatch repair, and p53 overexpression in patients with resected Dukes' B2 or C colon cancer: A North Central Cancer Treatment Group Study
    • Garrity MM, Burgart LJ, Mahoney MR, et al: Prognostic value of proliferation, apoptosis, defective DNA mismatch repair, and p53 overexpression in patients with resected Dukes' B2 or C colon cancer: A North Central Cancer Treatment Group Study. J Clin Oncol 22:1572-1582, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 1572-1582
    • Garrity, M.M.1    Burgart, L.J.2    Mahoney, M.R.3
  • 254
    • 0037440051 scopus 로고    scopus 로고
    • Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
    • Allegra CJ, Paik S, Colangelo LH, et al: Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J Clin Oncol 21:241-250, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 241-250
    • Allegra, C.J.1    Paik, S.2    Colangelo, L.H.3
  • 255
    • 0035879210 scopus 로고    scopus 로고
    • Value of epidermal growth factor receptor, HER2, p53, and steroid receptors in predicting the efficacy of tamoxifen in high-risk postmenopausal breast cancer patients
    • Knoop AS, Bentzen SM, Nielsen MM, et al: Value of epidermal growth factor receptor, HER2, p53, and steroid receptors in predicting the efficacy of tamoxifen in high-risk postmenopausal breast cancer patients. J Clin Oncol 19:3376-3384, 2001
    • (2001) J Clin Oncol , vol.19 , pp. 3376-3384
    • Knoop, A.S.1    Bentzen, S.M.2    Nielsen, M.M.3
  • 256
    • 0034684075 scopus 로고    scopus 로고
    • Role of alpha1 acid glycoprotein in the in vivo resistance of human BCR-ABL(+) leukemic cells to the abl inhibitor STI571
    • Gambacorti-Passerini C, Barni R, le Coutre P, et al: Role of alpha1 acid glycoprotein in the in vivo resistance of human BCR-ABL(+) leukemic cells to the abl inhibitor STI571. J Natl Cancer Inst 92:1641-1650, 2000
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1641-1650
    • Gambacorti-Passerini, C.1    Barni, R.2    Le Coutre, P.3
  • 257
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • Gorre ME, Mohammed M, Ellwood K, et al: Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 293:876-880, 2001
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3
  • 258
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350:2129-2139, 2004
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3


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