Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: Molecular mechanisms that determine lower expression in cultured cells

Xenobiotica

Volumn 32, Issue 6, 2002, Pages 505-520

  Rodriguez Antona C ^a   Donato, M T ^b   Boobis, A ^c   Edwards, R J ^c   Watts, P S ^c   Castell, J V ^a,b   Gomez Lechon M J ^b  

^a Facultad de Medicina   (Spain)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

^c IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; 7 ETHOXYCOUMARIN; COUMARIN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DEXTROMETHORPHAN; DICLOFENAC; ETHOXYRESORUFIN; MESSENGER RNA; NUCLEAR RNA; RESORUFIN DERIVATIVE; TESTOSTERONE; TRANSCRIPTION FACTOR;

ARTICLE; BIOTRANSFORMATION; CANCER CELL CULTURE; DRUG METABOLISM; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL CULTURE; PROTEIN CONTENT; PROTEIN EXPRESSION; RNA ANALYSIS;

BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HELA CELLS; HEPATOCYTES; HUMANS; INDICATORS AND REAGENTS; INTRONS; LIVER NEOPLASMS; PHARMACEUTICAL PREPARATIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TESTOSTERONE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0036301269     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250210128675     Document Type: Article

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